Research Topics
| Jonathan Z LiSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
Efficacy of short-course antibiotic regimens for community-acquired pneumonia: a meta-analysisJonathan Z Li
Department of Medicine, San Francisco VA Medical Center, University of California, San Francisco, CA 94143 0862, USA
Am J Med 120:783-90. 2007..The goal of this study is to systematically review randomized controlled trials comparing short-course and extended-course antibiotic regimens for community-acquired pneumonia...
Ocular syphilis among HIV-infected individualsJonathan Z Li
Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Clin Infect Dis 51:468-71. 2010..5 years. In patients with HIV infection, clinicians should be vigilant for ocular syphilis despite normal cerebrospinal fluid measures and for syphilis reinfection...
Prevalence and significance of HIV-1 drug resistance mutations among patients on antiretroviral therapy with detectable low-level viremiaJonathan Z Li
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Antimicrob Agents Chemother 56:5998-6000. 2012..Virologic failure followed 16% of LLV time points. Strategies for early intervention after LLV episodes should be further studied...
Impact of minority nonnucleoside reverse transcriptase inhibitor resistance mutations on resistance genotype after virologic failureJonathan Z Li
Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Infect Dis 207:893-7. 2013..NNRTI regimen choice and preexisting NNRTI-resistant minority variants were both associated with the probability and type of resistance mutations detected after virologic failure...
Evaluation of HIV-1 ambiguous nucleotide frequency during antiretroviral treatment interruptionJonathan Z Li
Division of Infectious Diseases, Brigham and Women s Hospital, 65 Landsdowne Street, Room 435, Cambridge, MA, USA
J Acquir Immune Defic Syndr 61:19-22. 2012..Increased HIV diversity during the ATI may represent a potentially higher barrier to success for a therapeutic as compared with a preventative vaccine targeting cell-mediated immunity...
Characteristics and outcomes of initial virologic suppressors during analytic treatment interruption in a therapeutic HIV-1 gag vaccine trialJonathan Z Li
Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
PLoS ONE 7:e34134. 2012..In the placebo-controlled trial ACTG A5197, a trend favoring viral suppression was seen in the HIV-1-infected subjects who received a recombinant Ad5 HIV-1 gag vaccine...
Relationship between minority nonnucleoside reverse transcriptase inhibitor resistance mutations, adherence, and the risk of virologic failureJonathan Z Li
Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
AIDS 26:185-92. 2012..To evaluate the risk of virologic failure conferred by suboptimal adherence to nonnucleoside reverse transcriptase inhibitors (NNRTIs) and minority NNRTI resistance mutations...
Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysisJonathan Z Li
Section of Retroviral Therapeutics, Brigham and Women s Hospital, Harvard Medical School, Harvard University, Boston, Massachusetts 02139, USA
JAMA 305:1327-35. 2011....
Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trialJonathan Z Li
Section of Retroviral Therapeutics, Brigham and Women s Hospital, Boston, Massachusetts 02139, USA
J Infect Dis 203:976-83. 2011..Human immunodeficiency virus type 1 (HIV-1) vaccines directed to the cell-mediated immune system could have a role in lowering the plasma HIV-1 RNA set point, which may reduce infectivity and delay disease progression...
Ocular syphilis among HIV-infected patients: a systematic analysis of the literatureJoseph D Tucker
Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, 55 Fruit Street, GRJ 504, Boston 02114, USA
Sex Transm Infect 87:4-8. 2011..Objective To examine the literature on HIV-infected patients and determine the results of treatment...
Low-level detection and quantitation of cellular HIV-1 DNA and 2-LTR circles using droplet digital PCRTimothy J Henrich
Division of Infectious Diseases, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02119, USA
J Virol Methods 186:68-72. 2012..ddPCR is a promising novel technology for the study of HIV-1 reservoirs and persistence, but further optimization of this novel technology would enhance the detection of very low-level viral genetic targets...
Predictors of pneumonia severity in HIV-infected adults admitted to an Urban public hospitalKara W Chew
Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, California 90095, USA
AIDS Patient Care STDS 25:273-7. 2011..Lack of stable housing was not associated with worse outcomes. The PORT score may be a valid tool to predict mortality and need for hospital admission in HIV-infected patients with CAP...
Xenotropic murine leukemia virus-related virus prevalence in patients with chronic fatigue syndrome or chronic immunomodulatory conditionsTimothy J Henrich
Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts, USA
J Infect Dis 202:1478-81. 2010..XMRV DNA was not detected in any participant samples. We found no association between XMRV and patients with chronic fatigue syndrome or chronic immunomodulatory conditions...
HSV-1 encephalitis complicated by cerebral hemorrhage in an HIV-positive personJonathan Z Li
Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
AIDS Read 19:153-5. 2009..He ultimately improved after surgical decompression, treatment with acyclovir, and a switch from a protease inhibitor-based antiretroviral regimen to one including an integrase inhibitor...
