Research Topics
| Konstantinos T KonstantinidisSummaryAffiliation: Massachusetts Institute of Technology Country: USA Publications
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Detail Information
Publications
The bacterial species definition in the genomic eraKonstantinos T Konstantinidis
Center for Microbial Ecology, Michigan State University, East Lansing, MI 48824, USA
Philos Trans R Soc Lond B Biol Sci 361:1929-40. 2006....
Toward a more robust assessment of intraspecies diversity, using fewer genetic markersKonstantinos T Konstantinidis
Center for Microbial Ecology, Michigan State University, East Lansing, Michigan, USA
Appl Environ Microbiol 72:7286-93. 2006..Our results are reproducible within the Salmonella, Burkholderia, and Shewanella groups and therefore are expected to have general applicability for microevolution studies, including metagenomic surveys...
Towards a genome-based taxonomy for prokaryotesKonstantinos T Konstantinidis
Center for Microbial Ecology, Michigan State University, East Lansing, Michigan 48824-1325, USA
J Bacteriol 187:6258-64. 2005..78 > R2 > 0.69 for the protein-coding genes versus R2 = 0.84 for the rRNA genes). The AAI approach outlined here could contribute significantly to a genome-based taxonomy for all microbial organisms...
Identification of potential therapeutic targets for Burkholderia cenocepacia by comparative transcriptomicsDeborah R Yoder-Himes
Center for Microbial Ecology, Michigan State University, East Lansing, Michigan, United States of America
PLoS ONE 5:e8724. 2010..The identification of virulence factors and potential therapeutic targets has been hampered by the genomic diversity within the species as many factors are not shared among the pathogenic members of the species...
Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatilityPatrick S G Chain
Center for Microbial Ecology, Michigan State University, East Lansing, MI 48824, USA
Proc Natl Acad Sci U S A 103:15280-7. 2006....
DNA-DNA hybridization values and their relationship to whole-genome sequence similaritiesJohan Goris
Center for Microbial Ecology, Michigan State University, East Lansing, MI 48824, USA
Int J Syst Evol Microbiol 57:81-91. 2007..It is concluded that ANI can accurately replace DDH values for strains for which genome sequences are available...
Genomic insights that advance the species definition for prokaryotesKonstantinos T Konstantinidis
Center for Microbial Ecology, and Department of Crop and Soil Sciences, Michigan State University, East Lansing, MI 48824, USA
Proc Natl Acad Sci U S A 102:2567-72. 2005....
Trends between gene content and genome size in prokaryotic species with larger genomesKonstantinos T Konstantinidis
Center for Microbial Ecology and Departments of Crop and Soil Sciences, Michigan State University, East Lansing, MI 48824-1325, USA
Proc Natl Acad Sci U S A 101:3160-5. 2004..These trends suggest that larger genome-sized species may dominate in environments where resources are scarce but diverse and where there is little penalty for slow growth, such as soil...
Prokaryotic taxonomy and phylogeny in the genomic era: advancements and challenges aheadKonstantinos T Konstantinidis
School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, GA, USA
Curr Opin Microbiol 10:504-9. 2007..Only then can the promise for a superior genome-based taxonomy materialize...
Predicting sigma28 promoters in eleven Shewanella genomesWenjie Song
Department of Geography and Environmental Engineering, The Johns Hopkins University, 3400 N Charles Street, Baltimore, MD, USA
FEMS Microbiol Lett 283:223-30. 2008..This dual-pronged approach identified several genes that have sigma(28) promoters and that may be involved with motility or chemotaxis in Shewanella...
Phylogenetic analyses of ribosomal DNA-containing bacterioplankton genome fragments from a 4000 m vertical profile in the North Pacific Subtropical GyreVinh D Pham
Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Environ Microbiol 10:2313-30. 2008....
Genomic patterns of recombination, clonal divergence and environment in marine microbial populationsKonstantinos T Konstantinidis
Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
ISME J 2:1052-65. 2008....
Global profiling of Shewanella oneidensis MR-1: expression of hypothetical genes and improved functional annotationsEugene Kolker
BIATECH, 19310 North Creek Parkway, Suite 115, Bothell, WA 98011, USA
Proc Natl Acad Sci U S A 102:2099-104. 2005..We propose that this integrative approach offers a valuable means to undertake the enormous challenge of characterizing the rapidly growing number of hypothetical proteins with each newly sequenced genome...
Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum symbiosumSteven J Hallam
Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Proc Natl Acad Sci U S A 103:18296-301. 2006..In total, the C. symbiosum genome was remarkably distinct from those of other known Archaea and shared many core metabolic features in common with its free-living planktonic relatives...
