H D Madhani

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi request reprint The riddle of MAP kinase signaling specificity
    H D Madhani
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Trends Genet 14:151-5. 1998
  2. ncbi request reprint The control of filamentous differentiation and virulence in fungi
    H D Madhani
    Whitehead Institute for Biomedical Research, Nine Cambridge Center, MA 02142, USA
    Trends Cell Biol 8:348-53. 1998
  3. ncbi request reprint MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation
    H D Madhani
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Cell 91:673-84. 1997
  4. pmc Effectors of a developmental mitogen-activated protein kinase cascade revealed by expression signatures of signaling mutants
    H D Madhani
    Whitehead Massachusetts Institute of Technology, Center for Genome Research, Department of Biology, Cambridge, MA 02142, USA
    Proc Natl Acad Sci U S A 96:12530-5. 1999
  5. ncbi request reprint Combinatorial control required for the specificity of yeast MAPK signaling
    H D Madhani
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA
    Science 275:1314-7. 1997

Collaborators

Detail Information

Publications5

  1. ncbi request reprint The riddle of MAP kinase signaling specificity
    H D Madhani
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Trends Genet 14:151-5. 1998
    ..How are the myriad of inputs transduced accurately so that each evokes a specific response? One mechanism would be to have a distinct MAPK cascade for each signal; however, the situation appears to be more complicated...
  2. ncbi request reprint The control of filamentous differentiation and virulence in fungi
    H D Madhani
    Whitehead Institute for Biomedical Research, Nine Cambridge Center, MA 02142, USA
    Trends Cell Biol 8:348-53. 1998
    ..Strikingly, components used to signal sexual differentiation in the response to mating pheromones are often reutilized to regulate dimorphic development, suggesting an ancient link between these processes...
  3. ncbi request reprint MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation
    H D Madhani
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Cell 91:673-84. 1997
    ..In the absence of Fus3, there is erroneous crosstalk in which mating pheromone now activates filamentation-specific gene expression using the Kss1 MAPK...
  4. pmc Effectors of a developmental mitogen-activated protein kinase cascade revealed by expression signatures of signaling mutants
    H D Madhani
    Whitehead Massachusetts Institute of Technology, Center for Genome Research, Department of Biology, Cambridge, MA 02142, USA
    Proc Natl Acad Sci U S A 96:12530-5. 1999
    ..Thus, the Kss1 MAPK cascade programs development by coordinately modulating a cell adhesion factor, a secreted host-destroying activity, and a specialized subunit of the Cdc28 cyclin-dependent kinase...
  5. ncbi request reprint Combinatorial control required for the specificity of yeast MAPK signaling
    H D Madhani
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA
    Science 275:1314-7. 1997
    ..An FRE in the TEC1 promoter functions in a positive feedback loop required for pseudohyphal development...