T I Lee

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi request reprint Transcription of eukaryotic protein-coding genes
    T I Lee
    Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Annu Rev Genet 34:77-137. 2000
  2. ncbi request reprint Dissecting the regulatory circuitry of a eukaryotic genome
    F C Holstege
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Cell 95:717-28. 1998
  3. pmc Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme
    T I Lee
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Mol Cell Biol 18:4455-62. 1998
  4. pmc Remodeling of yeast genome expression in response to environmental changes
    H C Causton
    Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA
    Mol Biol Cell 12:323-37. 2001
  5. ncbi request reprint Regulation of gene expression by TBP-associated proteins
    T I Lee
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Genes Dev 12:1398-408. 1998

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Transcription of eukaryotic protein-coding genes
    T I Lee
    Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Annu Rev Genet 34:77-137. 2000
    ..We describe here the major advances in these areas, with particular emphasis on the modular complexes associated with RNA polymerase II that are targeted by activators and other regulators of mRNA biosynthesis...
  2. ncbi request reprint Dissecting the regulatory circuitry of a eukaryotic genome
    F C Holstege
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Cell 95:717-28. 1998
    ....
  3. pmc Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme
    T I Lee
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Mol Cell Biol 18:4455-62. 1998
    ..Taken together, these results suggest that transcription initiation involves a dynamic balance between activation mediated by specific components of the holoenzyme and repression by multiple TBP-associated regulators...
  4. pmc Remodeling of yeast genome expression in response to environmental changes
    H C Causton
    Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA
    Mol Biol Cell 12:323-37. 2001
    ..These results provide a global description of the transcriptional response to environmental change and extend our understanding of the role of activators in effecting this response...
  5. ncbi request reprint Regulation of gene expression by TBP-associated proteins
    T I Lee
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Genes Dev 12:1398-408. 1998