Jonathan Z Li

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Efficacy of short-course antibiotic regimens for community-acquired pneumonia: a meta-analysis
    Jonathan Z Li
    Department of Medicine, San Francisco VA Medical Center, University of California, San Francisco, CA 94143 0862, USA
    Am J Med 120:783-90. 2007
  2. pmc Ocular syphilis among HIV-infected individuals
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Clin Infect Dis 51:468-71. 2010
  3. pmc Clinical implications of HIV-1 minority variants
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin Infect Dis 56:1667-74. 2013
  4. pmc Prevalence and significance of HIV-1 drug resistance mutations among patients on antiretroviral therapy with detectable low-level viremia
    Jonathan Z Li
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Antimicrob Agents Chemother 56:5998-6000. 2012
  5. pmc Impact of minority nonnucleoside reverse transcriptase inhibitor resistance mutations on resistance genotype after virologic failure
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Infect Dis 207:893-7. 2013
  6. pmc Evaluation of HIV-1 ambiguous nucleotide frequency during antiretroviral treatment interruption
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, 65 Landsdowne Street, Room 435, Cambridge, MA, USA
    J Acquir Immune Defic Syndr 61:19-22. 2012
  7. pmc Characteristics and outcomes of initial virologic suppressors during analytic treatment interruption in a therapeutic HIV-1 gag vaccine trial
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 7:e34134. 2012
  8. pmc Relationship between minority nonnucleoside reverse transcriptase inhibitor resistance mutations, adherence, and the risk of virologic failure
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    AIDS 26:185-92. 2012
  9. pmc Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis
    Jonathan Z Li
    Section of Retroviral Therapeutics, Brigham and Women s Hospital, Harvard Medical School, Harvard University, Boston, Massachusetts 02139, USA
    JAMA 305:1327-35. 2011
  10. pmc Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial
    Jonathan Z Li
    Section of Retroviral Therapeutics, Brigham and Women s Hospital, Boston, Massachusetts 02139, USA
    J Infect Dis 203:976-83. 2011

Detail Information

Publications18

  1. ncbi request reprint Efficacy of short-course antibiotic regimens for community-acquired pneumonia: a meta-analysis
    Jonathan Z Li
    Department of Medicine, San Francisco VA Medical Center, University of California, San Francisco, CA 94143 0862, USA
    Am J Med 120:783-90. 2007
    ..The goal of this study is to systematically review randomized controlled trials comparing short-course and extended-course antibiotic regimens for community-acquired pneumonia...
  2. pmc Ocular syphilis among HIV-infected individuals
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Clin Infect Dis 51:468-71. 2010
    ..5 years. In patients with HIV infection, clinicians should be vigilant for ocular syphilis despite normal cerebrospinal fluid measures and for syphilis reinfection...
  3. pmc Clinical implications of HIV-1 minority variants
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin Infect Dis 56:1667-74. 2013
    ..Additional studies are needed to determine the optimal platform for clinical application of these new technologies and to provide guidance to clinicians on the type and frequency of clinically important HIV-1 minority variants...
  4. pmc Prevalence and significance of HIV-1 drug resistance mutations among patients on antiretroviral therapy with detectable low-level viremia
    Jonathan Z Li
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Antimicrob Agents Chemother 56:5998-6000. 2012
    ..Virologic failure followed 16% of LLV time points. Strategies for early intervention after LLV episodes should be further studied...
  5. pmc Impact of minority nonnucleoside reverse transcriptase inhibitor resistance mutations on resistance genotype after virologic failure
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Infect Dis 207:893-7. 2013
    ..NNRTI regimen choice and preexisting NNRTI-resistant minority variants were both associated with the probability and type of resistance mutations detected after virologic failure...
  6. pmc Evaluation of HIV-1 ambiguous nucleotide frequency during antiretroviral treatment interruption
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, 65 Landsdowne Street, Room 435, Cambridge, MA, USA
    J Acquir Immune Defic Syndr 61:19-22. 2012
    ..Increased HIV diversity during the ATI may represent a potentially higher barrier to success for a therapeutic as compared with a preventative vaccine targeting cell-mediated immunity...
  7. pmc Characteristics and outcomes of initial virologic suppressors during analytic treatment interruption in a therapeutic HIV-1 gag vaccine trial
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 7:e34134. 2012
    ..In the placebo-controlled trial ACTG A5197, a trend favoring viral suppression was seen in the HIV-1-infected subjects who received a recombinant Ad5 HIV-1 gag vaccine...
  8. pmc Relationship between minority nonnucleoside reverse transcriptase inhibitor resistance mutations, adherence, and the risk of virologic failure
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    AIDS 26:185-92. 2012
    ..To evaluate the risk of virologic failure conferred by suboptimal adherence to nonnucleoside reverse transcriptase inhibitors (NNRTIs) and minority NNRTI resistance mutations...
  9. pmc Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis
    Jonathan Z Li
    Section of Retroviral Therapeutics, Brigham and Women s Hospital, Harvard Medical School, Harvard University, Boston, Massachusetts 02139, USA
    JAMA 305:1327-35. 2011
    ....
  10. pmc Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial
    Jonathan Z Li
    Section of Retroviral Therapeutics, Brigham and Women s Hospital, Boston, Massachusetts 02139, USA
    J Infect Dis 203:976-83. 2011
    ..Human immunodeficiency virus type 1 (HIV-1) vaccines directed to the cell-mediated immune system could have a role in lowering the plasma HIV-1 RNA set point, which may reduce infectivity and delay disease progression...
  11. pmc Ocular syphilis among HIV-infected patients: a systematic analysis of the literature
    Joseph D Tucker
    Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, 55 Fruit Street, GRJ 504, Boston 02114, USA
    Sex Transm Infect 87:4-8. 2011
    ..Objective To examine the literature on HIV-infected patients and determine the results of treatment...
  12. pmc Low-level detection and quantitation of cellular HIV-1 DNA and 2-LTR circles using droplet digital PCR
    Timothy J Henrich
    Division of Infectious Diseases, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02119, USA
    J Virol Methods 186:68-72. 2012
    ..ddPCR is a promising novel technology for the study of HIV-1 reservoirs and persistence, but further optimization of this novel technology would enhance the detection of very low-level viral genetic targets...
  13. pmc Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation
    Timothy J Henrich
    Divison of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Infect Dis 207:1694-702. 2013
    ..The long-term impact of allogeneic hematopoietic stem cell transplantation (HSCT) on human immunodeficiency virus type 1 (HIV-1) reservoirs in patients receiving combination antiretroviral therapy (cART) is largely unknown...
  14. doi request reprint HIV-1 persistence in CD4+ T cells with stem cell-like properties
    Maria J Buzon
    1 Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA 2 Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA
    Nat Med 20:139-42. 2014
    ..Thus, HIV-1 may exploit the stem cell characteristics of cellular immune memory to promote long-term viral persistence. ..
  15. doi request reprint Incomplete adherence to antiretroviral therapy is associated with higher levels of residual HIV-1 viremia
    Jonathan Z Li
    aBrigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA bHôpital Saint Louis, Paris, France cCenter for Biostatistics in AIDS Research, Harvard School of Public Health dMassachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA Jonathan Z Li and Sebastien Gallien contributed equally to the writing of this article
    AIDS 28:181-6. 2014
    ..To evaluate the relationship between incomplete antiretroviral therapy (ART) adherence and levels of residual HIV-1 viremia...
  16. doi request reprint Predictors of pneumonia severity in HIV-infected adults admitted to an Urban public hospital
    Kara W Chew
    Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, California 90095, USA
    AIDS Patient Care STDS 25:273-7. 2011
    ..Lack of stable housing was not associated with worse outcomes. The PORT score may be a valid tool to predict mortality and need for hospital admission in HIV-infected patients with CAP...
  17. pmc Xenotropic murine leukemia virus-related virus prevalence in patients with chronic fatigue syndrome or chronic immunomodulatory conditions
    Timothy J Henrich
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Infect Dis 202:1478-81. 2010
    ..XMRV DNA was not detected in any participant samples. We found no association between XMRV and patients with chronic fatigue syndrome or chronic immunomodulatory conditions...
  18. ncbi request reprint HSV-1 encephalitis complicated by cerebral hemorrhage in an HIV-positive person
    Jonathan Z Li
    Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    AIDS Read 19:153-5. 2009
    ..He ultimately improved after surgical decompression, treatment with acyclovir, and a switch from a protease inhibitor-based antiretroviral regimen to one including an integrase inhibitor...