Andrew D McAinsh

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi Structure, function, and regulation of budding yeast kinetochores
    Andrew D McAinsh
    Department of Biology, and Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Annu Rev Cell Dev Biol 19:519-39. 2003
  2. pmc The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation
    Andrew D McAinsh
    Department of Biology, MIT, Cambridge, MA, USA
    EMBO J 25:4033-49. 2006
  3. pmc Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins
    Patrick Meraldi
    Department of Biology, Massachusetts Institute of Technology, Massachusetts Ave, Cambridge, MA 02139, USA
    Genome Biol 7:R23. 2006
  4. pmc Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes
    Peter De Wulf
    Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Genes Dev 17:2902-21. 2003
  5. pmc Bod1, a novel kinetochore protein required for chromosome biorientation
    Iain M Porter
    Division of Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, UK
    J Cell Biol 179:187-97. 2007
  6. pmc The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity
    Sarah E McClelland
    Chromosome Segregation Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey, UK
    EMBO J 26:5033-47. 2007
  7. ncbi Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing
    Rajat Roy
    Wellcome Trust Cancer Research UK Institute of Cancer and Developmental Biology, and Deparment of Zoology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK
    J Biol Chem 279:86-94. 2004
  8. pmc Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair
    Ali Jazayeri
    Wellcome Trust Cancer Research UK Gurdon Institute and Department of Zoology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, United Kingdom
    Proc Natl Acad Sci U S A 101:1644-9. 2004

Collaborators

  • Peter De Wulf
  • J J Blow
  • Patrick Meraldi
  • Sarah E McClelland
  • Iain M Porter
  • Stephen P Jackson
  • Rajat Roy
  • Ali Jazayeri
  • Christopher J Hunter
  • Guennadi A Khoudoli
  • Mukta Belwal
  • Satyarebala Borusu
  • Jennifer R Winter
  • Ana C Amaro
  • Jason R Swedlow
  • Jens S Andersen
  • Heidi M Feldmann
  • Bettina Meier

Detail Information

Publications8

  1. ncbi Structure, function, and regulation of budding yeast kinetochores
    Andrew D McAinsh
    Department of Biology, and Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Annu Rev Cell Dev Biol 19:519-39. 2003
    ..location of centromeres? What are the protein components of kinetochores, and how do they assemble a MT attachment site? How do MT attachments generate force? How do cells sense the state of attachment via the spindle assembly checkpoint?..
  2. pmc The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation
    Andrew D McAinsh
    Department of Biology, MIT, Cambridge, MA, USA
    EMBO J 25:4033-49. 2006
    ....
  3. pmc Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins
    Patrick Meraldi
    Department of Biology, Massachusetts Institute of Technology, Massachusetts Ave, Cambridge, MA 02139, USA
    Genome Biol 7:R23. 2006
    ....
  4. pmc Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes
    Peter De Wulf
    Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Genes Dev 17:2902-21. 2003
    ..In addition, we propose that the three complexes have different functions with respect to force generation and MT attachment...
  5. pmc Bod1, a novel kinetochore protein required for chromosome biorientation
    Iain M Porter
    Division of Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, UK
    J Cell Biol 179:187-97. 2007
    ..Therefore, Bod1 is a novel kinetochore protein that is required for the detection or resolution of syntelic attachments in mitotic spindles...
  6. pmc The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity
    Sarah E McClelland
    Chromosome Segregation Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey, UK
    EMBO J 26:5033-47. 2007
    ..Based on our results, we propose that the cooperative action of CENP-A NAC/CAD subunits and the KMN network drives efficient chromosome segregation and bipolar spindle assembly during mitosis...
  7. ncbi Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing
    Rajat Roy
    Wellcome Trust Cancer Research UK Institute of Cancer and Developmental Biology, and Deparment of Zoology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK
    J Biol Chem 279:86-94. 2004
    ..Taken together with other data, these findings indicate that the Yku80p-Sir4p interaction plays a vital role in the assembly of telomeric heterochromatin...
  8. pmc Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair
    Ali Jazayeri
    Wellcome Trust Cancer Research UK Gurdon Institute and Department of Zoology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, United Kingdom
    Proc Natl Acad Sci U S A 101:1644-9. 2004
    ..Taken together, these results define a role for the Sin3p/Rpd3p complex in the modulation of DNA repair...