Hideo Makimura

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Reduced growth hormone secretion in obesity is associated with smaller LDL and HDL particle size
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Clin Endocrinol (Oxf) 76:220-7. 2012
  2. pmc The effects of central adiposity on growth hormone (GH) response to GH-releasing hormone-arginine stimulation testing in men
    Hideo Makimura
    Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, LON 211, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 93:4254-60. 2008
  3. pmc Retinol-binding protein levels are increased in association with gonadotropin levels in healthy women
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Metabolism 58:479-87. 2009
  4. pmc Relationship of adiponectin to endogenous GH pulse secretion parameters in response to stimulation with a growth hormone releasing factor
    H Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States
    Growth Horm IGF Res 21:155-9. 2011
  5. pmc Reduced growth hormone secretion is associated with increased carotid intima-media thickness in obesity
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, LON 211, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 94:5131-8. 2009
  6. pmc Increased skeletal muscle phosphocreatine recovery after sub-maximal exercise is associated with increased carotid intima-media thickness
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Atherosclerosis 215:214-7. 2011
  7. pmc The association of growth hormone parameters with skeletal muscle phosphocreatine recovery in adult men
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, LON 211, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 96:817-23. 2011
  8. pmc The relationship between reduced testosterone, stimulated growth hormone secretion and increased carotid intima-media thickness in obese men
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School Boston Heart Foundation, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Endocrinol (Oxf) 73:622-9. 2010
  9. pmc Skeletal muscle phosphocreatine recovery after submaximal exercise in children and young and middle-aged adults
    Amy Fleischman
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 95:E69-74. 2010
  10. pmc TNF-alpha antagonism with etanercept decreases glucose and increases the proportion of high molecular weight adiponectin in obese subjects with features of the metabolic syndrome
    Takara L Stanley
    Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 96:E146-50. 2011

Collaborators

Detail Information

Publications19

  1. pmc Reduced growth hormone secretion in obesity is associated with smaller LDL and HDL particle size
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Clin Endocrinol (Oxf) 76:220-7. 2012
    ..We hypothesized that reduced GH secretion in obesity would be associated with a more atherogenic lipid profile including increased small dense LDL particles...
  2. pmc The effects of central adiposity on growth hormone (GH) response to GH-releasing hormone-arginine stimulation testing in men
    Hideo Makimura
    Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, LON 211, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 93:4254-60. 2008
    ..The relative contribution of central adiposity vs. weight on GH response to stimulation testing in obesity is not known...
  3. pmc Retinol-binding protein levels are increased in association with gonadotropin levels in healthy women
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Metabolism 58:479-87. 2009
    ..Retinol-binding protein was not associated with inflammatory markers or with carotid intima-media thickness. Therefore, RBP4 is higher in postmenopausal women and is associated with gonadotropin concentrations in healthy women...
  4. pmc Relationship of adiponectin to endogenous GH pulse secretion parameters in response to stimulation with a growth hormone releasing factor
    H Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States
    Growth Horm IGF Res 21:155-9. 2011
    ....
  5. pmc Reduced growth hormone secretion is associated with increased carotid intima-media thickness in obesity
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, LON 211, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 94:5131-8. 2009
    ..Obesity is associated with reduced GH...
  6. pmc Increased skeletal muscle phosphocreatine recovery after sub-maximal exercise is associated with increased carotid intima-media thickness
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Atherosclerosis 215:214-7. 2011
    ..The association between skeletal muscle mitochondrial function and CVD risk in healthy subjects is unknown...
  7. pmc The association of growth hormone parameters with skeletal muscle phosphocreatine recovery in adult men
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, LON 211, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 96:817-23. 2011
    ..Previous studies have suggested a relationship between GH and mitochondrial function. However, little is known about the relationship of specific GH indices and in vivo measures of mitochondrial function in humans...
  8. pmc The relationship between reduced testosterone, stimulated growth hormone secretion and increased carotid intima-media thickness in obese men
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School Boston Heart Foundation, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Endocrinol (Oxf) 73:622-9. 2010
    ....
  9. pmc Skeletal muscle phosphocreatine recovery after submaximal exercise in children and young and middle-aged adults
    Amy Fleischman
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 95:E69-74. 2010
    ..Elderly subjects have reduced mitochondrial function. However, it remains unclear whether the decline in mitochondrial function begins earlier in the life span...
  10. pmc TNF-alpha antagonism with etanercept decreases glucose and increases the proportion of high molecular weight adiponectin in obese subjects with features of the metabolic syndrome
    Takara L Stanley
    Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 96:E146-50. 2011
    ....
  11. pmc The effects of tesamorelin on phosphocreatine recovery in obese subjects with reduced GH
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit H M, C A M, M N F, S K G, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114
    J Clin Endocrinol Metab 99:338-43. 2014
    ..Few studies have assessed the relationship between GH and mitochondrial function...
  12. pmc Metabolic effects of a growth hormone-releasing factor in obese subjects with reduced growth hormone secretion: a randomized controlled trial
    Hideo Makimura
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 97:4769-79. 2012
    ..Obesity is associated with reduced GH secretion and increased cardiovascular disease risk...
  13. pmc Relationship between monocyte/macrophage activation marker soluble CD163 and insulin resistance in obese and normal-weight subjects
    Markella V Zanni
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Endocrinol (Oxf) 77:385-90. 2012
    ..The relationship of monocyte/macrophage activation to insulin resistance in obesity is unknown...
  14. pmc Effects of TNF-alpha antagonism on E-selectin in obese subjects with metabolic dysregulation
    Markella V Zanni
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Clin Endocrinol (Oxf) 73:48-54. 2010
    ....
  15. pmc Discordance of IGF-1 and GH stimulation testing for altered GH secretion in obesity
    Takara L Stanley
    Program in Nutritional Metabolism and Neuroendocrine Unit, Massachusetts General Hospital, Boston, MA 02114, United States Harvard Medical School, Boston, MA 02114, United States Pediatric Endocrine Unit, Massachusetts General Hospital, Boston, MA 02114, United States
    Growth Horm IGF Res 24:10-5. 2014
    ..To investigate the concordance/discordance of IGF-1 and peak stimulated GH in identifying subjects with reduced GH secretion and to determine the physiological significance of any discordance in obese subjects...
  16. pmc Effects of a growth hormone-releasing hormone analog on endogenous GH pulsatility and insulin sensitivity in healthy men
    Takara L Stanley
    Massachusetts General Hospital Program in Nutritional Metabolism, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 96:150-8. 2011
    ..The objective of this study was to determine the effects of a novel GHRH (GHRH(1-44)) analog, tesamorelin, on endogenous GH pulsatility and insulin sensitivity in healthy men...
  17. pmc Decreased respiratory quotient in relation to resting energy expenditure in HIV-infected and noninfected subjects
    Kathleen V Fitch
    Program in Nutritional Metabolism, Massachusetts General Hospital, Boston, MA 02114, USA
    Metabolism 58:608-15. 2009
    ..Overall r(2) was equal to 0.825 and P was less than .0001 for the model. These data suggest that alterations in substrate metabolism may contribute to increased REE in HIV-infected patients compared with control subjects...
  18. pmc Central diabetes insipidus: a previously unreported side effect of temozolomide
    Alexander T Faje
    MD, BUL 457, Neuroendocrine Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts 02114
    J Clin Endocrinol Metab 98:3926-31. 2013
    ..Using our institution's Research Patient Database Registry, we identified 3 additional potential cases of TMZ-induced diabetes insipidus among a group of 1545 patients treated with TMZ...
  19. pmc Effects of switching from lopinavir/ritonavir to atazanavir/ritonavir on muscle glucose uptake and visceral fat in HIV-infected patients
    Takara L Stanley
    Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA
    AIDS 23:1349-57. 2009
    ..To determine the effects of switching from lopinavir/ritonavir (LPV/r) to atazanavir/ritonavir (ATV/r) on muscle glucose uptake, glucose homeostasis, lipids, and body composition...