Nikolaus R McFarland

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Comparison of transduction efficiency of recombinant AAV serotypes 1, 2, 5, and 8 in the rat nigrostriatal system
    Nikolaus R McFarland
    MassGeneral Institute for Neurodegenerative Disease MIND, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129 4404, USA
    J Neurochem 109:838-45. 2009
  2. pmc Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease
    Nikolaus R McFarland
    MassGeneral Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129 4404, USA
    J Neuropathol Exp Neurol 68:515-24. 2009
  3. pmc Postmortem brain levels of urate and precursors in Parkinson's disease and related disorders
    Nikolaus R McFarland
    Center for Translational Research in Neurodegenerative Disease, Department of Neurology, University of Florida College of Medicine, Gainesville, Fla, USA
    Neurodegener Dis 12:189-98. 2013

Detail Information

Publications3

  1. pmc Comparison of transduction efficiency of recombinant AAV serotypes 1, 2, 5, and 8 in the rat nigrostriatal system
    Nikolaus R McFarland
    MassGeneral Institute for Neurodegenerative Disease MIND, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129 4404, USA
    J Neurochem 109:838-45. 2009
    ..New rAAV serotypes thus promise improved gene delivery to nigrostriatal system with the potential for better models and therapeutics for Parkinson disease and other neurodegenerative disorders...
  2. pmc Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease
    Nikolaus R McFarland
    MassGeneral Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129 4404, USA
    J Neuropathol Exp Neurol 68:515-24. 2009
    ..Further study is needed to clarify the effects of these S129 mutants and alpha-synuclein phosphorylation in mammalian systems...
  3. pmc Postmortem brain levels of urate and precursors in Parkinson's disease and related disorders
    Nikolaus R McFarland
    Center for Translational Research in Neurodegenerative Disease, Department of Neurology, University of Florida College of Medicine, Gainesville, Fla, USA
    Neurodegener Dis 12:189-98. 2013
    ..In Parkinson's disease (PD) higher, but still normal, levels of blood and cerebrospinal fluid urate have been associated with a lower rate of disease progression...