Research Topics
| Bruce A KoplanSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
Development and validation of a simple risk score to predict the need for permanent pacing after cardiac valve surgeryBruce A Koplan
Cardiac Arrhythmia Service Division of Cardiology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 41:795-801. 2003..The study objective was to develop and validate a simple risk score to predict postoperative permanent pacing (PPM) after valve surgery...
Ventricular tachycardia and sudden cardiac deathBruce A Koplan
Cardiac Arrhythmia Section, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02446, USA
Mayo Clin Proc 84:289-97. 2009..Catheter ablation may also be an option for appropriately selected patients with many forms of VT. This article discusses the etiologies and management of VT and its association with sudden death...
Heart failure decompensation and all-cause mortality in relation to percent biventricular pacing in patients with heart failure: is a goal of 100% biventricular pacing necessary?Bruce A Koplan
Brigham and Women s Hospital, Cardiovascular Division, Boston, MA 02115, USA
J Am Coll Cardiol 53:355-60. 2009..The goal of this analysis was to determine the appropriate biventricular pacing target in patients with heart failure (HF)...
A randomized trial of the effect of automated ventricular capture on device longevity and threshold measurement in pacemaker patientsBruce A Koplan
Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Pacing Clin Electrophysiol 31:1467-74. 2008..5 V above threshold. AC maintains this output and confirms capture on a beat-to-beat basis in bipolar and unipolar pacing and sensing...
Clinical and electrical performance of expanded polytetrafluoroethylene-covered defibrillator leads in comparison to traditional leadsBruce A Koplan
Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Pacing Clin Electrophysiol 31:47-55. 2008..In the ENDOTAK RELIANCE G defibrillation lead, coils are covered with expanded polytetrafluoroethylene (ePTFE) to prevent tissue ingrowth...
Survival in octogenarians receiving implantable defibrillatorsBruce A Koplan
Cardiac Arrhythmia Service Division of Cardiology, Brigham and Women s Hospital, Boston, MA 02115, USA
Am Heart J 152:714-9. 2006..Although clinical trials have expanded implantable defibrillator (ICD) indications, octogenarians have been poorly represented in these studies. Overall, survival in this subgroup is ill-defined...
Refractory ventricular tachycardia secondary to cardiac sarcoid: electrophysiologic characteristics, mapping, and ablationBruce A Koplan
Cardiac Arrhythmia Service, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Heart Rhythm 3:924-9. 2006..Cardiac sarcoidosis is a recognized cause of ventricular tachycardia (VT) and sudden death that has not been well studied...
Combined epicardial-endocardial approach to ablation of inappropriate sinus tachycardiaBruce A Koplan
Division of Cardiology and Cardiac Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Cardiovasc Electrophysiol 15:237-40. 2004..The anatomy and physiology of the sinus node is discussed, providing a basis for performing this procedure. This case provides an additional therapeutic option for a condition that often is difficult to manage...
Catheter ablation of ventricular tachycardia in nonischemic heart diseaseMichifumi Tokuda
Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
Circ Arrhythm Electrophysiol 5:992-1000. 2012..Conclusions- In patients with recurrent VT due to nonischemic heart disease, catheter ablation is often useful, although the outcome varies according to the nature of the underlying heart disease...
The long- and short-term impact of elevated body mass index on the risk of new atrial fibrillation the WHS (women's health study)Usha B Tedrow
Center for Arrhythmia Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Am Coll Cardiol 55:2319-27. 2010..The purpose of this study was to characterize the relationship between changes in body mass index (BMI) and incident atrial fibrillation (AF) in a large cohort of women...
Transcoronary ethanol ablation for recurrent ventricular tachycardia after failed catheter ablation: an updateMichifumi Tokuda
Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Circ Arrhythm Electrophysiol 4:889-96. 2011..After encouraging results with transcoronary ethanol ablation (TCEA), we began offering TCEA routinely when endocardial and epicardial RFCA failed or a deep intramural substrate was likely...
Incidence and predictors of major complications from contemporary catheter ablation to treat cardiac arrhythmiasMarius Bohnen
Cardiac Arrhythmia Service, Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Heart Rhythm 8:1661-6. 2011..Updated understanding of the risks of catheter ablation is important because techniques have evolved for procedures treating non-life-threatening as well as potentially lethal arrhythmias...
Ventricular arrhythmias and sudden cardiac deathRoy M John
Department of Medicine, Division of Cardiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Lancet 380:1520-9. 2012..Advances in understanding of genetic arrhythmia syndromes and in technology for mapping and ablation of ventricular arrhythmias, and enhanced algorithms in implantable devices for rhythm management, have contributed to improved outcomes...
Atrial arrhythmias after lung transplantation: epidemiology, mechanisms at electrophysiology study, and outcomesVincent Y See
Cardiac Arrhythmia Service, Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
Circ Arrhythm Electrophysiol 2:504-10. 2009..Atrial arrhythmias (AAs) including atrial fibrillation (AF) and atrial tachycardia (AT) are often observed after cardiothoracic surgery. Our aim was to evaluate the prevalence and mechanism of AAs after lung transplantation...
Percutaneous access of the epicardial space for mapping ventricular and supraventricular arrhythmias in patients with and without prior cardiac surgeryKurt C Roberts-Thomson
Department of Cardiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
J Cardiovasc Electrophysiol 21:406-11. 2010..There is a paucity of data on the success rates of achieving percutaneous epicardial access in different groups of patients...
Outcomes of cardiac perforation complicating catheter ablation of ventricular arrhythmiasMichifumi Tokuda
Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
Circ Arrhythm Electrophysiol 4:660-6. 2011..The study aims to investigate the incidence, management, and hospital outcomes of cardiac perforation complicating catheter ablation for ventricular arrhythmias...
Long-term follow-up in patients with presumptive Brugada syndrome treated with implanted defibrillatorsDaniel Steven
Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Cardiovasc Electrophysiol 22:1115-9. 2011..Risk stratification for patients with suspected Brugada syndrome (BS) remains difficult. Implantation of cardioverter-defibrillators (ICDs) in high-risk patients provides continuous long-term arrhythmia protection...
Effect of therapeutic INR on activated clotting times, heparin dosage, and bleeding risk during ablation of atrial fibrillationSandeep Gautam
Division of Cardiovascular Medicine, Brigham and Women s Hospital, 45 Francis St, Boston, MA 02115, USA
J Cardiovasc Electrophysiol 22:248-54. 2011..Heparin is administered during the procedure, but the effect of elevated INR on heparin requirements and target activation clotting times (ACT) ≥ 350 seconds during ablation is unknown...
Mortality and safety of catheter ablation for antiarrhythmic drug-refractory ventricular tachycardia in elderly patients with coronary artery diseaseKeiichi Inada
Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Heart Rhythm 7:740-4. 2010..Radiofrequency catheter ablation is useful for reducing VT therapy in patients with an implantable defibrillator. The utility of radiofrequency catheter ablation in the elderly is not well defined...
Resetting criteria during ventricular overdrive pacing successfully differentiate orthodromic reentrant tachycardia from atrioventricular nodal reentrant tachycardia despite interobserver disagreement concerning QRS fusionJonathan Z Rosman
Department of Cardiovascular Medicine at Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
Heart Rhythm 8:2-7. 2011..The end of the TZ is marked by the first beat with a stable QRS morphology but is a subjective assessment. Disagreement concerning this beat may change tachycardia diagnosis...
ICD lead proarrhythmia cured by lead extractionJoseph C Lee
Cardiac Arrhythmia Service, Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Heart Rhythm 6:613-8. 2009..However, clinical trials report higher rates of appropriate ICD therapies in implanted patients than untreated patient mortality rates would predict...
Coronary artery injury due to catheter ablation in adults: presentations and outcomesKurt C Roberts-Thomson
Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
Circulation 120:1465-73. 2009..Currently, only anecdotal information exists on the presentation and outcome of coronary arterial injury after ablation procedures...
Quality of life with atrial fibrillation: do the spouses suffer as much as the patients?Marius Bohnen
Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Pacing Clin Electrophysiol 34:804-9. 2011..Other chronic diseases are known to not only affect the patient but to also impact the QoL of persons living with them. Scant data exist on the QoL effect of AF in spouses/significant others (SOs)...
Ventricular tachycardia ablation: evolution of patients and procedures over 8 yearsFrederic Sacher
Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Circ Arrhythm Electrophysiol 1:153-61. 2008..We investigated the substrate, procedure, and outcome evolution of all patients referred for VT ablation during the past 8 years...
Influence of systolic and diastolic blood pressure on the risk of incident atrial fibrillation in womenDavid Conen
Center for Arrhythmia Prevention, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
Circulation 119:2146-52. 2009..The influence of systolic and diastolic blood pressure (BP) on incident atrial fibrillation (AF) is not well studied among initially healthy, middle-aged women...
Management of ventricular tachycardia complicating cardiac surgeryWilliam G Stevenson
Arrhythmia Service, Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Heart Rhythm 6:S66-9. 2009..The electrocardiographic characteristics of the arrhythmia and clinical characteristics of the patient are important considerations in the immediate and long-term management considerations...
Sustained ventricular tachycardia associated with corrective valve surgeryRobert E Eckart
Brigham and Women s Hospital and Harvard Medical School, Boston, Mass, USA
Circulation 116:2005-11. 2007..The causes of sustained monomorphic ventricular tachycardia (VT) after cardiac valve surgeries have not been studied extensively, although bundle-branch reentry has been reported...
ICD Implantation in Patients With Ischemic Left Ventricular DysfunctionJaydutt B Patel
Jaydutt B Patel, MD Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
Curr Treat Options Cardiovasc Med 11:3-9. 2009....
Catheter Ablation of Atrial Arrhythmias After Cardiac Transplantation: Findings at EP Study Utility of 3-D Mapping and OutcomesEyal Nof
Department of Medicine, Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Cardiovasc Electrophysiol 24:498-502. 2013..Management of atrial arrhythmias (AA) in orthotopic heart transplant (OHT) patients is challenging...
Cardiology patient page. Atrial flutterMelissa Boyer
Cardiovascular Division, Brigham and Women's Hospital, Boston, MA 02115, USA
Circulation 112:e334-6. 2005
Catheter ablation of ventricular tachycardia after repair of congenital heart disease: electroanatomic identification of the critical right ventricular isthmusKatja Zeppenfeld
Department of Cardiology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Circulation 116:2241-52. 2007..Insights into the relation between anatomic isthmuses identified by delineating unexcitable tissue using substrate mapping techniques and critical reentry circuit isthmuses might facilitate ablation...
