Lynne L Levitsky

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc United States multicenter study of factors predicting the persistence of GH deficiency during the transition period between childhood and adulthood
    Charmian A Quigley
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Int J Pediatr Endocrinol 2013:6. 2013
  2. doi request reprint Adolescent obesity and bariatric surgery
    Lynne L Levitsky
    Pediatric Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Curr Opin Endocrinol Diabetes Obes 16:37-44. 2009
  3. ncbi request reprint Rathke's cleft cysts in children and adolescents: association with female puberty
    Paravee Katavetin
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, USA
    J Pediatr Endocrinol Metab 23:1175-80. 2010
  4. doi request reprint Recombinant human IGF-1 (insulin-like growth factor) therapy: where do we stand today?
    Bharti Balhara
    Pediatric Endocrine Unit, Massachusetts General Hospital for Children and Harvard Medical School, Room 539, 175 Cambridge Street, Boston, MA 02114, USA
    Indian J Pediatr 79:244-9. 2012
  5. ncbi request reprint Novel P2 promoter-derived HNF4alpha isoforms with different N-terminus generated by alternate exon insertion
    Jianmin Huang
    MassGeneral Hospital for Children, Harvard Medical School, Boston, Massachusetts 02114 2696, USA
    Exp Cell Res 315:1200-11. 2009
  6. doi request reprint Boosting native promoter activities with non-adjacent response-element multimers
    Jianmin Huang
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, MA 02114 2696, USA
    J Biotechnol 150:259-67. 2010
  7. ncbi request reprint Management of diabetic ketoacidosis in children and adolescents
    Nicole A Sherry
    Pediatric Endocrine Unit, Massachusetts General Hospital for Children, Harvard University, Boston, Massachusetts 02114, USA
    Paediatr Drugs 10:209-15. 2008
  8. ncbi request reprint Intermittent growth attenuation: is this a sign of craniopharyngioma?
    Madhusmita Misra
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, USA
    J Pediatr Endocrinol Metab 19:1033-8. 2006
  9. doi request reprint Clinical presentation of children with premature adrenarche
    Julia von Oettingen
    Massachusetts General Hospital for Children and Harvard Medical School, Boston, MA 02114, USA
    Clin Pediatr (Phila) 51:1140-9. 2012
  10. doi request reprint Expression of HNF4alpha variants in pancreatic islets and Ins-1 beta cells
    Jianmin Huang
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, MA 02114 2696, USA
    Diabetes Metab Res Rev 24:533-43. 2008

Collaborators

Detail Information

Publications20

  1. pmc United States multicenter study of factors predicting the persistence of GH deficiency during the transition period between childhood and adulthood
    Charmian A Quigley
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Int J Pediatr Endocrinol 2013:6. 2013
    ..Patients with history of idiopathic GHD (IGHD) pose the greatest management dilemma, as data regarding factors predictive of persistent GHD in this group are lacking...
  2. doi request reprint Adolescent obesity and bariatric surgery
    Lynne L Levitsky
    Pediatric Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Curr Opin Endocrinol Diabetes Obes 16:37-44. 2009
    ..Examines the effects of bariatric surgery on adolescent obesity...
  3. ncbi request reprint Rathke's cleft cysts in children and adolescents: association with female puberty
    Paravee Katavetin
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, USA
    J Pediatr Endocrinol Metab 23:1175-80. 2010
    ..Although estrogen and progesterone receptor immunostaining was negative in the cyst lining, estrogen receptor immunostaining was positive in adjacent pituitary cells. Further investigations regarding this issue are warranted...
  4. doi request reprint Recombinant human IGF-1 (insulin-like growth factor) therapy: where do we stand today?
    Bharti Balhara
    Pediatric Endocrine Unit, Massachusetts General Hospital for Children and Harvard Medical School, Room 539, 175 Cambridge Street, Boston, MA 02114, USA
    Indian J Pediatr 79:244-9. 2012
    ..The goal of this article is to review published data that describes the impact of IGF-1 therapy in treatment of short stature and other growth disorders...
  5. ncbi request reprint Novel P2 promoter-derived HNF4alpha isoforms with different N-terminus generated by alternate exon insertion
    Jianmin Huang
    MassGeneral Hospital for Children, Harvard Medical School, Boston, Massachusetts 02114 2696, USA
    Exp Cell Res 315:1200-11. 2009
    ..We recommend inclusion of exon 1E and nearby DNA sequences in screening for HNF4alpha mutations and polymorphisms in genetic analyses of MODY1 and T2DM...
  6. doi request reprint Boosting native promoter activities with non-adjacent response-element multimers
    Jianmin Huang
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, MA 02114 2696, USA
    J Biotechnol 150:259-67. 2010
    ..Augmentation of three promoters suggests that this approach is potentially applicable to other promoters for gene therapy and might obviate the need for viral promoters...
  7. ncbi request reprint Management of diabetic ketoacidosis in children and adolescents
    Nicole A Sherry
    Pediatric Endocrine Unit, Massachusetts General Hospital for Children, Harvard University, Boston, Massachusetts 02114, USA
    Paediatr Drugs 10:209-15. 2008
    ..Once DKA has resolved, subcutaneous insulin is initiated with careful consideration of its pharmacokinetics to avoid a period of insulin deficiency and metabolic decompensation...
  8. ncbi request reprint Intermittent growth attenuation: is this a sign of craniopharyngioma?
    Madhusmita Misra
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, USA
    J Pediatr Endocrinol Metab 19:1033-8. 2006
    ..These cases suggest the need for a low threshold to undertake hormonal evaluation of patients who present with a past history of growth attenuation...
  9. doi request reprint Clinical presentation of children with premature adrenarche
    Julia von Oettingen
    Massachusetts General Hospital for Children and Harvard Medical School, Boston, MA 02114, USA
    Clin Pediatr (Phila) 51:1140-9. 2012
    ..To describe the phenotype of premature adrenarche (PA) patients, elucidate historical and physical correlates, and distinguish PA from late-onset congenital adrenal hyperplasia (LOCAH)...
  10. doi request reprint Expression of HNF4alpha variants in pancreatic islets and Ins-1 beta cells
    Jianmin Huang
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, MA 02114 2696, USA
    Diabetes Metab Res Rev 24:533-43. 2008
    ..Because some variants lack the N-terminal activation function 1 (AF-1) and/or C-terminal inhibitory F domain, defining their tissue-specific regulation and function is important for understanding pancreatic beta cell behaviour...
  11. ncbi request reprint Predictors and growth consequences of central hypothyroidism in pediatric patients receiving recombinant human growth hormone
    Kara Wong
    Harvard Medical School, Boston, MA, USA
    J Pediatr Endocrinol Metab 23:451-61. 2010
    ..We hypothesized that children with GH deficiency (GHD) and greatest severity of GHD would be most likely to develop central hypothyroidism and decreased growth velocity (GV)...
  12. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 3-2005. A 14-year-old boy with recent slowing of growth and delayed puberty
    Esther J Israel
    Department of Pediatrics, the Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, USA
    N Engl J Med 352:393-403. 2005
  13. doi request reprint Polycystic ovary syndrome: clinical presentation in normal-weight compared with overweight adolescents
    Shilpa S McManus
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, Massachusetts 02114, USA
    Endocr Pract 19:471-8. 2013
    ..To characterize polycystic ovary syndrome (PCOS) in adolescents and determine whether a distinct clinical presentation differentiates normal-weight (NW) from overweight (OW) PCOS...
  14. doi request reprint Clinical monitoring guidelines for congenital hypothyroidism: laboratory outcome data in the first year of life
    Bharti Balhara
    Pediatric Endocrine Unit, Mass General Hospital for Children and Harvard Medical School, Boston, MA, USA
    J Pediatr 158:532-7. 2011
    ....
  15. ncbi request reprint Review: Pituitary adenomas in children and adolescents
    Paravee Katavetin
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, MA, USA
    J Pediatr Endocrinol Metab 23:427-31. 2010
    ..The high recurrence rate of Cushing disease in our series (46%) compared with adults treated surgically at this institution (7%) emphasizes the need for long-term follow-up...
  16. pmc Effect of body mass index on peak growth hormone response to provocative testing in children with short stature
    Takara L Stanley
    Pediatric Endocrine Unit, Massachusetts General Hospital for Children and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 94:4875-81. 2009
    ..Obesity is associated with decreased spontaneous and stimulated GH secretion, but the effect of body mass index (BMI) on results of GH stimulation testing in children with short stature is not known...
  17. doi request reprint Radioactive iodine for hyperthyroidism in children and adolescents: referral rate and response to treatment
    Shana McCormack
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Clin Endocrinol (Oxf) 71:884-91. 2009
    ..Our objective was to estimate treatment response and its predictors and describe current referral practices for (131)I therapy...
  18. ncbi request reprint Selective deletion of the Hnf1beta (MODY5) gene in beta-cells leads to altered gene expression and defective insulin release
    Li Wang
    Pediatric Endocrine Unit, MassGeneral Hospital for Children, Boston, Massachusetts 02114 2696, USA
    Endocrinology 145:3941-9. 2004
    ..These results indicate that HNF1beta is involved in regulating the beta-cell transcription factor network and is necessary for glucose sensing or glycolytic signaling...
  19. ncbi request reprint Developmental regulation of galactokinase in suckling mouse liver by the Egr-1 transcription factor
    Fang Yang
    Pediatric Endocrine Unit, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA 02114, USA
    Pediatr Res 55:822-9. 2004
    ..These data tie Egr-1 and galactokinase together in a developmentally regulated chain to prepare the neonate for suckling...
  20. ncbi request reprint Type 2 diabetes: an epidemic disease in childhood
    Tandy Aye
    Massachusetts General Hospital, Boston 02114, USA
    Curr Opin Pediatr 15:411-5. 2003
    ..However, the molecular mechanisms that promote diabetes in susceptible individuals, the best treatment plans, and methods of prevention of this disorder are not yet established...