- The psychophysics of visual motion and global form processing in autism
McGovern Institute for Brain Research, Cambridge, MA 02139, USA
Brain 133:599-610. 2010
..These results do not support a general dorsal stream dysfunction in adolescents with autism but provide evidence of a more complex impairment in higher-level dynamic attentional processes...
- Amygdala dysfunction in men with the fragile X premutation
Medical Investigation of Neurodevelopmental Disorders MIND Institute, University of California Davis, Medical Center, Sacramento, CA 95817, USA
Brain 130:404-16. 2007
..The aetiology for this dysfunction may be elevated FMR1 mRNA or reduced FMR1 protein that occurs in carriers with higher premutation CGG repeat alleles...
- Anatomical connectivity patterns predict face selectivity in the fusiform gyrus
Zeynep M Saygin
Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
Nat Neurosci 15:321-7. 2012
..Additionally, we identified cortical regions whose connectivity was highly influential in predicting face selectivity within the fusiform, suggesting a possible mechanistic architecture underlying face processing in humans...
- Investigation of amygdala volume in men with the fragile X premutation
Center for Mind and Brain, University of California, 202 Cousteau Place, Suite 250, Davis, CA 95618, USA
Brain Imaging Behav 5:285-94. 2011
..However, a significant negative correlation between amygdala volume and CGG was found in the lower range of CGG repeat expansions, but not in the higher range of CGG repeat expansions...
- Psychological symptoms correlate with reduced hippocampal volume in fragile X premutation carriers
P E Adams
M I N D Institute, University of California, Davis Health System, Sacramento, California, USA
Am J Med Genet B Neuropsychiatr Genet 153:775-85. 2010
..Though the presentation of FXTAS symptoms is less common in females, anxiety-related problems are common both prior to and after the onset of FXTAS, and may be related to hippocampal changes...
- Volumetric brain changes in females with fragile X-associated tremor/ataxia syndrome (FXTAS)
J S Adams
M I N D Institute, University of California, Davis, CA, USA
Neurology 69:851-9. 2007
..Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder occurring in male and rare female carriers of a premutation expansion (55 to 200 CGG repeats) of the fragile X mental retardation 1 (FMR1) gene...
- Brief report: aggression and stereotypic behavior in males with fragile X syndrome--moderating secondary genes in a "single gene" disorder
Medical Investigation of Neurodevelopmental Disorders MIND Institute, University of California Davis, Medical Center, 2825 50th Street, Sacramento, CA 95817, USA
J Autism Dev Disord 38:184-9. 2008
..This preliminary study prompts consideration of secondary genes that may modify behavioral phenotype expression in neurodevelopmental disorders, even those with a single gene etiology such as FXS...
- Independent coding of object motion and position revealed by distinct contingent aftereffects
Paul F Bulakowski
The Department of Psychology, University of California, Davis, CA 95616, USA
Vision Res 47:810-7. 2007
..The dissociation between perceived motion and position of the same test pattern, following identical adaptation, demonstrates that distinguishable neural populations code for these object properties...
- Face identity recognition in autism spectrum disorders: a review of behavioral studies
Department of Brain and Cognitive Science and McGovern Institute for Brain Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, USA
Neurosci Biobehav Rev 36:1060-84. 2012
..Although some evidence suggests that this deficit may be specific to faces, further evidence on this question is necessary...
- Cross-category adaptation reveals tight coupling of face and body perception
Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
J Neurophysiol 104:581-3. 2010
..Here we report on a recent study by Ghuman and colleagues and other behavioral and neuroimaging investigations that, taken together, provide compelling evidence for a tight coupling of face and body perception...
- Neural correlates of coherent and biological motion perception in autism
Medical Investigation of Neurodevelopmental Disorders MIND Institute, University of California Davis, USA
Dev Sci 14:1075-88. 2011
..Notably, however, activity in DLPFC was negatively related to autism symptom severity. These results suggest that impairments in higher-order social or attentional networks may underlie visual motion deficits observed in autism...