Vijaya B Kolachalama

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi request reprint Predictive haemodynamics in a one-dimensional human carotid artery bifurcation. Part I: Application to stent design
    Vijaya B Kolachalama
    Biomedical Engineering Center, Harvard MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA
    IEEE Trans Biomed Eng 54:802-12. 2007
  2. pmc Mining data from hemodynamic simulations via Bayesian emulation
    Vijaya B Kolachalama
    Biomedical Engineering Center, Harvard MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA
    Biomed Eng Online 6:47. 2007
  3. pmc Luminal flow amplifies stent-based drug deposition in arterial bifurcations
    Vijaya B Kolachalama
    Biomedical Engineering Center, Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
    PLoS ONE 4:e8105. 2009
  4. pmc Luminal flow patterns dictate arterial drug deposition in stent-based delivery
    Vijaya B Kolachalama
    Biomedical Engineering Center, Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA
    J Control Release 133:24-30. 2009
  5. doi request reprint Predictive haemodynamics in a one-dimensional human carotid artery bifurcation. Part II: Application to graft design
    Vijaya B Kolachalama
    Biomedical Engineering Center, Harvard MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA
    IEEE Trans Biomed Eng 55:1176-84. 2008
  6. pmc Mechanisms of tissue uptake and retention in zotarolimus-coated balloon therapy
    Vijaya B Kolachalama
    Harvard MIT Division of Health Sciences and Technology, Cambridge, MA, USA
    Circulation 127:2047-55. 2013
  7. ncbi request reprint Extent of flow recirculation governs expression of atherosclerotic and thrombotic biomarkers in arterial bifurcations
    Jordi Martorell
    Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA Department of Chemical Engineering, IQS School of Engineering, URL, Via Augusta 390, 08017 Barcelona, Spain
    Cardiovasc Res 103:37-46. 2014
  8. pmc Lesion complexity determines arterial drug distribution after local drug delivery
    Abraham R Tzafriri
    Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Control Release 142:332-8. 2010
  9. pmc Impact of flow pulsatility on arterial drug distribution in stent-based therapy
    Caroline C O'Brien
    Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia
    J Control Release 168:115-24. 2013
  10. pmc Performance and scaling effects in a multilayer microfluidic extracorporeal lung oxygenation device
    Tatiana Kniazeva
    Draper Laboratory, 555 Technology Square, Cambridge, MA, USA
    Lab Chip 12:1686-95. 2012

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Predictive haemodynamics in a one-dimensional human carotid artery bifurcation. Part I: Application to stent design
    Vijaya B Kolachalama
    Biomedical Engineering Center, Harvard MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA
    IEEE Trans Biomed Eng 54:802-12. 2007
    ..In particular, it is found that localized pressure peaks do not depend on the length of a stent. Finally, we demonstrate how these metrics may be applied to cost-effectively predict the benefit of stenting...
  2. pmc Mining data from hemodynamic simulations via Bayesian emulation
    Vijaya B Kolachalama
    Biomedical Engineering Center, Harvard MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA
    Biomed Eng Online 6:47. 2007
    ..To ensure realistic prediction of cardiovascular flows, there is a need for efficient numerical methods that can systematically account for geometric uncertainty...
  3. pmc Luminal flow amplifies stent-based drug deposition in arterial bifurcations
    Vijaya B Kolachalama
    Biomedical Engineering Center, Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
    PLoS ONE 4:e8105. 2009
    ....
  4. pmc Luminal flow patterns dictate arterial drug deposition in stent-based delivery
    Vijaya B Kolachalama
    Biomedical Engineering Center, Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA
    J Control Release 133:24-30. 2009
    ..Coronary drug-eluting stents should be appropriately considered where luminal flow, strut design and pulsatility have direct effects on tissue drug uptake after local delivery...
  5. doi request reprint Predictive haemodynamics in a one-dimensional human carotid artery bifurcation. Part II: Application to graft design
    Vijaya B Kolachalama
    Biomedical Engineering Center, Harvard MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA
    IEEE Trans Biomed Eng 55:1176-84. 2008
    ..5%, 80%, 85%, and 90% stenosis in the ICA, respectively...
  6. pmc Mechanisms of tissue uptake and retention in zotarolimus-coated balloon therapy
    Vijaya B Kolachalama
    Harvard MIT Division of Health Sciences and Technology, Cambridge, MA, USA
    Circulation 127:2047-55. 2013
    ..Most systems to date have used paclitaxel, touting its propensity to associate with various excipients that can optimize its transfer and retention. We examined zotarolimus pharmacokinetics...
  7. ncbi request reprint Extent of flow recirculation governs expression of atherosclerotic and thrombotic biomarkers in arterial bifurcations
    Jordi Martorell
    Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA Department of Chemical Engineering, IQS School of Engineering, URL, Via Augusta 390, 08017 Barcelona, Spain
    Cardiovasc Res 103:37-46. 2014
    ....
  8. pmc Lesion complexity determines arterial drug distribution after local drug delivery
    Abraham R Tzafriri
    Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Control Release 142:332-8. 2010
    ....
  9. pmc Impact of flow pulsatility on arterial drug distribution in stent-based therapy
    Caroline C O'Brien
    Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia
    J Control Release 168:115-24. 2013
    ..Our results indicate that factors governing pulsatile luminal flow on arterial drug deposition should be carefully considered in conjunction with device deployment settings for better utilization of drug-eluting stent therapy...
  10. pmc Performance and scaling effects in a multilayer microfluidic extracorporeal lung oxygenation device
    Tatiana Kniazeva
    Draper Laboratory, 555 Technology Square, Cambridge, MA, USA
    Lab Chip 12:1686-95. 2012
    ..These results contribute to our understanding of the complexity involved in designing three-dimensional microfluidic oxygenators for clinical applications...
  11. pmc Stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings
    Kumaran Kolandaivelu
    77 Massachusetts Ave, Cambridge, MA 02139, USA
    Circulation 123:1400-9. 2011
    ..Stent thrombosis is a lethal complication of endovascular intervention. Concern has been raised about the inherent risk associated with specific stent designs and drug-eluting coatings, yet clinical and animal support is equivocal...