James I Kim

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi Generation of adaptive regulatory T cells by alloantigen is required for some but not all transplant tolerance protocols
    James I Kim
    Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Transplantation 91:707-13. 2011
  2. ncbi Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival
    James I Kim
    Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
    Eur J Immunol 40:1369-74. 2010
  3. ncbi Inhibition of transplantation tolerance by immune senescence is reversed by endocrine modulation
    Gaoping Zhao
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Sci Transl Med 3:87ra52. 2011
  4. ncbi Islet alone versus islet after kidney transplantation: metabolic outcomes and islet graft survival
    Shaoping Deng
    Harrison Department of Surgical Research, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    Transplantation 88:820-5. 2009
  5. ncbi Therapeutic siRNA silencing in inflammatory monocytes in mice
    Florian Leuschner
    Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Nat Biotechnol 29:1005-10. 2011
  6. ncbi Inhibition of ICAM-1/LFA-1 interactions prevents B-cell-dependent anti-CD45RB-induced transplantation tolerance
    Xiaolun Huang
    Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Transplantation 85:675-80. 2008
  7. ncbi Progress toward antibody-induced transplantation tolerance
    Daniel J Moore
    Harrison Department of Surgical Research, Department of Surgery, University of Pennsylvania, USA
    Crit Rev Immunol 27:167-218. 2007
  8. ncbi Availability of suitable islet donors in the United States
    Paige M Porrett
    Department of Surgery, The University of Pennsylvania, Philadelphia, PA, USA
    Transplantation 84:280-2. 2007
  9. ncbi Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development
    Helen E MacLean
    Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Dev Biol 262:51-63. 2003

Collaborators

  • Shaoping Deng
  • Daniel J Moore
  • Andrew J Caton
  • Yi Gu
  • Matthias Nahrendorf
  • Jing Wang
  • Helen E MacLean
  • J F Markmann
  • Henry Kronenberg
  • Gabriel Courties
  • Kang Mi Lee
  • Florian Leuschner
  • Gaoping Zhao
  • Xiaolun Huang
  • Heidi Yeh
  • Paige M Porrett
  • Patrick E Duff
  • Brett Marinelli
  • Virna Cortez-Retamozo
  • Ralph Weissleder
  • Matthew R O'connor
  • Stuart Milstein
  • Peter Libby
  • Yoshiko Iwamoto
  • Won Woo Lee
  • Ji Lei
  • Victor Koteliansky
  • Rostic Gorbatov
  • Robert Langer
  • Jessica S Donahoe
  • Kevin Love
  • Filip K Swirski
  • Andita Newton
  • Maozhu Yang
  • Tatiana I Novobrantseva
  • Hila Epstein-Barash
  • Daniel G Anderson
  • Partha Dutta
  • Peter Panizzi
  • William Cantley
  • Jamie Wong
  • Mikael J Pittet
  • Moh Moh Lian
  • Samsher Sonawane
  • Mohammad Mohiuddin
  • Moh-Moh Lian
  • Adam Frank
  • Clyde F Barker

Detail Information

Publications9

  1. ncbi Generation of adaptive regulatory T cells by alloantigen is required for some but not all transplant tolerance protocols
    James I Kim
    Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Transplantation 91:707-13. 2011
    ..We examined whether the immune response to a transplant allograft results in the peripheral generation of aTregs...
  2. ncbi Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival
    James I Kim
    Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
    Eur J Immunol 40:1369-74. 2010
    ..These results demonstrate that disruption of binding of GITR with GITR ligand may be an important strategy in prolonging allograft survival...
  3. ncbi Inhibition of transplantation tolerance by immune senescence is reversed by endocrine modulation
    Gaoping Zhao
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Sci Transl Med 3:87ra52. 2011
    ..The aging of the immune system ("immune senescence") is a significant barrier to immune tolerance, but this barrier can be overcome by targeting sex steroid production with commonly used clinical therapeutics...
  4. ncbi Islet alone versus islet after kidney transplantation: metabolic outcomes and islet graft survival
    Shaoping Deng
    Harrison Department of Surgical Research, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    Transplantation 88:820-5. 2009
    ....
  5. ncbi Therapeutic siRNA silencing in inflammatory monocytes in mice
    Florian Leuschner
    Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Nat Biotechnol 29:1005-10. 2011
    ....
  6. ncbi Inhibition of ICAM-1/LFA-1 interactions prevents B-cell-dependent anti-CD45RB-induced transplantation tolerance
    Xiaolun Huang
    Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Transplantation 85:675-80. 2008
    ..We have investigated the hypothesis that alteration in ICAM-1 expression is required for tolerance induction...
  7. ncbi Progress toward antibody-induced transplantation tolerance
    Daniel J Moore
    Harrison Department of Surgical Research, Department of Surgery, University of Pennsylvania, USA
    Crit Rev Immunol 27:167-218. 2007
    ....
  8. ncbi Availability of suitable islet donors in the United States
    Paige M Porrett
    Department of Surgery, The University of Pennsylvania, Philadelphia, PA, USA
    Transplantation 84:280-2. 2007
    ..We characterize donor utilization for islet transplantation and estimate the number of recipients who could achieve normoglycemia through islet transplantation if the current donor pool were used...
  9. ncbi Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development
    Helen E MacLean
    Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Dev Biol 262:51-63. 2003
    ..5 in the c-maf-null. MMP-13 is known to be regulated by AP-1 and may also be a target of c-Maf. Thus, cartilage is a novel system in which c-Maf acts during development, where c-Maf is required for normal chondrocyte differentiation...