Samia Mora

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA)
    Samia Mora
    Center for Cardiovascular Disease Prevention, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Atherosclerosis 192:211-7. 2007
  2. ncbi request reprint Interaction of body mass index and framingham risk score in predicting incident coronary disease in families
    Samia Mora
    Center for Cardiovascular Disease Prevention, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave East, 3rd Floor, Boston, MA 02215, USA
    Circulation 111:1871-6. 2005
  3. ncbi request reprint Enhanced risk assessment in asymptomatic individuals with exercise testing and Framingham risk scores
    Samia Mora
    Center for Cardiovascular Disease Prevention, Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical Schoo, Boston, MA, USA
    Circulation 112:1566-72. 2005
  4. ncbi request reprint Association of physical activity and body mass index with novel and traditional cardiovascular biomarkers in women
    Samia Mora
    Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02215, USA
    JAMA 295:1412-9. 2006
  5. ncbi request reprint Additive value of immunoassay-measured fibrinogen and high-sensitivity C-reactive protein levels for predicting incident cardiovascular events
    Samia Mora
    Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215
    Circulation 114:381-7. 2006
  6. pmc Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms
    Samia Mora
    Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Circulation 116:2110-8. 2007
  7. pmc On-treatment non-high-density lipoprotein cholesterol, apolipoprotein B, triglycerides, and lipid ratios in relation to residual vascular risk after treatment with potent statin therapy: JUPITER (justification for the use of statins in prevention: an inte
    Samia Mora
    Center for Cardiovascular Disease Prevention, Divisions of Preventive and Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Am Coll Cardiol 59:1521-8. 2012
  8. pmc High-density lipoprotein cholesterol, size, particle number, and residual vascular risk after potent statin therapy
    Samia Mora
    Center for Cardiovascular Disease Prevention, Division of Preventive Medicine S M, R J G, P MR and Division of Cardiovascular Medicine S M, P MR, Brigham and Women s Hospital, Harvard Medical School, Boston, MA and Department of Biostatistics, Harvard School of Public Health, Boston, MA R J G
    Circulation 128:1189-97. 2013
  9. doi request reprint HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial
    Paul M Ridker
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Lancet 376:333-9. 2010
  10. pmc The fat-mass and obesity-associated (FTO) gene, physical activity, and risk of incident cardiovascular events in white women
    Tariq Ahmad
    Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Am Heart J 160:1163-9. 2010

Collaborators

Detail Information

Publications38

  1. ncbi request reprint LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA)
    Samia Mora
    Center for Cardiovascular Disease Prevention, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Atherosclerosis 192:211-7. 2007
    ..Previous studies showing that smaller low-density lipoprotein (LDL) size is associated with greater atherosclerotic risk did not adequately control for small and large LDL particle correlation...
  2. ncbi request reprint Interaction of body mass index and framingham risk score in predicting incident coronary disease in families
    Samia Mora
    Center for Cardiovascular Disease Prevention, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave East, 3rd Floor, Boston, MA 02215, USA
    Circulation 111:1871-6. 2005
    ..The aim of this study was to examine the effect of high BMI on incident CHD in white and black families with premature CHD and to estimate the heritability of BMI...
  3. ncbi request reprint Enhanced risk assessment in asymptomatic individuals with exercise testing and Framingham risk scores
    Samia Mora
    Center for Cardiovascular Disease Prevention, Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical Schoo, Boston, MA, USA
    Circulation 112:1566-72. 2005
    ..We hypothesized that risk prediction could be improved with 2 non-ECG exercise test measures, exercise capacity (metabolic equivalents, or METs) and heart rate recovery (HRR)...
  4. ncbi request reprint Association of physical activity and body mass index with novel and traditional cardiovascular biomarkers in women
    Samia Mora
    Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02215, USA
    JAMA 295:1412-9. 2006
    ..There are few data directly comparing the effects of physical activity and body weight on cardiovascular biomarkers...
  5. ncbi request reprint Additive value of immunoassay-measured fibrinogen and high-sensitivity C-reactive protein levels for predicting incident cardiovascular events
    Samia Mora
    Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215
    Circulation 114:381-7. 2006
    ..Whether other inflammatory biomarkers, such as fibrinogen, add further prognostic information is uncertain...
  6. pmc Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms
    Samia Mora
    Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Circulation 116:2110-8. 2007
    ..Although the precise mechanisms underlying this inverse association are unclear, differences in several cardiovascular risk factors may mediate this effect...
  7. pmc On-treatment non-high-density lipoprotein cholesterol, apolipoprotein B, triglycerides, and lipid ratios in relation to residual vascular risk after treatment with potent statin therapy: JUPITER (justification for the use of statins in prevention: an inte
    Samia Mora
    Center for Cardiovascular Disease Prevention, Divisions of Preventive and Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Am Coll Cardiol 59:1521-8. 2012
    ....
  8. pmc High-density lipoprotein cholesterol, size, particle number, and residual vascular risk after potent statin therapy
    Samia Mora
    Center for Cardiovascular Disease Prevention, Division of Preventive Medicine S M, R J G, P MR and Division of Cardiovascular Medicine S M, P MR, Brigham and Women s Hospital, Harvard Medical School, Boston, MA and Department of Biostatistics, Harvard School of Public Health, Boston, MA R J G
    Circulation 128:1189-97. 2013
    ..Little is known about alternative HDL measures such as HDL size or particle number (HDL-P) as determinants of residual risk after potent statin therapy...
  9. doi request reprint HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial
    Paul M Ridker
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Lancet 376:333-9. 2010
    ..We addressed, using the JUPITER trial cohort, whether this association remains when LDL-cholesterol concentrations are reduced to the very low ranges with high-dose statin treatment...
  10. pmc The fat-mass and obesity-associated (FTO) gene, physical activity, and risk of incident cardiovascular events in white women
    Tariq Ahmad
    Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Am Heart J 160:1163-9. 2010
    ..However, its association with cardiovascular disease (CVD) in healthy populations and any interaction with physical activity remain unclear...
  11. pmc Lipoprotein particle size and concentration by nuclear magnetic resonance and incident type 2 diabetes in women
    Samia Mora
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusett, USA
    Diabetes 59:1153-60. 2010
    ..We examined the association of lipoprotein particle size and concentration measured by nuclear magnetic resonance (NMR) spectroscopy with clinical type 2 diabetes...
  12. doi request reprint Statins for the primary prevention of cardiovascular events in women with elevated high-sensitivity C-reactive protein or dyslipidemia: results from the Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUP
    Samia Mora
    Center for Cardiovascular Disease Prevention, Divisions of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Circulation 121:1069-77. 2010
    ..We analyzed sex-specific outcomes in the Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) and synthesized the results with prior trials...
  13. pmc Lifestyle interaction with fat mass and obesity-associated (FTO) genotype and risk of obesity in apparently healthy U.S. women
    Tariq Ahmad
    Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Diabetes Care 34:675-80. 2011
    ..Variation in the fat mass and obesity-associated (FTO) gene is associated with obesity. The extent to which separate and combined effects of physical activity and caloric intake modify this association remains unclear...
  14. pmc Exercise blood pressure and future cardiovascular death in asymptomatic individuals
    Sandra A Weiss
    Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
    Circulation 121:2109-16. 2010
    ..Individuals with exaggerated exercise blood pressure (BP) tend to develop future hypertension. It is controversial whether they have higher risk of death from cardiovascular disease (CVD)...
  15. pmc Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women
    Samia Mora
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue E, Boston, MA 02215, USA
    Circulation 119:931-9. 2009
    ..Nuclear magnetic resonance (NMR) spectroscopy measures the number and size of lipoprotein particles instead of their cholesterol or triglyceride content, but its clinical utility is uncertain...
  16. pmc Lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER Trial (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin)
    Amit V Khera
    Division of Preventive Medicine A V K, B M E, P M R, S M and Division of Cardiovascular Medicine B M E, P M R, S M, Brigham and Women s Hospital, Harvard Medical School, Boston, MA and Quest Diagnostics Nichols Institute, San Juan Capistrano, CA M P C, F M H, J W
    Circulation 129:635-42. 2014
    ..Statins may offset the risk associated with elevated Lp(a), but it is unknown whether Lp(a) is a determinant of residual risk in the setting of low low-density lipoprotein cholesterol after potent statin therapy...
  17. pmc Levels and changes of HDL cholesterol and apolipoprotein A-I in relation to risk of cardiovascular events among statin-treated patients: a meta-analysis
    S Matthijs Boekholdt
    Departments of Cardiology S M B and Vascular Medicine B J A, G K H, J J P K, Academic Medical Center, Amsterdam, The Netherlands Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Boston, MA S M, P M R Center of Preventive Medicine, Oslo University Hospital, Ullevål and University of Oslo, Norway T R P State University of New York Health Science Center, Brooklyn, NY J C L Rosalind Franklin University of Medicine and Science, North Chicago, IL K M A W Department of Neurology and Stroke Center, Bichat University Hospital, Paris, France P A Global Pharmaceuticals Pfizer, New York, NY D A D Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia A M T Department of Biochemistry and Lipid Clinic, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia D R S NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia A K Medical Research Institute, University of Dundee, Dundee, United Kingdom H M C Centre for Diabetes, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom G A H Department of Medicine, Royal Free and University College Medical School, London, United Kingdom D J B School of Biomedicine
    Circulation 128:1504-12. 2013
    ..It is also unknown whether a rise in HDL-C or apoA-I after initiation of statin therapy is associated with a reduced cardiovascular risk...
  18. pmc Lipoprotein subclass abnormalities and incident hypertension in initially healthy women
    Nina P Paynter
    Divisions of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Clin Chem 57:1178-87. 2011
    ..Whether lipoprotein particle size or subclass concentrations play a role in the development of hypertension is unknown...
  19. pmc Lipoprotein(a) and risk of type 2 diabetes
    Samia Mora
    Center for Cardiovascular Disease Prevention, Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Clin Chem 56:1252-60. 2010
    ..Previous studies have demonstrated that cardiovascular risk is higher with increased lipoprotein(a) [Lp(a)]. Whether Lp(a) concentration is related to type 2 diabetes is unclear...
  20. pmc Comparison of LDL cholesterol concentrations by Friedewald calculation and direct measurement in relation to cardiovascular events in 27,331 women
    Samia Mora
    Division of Preventive Medicine, Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Clin Chem 55:888-94. 2009
    ....
  21. pmc Determinants of residual risk in secondary prevention patients treated with high- versus low-dose statin therapy: the Treating to New Targets (TNT) study
    Samia Mora
    Brigham and Women s Hospital, Boston, MA 02215, USA
    Circulation 125:1979-87. 2012
    ..Risk factors for this "residual risk" have not been studied comprehensively. We aimed to identify determinants of this risk above and beyond lipid-related risk factors...
  22. pmc Fasting compared with nonfasting lipids and apolipoproteins for predicting incident cardiovascular events
    Samia Mora
    Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Circulation 118:993-1001. 2008
    ..Whether fasting status alters associations of nontriglyceride lipids with CVD is unclear...
  23. ncbi request reprint Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
    Sandeep Bansal
    Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, Boston, MA 02215, USA
    JAMA 298:309-16. 2007
    ..Although triglyceride levels are typically obtained in the fasting state, postprandial hypertriglyceridemia may play an important role in atherosclerosis...
  24. doi request reprint A national interactive web-based physical activity intervention in women, evaluation of the american heart association choose to move program 2006-2007
    Sarah B Lieber
    Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 109:1754-60. 2012
    ..Increasing use of this simple Web-based tool could improve PA and promote disease prevention...
  25. ncbi request reprint Homocysteine, 5,10-methylenetetrahydrofolate reductase 677C>T polymorphism, nutrient intake, and incident cardiovascular disease in 24,968 initially healthy women
    Robert Y L Zee
    Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin Chem 53:845-51. 2007
    ..To address this apparent paradox, we explored whether interaction between genetic and dietary factors related to homocysteine metabolism contributes to CVD risk...
  26. pmc Value of reserve pulse pressure in improving the risk stratification of patients with normal myocardial perfusion imaging
    Deepak Thomas
    the Noninvasive Cardiovascular Imaging Program, Department of Medicine Cardiology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Eur Heart J 34:2074-81a. 2013
    ....
  27. pmc Association of high-density lipoprotein cholesterol with incident cardiovascular events in women, by low-density lipoprotein cholesterol and apolipoprotein B100 levels: a cohort study
    Samia Mora
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann Intern Med 155:742-50. 2011
    ..Whether this observation is consistent across low-density lipoprotein cholesterol (LDL-C) levels or total atherogenic particle burden (apolipoprotein B100) is less well-studied, particularly in women...
  28. doi request reprint The clinical utility of high-sensitivity C-reactive protein in cardiovascular disease and the potential implication of JUPITER on current practice guidelines
    Samia Mora
    Divisions of Preventive and Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin Chem 55:219-28. 2009
    ....
  29. ncbi request reprint Gender-specific prediction of cardiac disease: importance of risk factors and exercise variables
    Sandra D'Amore
    Division of Preventive Medicine, Brigham and Women s Hospital Harvard Medical School, Boston, Massachusetts 02215, USA
    Cardiol Rev 14:281-5. 2006
    ....
  30. ncbi request reprint Ability of exercise testing to predict cardiovascular and all-cause death in asymptomatic women: a 20-year follow-up of the lipid research clinics prevalence study
    Samia Mora
    Ciccarone Preventive Cardiology Center, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    JAMA 290:1600-7. 2003
    ..The value of exercise testing in women has been questioned...
  31. doi request reprint Discordance of low-density lipoprotein (LDL) cholesterol with alternative LDL-related measures and future coronary events
    Samia Mora
    Divisions of Preventive S M, J E B, P M R and Cardiovascular Medicine S M, P M R, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    Circulation 129:553-61. 2014
    ..However, the clinical utility of these measures may only become apparent among individuals for whom levels are inconsistent (discordant) with LDL-C...
  32. ncbi request reprint Blood pressure and risk of developing type 2 diabetes mellitus: the Women's Health Study
    David Conen
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Eur Heart J 28:2937-43. 2007
    ..To examine the relationship of blood pressure (BP) and BP progression with the subsequent development of type 2 diabetes...
  33. ncbi request reprint Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER)--can C-reactive protein be used to target statin therapy in primary prevention?
    Samia Mora
    Center for Cardiovascular Disease Prevention and Division of Cardiovascular Disease, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Cardiol 97:33A-41A. 2006
    ..Ongoing work will determine whether hs-CRP reduction, independent of LDL cholesterol reduction, results in a net clinical benefit...
  34. pmc Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis
    Daniel I Chasman
    Donald W Reynolds Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS Genet 5:e1000730. 2009
    ....
  35. pmc High-density lipoprotein particle subclass heterogeneity and incident coronary heart disease
    Akintunde O Akinkuolie
    Divisions of Preventive Medicine and Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    Circ Cardiovasc Qual Outcomes 7:55-63. 2014
    ..We prospectively evaluated the association of HDL subclasses, defined by a recently proposed nomenclature, with incident coronary heart disease (CHD)...
  36. ncbi request reprint Biomarkers for prediction of cardiovascular events
    Diane M Becker
    N Engl J Med 356:1473; author reply 1474-5. 2007
  37. ncbi request reprint The metabolic syndrome in women
    J Gabriel Schneider
    Ciccarone Center for the Prevention of Heart Disease, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Cardiol Rev 14:286-91. 2006
    ..Appropriate treatment may also include managing individual cardiac risk factors with the use of antihypertensive and lipid-modifying agents among others...
  38. ncbi request reprint Glucose levels in the normal range predict incident diabetes in families with premature coronary heart disease
    Stasia S Reynolds
    Divisions of General Internal Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Diabetes Res Clin Pract 74:267-73. 2006
    ..Little is known about excess risk of incident diabetes conferred by fasting plasma glucose (FPG) within the normal range (<5.6 mmol/l) for high risk families...