Jason T Motz

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Model-based biological Raman spectral imaging
    Karen E Shafer-Peltier
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    J Cell Biochem Suppl 39:125-37. 2002
  2. ncbi request reprint Optical fiber probe for biomedical Raman spectroscopy
    Jason T Motz
    George R Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Appl Opt 43:542-54. 2004
  3. ncbi request reprint Spectral- and frequency-encoded fluorescence imaging
    Jason T Motz
    Harvard Medical School and the Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Opt Lett 30:2760-2. 2005
  4. ncbi request reprint Real-time Raman system for in vivo disease diagnosis
    Jason T Motz
    Massachusetts Institute of Technology, George R Harrison Spectroscopy Laboratory, Cambridge, Massachusetts 02138, USA
    J Biomed Opt 10:031113. 2005
  5. ncbi request reprint In vivo Raman spectral pathology of human atherosclerosis and vulnerable plaque
    Jason T Motz
    Massachusetts General Hospital, Harvard Medical School, Wellman Center for Photomedicine, Boston, Massachusetts 02114, USA
    J Biomed Opt 11:021003. 2006
  6. doi request reprint Intrinsic versus laser-induced fluorescence spectroscopy for coronary atherosclerosis: a generational comparison model for testing diagnostic accuracy
    George O Angheloiu
    Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Appl Spectrosc 66:1403-10. 2012
  7. ncbi request reprint Detection of morphological markers of vulnerable atherosclerotic plaque using multimodal spectroscopy
    Obrad R Scepanovic
    Massachusetts Institute of Technology, G R Harrison Spectroscopy Laboratory, Cambridge, Massachusetts 02139, USA
    J Biomed Opt 11:021007. 2006
  8. ncbi request reprint Intrinsic fluorescence and diffuse reflectance spectroscopy identify superficial foam cells in coronary plaques prone to erosion
    George O Angheloiu
    Spectroscopy Laboratory, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA
    Arterioscler Thromb Vasc Biol 26:1594-600. 2006
  9. pmc Characterization of atherosclerotic plaques by laser speckle imaging
    Seemantini K Nadkarni
    Department of Dermatology, Harvard Medical School, Wellman Center for Photomedicine, Massachusetts General Hospital, 40 Blossom St, BAR 718, Boston, MA 02114, USA
    Circulation 112:885-92. 2005

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Model-based biological Raman spectral imaging
    Karen E Shafer-Peltier
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    J Cell Biochem Suppl 39:125-37. 2002
    ..How to best extract meaningful chemical information using each imaging approach will be discussed and examples of images produced with each will be shown...
  2. ncbi request reprint Optical fiber probe for biomedical Raman spectroscopy
    Jason T Motz
    George R Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Appl Opt 43:542-54. 2004
    ..Performance has been tested through simulations and experiments with tissue models and several in vitro tissue types, demonstrating that this new design can advance Raman spectroscopy as a clinically practical technique...
  3. ncbi request reprint Spectral- and frequency-encoded fluorescence imaging
    Jason T Motz
    Harvard Medical School and the Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Opt Lett 30:2760-2. 2005
    ..This method is applicable for developing submillimeter diameter endoscopes. The principles of the technique are validated by imaging indocyanine green fluorescence in microfluidic channels...
  4. ncbi request reprint Real-time Raman system for in vivo disease diagnosis
    Jason T Motz
    Massachusetts Institute of Technology, George R Harrison Spectroscopy Laboratory, Cambridge, Massachusetts 02138, USA
    J Biomed Opt 10:031113. 2005
    ..The real-time capabilities of the system were demonstrated in vivo during femoral bypass and breast lumpectomy surgeries. Such a system will greatly facilitate the adoption of Raman spectroscopy into clinical research and practice...
  5. ncbi request reprint In vivo Raman spectral pathology of human atherosclerosis and vulnerable plaque
    Jason T Motz
    Massachusetts General Hospital, Harvard Medical School, Wellman Center for Photomedicine, Boston, Massachusetts 02114, USA
    J Biomed Opt 11:021003. 2006
    ..These initial findings indicate that Raman spectroscopy has the potential to be a clinically relevant diagnostic tool for studying cardiovascular disease...
  6. doi request reprint Intrinsic versus laser-induced fluorescence spectroscopy for coronary atherosclerosis: a generational comparison model for testing diagnostic accuracy
    George O Angheloiu
    Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Appl Spectrosc 66:1403-10. 2012
    ..87 ± 0.025, superior to LIF(342) (84% ± 3% and 0.84 ± 0.016; P = 0.0002 and 0.02, respectively) in a generational comparison model...
  7. ncbi request reprint Detection of morphological markers of vulnerable atherosclerotic plaque using multimodal spectroscopy
    Obrad R Scepanovic
    Massachusetts Institute of Technology, G R Harrison Spectroscopy Laboratory, Cambridge, Massachusetts 02139, USA
    J Biomed Opt 11:021007. 2006
    ..The results indicate that MMS provides depth-sensitive and complementary morphological information about plaque composition. A prospective in vivo study will be conducted to validate these findings...
  8. ncbi request reprint Intrinsic fluorescence and diffuse reflectance spectroscopy identify superficial foam cells in coronary plaques prone to erosion
    George O Angheloiu
    Spectroscopy Laboratory, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA
    Arterioscler Thromb Vasc Biol 26:1594-600. 2006
    ..This is a key step in our ongoing program to develop a spectroscopic technique for real-time in vivo diagnosis of vulnerable atherosclerotic plaque...
  9. pmc Characterization of atherosclerotic plaques by laser speckle imaging
    Seemantini K Nadkarni
    Department of Dermatology, Harvard Medical School, Wellman Center for Photomedicine, Massachusetts General Hospital, 40 Blossom St, BAR 718, Boston, MA 02114, USA
    Circulation 112:885-92. 2005
    ..In this article, we describe a new optical technique, laser speckle imaging (LSI), that measures an index of plaque viscoelasticity. We evaluate the potential of LSI for characterizing atherosclerotic plaque...