Michael Klompas

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Does this patient have ventilator-associated pneumonia?
    Michael Klompas
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    JAMA 297:1583-93. 2007
  2. ncbi request reprint Does this patient have an acute thoracic aortic dissection?
    Michael Klompas
    Department of Medicine, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    JAMA 287:2262-72. 2002
  3. doi request reprint Development of an algorithm for surveillance of ventilator-associated pneumonia with electronic data and comparison of algorithm results with clinician diagnoses
    Michael Klompas
    Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, Massachusetts, USA
    Infect Control Hosp Epidemiol 29:31-7. 2008
  4. pmc Automated detection and classification of type 1 versus type 2 diabetes using electronic health record data
    Michael Klompas
    Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA
    Diabetes Care 36:914-21. 2013
  5. doi request reprint Objective surveillance definitions for ventilator-associated pneumonia
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Crit Care Med 40:3154-61. 2012
  6. doi request reprint Integrating clinical practice and public health surveillance using electronic medical record systems
    Michael Klompas
    Harvard Medical School and Harvard Pilgrim Health Care Institute, Department of Population Medicine, Boston, Massachusetts 02215, USA
    Am J Prev Med 42:S154-62. 2012
  7. pmc Integrating clinical practice and public health surveillance using electronic medical record systems
    Michael Klompas
    Harvard Medical School, and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Am J Public Health 102:S325-32. 2012
  8. doi request reprint Variability in mean duration of mechanical ventilation among community hospitals
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Infect Control Hosp Epidemiol 33:635-7. 2012
  9. doi request reprint Is a ventilator-associated pneumonia rate of zero really possible?
    Michael Klompas
    Infection Control Department, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Curr Opin Infect Dis 25:176-82. 2012
  10. doi request reprint Rapid and reproducible surveillance for ventilator-associated pneumonia
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts 02215, USA
    Clin Infect Dis 54:370-7. 2012

Detail Information

Publications31

  1. ncbi request reprint Does this patient have ventilator-associated pneumonia?
    Michael Klompas
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    JAMA 297:1583-93. 2007
    ..Ventilator-associated pneumonia (VAP) is a common and serious nosocomial infection. Accurate, timely diagnosis enables affected patients to receive appropriate therapy and avoids mistreatment of patients having other conditions...
  2. ncbi request reprint Does this patient have an acute thoracic aortic dissection?
    Michael Klompas
    Department of Medicine, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    JAMA 287:2262-72. 2002
    ..The diagnosis of acute thoracic aortic dissection is difficult to make and often missed...
  3. doi request reprint Development of an algorithm for surveillance of ventilator-associated pneumonia with electronic data and comparison of algorithm results with clinician diagnoses
    Michael Klompas
    Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, Massachusetts, USA
    Infect Control Hosp Epidemiol 29:31-7. 2008
    ..We sought to improve the efficiency and objectivity of VAP surveillance by adapting the CDC criteria to make them amenable to evaluation with electronic data...
  4. pmc Automated detection and classification of type 1 versus type 2 diabetes using electronic health record data
    Michael Klompas
    Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA
    Diabetes Care 36:914-21. 2013
    ..To create surveillance algorithms to detect diabetes and classify type 1 versus type 2 diabetes using structured electronic health record (EHR) data...
  5. doi request reprint Objective surveillance definitions for ventilator-associated pneumonia
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Crit Care Med 40:3154-61. 2012
    ..We explored the feasibility of creating objective surveillance definitions for ventilator-associated pneumonia...
  6. doi request reprint Integrating clinical practice and public health surveillance using electronic medical record systems
    Michael Klompas
    Harvard Medical School and Harvard Pilgrim Health Care Institute, Department of Population Medicine, Boston, Massachusetts 02215, USA
    Am J Prev Med 42:S154-62. 2012
    ..The ESP platform provides live, automated surveillance for notifiable diseases, influenza-like illness, and diabetes prevalence, care, and complications. Results are automatically transmitted to state health departments...
  7. pmc Integrating clinical practice and public health surveillance using electronic medical record systems
    Michael Klompas
    Harvard Medical School, and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Am J Public Health 102:S325-32. 2012
    ..The ESP platform provides live, automated surveillance for notifiable diseases, influenza-like illness, and diabetes prevalence, care, and complications. Results are automatically transmitted to state health departments...
  8. doi request reprint Variability in mean duration of mechanical ventilation among community hospitals
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Infect Control Hosp Epidemiol 33:635-7. 2012
    ..Mean ventilator-days per patient varied 4-fold within a network of community hospitals despite adjusting for multiple patient and hospital factors. Further assessment of this metric is warranted...
  9. doi request reprint Is a ventilator-associated pneumonia rate of zero really possible?
    Michael Klompas
    Infection Control Department, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Curr Opin Infect Dis 25:176-82. 2012
    ..This article explores the significance of very low VAP rates, reviews differences in surveillance and clinical rates, proposes reasons for their discrepancies, and suggests possible objective alternatives for surveillance...
  10. doi request reprint Rapid and reproducible surveillance for ventilator-associated pneumonia
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts 02215, USA
    Clin Infect Dis 54:370-7. 2012
    ..The complexity and subjectivity of ventilator-associated pneumonia (VAP) surveillance limit its value in assessing and comparing quality of care for ventilated patients. A simpler, more quantitative VAP definition may increase utility...
  11. pmc Multicenter evaluation of a novel surveillance paradigm for complications of mechanical ventilation
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, United States of America
    PLoS ONE 6:e18062. 2011
    ..We therefore evaluated a novel surveillance paradigm for ventilator-associated complications (VAC) defined by sustained increases in patients' ventilator settings after a period of stable or decreasing support...
  12. pmc Herpes zoster and postherpetic neuralgia surveillance using structured electronic data
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Mayo Clin Proc 86:1146-53. 2011
    ..To develop electronic algorithms for rapid, automated surveillance for herpes zoster and postherpetic neuralgia (PHN) using codified electronic health data...
  13. doi request reprint Prevention of ventilator-associated pneumonia
    Michael Klompas
    Infection Control Department, Brigham and Women s Hospital, Boston, MA 02115, USA
    Expert Rev Anti Infect Ther 8:791-800. 2010
    ..This article will review selected VAP prevention methods using this framework and advocate for the development of a new surveillance definition that will more reliably predict patient outcomes...
  14. doi request reprint Interobserver variability in ventilator-associated pneumonia surveillance
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02245, USA
    Am J Infect Control 38:237-9. 2010
    ..Infection control personnel labelled between 11 and 20 patients with VAP (kappa = 0.40). The physician diagnosed 7 cases. Interobserver variability in the assessment of ventilator-associated pneumonia is high...
  15. doi request reprint Risk of misleading ventilator-associated pneumonia rates with use of standard clinical and microbiological criteria
    Michael Klompas
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Clin Infect Dis 46:1443-6. 2008
    ..The addition of microbiological criteria to standard clinical criteria decreased the range of apparent VAP to 3.5%-15.5%. These wide margins of variability suggest that VAP rates are an unreliable measure of quality of care...
  16. pmc Automated identification of acute hepatitis B using electronic medical record data to facilitate public health surveillance
    Michael Klompas
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, United States of America
    PLoS ONE 3:e2626. 2008
    ..We describe the development and implementation of an algorithm for prospective surveillance of patients with acute hepatitis B using electronic medical record data...
  17. pmc The paradox of ventilator-associated pneumonia prevention measures
    Michael Klompas
    Infection Control Department, Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Crit Care 13:315. 2009
    ..The paradox makes changes in VAP rates alone an unreliable measure of whether VAP prevention measures are truly beneficial to patients and behooves us to measure their impact on patient outcomes before advocating their adoption...
  18. doi request reprint Developing a new, national approach to surveillance for ventilator-associated events
    Shelley S Magill
    Shelley S Magill, Scott Fridkin, Alice Guh, and Teresa Horan are from the Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia Michael Klompas is from the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute and the Infection Control Department, Brigham and Women s Hospital, Boston, Massachusetts and represents the Society for Healthcare Epidemiology of America, Arlington, Virginia Robert Balk is from the Division of Pulmonary and Critical Care Medicine, Rush University School of Medicine, Chicago, Illinois and represents the Critical Care Societies Collaborative
    Am J Crit Care 22:469-73. 2013
    ..2013;41(11):2467-2475. The full report provides a comprehensive description of the Working Group's process and outcome. ..
  19. pmc Automated influenza-like illness reporting--an efficient adjunct to traditional sentinel surveillance
    W Katherine Yih
    Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA
    Public Health Rep 129:55-63. 2014
    ..We compared an electronic health record-based influenza-like illness (ILI) surveillance system with manual sentinel surveillance and virologic data to evaluate the utility of the automated system for routine ILI surveillance...
  20. doi request reprint Automated surveillance of health care-associated infections
    Michael Klompas
    Infection Control Department, Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Clin Infect Dis 48:1268-75. 2009
    ..The efficiency and objectivity of these methods make them promising candidates for more manageable and meaningful benchmarking within and between facilities...
  21. doi request reprint Inclusion of 30-day postdischarge detection triples the incidence of hospital-onset methicillin-resistant Staphylococcus aureus
    Taliser R Avery
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts 02215, USA
    Infect Control Hosp Epidemiol 33:114-21. 2012
    ..Hospitalized patients are at increased risk for acquisition of methicillin-resistant Staphylococcus aureus (MRSA). As hospital length of stay shortens, hospital-acquired MRSA events may be more likely to be detected after discharge...
  22. pmc Electronic Support for Public Health: validated case finding and reporting for notifiable diseases using electronic medical data
    Ross Lazarus
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA, USA
    J Am Med Inform Assoc 16:18-24. 2009
    ..Source code for this highly interoperable application is freely available under an approved open-source license at http://esphealth.org...
  23. pmc Real-time surveillance for tuberculosis using electronic health record data from an ambulatory practice in eastern Massachusetts
    Michael S Calderwood
    Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Public Health Rep 125:843-50. 2010
    ..We report on the development and validation of a TB detection algorithm for EHR data followed by implementation in a live surveillance and reporting system...
  24. doi request reprint Introduction to "a compendium of strategies to prevent healthcare-associated infections in acute care hospitals: 2014 updates"
    Deborah S Yokoe
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts
    Infect Control Hosp Epidemiol 35:455-9. 2014
    ....
  25. doi request reprint Comparison of electronic laboratory reports, administrative claims, and electronic health record data for acute viral hepatitis surveillance
    Joshua Allen-Dicker
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA
    J Public Health Manag Pract 18:209-14. 2012
    ..Public health surveillance systems for acute hepatitis are limited: clinician reporting is insensitive and electronic laboratory reporting is nonspecific. Insurance claims and electronic health records are potential alternative sources...
  26. doi request reprint Fonsecaea monophora cerebral phaeohyphomycosis: case report of successful surgical excision and voriconazole treatment and review
    Sophia Koo
    Division of Infectious Diseases, Brigham and Women s Hospital, 75 Francis Street, PBB A4, Boston, MA 02115, USA
    Med Mycol 48:769-74. 2010
    ..She discontinued antifungal therapy after an 18-month treatment course, and has remained free of any clinical or radiographic evidence of recurrent abscess formation three years later...
  27. doi request reprint Developing a new, national approach to surveillance for ventilator-associated events*
    Shelley S Magill
    1Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA 2Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 3Infection Control Department, Brigham and Women s Hospital, Boston, MA 4Society for Healthcare Epidemiology of America, Arlington, VA 5Division of Pulmonary and Critical Care Medicine, Rush University School of Medicine, Chicago, IL 6Critical Care Societies Collaborative American Association of Critical Care Nurses, American College of Chest Physicians, American Thoracic Society, Society of Critical Care Medicine 7School of Nursing, Critical and Acute Care, University of Virginia, Charlottesville, VA 8Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 9Division of Infectious Diseases, University of Iowa Carver College of Medicine, Iowa City, IA 10Healthcare Infection Control Practices Advisory Committee Surveillance Working Group, Atlanta, GA 11Infection Prevention and Control Department, Rochester General Health System, Rochester, NY 12Association for Professionals in Infection Control and Epidemiology, Washington, DC 13Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 14Department of Cardiology, Zablocki VA Medical Center, Milwaukee, WI 15Hospital Epidemiology and Quality Improvement, University of California
    Crit Care Med 41:2467-75. 2013
    ..To develop and implement an objective, reliable approach to surveillance for ventilator-associated events in adult patients...
  28. doi request reprint A compendium of strategies to prevent healthcare-associated infections in acute care hospitals
    Deborah S Yokoe
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Infect Control Hosp Epidemiol 29:S12-21. 2008
    ....
  29. ncbi request reprint Ventilator-associated pneumonia--the wrong quality measure for benchmarking
    Michael Klompas
    Department of Ambulatory Care and Prevention, Harvard Medical School, Harvard Pilgrim Health Care, and Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    Ann Intern Med 147:803-5. 2007
    ..Ventilator-associated pneumonia should be excluded from compulsory reporting initiatives until we develop and validate more objective outcome measures that meaningfully reflect quality of care for ventilated patients...
  30. doi request reprint Descriptive epidemiology and attributable morbidity of ventilator-associated events
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts
    Infect Control Hosp Epidemiol 35:502-10. 2014
    ..46 [95% CI, 1.37-1.55]), and higher hospital mortality risk (odds ratio, 1.98 [95% CI, 1.60-2.44]). Conclusions. VAEs are common and morbid. Prevention strategies targeting VAEs are needed. ..
  31. doi request reprint Obesity as a risk factor for severe influenza-like illness
    Noelle M Cocoros
    Bureau of Infectious Disease, Massachusetts Department of Public Health, Jamaica Plain, MA, USA
    Influenza Other Respir Viruses 8:25-32. 2014
    ..Obesity was recognized as in independent risk factor for influenza during the 2009 H1N1 influenza pandemic...