K McCall

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi request reprint Facing death in the fly: genetic analysis of apoptosis in Drosophila
    K McCall
    Howard Hughes Medical Institute, Cambridge, MA, USA
    Trends Genet 13:222-6. 1997
  2. pmc Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function
    L Goyal
    Howard Hughes Medical Institute, Massachusetts Institute of Technology, Departments of Biology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    EMBO J 19:589-97. 2000
  3. ncbi request reprint The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling
    A Bergmann
    Massachusetts Institute of Technology, Howard Hughes Medical Institute, Department of Biology, Cambridge 02139, USA
    Cell 95:331-41. 1998
  4. ncbi request reprint DCP-1, a Drosophila cell death protease essential for development
    Z Song
    Howard Hughes Medical Institute, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Science 275:536-40. 1997
  5. ncbi request reprint Requirement for DCP-1 caspase during Drosophila oogenesis
    K McCall
    Howard Hughes Medical Institute, Department of Biology, 31 Ames Street, 68 430, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Science 279:230-4. 1998
  6. ncbi request reprint Stage-specific regulation of caspase activity in drosophila oogenesis
    J S Peterson
    Department of Biology, Boston University, 5 Cummington Street, Boston, MA 02215, USA
    Dev Biol 260:113-23. 2003
  7. ncbi request reprint The Drosophila caspases Strica and Dronc function redundantly in programmed cell death during oogenesis
    J S Baum
    Department of Biology, Graduate Program, Boston University, Boston, MA 02215, USA
    Cell Death Differ 14:1508-17. 2007
  8. pmc Probes of chromatin accessibility in the Drosophila bithorax complex respond differently to Polycomb-mediated repression
    K McCall
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    EMBO J 15:569-80. 1996
  9. pmc Enhancer traps in the Drosophila bithorax complex mark parasegmental domains
    K McCall
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115
    Genetics 138:387-99. 1994
  10. ncbi request reprint Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector
    E Bier
    Howard Hughes Medical Institute, San Francisco, California
    Genes Dev 3:1273-87. 1989

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Facing death in the fly: genetic analysis of apoptosis in Drosophila
    K McCall
    Howard Hughes Medical Institute, Cambridge, MA, USA
    Trends Genet 13:222-6. 1997
    ....
  2. pmc Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function
    L Goyal
    Howard Hughes Medical Institute, Massachusetts Institute of Technology, Departments of Biology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    EMBO J 19:589-97. 2000
    ..These data provide strong in vivo evidence for a previously published model of cell death regulation in Drosophila...
  3. ncbi request reprint The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling
    A Bergmann
    Massachusetts Institute of Technology, Howard Hughes Medical Institute, Department of Biology, Cambridge 02139, USA
    Cell 95:331-41. 1998
    ..These findings define a novel mechanism by which growth factor signaling directly inactivates a critical component of the intrinsic cell death machinery. These studies provide further insights into the function of ras as an oncogene...
  4. ncbi request reprint DCP-1, a Drosophila cell death protease essential for development
    Z Song
    Howard Hughes Medical Institute, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Science 275:536-40. 1997
    ..Loss of zygotic DCP-1 function in Drosophila caused larval lethality and melanotic tumors, showing that this gene is essential for normal development...
  5. ncbi request reprint Requirement for DCP-1 caspase during Drosophila oogenesis
    K McCall
    Howard Hughes Medical Institute, Department of Biology, 31 Ames Street, 68 430, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Science 279:230-4. 1998
    ..The dcp-1- phenotype suggests that the cytoskeletal and nuclear events in the nurse cells make use of the machinery normally associated with apoptosis and that apoptosis of the nurse cells is a necessary event for oocyte development...
  6. ncbi request reprint Stage-specific regulation of caspase activity in drosophila oogenesis
    J S Peterson
    Department of Biology, Boston University, 5 Cummington Street, Boston, MA 02215, USA
    Dev Biol 260:113-23. 2003
    ..This limited caspase activation in dying nurse cells may prevent destruction of the nurse cell cytoskeleton and the connected oocyte...
  7. ncbi request reprint The Drosophila caspases Strica and Dronc function redundantly in programmed cell death during oogenesis
    J S Baum
    Department of Biology, Graduate Program, Boston University, Boston, MA 02215, USA
    Cell Death Differ 14:1508-17. 2007
    ..This reveals a novel pathway of cell death in the ovary that utilizes strica, dronc, dcp-1 and drice, and importantly illustrates strong redundancy among the caspases...
  8. pmc Probes of chromatin accessibility in the Drosophila bithorax complex respond differently to Polycomb-mediated repression
    K McCall
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    EMBO J 15:569-80. 1996
    ..In contrast, T7 RNA polymerase can transcribe from its target promoter in all segments of the embryo. Thus, Pc-mediated repression blocks activated polymerase II transcription, but does not simply exclude all proteins...
  9. pmc Enhancer traps in the Drosophila bithorax complex mark parasegmental domains
    K McCall
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115
    Genetics 138:387-99. 1994
    ..Thus, the enhancer traps reveal parasegmental domains that are maintained by Polycomb-mediated repression. Such domains may be realized by parasegmental differences in chromatin structure...
  10. ncbi request reprint Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector
    E Bier
    Howard Hughes Medical Institute, San Francisco, California
    Genes Dev 3:1273-87. 1989
    ..This type of screen appears to be an effective way to find new loci that may play a role in the development of the Drosophila nervous system...
  11. ncbi request reprint Programmed cell death in the germline
    J S Baum
    Department of Biology, Boston University, 5 Cummington St, Boston, MA 02215, USA
    Semin Cell Dev Biol 16:245-59. 2005
    ..This review focuses on the cell death events that occur during gametogenesis in both vertebrates and invertebrates. It also examines the signals and machinery that initiate and carry out these germ cell deaths...
  12. ncbi request reprint Generating lineage-specific markers to study Drosophila development
    N Perrimon
    Department of Genetics, Harvard Medical School, Boston, MA 02115
    Dev Genet 12:238-52. 1991
    ..Insertion strains generated with P-elements that carry various sequences upstream of the lacZ gene exhibit an increased variety of expression patterns that can be used to study Drosophila development...