A S Lundberg

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. pmc Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
    A S Lundberg
    The Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Mol Cell Biol 18:753-61. 1998
  2. ncbi request reprint Genes involved in senescence and immortalization
    A S Lundberg
    Whitehead Institute, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA
    Curr Opin Cell Biol 12:705-9. 2000
  3. ncbi request reprint Regulation of cyclin E transcription by E2Fs and retinoblastoma protein
    Y Geng
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Oncogene 12:1173-80. 1996

Collaborators

  • J M Roberts
  • Y Geng
  • E N Eaton
  • M Picon
  • C Sardet
  • R A Weinberg
  • A Gifford

Detail Information

Publications3

  1. pmc Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
    A S Lundberg
    The Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Mol Cell Biol 18:753-61. 1998
    ..Complete phosphorylation of pRb, inactivation of E2F binding, and activation of E2F transcription occur only after sequential action of at least two distinct G1 cyclin kinase complexes...
  2. ncbi request reprint Genes involved in senescence and immortalization
    A S Lundberg
    Whitehead Institute, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA
    Curr Opin Cell Biol 12:705-9. 2000
    ..Significant progress continues to be made in our understanding of cellular senescence and immortalization...
  3. ncbi request reprint Regulation of cyclin E transcription by E2Fs and retinoblastoma protein
    Y Geng
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Oncogene 12:1173-80. 1996
    ..The activity of this promoter can be regulated negatively by pRB. Our results suggest the operation of a positive-feedback loop in late G1 that functions to ensure continued cyclin E expression and pRB inactivation...