Joseph Misdraji

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Gastric epithelial dysplasia
    Joseph Misdraji
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
    Semin Diagn Pathol 19:20-30. 2002
  2. ncbi request reprint Miscellaneous conditions of the appendix
    Joseph Misdraji
    James Homer Wright Pathology Laboratories, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Semin Diagn Pathol 21:151-63. 2004
  3. ncbi request reprint Protocol for the examination of specimens from patients with invasive carcinomas of the appendix
    Joseph Misdraji
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Pathol Lab Med 130:1433-9. 2006
  4. ncbi request reprint Appendiceal mucinous neoplasms: controversial issues
    Joseph Misdraji
    Department of Pathology, Massachusetts General Hospital, Boston 02114, USA
    Arch Pathol Lab Med 134:864-70. 2010
  5. ncbi request reprint Primary follicular lymphoma of the gastrointestinal tract
    Joseph Misdraji
    The James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 35:1255-63. 2011
  6. ncbi request reprint Psammoma bodies in cervicovaginal cytology specimens: a clinicopathological analysis of 31 cases
    Joseph Misdraji
    Department of Pathology and Cytopathology Laboratory, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Gynecol Oncol 103:238-46. 2006
  7. ncbi request reprint Primary epithelial neoplasms and other epithelial lesions of the appendix (excluding carcinoid tumors)
    Joseph Misdraji
    James Homer Wright Pathology Laboratories, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Semin Diagn Pathol 21:120-33. 2004
  8. ncbi request reprint Defective mismatch repair in the pathogenesis of low-grade appendiceal mucinous neoplasms and adenocarcinomas
    Joseph Misdraji
    James Homer Wright Pathology Laboratories at the Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Mod Pathol 17:1447-54. 2004
  9. ncbi request reprint Appendiceal mucinous neoplasms: a clinicopathologic analysis of 107 cases
    Joseph Misdraji
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 27:1089-103. 2003
  10. ncbi request reprint Autoimmune hepatitis with centrilobular necrosis
    Joseph Misdraji
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 28:471-8. 2004

Detail Information

Publications44

  1. ncbi request reprint Gastric epithelial dysplasia
    Joseph Misdraji
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
    Semin Diagn Pathol 19:20-30. 2002
    ..We also discuss new classifications of gastric epithelial dysplasia designed to develop equivalence between grading schemes worldwide...
  2. ncbi request reprint Miscellaneous conditions of the appendix
    Joseph Misdraji
    James Homer Wright Pathology Laboratories, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Semin Diagn Pathol 21:151-63. 2004
    ..Occasionally, however, appendiceal neoplasia that is secondary from another site may dominate the clinical picture and lead to potential pathologic misdiagnosis as primary appendiceal disease...
  3. ncbi request reprint Protocol for the examination of specimens from patients with invasive carcinomas of the appendix
    Joseph Misdraji
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Pathol Lab Med 130:1433-9. 2006
  4. ncbi request reprint Appendiceal mucinous neoplasms: controversial issues
    Joseph Misdraji
    Department of Pathology, Massachusetts General Hospital, Boston 02114, USA
    Arch Pathol Lab Med 134:864-70. 2010
    ..Finally, the controversy about the most effective treatment of patients with pseudomyxoma peritonei is discussed...
  5. ncbi request reprint Primary follicular lymphoma of the gastrointestinal tract
    Joseph Misdraji
    The James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 35:1255-63. 2011
    ..Follicular lymphoma (FL), a common nodal lymphoma, is rare in the gastrointestinal (GI) tract. We report our experience with primary FL of the GI tract...
  6. ncbi request reprint Psammoma bodies in cervicovaginal cytology specimens: a clinicopathological analysis of 31 cases
    Joseph Misdraji
    Department of Pathology and Cytopathology Laboratory, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Gynecol Oncol 103:238-46. 2006
    ..Psammoma bodies in cervicovaginal cytology specimens are associated with malignant and benign conditions. Few studies have evaluated which features distinguish patients with underlying malignancy from those with benign conditions...
  7. ncbi request reprint Primary epithelial neoplasms and other epithelial lesions of the appendix (excluding carcinoid tumors)
    Joseph Misdraji
    James Homer Wright Pathology Laboratories, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Semin Diagn Pathol 21:120-33. 2004
    ..Retention cysts, hyperplastic polyps, and diffuse mucosal hyperplasia, although not necessarily neoplastic, are reviewed here as they may enter into the differential diagnosis of appendiceal mucinous neoplasms...
  8. ncbi request reprint Defective mismatch repair in the pathogenesis of low-grade appendiceal mucinous neoplasms and adenocarcinomas
    Joseph Misdraji
    James Homer Wright Pathology Laboratories at the Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Mod Pathol 17:1447-54. 2004
    ..Defective DNA mismatch was found in 11% of invasive carcinomas, likely due to a germline mutation. These findings suggest that sporadic appendiceal neoplasia rarely arises through the defective DNA mismatch repair (mutator) pathway...
  9. ncbi request reprint Appendiceal mucinous neoplasms: a clinicopathologic analysis of 107 cases
    Joseph Misdraji
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 27:1089-103. 2003
    ....
  10. ncbi request reprint Autoimmune hepatitis with centrilobular necrosis
    Joseph Misdraji
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 28:471-8. 2004
    ..Unlike other causes of zone 3 hepatitis, AIH is steroid responsive; therefore, timely diagnosis is important...
  11. ncbi request reprint EMR for Barrett's esophagus-related superficial neoplasms offers better diagnostic reproducibility than mucosal biopsy
    Mari Mino-Kenudson
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Gastrointest Endosc 66:660-6; quiz 767, 769. 2007
    ..It also allows for better pathologic grading compared with mucosal biopsy specimens. However, the interobserver variation in the interpretation of EMR specimens has not been tested...
  12. ncbi request reprint Case records of the Massachusetts General Hospital. Case 3-2006. A 63-year-old woman with jaundice and a pancreatic mass
    Robert H Schapiro
    Gastrointestinal Unit, Massachusetts General Hospital, USA
    N Engl J Med 354:398-406. 2006
  13. pmc The absence of obstructive sleep apnea may protect against non-alcoholic fatty liver in patients undergoing bariatric surgery
    Kathleen E Corey
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 8:e62504. 2013
    ..While risk factors for steatohepatitis have been identified, little work has been performed to identify factors protective against NAFLD development...
  14. doi request reprint Ruptured appendiceal diverticula mimicking low-grade appendiceal mucinous neoplasms
    Maylee Hsu
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Am J Surg Pathol 33:1515-21. 2009
    ..Failure to distinguish this process from a mucosal neoplasm with rupture may result in unnecessary therapy and cause the patient undue alarm...
  15. ncbi request reprint Sessile serrated adenoma: challenging discrimination from other serrated colonic polyps
    Alton B Farris
    Department of Pathology, Biostatistics Center, Massachusetts General Hospital, Boston, MA, USA
    Am J Surg Pathol 32:30-5. 2008
    ..However, this level of variability is acceptable because the presence of SSA indicates increased risk of developing additional serrated polyps and carcinoma, and surveillance is appropriate...
  16. ncbi request reprint Case records of the Massachusetts General Hospital. Case 33-2006. A 43-year-old man with diabetes, hypogonadism, cirrhosis, arthralgias, and fatigue
    Raymond T Chung
    Gastrointestinal Unit, Massachusetts General Hospital, USA
    N Engl J Med 355:1812-9. 2006
  17. doi request reprint Longitudinal clinical evaluation of a novel antibody cocktail for detection of high-grade squamous intraepithelial lesions on cervical cytology specimens
    Rosemary H Tambouret
    James Homer Wright Pathology Laboratory, Division of Cytopathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Pathol Lab Med 132:918-25. 2008
    ..Although cervical cancer screening by cytology is successful, the test continues to show relatively poor operating characteristics. Cell cycle markers may enhance detection of high-grade squamous intraepithelial lesions...
  18. ncbi request reprint Management of superficial Barrett's epithelium-related neoplasms by endoscopic mucosal resection: clinicopathologic analysis of 27 cases
    Mari Mino-Kenudson
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 29:680-6. 2005
    ..This is a significant advantage since it can modify patients' management. However, frequent incompleteness of resection and high persistence/recurrence are significant pitfalls that dictate continued endoscopic surveillance...
  19. ncbi request reprint Appendiceal or cecal endometriosis with intestinal metaplasia: a potential mimic of appendiceal mucinous neoplasms
    Joseph Misdraji
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA Hospital Pathology Associates, Virginia Piper Cancer Institute, Minneapolis, MN Department of Pathology, University of British Columbia, BC, Canada
    Am J Surg Pathol 38:698-705. 2014
    ..6 y). Endometriosis with intestinal metaplasia is a rare phenomenon that, when it occurs in the appendix or cecum, may lead to misdiagnosis as a low-grade appendiceal mucinous neoplasm or mucinous carcinoma. ..
  20. pmc Non-high-density lipoprotein cholesterol as a biomarker for nonalcoholic steatohepatitis
    Kathleen E Corey
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Gastroenterol Hepatol 10:651-6. 2012
    ..Non-high-density lipoprotein-cholesterol (non-HDL-C) encompasses all apolipoprotein-B-containing lipoproteins, including VLDL, and can be calculated from standard lipid panels without additional cost...
  21. doi request reprint Cytologic features of endocervical glandular lesions: comparison of SurePath, ThinPrep, and conventional smear specimen preparations
    Nicole A Belsley
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Diagn Cytopathol 36:232-7. 2008
    ..Keeping these differences in mind, virtually the same criteria can be used to identify endocervical glandular lesions in all three specimen types...
  22. ncbi request reprint Nonalcoholic steatohepatitis is associated with an atherogenic lipoprotein subfraction profile
    Kathleen E Corey
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, USA
    Lipids Health Dis 13:100. 2014
    ..We sought to evaluate whether differences in lipoprotein subfractions in obese patients with and without NASH contributes to this difference in CVD risk...
  23. doi request reprint A histopathologic pattern of centrilobular hepatocyte injury suggests 6-mercaptopurine-induced hepatotoxicity in patients with inflammatory bowel disease
    Ricard Masia
    Department of Pathology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Arch Pathol Lab Med 136:618-22. 2012
    ..A variety of histopathologic findings have been observed in patients with inflammatory bowel disease with thiopurine-induced hepatotoxicity, including nodular regenerative hyperplasia, vascular injury, and cholestasis...
  24. doi request reprint Congenital portosystemic shunts: imaging findings and clinical presentations in 11 patients
    Angelos A Konstas
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit St, Boston, MA 02114, United States
    Eur J Radiol 80:175-81. 2011
    ..To evaluate the clinical anatomy and presentations of congenital portosystemic shunts, and determine features that promote recognition on imaging...
  25. doi request reprint Eosinophilic esophagitis in children: a pathologic or clinicopathologic diagnosis?
    Matthew T Brigger
    Department of Otolaryngology Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Arch Otolaryngol Head Neck Surg 135:95-100. 2009
    ..To determine the accuracy of histopathologic diagnosis in distinguishing eosinophilic esophagitis (EE) from gastroesophageal reflux disease (GERD) in children with upper aerodigestive symptoms...
  26. doi request reprint De novo autoimmune hepatitis during immune reconstitution in an HIV-infected patient receiving highly active antiretroviral therapy
    Jacqueline G O'Leary
    Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Clin Infect Dis 46:e12-4. 2008
    ..We report, to our knowledge, the first case of autoimmune hepatitis caused by immune reconstitution...
  27. ncbi request reprint Congenital extrahepatic portosystemic shunts (Abernethy malformation): a histopathologic evaluation
    Mikhail Lisovsky
    Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Am J Surg Pathol 35:1381-90. 2011
    ..Abernethy malformation may also be associated with hepatocellular carcinoma and focal nodular hyperplasia in some patients...
  28. ncbi request reprint Pneumatosis intestinalis: a challenging biopsy diagnosis
    Aashiyana Koreishi
    James Homer Wright Pathology Laboratory at the Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 31:1469-75. 2007
    ..In biopsy material, though, the diagnosis is more challenging, as giant cells and histiocytes can be interpreted as granulomatous inflammation indicative of other conditions such as infection or Crohn disease...
  29. ncbi request reprint Case records of the Massachusetts General Hospital. Case 15-2006. A 46-year-old woman with sudden onset of abdominal distention
    Raymond T Chung
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, USA
    N Engl J Med 354:2166-75. 2006
  30. doi request reprint Pancreatic mucinous cystic neoplasm of the main pancreatic duct
    Ricard Masia
    Department of Pathology and Laboratory Medicine, Massachusetts General Hospital, Boston, 02114 2696, USA
    Arch Pathol Lab Med 135:264-7. 2011
    ..Pancreatic mucinous cystic neoplasm involving the entire main pancreatic duct has not, to our knowledge, been previously reported...
  31. ncbi request reprint Liver environment and HCV replication affect human T-cell phenotype and expression of inhibitory receptors
    Daniela C Kroy
    Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts
    Gastroenterology 146:550-61. 2014
    ..We investigated the relationship between T-cell location, expression of inhibitory receptors, maturation, and viral control using blood and liver T cells from patients with hepatitis C virus (HCV) and other viral infections...
  32. doi request reprint Identification of tissue contamination by polymorphic deletion probe fluorescence in situ hybridization
    Sarah Chiang
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Harvard School of Public Health, Boston, MA 02114, USA
    Am J Surg Pathol 36:1464-71. 2012
    ....
  33. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-2004. A 48-year-old man with recurrent gastrointestinal bleeding
    Myles D Keroack
    Gastroenterology Unit, Massachusetts General Hospital, USA
    N Engl J Med 351:488-95. 2004
  34. pmc Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations
    David C Wilbur
    Department of Pathology, James Homer Wright Pathology Laboratories, Massachusetts General Hospital, and the Department of Pathology, Harvard Medical School, Boston, MA 02114, USA
    Arch Pathol Lab Med 133:1949-53. 2009
    ..Before implementation, technical issues, pathologist adaptability, and morphologic pitfalls must be well characterized...
  35. ncbi request reprint Case records of the Massachusetts General Hospital. Case 25-2005. A 40-year-old man with prolonged fever and weight loss
    Dennis L Kasper
    Department of Medicine, Brigham and Women s Hospital, Boston, USA
    N Engl J Med 353:713-22. 2005
  36. pmc The effect of angiotensin-blocking agents on liver fibrosis in patients with hepatitis C
    Kathleen E Corey
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Liver Int 29:748-53. 2009
    ..Multiple studies implicate the renin-angiotensin system in hepatic fibrogenesis. Few studies have examined the effects of angiotensin blockade on liver fibrosis via human histology...
  37. ncbi request reprint Adrenocortical carcinoma: contrast washout characteristics on CT
    James M A Slattery
    Department of Abdominal Imaging and Interventional Radiology, Massachusetts General Hospital, 55 Fruit St, White 270C, Boston, MA 02114, USA
    AJR Am J Roentgenol 187:W21-4. 2006
    ..The purpose of this study was to characterize pathologically proven adrenocortical carcinoma by examination of washout attenuation characteristics on contrast-enhanced CT images...
  38. pmc Secondary causes of nonalcoholic fatty liver disease
    Jacob M Kneeman
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, USA
    Therap Adv Gastroenterol 5:199-207. 2012
    ....
  39. doi request reprint An improved method of surgical pathology testing for onychomycosis
    Rosalynn M Nazarian
    Pathology Service, James Homer Wright Pathology Laboratories, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Acad Dermatol 66:655-60. 2012
    ..However, routine histopathological methods of processing nail clippings can be limited by poor section quality, higher costs, and delayed turnaround times for some specimens because of tissue hardness...
  40. pmc Decreased CXCR3+ CD8 T cells in advanced human immunodeficiency virus infection suggest that a homing defect contributes to cytotoxic T-lymphocyte dysfunction
    Diana M Brainard
    Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA 02129, USA
    J Virol 81:8439-50. 2007
    ..These data suggest that both CXCR3(+) CD8 T cells and LN CXCR3 ligands decrease as HIV infection progresses, resulting in reduced homing of CTL into LNs and contributing to immune dysfunction...
  41. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 8-2004. A 28-year-old man with abdominal pain, fever, and a mass in the region of the pancreas
    William R Brugge
    Gastroenterology Unit, Department of Medicine, Massachusetts General Hospital, USA
    N Engl J Med 350:1131-8. 2004
  42. ncbi request reprint Adenosquamous carcinoma of the pancreas: cytologic features in 14 cases
    Aliyah Rahemtullah
    The James Homer Wright Pathology Laboratories and Cytopathology Laboratory at the Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Cancer 99:372-8. 2003
    ..In the current study, the authors describe their experience with the fine-aspiration biopsy (FNAB) diagnosis of ASCa and characterize cytologic features in 14 cases...
  43. ncbi request reprint A comprehensive study of nondysplastic and dysplastic serrated polyps of the vermiform appendix
    Rhonda K Yantiss
    Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA
    Am J Surg Pathol 31:1742-53. 2007
    ..These features, including BRAF mutations, may be more closely related to a serrated morphology in appendiceal polyps rather than biologically important changes...
  44. ncbi request reprint Epstein-Barr virus hepatitis: diagnostic value of in situ hybridization, polymerase chain reaction, and immunohistochemistry on liver biopsy from immunocompetent patients
    Namsoo Suh
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Am J Surg Pathol 31:1403-9. 2007
    ..However, EBER-positive cells can be sparse and easily overlooked. Immunohistochemistry for EBV latent membrane proteins apparently has no utility in the diagnosis of EBV hepatitis...