Nada Y Kalaany

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi request reprint LXRS and FXR: the yin and yang of cholesterol and fat metabolism
    Nada Y Kalaany
    Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
    Annu Rev Physiol 68:159-91. 2006
  2. ncbi request reprint Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1
    David A Guertin
    Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Department of Biology, Cambridge, Massachusetts 02141, USA
    Dev Cell 11:859-71. 2006
  3. ncbi request reprint LXRs regulate the balance between fat storage and oxidation
    Nada Y Kalaany
    Howard Hughes Medical Institute, Department of Pharmacology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
    Cell Metab 1:231-44. 2005

Collaborators

  • David J Mangelsdorf
  • JAY HORTON
  • David A Guertin
  • Carson C Thoreen
  • Deanna M Stevens
  • Michael Brown
  • Jason Moffat
  • Kevin J Fitzgerald
  • David M Sabatini
  • Aurora A Burds

Detail Information

Publications3

  1. ncbi request reprint LXRS and FXR: the yin and yang of cholesterol and fat metabolism
    Nada Y Kalaany
    Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
    Annu Rev Physiol 68:159-91. 2006
    ..Together, LXRs and FXR represent potential therapeutic targets for the treatment and prevention of numerous metabolic and lipid-related diseases...
  2. ncbi request reprint Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1
    David A Guertin
    Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Department of Biology, Cambridge, Massachusetts 02141, USA
    Dev Cell 11:859-71. 2006
    ..Thus, mTORC1 function is essential in early development, mLST8 is required only for mTORC2 signaling, and mTORC2 is a necessary component of the Akt-FOXO and PKCalpha pathways...
  3. ncbi request reprint LXRs regulate the balance between fat storage and oxidation
    Nada Y Kalaany
    Howard Hughes Medical Institute, Department of Pharmacology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
    Cell Metab 1:231-44. 2005
    ..These studies suggest that, by selectively sensing the cholesterol component of a lipid-rich diet, LXRs govern the balance between storage and oxidation of dietary fat...