Research Topics
Genomes and GenesSpecies | M C MonuteauxSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
Does social class predict substance problems in young adults with ADHD?Michael C Monuteaux
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Am J Addict 16:403-9. 2007..No significant association was found in controls. These findings indicate that substance use risk in ADHD subjects is especially vulnerable to social class...
Genetic risk for conduct disorder symptom subtypes in an ADHD sample: specificity to aggressive symptomsMichael C Monuteaux
Massachusetts General Hospital, Boston, MA 02114, USA
J Am Acad Child Adolesc Psychiatry 48:757-64. 2009..The aim of this study was to examine the role of the COMT and SLC6A4 genes in the risk for CD and its symptomatic subtypes in the context of ADHD...
Specificity in the familial aggregation of overt and covert conduct disorder symptoms in a referred attention-deficit hyperactivity disorder sampleM C Monuteaux
Pediatric Psychopharmacology Unit, Psychiatry Department, Massachusetts General Hospital, Boston, MA 02114, USA
Psychol Med 34:1113-27. 2004....
The influence of sex on the course and psychiatric correlates of ADHD from childhood to adolescence: a longitudinal studyMichael C Monuteaux
Clinical and Research Programs in Pediatric Psychiatry and Adult ADHD, Psychiatry Department, Massachusetts General Hospital, Boston, MA 02114, USA
J Child Psychol Psychiatry 51:233-41. 2010..The purpose of this study was to examine the effect of sex on the course and psychiatric correlates of ADHD from childhood into adolescence...
A preliminary study of dopamine D4 receptor genotype and structural brain alterations in adults with ADHDMichael C Monuteaux
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Am J Med Genet B Neuropsychiatr Genet 147:1436-41. 2008..These result support the heterogeneity of ADHD and provides insights as to its underlying pathophysiology...
The familial association between cigarette smoking and ADHD: a study of clinically referred girls with and without ADHD, and their familiesMichael C Monuteaux
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
Nicotine Tob Res 10:1549-58. 2008..These findings support the hypothesis that the combination of ADHD and smoking comprises an etiologically distinct familial subtype of ADHD in girls...
A randomized, placebo-controlled clinical trial of bupropion for the prevention of smoking in children and adolescents with attention-deficit/hyperactivity disorderMichael C Monuteaux
Pediatric Psychopharmacology Program, Massachusetts General Hospital, USA
J Clin Psychiatry 68:1094-101. 2007....
Maternal smoking during pregnancy and offspring overt and covert conduct problems: a longitudinal studyMichael C Monuteaux
Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114 2696, USA
J Child Psychol Psychiatry 47:883-90. 2006..We further investigated this association, attending to overt and covert CD symptom subtypes. Also, we tested whether gender and socioeconomic status (SES) modified this association...
Predictors, clinical characteristics, and outcome of conduct disorder in girls with attention-deficit/hyperactivity disorder: a longitudinal studyMichael C Monuteaux
The Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Psychol Med 37:1731-41. 2007..However, it is unclear how these results extend to females. Our aim was to examine the predictors, clinical characteristics, and functional outcome of CD in a sample of female youth with and without ADHD...
Gender effects on attention-deficit/hyperactivity disorder in adults, revisitedJoseph Biederman
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Biol Psychiatry 55:692-700. 2004..These results bear striking similarities to findings reported in pediatric samples, supporting the validity of ADHD and stressing the importance of identifying and treating the disorder in adulthood...
The long-term longitudinal course of oppositional defiant disorder and conduct disorder in ADHD boys: findings from a controlled 10-year prospective longitudinal follow-up studyJ Biederman
Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
Psychol Med 38:1027-36. 2008....
Familial transmission of derived phenotypes for molecular genetic studies of substance use disordersStephen V Faraone
Department of Psychiatry, SUNY Upstate Medical University, 750 East Adams St, Syracuse, NY 13210, USA
Drug Alcohol Depend 92:100-7. 2008..001; cognitive impairment: OR=1.33, p=0.04); in offspring, baseline psychopathology predicted SUD at follow-up assessments (OR=1.55, p=0.01). Results suggest that these candidate SUD phenotypes may be useful for genetic studies of SUD...
Assessing symptoms of attention deficit hyperactivity disorder in children and adults: which is more valid?S V Faraone
Massachusetts General Hospital, Boston 02114, USA
J Consult Clin Psychol 68:830-42. 2000..They do not support the idea that parents of ADHD children are biased to report ADHD symptoms in themselves because of their exposure to an ADHD child...
Social impairment in girls with ADHD: patterns, gender comparisons, and correlatesR W Greene
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston 02114, USA
J Am Acad Child Adolesc Psychiatry 40:704-10. 2001....
Impact of gender and age on executive functioning: do girls and boys with and without attention deficit hyperactivity disorder differ neuropsychologically in preteen and teenage years?Larry J Seidman
Pediatric Psychopharmacology Unit, Psychiatry Service, Massachusetts General Hospital, Boston, MA 02114, USA
Dev Neuropsychol 27:79-105. 2005..These findings suggest that executive dysfunctions are correlates of ADHD regardless of gender and age, at least through the late teen years...
Can a subtype of conduct disorder linked to bipolar disorder be identified? Integration of findings from the Massachusetts General Hospital Pediatric Psychopharmacology Research ProgramJoseph Biederman
Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA
Biol Psychiatry 53:952-60. 2003..Our data suggest that when BPD and CD co-occur in children, both are correctly diagnosed. In these comorbid cases, CD symptoms should not be viewed as secondary to BPD, and manic symptoms should not be viewed as secondary to CD...
Methodological complexities in the diagnosis of major depression in youth: an analysis of mother and youth self-reportsE B Braaten
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA
J Child Adolesc Psychopharmacol 11:395-407. 2001..To this end we evaluated whether morbidity and functional correlates on the diagnosis of MDD in youth vary by informant source...
Psychiatric comorbidity, family dysfunction, and social impairment in referred youth with oppositional defiant disorderRoss W Greene
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, ACC 725, Boston, MA 02114, USA
Am J Psychiatry 159:1214-24. 2002..The authors sought to achieve an improved understanding of the diagnosis of oppositional defiant disorder independent of its association with conduct disorder...
Differential effect of environmental adversity by gender: Rutter's index of adversity in a group of boys and girls with and without ADHDJoseph Biederman
Psychiatry Department, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
Am J Psychiatry 159:1556-62. 2002..This study examined the effect of gender in mediating the association between environmental adversity and the risk of attention deficit hyperactivity disorder (ADHD) and associated impairments...
A pilot controlled clinical trial of ABT-418, a cholinergic agonist, in the treatment of adults with attention deficit hyperactivity disorderT E Wilens
Pediatric Psychopharmacology Clinic, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
Am J Psychiatry 156:1931-7. 1999..Recent reports have suggested the potential usefulness of cholinergic agents for ADHD. To this end, the authors completed a controlled study of ABT-418, a novel cholinergic activating agent, for the treatment of adults with ADHD...
A controlled clinical trial of bupropion for attention deficit hyperactivity disorder in adultsT E Wilens
Pediatric Psychopharmacology Clinic, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Psychiatry 158:282-8. 2001..The authors report results from a controlled investigation to determine the anti-ADHD efficacy of bupropion in adult patients with DSM-IV ADHD...
Long-term stability of the Child Behavior Checklist in a clinical sample of youth with attention deficit hyperactivity disorderJ Biederman
Harvard Medical School, Massachusetts General Hospital and McLean Hospital, Boston, MA, USA
J Clin Child Psychol 30:492-502. 2001..These results support the informativeness of the CBCL as a useful measure of longitudinal course in clinical samples of youth with ADHD...
Heterogeneity of childhood conduct disorder: further evidence of a subtype of conduct disorder linked to bipolar disorderJ Wozniak
Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
J Affect Disord 64:121-31. 2001..Furthermore, they suggest that the comorbid condition of CD+BPD may be a distinct nosological entity. This suggests that clinicians treating CD or BPD children should consider the treatment implications of this comorbid condition...
Parsing the associations between prenatal exposure to nicotine and offspring psychopathology in a nonreferred sampleJoseph Biederman
Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Adolesc Health 45:142-8. 2009..The main aim of this study was to disentangle the association between maternal smoking during pregnancy with psychopathological outcomes, adjusting for possible confounders...
The CBCL as a screen for psychiatric comorbidity in paediatric patients with ADHDJ Biederman
Pediatric Psychopharmacology Research Program, Massachusetts General Hospital, Yawkey Center for Patient Care YAW 6A 6900, Boston, MA 02114, USA
Arch Dis Child 90:1010-5. 2005..It was hypothesised that specific scales of the CBCL would help identify specific comorbidities within ADHD cases in the primary care setting...
Attention deficit hyperactivity disorder with bipolar disorder in girls: further evidence for a familial subtype?S V Faraone
Pediatric Psychopharmacology Unit, Psychiatry Service, ACC 725, Massachusetts General Hospital, Fruit Street, Boston, MA 02114, USA
J Affect Disord 64:19-26. 2001..To clarify the nosologic status of girls with attention deficit hyperactivity disorder (ADHD) who also satisfy diagnostic criteria for bipolar disorder (BPD)...
Sex differences in the functional neuroanatomy of working memory in adults with ADHDEve M Valera
Department of Psychiatry, Massachusetts General Hospital, 149 13th St, Charlestown, MA 02129, USA
Am J Psychiatry 167:86-94. 2010..The authors examined sex differences in the neural functioning of adults with ADHD during performance of a verbal working memory task...
Psychiatric comorbidity and functioning in clinically referred preschool children and school-age youths with ADHDTimothy E Wilens
Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
J Am Acad Child Adolesc Psychiatry 41:262-8. 2002..We evaluated the clinical characteristics, psychiatric comorbidity, and functioning of preschool children and school-age youths with ADHD referred to a pediatric psychiatric clinic for evaluation...
Towards further understanding of the co-morbidity between attention deficit hyperactivity disorder and bipolar disorder: a MRI study of brain volumesJ Biederman
Clinical and Research Program in Pediatric Psychopharmacology, Psychiatry Department, Massachusetts General Hospital, Boston, MA 02114, USA
Psychol Med 38:1045-56. 2008....
Neuropsychological functioning in girls with attention-deficit/hyperactivity disorder with and without learning disabilitiesLarry J Seidman
Massachusetts General Hospital, Boston, MA 02114, USA
Neuropsychology 20:166-77. 2006..These results extend to females the previously documented association of LDs with neuropsychological functioning in males with ADHD...
Learning disabilities and executive dysfunction in boys with attention-deficit/hyperactivity disorderL J Seidman
Department of Psychiatry, Harvard Medical School at Massachusetts General Hospital, Boston 02114, USA
Neuropsychology 15:544-56. 2001..These data indicate that comorbid LD, especially arithmetic disability, significantly increases the severity of executive function impairment in ADHD...
Impact of exposure to parental attention-deficit hyperactivity disorder on clinical features and dysfunction in the offspringJ Biederman
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
Psychol Med 32:817-27. 2002..However, since exposure to parental ADHD was associated with a disruptive family environment, the identification and treatment of adults with ADHD may be an important component of the treatment plan of youth with ADHD...
Stimulant therapy and risk for subsequent substance use disorders in male adults with ADHD: a naturalistic controlled 10-year follow-up studyJoseph Biederman
Research Program in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital, Boston 02114, USA biederman helix mgh harvard edu
Am J Psychiatry 165:597-603. 2008..The authors examined the association between stimulant treatment in childhood and adolescence and subsequent substance use disorders (alcohol, drug, and nicotine) into the young adult years...
Familial risk analyses of attention deficit hyperactivity disorder and substance use disordersJoseph Biederman
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, 55 Fruit St, Warren 705, Boston, MA 02114, USA
Am J Psychiatry 165:107-15. 2008..A robust and bidirectional comorbidity between attention deficit hyperactivity disorder (ADHD) and psychoactive substance use disorder (alcohol or drug abuse or dependence) has been consistently reported in the extant literature...
Representativeness of participants in a clinical trial for attention-deficit/hyperactivity disorder? Comparison with adults from a large observational studyCraig B H Surman
Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Ste 2000, 185 Alewife Brook Pkwy, Cambridge, MA 02138, USA
J Clin Psychiatry 71:1612-6. 2010..In particular, exclusion criteria may frequently exclude individuals with comorbid mental health conditions, which are common in the adult ADHD population...
Are girls with ADHD at risk for eating disorders? Results from a controlled, five-year prospective studyJoseph Biederman
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, MA 02114, USA
J Dev Behav Pediatr 28:302-7. 2007..To evaluate the association between attention-deficit/hyperactivity disorder (ADHD) and eating disorders in a large adolescent population of girls with and without ADHD...
Further evidence of an association between adolescent bipolar disorder with smoking and substance use disorders: a controlled studyTimothy E Wilens
Massachusetts General Hospital, Pediatric Psychopharmacology Unit, Boston, MA 02114, USA
Drug Alcohol Depend 95:188-98. 2008..Clinicians should carefully screen adolescents with bipolar disorder for substance and cigarette use...
New insights into the comorbidity between ADHD and major depression in adolescent and young adult femalesJoseph Biederman
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, MA 02114, USA
J Am Acad Child Adolesc Psychiatry 47:426-34. 2008..The main aim of this study was to evaluate the association between attention-deficit/hyperactivity disorder (ADHD) and major depression (MD) in adolescent and young adult females...
Parsing the familiality of oppositional defiant disorder from that of conduct disorder: a familial risk analysisCarter R Petty
Massachusetts General Hospital, Boston, MA 02114, USA
J Psychiatr Res 43:345-52. 2009..Family risk analysis can provide an improved understanding of the association between attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD), attending to the comorbidity with conduct disorder (CD)...
Adult psychiatric outcomes of girls with attention deficit hyperactivity disorder: 11-year follow-up in a longitudinal case-control studyJoseph Biederman
Clinical and Research Programs in Pediatric Psychopharmacology, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Psychiatry 167:409-17. 2010..Few follow-up studies have been conducted of girls with ADHD, and none have followed girls into adulthood. The authors sought to estimate the prevalence of psychopathology in girls with and without ADHD followed into young adulthood...
Effect of candidate gene polymorphisms on the course of attention deficit hyperactivity disorderJoseph Biederman
Pediatric Psychopharmacology Department, Massachusetts General Hospital, Boston, MA, USA
Psychiatry Res 170:199-203. 2009..94) and 5HTTLPR long allele. Our findings suggest that the DRD4 7-repeat allele is associated with a more persistent course of ADHD...
A naturalistic 10-year prospective study of height and weight in children with attention-deficit hyperactivity disorder grown up: sex and treatment effectsJoseph Biederman
Clinical and Research Programs in Pediatric Psychiatry and Adult ADHD, Psychiatry Department, Massachusetts General Hospital, and Department of Psychiatry, Harvard Medical School, Boston, MA 02114, USA
J Pediatr 157:635-40, 640.e1. 2010..To assess the effect of attention-deficit/hyperactivity disorder (ADHD) and its treatment on growth outcomes in children followed into adulthood...
Do stimulants protect against psychiatric disorders in youth with ADHD? A 10-year follow-up studyJoseph Biederman
Psychiatry Department, Massachusetts General Hospital, Clinical and Research Programs in PediatricPsychopharmacology and Adult ADHD, Boston, Massachusetts 02114, USA
Pediatrics 124:71-8. 2009..We tested the association between stimulant treatment and the subsequent development of psychiatric comorbidity in a longitudinal sample of patients with ADHD...
The Child Behavior Checklist-Pediatric Bipolar Disorder profile predicts a subsequent diagnosis of bipolar disorder and associated impairments in ADHD youth growing up: a longitudinal analysisJoseph Biederman
Clinical and Research Program in Pediatric Psychopharmacology, Yawkey Center, Suite 6A, Massachusetts General Hospital, Boston, MA 02114, USA
J Clin Psychiatry 70:732-40. 2009..To examine the predictive utility of the Child Behavior Checklist-Pediatric Bipolar Disorder (CBCL-PBD) profile to help identify children at risk for bipolar disorder...
Familial risk analysis of the association between attention-deficit/hyperactivity disorder and psychoactive substance use disorder in female adolescents: a controlled studyJoseph Biederman
Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
J Child Psychol Psychiatry 50:352-8. 2009..However, this literature has been based almost exclusively on male only samples and, therefore, the findings may not generalize to females...
The longitudinal course of comorbid oppositional defiant disorder in girls with attention-deficit/hyperactivity disorder: findings from a controlled 5-year prospective longitudinal follow-up studyJoseph Biederman
Pediatric Psychopharmacology Unit of the Psychiatry Department, Massachusetts General Hospital, Boston, MA 02114, USA
J Dev Behav Pediatr 29:501-7. 2008..However, most of the available information on the subject derives from predominantly male samples. This study evaluated the longitudinal course and impact of comorbid ODD in a large sample of girls with ADHD...
Examination of concordance between maternal and youth reports in the diagnosis of pediatric bipolar disorderJoseph Biederman
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, 55 Fruit Street, Warren 705, Boston, MA 02114, USA
Bipolar Disord 11:298-306. 2009..To this end we compared discordant (mother positive and youth negative) and concordant (mother and youth positive) cases...
Effect of prior stimulant treatment for attention-deficit/hyperactivity disorder on subsequent risk for cigarette smoking and alcohol and drug use disorders in adolescentsTimothy E Wilens
Pediatric Psychopharmacology Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Arch Pediatr Adolesc Med 162:916-21. 2008..To examine the effects of early stimulant treatment on subsequent risk for cigarette smoking and substance use disorders (SUDs) in adolescents with attention-deficit/hyperactivity disorder (ADHD)...
Characteristics of adolescents and young adults with ADHD who divert or misuse their prescribed medicationsTimothy E Wilens
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, MA 02114, USA
J Am Acad Child Adolesc Psychiatry 45:408-14. 2006..As part of a 10-year longitudinal study of youths with ADHD, the authors evaluated medication diversion or misuse at the last follow-up period...
The clinical dilemma of using medications in substance-abusing adolescents and adults with attention-deficit/hyperactivity disorder: what does the literature tell us?Timothy E Wilens
Clinical Research Program in Pediatric Psychopharmacology, Pediatric Psychopharmacology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Child Adolesc Psychopharmacol 15:787-98. 2005..The role of pharmacological treatment for ADHD in these comorbid individuals remains unclear...
Functional impairments in adults with self-reports of diagnosed ADHD: A controlled study of 1001 adults in the communityJoseph Biederman
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Yawkey Center for Outpatient Care, Boston, MA 02114, USA
J Clin Psychiatry 67:524-40. 2006..The objective of this study was to evaluate functional impairments in a nonreferred sample of adults identifying themselves as having been diagnosed with attention-deficit/hyperactivity disorder (ADHD) by a clinician in their community...
Psychopathology in females with attention-deficit/hyperactivity disorder: a controlled, five-year prospective studyJoseph Biederman
Pediatric Psychopharmacology Unit of the Psychiatry Department, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA
Biol Psychiatry 60:1098-105. 2006..This study estimated the lifetime burden of comorbid psychopathology in a large sample of girls with and without ADHD followed up over five years...
Does referral bias impact findings in high-risk offspring for anxiety disorders? A controlled study of high-risk children of non-referred parents with panic disorder/agoraphobia and major depressionJoseph Biederman
Pediatric Psychopharmacology Program and the Department of Psychiatry, Massachusetts General Hospital, Warren 705, 15 Parkman St, Boston, MA 02114, USA
J Affect Disord 82:209-16. 2004..This study evaluated whether these patterns of transmission between parents and high-risk offspring are moderated by referral bias...
Is cigarette smoking a gateway to alcohol and illicit drug use disorders? A study of youths with and without attention deficit hyperactivity disorderJoseph Biederman
Department of Psychiatry, Harvard Medical School, USA
Biol Psychiatry 59:258-64. 2006....
Impact of executive function deficits and attention-deficit/hyperactivity disorder (ADHD) on academic outcomes in childrenJoseph Biederman
Pediatric Psychopharmacology Unit, Psychiatry Department, Massachusetts General Hospital, Boston, MA 02114, USA
J Consult Clin Psychol 72:757-66. 2004..Children and adolescents with ADHD and EFDs were found to be at high risk for significant impairments in academic functioning. These results support screening children with ADHD for EFDs to prevent academic failure...
Utility of an abbreviated questionnaire to identify individuals with ADHD at risk for functional impairmentsJoseph Biederman
Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Psychiatr Res 42:304-10. 2008....
Informativeness of maternal reports on the diagnosis of ADHD: an analysis of mother and youth reportsJoseph Biederman
Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
J Atten Disord 10:410-7. 2007..We evaluated correlates of the diagnosis of ADHD in youth by informant source...
How informative are parent reports of attention-deficit/hyperactivity disorder symptoms for assessing outcome in clinical trials of long-acting treatments? A pooled analysis of parents' and teachers' reportsJoseph Biederman
Pediatric Psychopharmacology Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Pediatrics 113:1667-71. 2004..This study compares the ability of parent and teacher reports to document change during clinical trials of long-acting treatments...
Do individuals with ADHD self-medicate with cigarettes and substances of abuse? Results from a controlled family study of ADHDTimothy E Wilens
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Am J Addict 16:14-21; quiz 22-3. 2007..More than one-third of adolescents and young adults endorsed using cigarettes and substances for self medication. Studies clarifying the role of self-medication in substance use disorders are necessary...
Growth deficits and attention-deficit/hyperactivity disorder revisited: impact of gender, development, and treatmentJoseph Biederman
Pediatric Psychopharmacology Unit of the Psychiatry Department, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts 02114, USA
Pediatrics 111:1010-6. 2003..Although the relationship between putative growth deficits and attention-deficit/hyperactivity disorder (ADHD) has been examined in boys, this issue has not been evaluated in girls...
CBCL clinical scales discriminate ADHD youth with structured-interview derived diagnosis of oppositional defiant disorder (ODD)Joseph Biederman
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, MA 02114, USA
J Atten Disord 12:76-82. 2008....
Young adult outcome of attention deficit hyperactivity disorder: a controlled 10-year follow-up studyJoseph Biederman
Pediatric Psychopharmacology Unit of the Psychiatry Department, Massachusetts General Hospital, Boston, MA 02114, USA
Psychol Med 36:167-79. 2006..Our objective was to estimate the lifetime prevalence of psychopathology in a sample of youth with and without attention deficit hyperactivity disorder (ADHD) through young adulthood using contemporaneous diagnostic and analytic techniques...
Toward guidelines for pedigree selection in genetic studies of attention deficit hyperactivity disorderS V Faraone
Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston 02114, USA
Genet Epidemiol 18:1-16. 2000..This paper shows that these sub-phenotypes are useful for molecular genetic studies because (1) they have much higher empirical lambda values and (2) they affect a substantial minority of ADHD patients...
Effect of dopamine transporter gene (SLC6A3) variation on dorsal anterior cingulate function in attention-deficit/hyperactivity disorderAriel B Brown
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
Am J Med Genet B Neuropsychiatr Genet 153:365-75. 2010..Alterations in activation of attention and EF networks found previously to be involved in ADHD are likely influenced by SLC6A3 genotype. This genotype may contribute to heterogeneity of brain alterations found within ADHD samples...
Parsing the comorbidity between bipolar disorder and anxiety disorders: a familial risk analysisJanet Wozniak
Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
J Child Adolesc Psychopharmacol 12:101-11. 2002..Thus, we investigated the familial association between BPD and ANX among the first-degree relatives of children with BPD with and without comorbid ANX...
Does parental ADHD bias maternal reports of ADHD symptoms in children?Stephen V Faraone
Department of Psychiatry, Harvard Medical School at Massachusetts General Hospital, Boston 02114, USA
J Consult Clin Psychol 71:168-75. 2003..Results were similar across child gender or referral status. These results do not support the notion that parental ADHD affects maternal reports of offspring ADHD...
Prescribing patterns for treatment of pediatric bipolar disorder in a specialty clinicMona P Potter
Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
J Child Adolesc Psychopharmacol 19:529-38. 2009..The aim of this study was to describe prescribing practices in the treatment of pediatric bipolar disorder in a university practice setting...
Revisiting the association between attention-deficit/hyperactivity disorder and anxiety disorders: a familial risk analysisEllen B Braaten
Pediatric Psychopharmacology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114-3139, USA
Biol Psychiatry 53:93-9. 2003..CONCLUSIONS: These findings are most consistent with the hypothesis that ADHD and anxiety disorders segregate independently in families...
Effectiveness of collaborative problem solving in affectively dysregulated children with oppositional-defiant disorder: initial findingsRoss W Greene
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
J Consult Clin Psychol 72:1157-64. 2004..These improvements were in all instances equivalent, and in many instances superior, to the improvements produced by PT. Implications of these findings for further research on and treatment selection in children with ODD are discussed...
Deriving phenotypes for molecular genetic studies of substance use disorders: a family study approachStephen V Faraone
Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY 13210, USA
Drug Alcohol Depend 88:244-50. 2007..Results provide some support for the idea that candidate SUD phenotypes such as psychopathology and cognitive functioning, which are external to the diagnostic criteria for SUDs, may be useful for genetic studies of SUD...
Further evidence for the diagnostic continuity between child and adolescent ADHDStephen Faraone
Pediatric Psychopharmacology Unit, Psychiatry Service, Massachusetts General Hospital, Boston, MA 02114, USA
J Atten Disord 6:5-13. 2002..To determine if there are differences in the clinical expression and correlates of ADHD between children and adolescents...
Reexamining the familial association between asthma and ADHD in girlsPaul Hammerness
Massachusetts General Hospital and Harvard Medical School, MA 02114, USA
J Atten Disord 8:136-43. 2005..These findings further support the conclusion that ADHD symptoms should not be dismissed as part of asthma symptomatology or a consequence of its treatment...
Anterior cingulate volumetric alterations in treatment-naïve adults with ADHD: a pilot studyNikos Makris
Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
J Atten Disord 13:407-13. 2010..Thus its anatomical alteration may give rise to impulsivity, hyperactivity and inattention, which are cardinal behavioral manifestations of ADHD...
Towards conceptualizing a neural systems-based anatomy of attention-deficit/hyperactivity disorderNikos Makris
Harvard Medical School Department of Psychiatry, Boston University School of Medicine, Boston, MA 02129, USA
Dev Neurosci 31:36-49. 2009..Characterizing these neural systems using neuroimaging could be critical for the description of structural endophenotypes, and may provide the capability of in vivo categorization and correlation with behavior and genes...
ADHD and dyscalculia: Evidence for independent familial transmissionMichael C Monuteaux
Massachusetts General Hospital, Pediatric Psychopharmacology Program, Boston, 02114, USA
J Learn Disabil 38:86-93. 2005..These results reinforce the current nosological approach to these disorders and underscore the need for separate identification and treatment strategies for children with both conditions...
Dorsolateral prefrontal and anterior cingulate cortex volumetric abnormalities in adults with attention-deficit/hyperactivity disorder identified by magnetic resonance imagingLarry J Seidman
Harvard Medical School, Department of Psychiatry, Center for Morphometric Analysis, Massachusetts General Hospital, Fruit Street, Boston, MA 02114, USA
Biol Psychiatry 60:1071-80. 2006..This structural MRI study used an a priori region of interest approach...
Attention and executive systems abnormalities in adults with childhood ADHD: A DT-MRI study of connectionsNikos Makris
Harvard Medical School Departments of Neurology and Radiology Services, Center for Morphometric Analysis, Massachusetts General Hospital, Boston, MA 02129, USA
Cereb Cortex 18:1210-20. 2008..The demonstration of FA abnormalities in the CB and SLF II in adults with childhood ADHD provides further support for persistent structural abnormalities into adulthood...
Correlates of ADHD among children in pediatric and psychiatric clinicsBetsy Busch
Department of Pediatrics, Tufts University School of Medicine in Boston, USA
Psychiatr Serv 53:1103-11. 2002..These findings suggest that children cared for in pediatric practice have similar levels of comorbidity and dysfunction as psychiatrically referred youth...
Diagnosing adult attention deficit hyperactivity disorder: are late onset and subthreshold diagnoses valid?Stephen V Faraone
Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, 750 East Adams St, Syracuse, NY 13210, USA
Am J Psychiatry 163:1720-9; quiz 1859. 2006....
Comparing ADHD in velocardiofacial syndrome to idiopathic ADHD: a preliminary studyKevin M Antshel
SUNY Upstate Medical University, NY, USA
J Atten Disord 11:64-73. 2007..Children with velocardiofacial syndrome (VCFS), a contiguous deletion syndrome, have an increased prevalence of attention deficit/hyperactivity disorder (ADHD)...
