T I Lee

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi Transcription of eukaryotic protein-coding genes
    T I Lee
    Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Annu Rev Genet 34:77-137. 2000
  2. ncbi Dissecting the regulatory circuitry of a eukaryotic genome
    F C Holstege
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Cell 95:717-28. 1998
  3. ncbi Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme
    T I Lee
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Mol Cell Biol 18:4455-62. 1998
  4. ncbi Regulation of gene expression by TBP-associated proteins
    T I Lee
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Genes Dev 12:1398-408. 1998

Collaborators

Detail Information

Publications4

  1. ncbi Transcription of eukaryotic protein-coding genes
    T I Lee
    Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Annu Rev Genet 34:77-137. 2000
    ..We describe here the major advances in these areas, with particular emphasis on the modular complexes associated with RNA polymerase II that are targeted by activators and other regulators of mRNA biosynthesis...
  2. ncbi Dissecting the regulatory circuitry of a eukaryotic genome
    F C Holstege
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Cell 95:717-28. 1998
    ....
  3. ncbi Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme
    T I Lee
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Mol Cell Biol 18:4455-62. 1998
    ..Taken together, these results suggest that transcription initiation involves a dynamic balance between activation mediated by specific components of the holoenzyme and repression by multiple TBP-associated regulators...
  4. ncbi Regulation of gene expression by TBP-associated proteins
    T I Lee
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Genes Dev 12:1398-408. 1998