F B Johnson

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi request reprint Telomeres, the nucleolus and aging
    F B Johnson
    Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA
    Curr Opin Cell Biol 10:332-8. 1998
  2. ncbi request reprint Dyskeratosis congenita, telomeres and human ageing
    R A Marciniak
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Trends Genet 16:193-5. 2000
  3. pmc The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
    F B Johnson
    Department of Biology, 68-280 Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    EMBO J 20:905-13. 2001
  4. ncbi request reprint Molecular biology of aging
    F B Johnson
    Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA
    Cell 96:291-302. 1999
  5. ncbi request reprint Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells
    F B Johnson
    Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA
    Cancer Res 60:1162-7. 2000
  6. pmc Nucleolar localization of the Werner syndrome protein in human cells
    R A Marciniak
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Proc Natl Acad Sci U S A 95:6887-92. 1998

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Telomeres, the nucleolus and aging
    F B Johnson
    Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA
    Curr Opin Cell Biol 10:332-8. 1998
    ..The accumulation of ribosomal DNA circles is a cause of aging in this organism. The possible relevance of this mechanism to human aging is also being considered...
  2. ncbi request reprint Dyskeratosis congenita, telomeres and human ageing
    R A Marciniak
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Trends Genet 16:193-5. 2000
    ....
  3. pmc The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
    F B Johnson
    Department of Biology, 68-280 Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    EMBO J 20:905-13. 2001
    ..Our findings indicate that Sgs1p and WRN function in telomere maintenance, and suggest that telomere defects contribute to the pathogenesis of WS and perhaps other RecQ helicase diseases...
  4. ncbi request reprint Molecular biology of aging
    F B Johnson
    Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA
    Cell 96:291-302. 1999
  5. ncbi request reprint Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells
    F B Johnson
    Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA
    Cancer Res 60:1162-7. 2000
    ..Thus, mechanisms by which RecQ helicases and topoisomerase III proteins cooperate to maintain genomic stability in model organisms likely apply to humans...
  6. pmc Nucleolar localization of the Werner syndrome protein in human cells
    R A Marciniak
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Proc Natl Acad Sci U S A 95:6887-92. 1998
    ..Understanding the function of WRN in these organisms of vastly differing lifespan may yield new insights into the mechanisms of lifespan determination...