R L Kradin

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint Placebo response: a consideration of its role in therapeutics
    Richard L Kradin
    Departments of Medicine and Pathology, Center for Psychoanalytic Studies, Massachusetts General Hospital, Boston, 02114, USA
    Curr Psychiatry Rep 13:37-42. 2011
  2. doi request reprint Guiding the pulmonologist's hand: What they need to know about lung pathology and what is lost in translation
    Richard L Kradin
    Pulmonary and Critical Care Unit, Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Arch Pathol Lab Med 136:1528-32. 2012
  3. doi request reprint Malacoplakia of the tongue complicating the site of irradiation for squamous cell carcinoma with review of the literature
    Richard L Kradin
    Department of Pathology of the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Ann Diagn Pathol 16:214-8. 2012
  4. doi request reprint The pathology of pulmonary disorders due to Aspergillus spp
    Richard L Kradin
    Department of Pathology, Warren 253, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Pathol Lab Med 132:606-14. 2008
  5. ncbi request reprint Distinguishing benign mesothelial hyperplasia from neoplasia: a practical approach
    Richard L Kradin
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Semin Diagn Pathol 23:4-14. 2006
  6. ncbi request reprint Iatrogenic Trichuris suis infection in a patient with Crohn disease
    Richard L Kradin
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Pathol Lab Med 130:718-20. 2006
  7. ncbi request reprint Endothelial nitric oxide synthase expression in pulmonary capillary hemangiomatosis
    Richard Kradin
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Exp Mol Pathol 79:194-7. 2005
  8. ncbi request reprint The roots of empathy and aggression in analysis
    Richard Kradin
    Center for Psychoanalytical Studies, Massachusetts General Hospital, Boston 02114, USA
    J Anal Psychol 50:431-49. 2005
  9. ncbi request reprint The placebo response: its putative role as a functional salutogenic mechanism of the central nervous system
    Richard L Kradin
    Department of Medicine, Massachusetts General Hospital, Boston 02114, USA
    Perspect Biol Med 47:328-38. 2004
  10. ncbi request reprint IL-10 inhibits inflammation but does not affect fibrosis in the pulmonary response to bleomycin
    Richard L Kradin
    The Immunopathology and Pulmonary and Critical Care Units, Massachusetts General Hospital, Boston, MA 02114, USA
    Exp Mol Pathol 76:205-11. 2004

Collaborators

Detail Information

Publications40

  1. doi request reprint Placebo response: a consideration of its role in therapeutics
    Richard L Kradin
    Departments of Medicine and Pathology, Center for Psychoanalytic Studies, Massachusetts General Hospital, Boston, 02114, USA
    Curr Psychiatry Rep 13:37-42. 2011
    ....
  2. doi request reprint Guiding the pulmonologist's hand: What they need to know about lung pathology and what is lost in translation
    Richard L Kradin
    Pulmonary and Critical Care Unit, Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Arch Pathol Lab Med 136:1528-32. 2012
    ..This article, written by a pathologist who also practices pulmonology at a large, academic hospital, highlights his perspective on the important role of the pathologist in guiding the hand of the pulmonary clinician...
  3. doi request reprint Malacoplakia of the tongue complicating the site of irradiation for squamous cell carcinoma with review of the literature
    Richard L Kradin
    Department of Pathology of the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Ann Diagn Pathol 16:214-8. 2012
    ..The clinical features of this case, a review of previously reported cases, and a consideration of pathogenesis are presented...
  4. doi request reprint The pathology of pulmonary disorders due to Aspergillus spp
    Richard L Kradin
    Department of Pathology, Warren 253, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Pathol Lab Med 132:606-14. 2008
    ..This article reviews the spectrum of pulmonary disorders due to infection by Aspergillus spp, with emphasis on the clinical implications of diagnosis...
  5. ncbi request reprint Distinguishing benign mesothelial hyperplasia from neoplasia: a practical approach
    Richard L Kradin
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Semin Diagn Pathol 23:4-14. 2006
    ..Practical guidelines are offered that should reduce the risk of diagnostic error in this problematic area of surgical pathology...
  6. ncbi request reprint Iatrogenic Trichuris suis infection in a patient with Crohn disease
    Richard L Kradin
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Pathol Lab Med 130:718-20. 2006
    ..This report examines the morphology of the immature and adult T suis, the effects of this intervention on the immunophenotype of the bowel mucosa, and it also raises the possibility of persistent active infection in man...
  7. ncbi request reprint Endothelial nitric oxide synthase expression in pulmonary capillary hemangiomatosis
    Richard Kradin
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Exp Mol Pathol 79:194-7. 2005
    ..These findings suggest that NOS-III is specifically reduced in PCH when pulmonary arterial hypertensive remodeling is concomitantly present...
  8. ncbi request reprint The roots of empathy and aggression in analysis
    Richard Kradin
    Center for Psychoanalytical Studies, Massachusetts General Hospital, Boston 02114, USA
    J Anal Psychol 50:431-49. 2005
    ..Case material is examined to elucidate the benefits and limits of analytic aggression...
  9. ncbi request reprint The placebo response: its putative role as a functional salutogenic mechanism of the central nervous system
    Richard L Kradin
    Department of Medicine, Massachusetts General Hospital, Boston 02114, USA
    Perspect Biol Med 47:328-38. 2004
    ....
  10. ncbi request reprint IL-10 inhibits inflammation but does not affect fibrosis in the pulmonary response to bleomycin
    Richard L Kradin
    The Immunopathology and Pulmonary and Critical Care Units, Massachusetts General Hospital, Boston, MA 02114, USA
    Exp Mol Pathol 76:205-11. 2004
    ..The findings suggest an immunomodulatory role for IL-10 in the inflammatory response but not in the pulmonary fibrosis yielded by bleomycin...
  11. doi request reprint The placebo response: an attachment strategy that counteracts the effects of stress-related dysfunction
    Richard Kradin
    Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Perspect Biol Med 54:438-54. 2011
    ..A range of behaviors by caregivers that mimic those achieved during secure attachment are suggested to promote placebo responses...
  12. ncbi request reprint Epinephrine yields translocation of lymphocytes to the lung
    R Kradin
    Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Exp Mol Pathol 70:1-6. 2001
    ..Directed traffic of immune lymphocytes may be a feature of the adaptive immune response to stress at mucosal barrier surfaces...
  13. ncbi request reprint Pulmonary immunity to Listeria is enhanced by elimination of alveolar macrophages
    R L Kradin
    Departments of Pathology and Medicine, Massachusetts General Hospital, Boston, Massachusetts and Department of Histology, Amsterdam, The Netherlands
    Am J Respir Crit Care Med 159:1967-74. 1999
    ..We conclude that eliminating AM in vivo reduces local production of NO and promotes pulmonary cell-mediated immunity to HKL...
  14. ncbi request reprint Accumulation of macrophages with dendritic cell characteristics in the pulmonary response to Listeria
    R L Kradin
    Departments of Pathology and Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Respir Crit Care Med 161:535-42. 2000
    ..We conclude that a subset of RMA(dim) exudate macrophages shows phenotypic and functional evidence of dendritic cell differentiation...
  15. doi request reprint Case records of the Massachusetts General Hospital. Case 21-2008. An 11-month-old boy with fever and pulmonary infiltrates
    Jason B Harris
    Department of Pediatrics Pediatric Infectious Disease, Massachusetts General Hospital, USA
    N Engl J Med 359:178-87. 2008
  16. doi request reprint Shirt-sleeve or scanning magnification as an aid to the diagnosis of commonly encountered medical lung diseases
    Eugene J Mark
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02155, USA
    Arch Pathol Lab Med 132:539-47. 2008
    ..In our experience, this system also proves useful in arriving at some therapeutic decisions...
  17. pmc Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations
    David C Wilbur
    Department of Pathology, James Homer Wright Pathology Laboratories, Massachusetts General Hospital, and the Department of Pathology, Harvard Medical School, Boston, MA 02114, USA
    Arch Pathol Lab Med 133:1949-53. 2009
    ..Before implementation, technical issues, pathologist adaptability, and morphologic pitfalls must be well characterized...
  18. ncbi request reprint Inhibition of pulmonary fibrosis by the chemokine IP-10/CXCL10
    Andrew M Tager
    Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Building 149 8301, 13th Street, Charlestown, MA 02129, USA
    Am J Respir Cell Mol Biol 31:395-404. 2004
    ..Our findings suggest that interruption of fibroblast recruitment may represent a novel therapeutic strategy for pulmonary fibrosis, which could have applicability to a wide range of fibrotic illnesses...
  19. doi request reprint Idiopathic tracheal stenosis: a clinicopathologic study of 63 cases and comparison of the pathology with chondromalacia
    Eugene J Mark
    Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Surg Pathol 32:1138-43. 2008
    ..ITS is a rare disease and restricted to females. It may represent some form of fibromatosis. ITS can be distinguished histologically from CM in tracheal resection specimens in most cases...
  20. doi request reprint Immune cell subsets in necrotizing fasciitis: an immunohistochemical analysis
    A J Saenz
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Virchows Arch 455:87-92. 2009
    ..We conclude that immune lymphocytes and accessory immune cells are represented in substantial numbers in the early lesions of NF, and their presence supports current concepts with respect to the pathophysiology of this disorder...
  21. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-2004. A 52-year-old woman with recurrent episodes of atypical pneumonia
    Walter J O'Donnell
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, USA
    N Engl J Med 351:2741-9. 2004
  22. ncbi request reprint Case records of the Massachusetts General Hospital. Case 1-2006. A 64-year-old male lung-transplant recipient with fever, cough, hemoptysis, and abdominal pain
    Robert H Rubin
    Division of Infectious Disease, Brigham and Women s Hospital, Boston, USA
    N Engl J Med 354:180-7. 2006
  23. ncbi request reprint Bactericidal/permeability-increasing protein ameliorates acute lung injury in porcine endotoxemia
    T J VanderMeer
    Department of Surgery, Massachusetts General Hospital, Boston 02114
    J Appl Physiol 76:2006-14. 1994
    ..The salutory effects of BPI23 on acute lung injury in endotoxemic pigs may be mediated, at least in part, by inhibition of direct activation of phagocytes by LPS...
  24. ncbi request reprint Pulmonary "inflammatory myofibroblastic" tumors: a critical examination of the diagnostic category based on quantitative immunohistochemical analysis
    A B Farris
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Virchows Arch 450:585-90. 2007
    ..Although the multiplicity of terms previously applied to these lesions is cumbersome, retaining a descriptive phenomenological terminology may ultimately promote accurate elucidation of pathogenesis...
  25. ncbi request reprint Epinephrine promotes pulmonary angiitis: evidence for a beta1-adrenoreceptor-mediated mechanism
    Felipe A Jain
    Immunopathology and Pulmonary and Critical Care Units, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Physiol Lung Cell Mol Physiol 285:L232-9. 2003
    ..05) yielded by Epi, whereas all alpha/beta-AR blockers inhibited airway inflammation. We conclude that Epi-EP selectively promotes vascular inflammation in vivo via a beta1-receptor-mediated mechanism...
  26. doi request reprint Organizing pneumonia and pulmonary lymphatic architecture in diffuse alveolar damage
    Rajni V Mandal
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Hum Pathol 39:1234-8. 2008
    ..12). We conclude that lung biopsy histopathology and pulmonary lymphatic morphology may predict survival in acute respiratory distress syndrome...
  27. doi request reprint Nodular amiodarone lung disease
    Ruchira Ruangchira-urai
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 32:1654-60. 2008
    ..The necrotizing nature of the massed histiocytes in the absence of infection or obstruction suggests the correct etiologic diagnosis even when the history of administration of the drug is not available at initial review...
  28. ncbi request reprint Pathological recognition of diffuse malignant mesothelioma of the pleura: the significance of the historical perspective as regards this signal tumor
    Eugene J Mark
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
    Semin Diagn Pathol 23:25-34. 2006
    ....
  29. ncbi request reprint Case records of the Massachusetts General Hospital. Case 26-2007 - a 61-year-old man with recurrent fevers
    Gregg S Meyer
    Department of Medicine, Massachusetts General Hospital, USA
    N Engl J Med 357:807-16. 2007
  30. ncbi request reprint Megakaryocytes and platelet homeostasis in diffuse alveolar damage
    Rajni V Mandal
    Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
    Exp Mol Pathol 83:327-31. 2007
    ..The mechanisms of altered platelet homeostasis in DAD merit further investigation...
  31. ncbi request reprint Case records of the Massachusetts General Hospital. Case 29-2007. A 51-year-old man with gastric cancer and lung nodules
    Edward T Ryan
    Division of Infectious Disease, Massachusetts General Hospital, USA
    N Engl J Med 357:1239-46. 2007
  32. ncbi request reprint Hemorrhagic pulmonary oxalosis secondary to a noninvasive Aspergillus niger fungus ball
    Michael H A Roehrl
    Department of Pathology and Laboratory Medicine, James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Virchows Arch 451:1067-73. 2007
    ..Furthermore, non-necrotizing granulomatous lesions were identified in the lungs, liver, and spleen, consistent with sarcoidosis, and may have predisposed this patient to developing pulmonary aspergillomas...
  33. ncbi request reprint Case records of the Massachusetts General Hospital. Case 9-2006. A 35-year-old woman with recurrent right-upper-quadrant pain
    Rocio M Hurtado
    Infectious Disease Unit, Massachusetts General Hospital, USA
    N Engl J Med 354:1295-303. 2006
  34. doi request reprint Diffuse cellular and fibrosing interstitial pneumonitis with desquamative interstitial pneumonitis-like features associated with myeloid neoplasia
    Alton B Farris
    Pathology Service, Massachusetts General Hospital, Boston, MA, USA
    Am J Surg Pathol 33:1485-93. 2009
    ....
  35. ncbi request reprint Case records of the Massachusetts General Hospital. Case 27-2006. A 17-year-old boy with fever and lesions in the liver and spleen
    Stephen I Pelton
    Department of Pediatric Infectious Disease, Boston Medical Center, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    N Engl J Med 355:941-8. 2006
  36. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 9-2004. An 18-year-old man with respiratory symptoms and shock
    Julie L Gerberding
    Centers for Disease Control and Prevention, Atlanta, USA
    N Engl J Med 350:1236-47. 2004
  37. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 18-2002. A 48-year-old man with a cough and bloody sputum
    Richard L Kradin
    N Engl J Med 346:1892-9. 2002
  38. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 17-2002. A 55-year-old man with second-degree atrioventricular block and chest pain
    Roger J Hajjar
    N Engl J Med 346:1732-8. 2002
  39. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 1-2002. A 24-year-old woman with paresthesias and muscle cramps after a stay in Africa
    Thomas B Nutman
    Helminth Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA
    N Engl J Med 346:115-22. 2002
  40. ncbi request reprint Case records of the Massachusetts General Hospital. Case 5-2007. A 53-year-old man with a prosthetic aortic valve and recent onset of fatigue, dyspnea, weight loss, and sweats
    Didier Raoult
    Department of Clinical Microbiology, Unite des Rickettsies, Faculte de Medecine, Universite de la Mediterranee, Marseilles, France
    N Engl J Med 356:715-25. 2007