Research Topics
Species | Peter J KellySummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
Functional recovery after rehabilitation for cerebellar strokeP J Kelly
Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Boston, MA 02114, USA
Stroke 32:530-4. 2001..We studied patients admitted to a rehabilitation hospital after cerebellar stroke to quantify recovery after rehabilitation therapy and to identify variables that predicted functional outcome...
Diffusion MRI in ischemic stroke compared to pathologically verified infarctionP J Kelly
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
Neurology 56:914-20. 2001..A combined retrospective and prospective analysis of consecutive patients over a 3-year period who had a clinical diagnosis of probable new ischemic stroke, underwent diffusion MRI, and were later studied at autopsy was performed...
Homocysteine, MTHFR 677C-->T polymorphism, and risk of ischemic stroke: results of a meta-analysisP J Kelly
Stroke Service, Department of Neurology, Massachusetts General Hospital and Harvard University, Boston, MA 02114, USA
Neurology 59:529-36. 2002....
Low vitamin B6 but not homocyst(e)ine is associated with increased risk of stroke and transient ischemic attack in the era of folic acid grain fortificationPeter J Kelly
Stroke Service, Department of Neurology, VBK 802, Massachusetts General Hospital, Fruit St, Boston, MA 02114, USA
Stroke 34:e51-4. 2003..We performed a case-control study to determine the risk of stroke and transient ischemic attack (TIA) associated with tHcy and low vitamin status in a postfortification US sample...
Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) studyPeter J Kelly
Neurovascular Clinical Science Unit, Mater University Hospital and University College Dublin, Ireland
Stroke 39:100-4. 2008..We aimed to determine the change in plasma F2IP levels over time and relationship with plasma MMP-9 in tPA-treated and tPA-untreated stroke patients...
Inflammation, homocysteine, and vitamin B6 status after ischemic strokeP J Kelly
Stroke Service, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Fruit St, Boston, Mass 02114, USA
Stroke 35:12-5. 2004..We investigated B6 status, tHcy, and inflammation (measured by C-reactive protein [CRP]) in patients with stroke and controls...
Population-based study of ABCD2 score, carotid stenosis, and atrial fibrillation for early stroke prediction after transient ischemic attack: the North Dublin TIA studyOrla C Sheehan
Neurovascular Clinical Science Unit, Mater University Hospital University College Dublin, Ireland
Stroke 41:844-50. 2010..We investigated the external validity of the ABCD(2) score, carotid stenosis, and atrial fibrillation for prediction of early recurrent stroke after TIA...
Diagnostic usefulness of the ABCD2 score to distinguish transient ischemic attack and minor ischemic stroke from noncerebrovascular events: the North Dublin TIA StudyOrla C Sheehan
Neurovascular Clinical Science Unit, Mater University Hospital, University College Dublin, Dublin, Ireland
Stroke 40:3449-54. 2009..We hypothesized that the ABCD(2) score may partly improve risk stratification due to improved discrimination of true TIA and minor ischemic stroke (MIS) from noncerebrovascular events...
Association between acute statin therapy, survival, and improved functional outcome after ischemic stroke: the North Dublin Population Stroke StudyDanielle Ní Chróinín
Neurovascular Clinical Science Unit, Catherine McCauley Research Centre, Mater University Hospital, Nelson Street, Dublin 7, Ireland
Stroke 42:1021-9. 2011..Statins improve infarct volume and neurological outcome in animal stroke models. We investigated the relationship between statin therapy and ischemic stroke outcome in the North Dublin Population Stroke Study...
Improved late survival and disability after stroke with therapeutic anticoagulation for atrial fibrillation: a population studyNiamh Hannon
Neurovascular Clinical Science Unit, Catherine McAuley Research Centre, Nelson Street, Mater University Hospital, Dublin 7, Ireland
Stroke 42:2503-8. 2011....
Carotid plaque inflammation on 18F-fluorodeoxyglucose positron emission tomography predicts early stroke recurrenceMichael Marnane
Neurovascular Clinical Science Unit, Mater University Hospital University College Dublin at Dublin Academic Medical Centre, Ireland
Ann Neurol 71:709-18. 2012..Using combined (18) F-fluorodeoxyglucose positron-emission tomography (FDG-PET)/computed tomography, we investigated the relation between inflammation-related FDG uptake and stroke recurrence...
Stroke associated with atrial fibrillation--incidence and early outcomes in the north Dublin population stroke studyNiamh Hannon
Neurovascular Clinical Science Unit, Mater University Hospital, Dublin, Ireland
Cerebrovasc Dis 29:43-9. 2010..Prospective population-based studies are important to accurately determine the incidence and characteristics of stroke associated with atrial fibrillation (AF), while avoiding selection bias which may complicate hospital-based studies...
Dose-related association of MTHFR 677T allele with risk of ischemic stroke: evidence from a cumulative meta-analysisSimon Cronin
Neurovascular Clinical Science Unit, Mater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland
Stroke 36:1581-7. 2005..Data are conflicting concerning ischemic stroke risk associated with a common polymorphism in the gene encoding 5,10-methylenetetrahydrofolate reductase (MTHFR 677C-->T), which predisposes to hyperhomocystinemia in vivo...
Functional recovery following rehabilitation after hemorrhagic and ischemic strokePeter J Kelly
Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Boston, MA 02114, USA
Arch Phys Med Rehabil 84:968-72. 2003..Patients with the most severely disabling ICH improved more than those with cerebral infarction of comparable severity. Initial severity of disability, age, and duration of therapy best predicted functional outcome after rehabilitation...
Addition of brain and carotid imaging to the ABCD² score to identify patients at early risk of stroke after transient ischaemic attack: a multicentre observational studyAine Merwick
Department of Neurology, Mater Misericordiae University Hospital, Dublin Academic Medical Centre, Ireland
Lancet Neurol 9:1060-9. 2010..We aimed to develop two new versions of the score: one that was based on preclinical information and one that was based on imaging and other secondary care assessments...
Homocyst(e)ine and strokeKaren L Furie
Stroke Service, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, USA
Semin Neurol 26:24-32. 2006....
Potassium channel antibody associated encephalopathy presenting with a frontotemporal dementia like syndromeAndrew McKeon
Department of Neurology, Mater Misericordiae University Hospital, Dublin, Ireland
Arch Neurol 64:1528-30. 2007..To describe a patient who presented with features suggestive of frontotemporal dementia (FTD) but with some atypical findings and antibodies to neuronal voltage-gated potassium channels (VGKC-Abs)...
Safety and efficacy of IV-TPA for ischaemic stroke in clinical practice--a Bayesian analysisKillian E T O'Rourke
Stroke Service, Department of Neurology, and Neurovascular Clinical Science Unit, Mater University Hospital and University College Dublin, 1 Nelson Street, Dublin 7, Ireland
Cerebrovasc Dis 28:572-81. 2009..We used a Bayesian approach to interpret and sequentially combine phase 4 studies of IV-TPA within 3 h for acute ischaemic stroke to quantify the cumulative evidence for the efficacy and safety of this therapy in clinical practice...
Stroke subtype classification to mechanism-specific and undetermined categories by TOAST, A-S-C-O, and causative classification system: direct comparison in the North Dublin population stroke studyMichael Marnane
Neurovascular Clinical Science Unit, Mater University Hospital University College Dublin, Ireland
Stroke 41:1579-86. 2010..We hypothesized that both CCS and ASCO would reduce the proportion of patients classified as cause undetermined compared with the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) scheme in a large population-based stroke study...
Steroid-responsive recurrent encephalopathy in a patient with cerebral amyloid angiopathyJohn C McHugh
Department of Neurology, Mater Misericordiae University Hospital, Dublin, Ireland
Cerebrovasc Dis 23:66-9. 2007
Focal status epilepticus as atypical presentation of pyridoxine-dependent epilepsyAkira Yoshii
Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Child Neurol 20:696-8. 2005..This case illustrates that pyridoxine-dependent epilepsy, although rare, must be included in the differential diagnosis of focal seizures, especially when the seizures are refractory to traditional antiepileptic drugs...
Mortality and recovery after stroke in the GambiaRichard W Walker
Department of Medicine, North Tyneside General Hospital, Tyne and Wear, UK
Stroke 34:1604-9. 2003..There are no previously published studies of the long-term outcome of stroke in sub-Saharan Africa. Our goal was to determine the case fatality, time to and cause of death, and recovery in a hospital cohort of stroke patients in The Gambia...
A taxonomy for homework used by mental health case managers when working with individuals diagnosed with severe mental illnessPeter J Kelly
Department of Psychology, Illawarra Institute for Mental Health, University of Wollongong, Wollongong, NSW, 2522, Australia
Community Ment Health J 43:565-81. 2007..Homework focused on CAN areas of need in relation to Company, Psychological Distress, Psychotic Symptoms and Daytime Activities. The applications of the taxonomy for both researchers and case managers are discussed...
