Roy M John

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi Catheter-based ablation for ventricular arrhythmias
    Roy M John
    Department of Medicine, Cardiovascular Division, Cardiac Arrhythmia Service SH 5, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Curr Cardiol Rep 13:399-406. 2011
  2. doi Ventricular arrhythmias in patients with implanted cardioverter defibrillators
    Roy M John
    Department of Medicine, Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Trends Cardiovasc Med 22:169-73. 2012
  3. doi Ventricular arrhythmias and sudden cardiac death
    Roy M John
    Department of Medicine, Division of Cardiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Lancet 380:1520-9. 2012
  4. pmc The incidence, pattern, and prognostic value of left ventricular myocardial scar by late gadolinium enhancement in patients with atrial fibrillation
    Tomas G Neilan
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts
    J Am Coll Cardiol 62:2205-14. 2013
  5. doi Electrocardiographic left ventricular scar burden predicts clinical outcomes following infarct-related ventricular tachycardia ablation
    Pipin Kojodjojo
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Heart Rhythm 10:1119-24. 2013
  6. doi Reentrant ventricular tachycardia originating from the periaortic region in the absence of overt structural heart disease
    Koichi Nagashima
    Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA
    Circ Arrhythm Electrophysiol 7:99-106. 2014
  7. pmc Obesity and sleep apnea are independently associated with adverse left ventricular remodeling and clinical outcome in patients with atrial fibrillation and preserved ventricular function
    Ravi V Shah
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, MA
    Am Heart J 167:620-6. 2014
  8. pmc Direct comparison of adjacent endocardial and epicardial electrograms: implications for substrate mapping
    Michifumi Tokuda
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    J Am Heart Assoc 2:e000215. 2013
  9. pmc Acute failure of catheter ablation for ventricular tachycardia due to structural heart disease: causes and significance
    Michifumi Tokuda
    Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Am Heart Assoc 2:e000072. 2013
  10. doi Catheter ablation of ventricular tachycardia in nonischemic heart disease
    Michifumi Tokuda
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Circ Arrhythm Electrophysiol 5:992-1000. 2012

Collaborators

Detail Information

Publications34

  1. doi Catheter-based ablation for ventricular arrhythmias
    Roy M John
    Department of Medicine, Cardiovascular Division, Cardiac Arrhythmia Service SH 5, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Curr Cardiol Rep 13:399-406. 2011
    ..In particular, endocardial ablation techniques have been complemented by newer approaches such as percutaneous epicardial ablation. In rare cases, transcoronary alcohol ablation can be effective for life-threatening arrhythmia...
  2. doi Ventricular arrhythmias in patients with implanted cardioverter defibrillators
    Roy M John
    Department of Medicine, Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Trends Cardiovasc Med 22:169-73. 2012
    ..Strategies to reduce or prevent ventricular arrhythmias and shocks are a prime area of focus and development in patients with ICDs...
  3. doi Ventricular arrhythmias and sudden cardiac death
    Roy M John
    Department of Medicine, Division of Cardiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Lancet 380:1520-9. 2012
    ..Advances in understanding of genetic arrhythmia syndromes and in technology for mapping and ablation of ventricular arrhythmias, and enhanced algorithms in implantable devices for rhythm management, have contributed to improved outcomes...
  4. pmc The incidence, pattern, and prognostic value of left ventricular myocardial scar by late gadolinium enhancement in patients with atrial fibrillation
    Tomas G Neilan
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts
    J Am Coll Cardiol 62:2205-14. 2013
    ..This study sought to identify the frequency, pattern, and prognostic significance of left ventricular (LV) late gadolinium enhancement (LGE) in patients with atrial fibrillation (AF)...
  5. doi Electrocardiographic left ventricular scar burden predicts clinical outcomes following infarct-related ventricular tachycardia ablation
    Pipin Kojodjojo
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Heart Rhythm 10:1119-24. 2013
    ..Whether the amount of left ventricular scar (LVS) affects outcomes after VT ablation is not known...
  6. doi Reentrant ventricular tachycardia originating from the periaortic region in the absence of overt structural heart disease
    Koichi Nagashima
    Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA
    Circ Arrhythm Electrophysiol 7:99-106. 2014
    ..We hypothesized that multiple morphologies (MMs) of inducible left ventricular outflow tract VT may indicate a scar-related VT that can mimic idiopathic VT...
  7. pmc Obesity and sleep apnea are independently associated with adverse left ventricular remodeling and clinical outcome in patients with atrial fibrillation and preserved ventricular function
    Ravi V Shah
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, MA
    Am Heart J 167:620-6. 2014
    ..We tested the hypothesis that sleep apnea (SA) would have a body mass index (BMI) independent association with adverse left ventricular (LV) remodeling and clinical outcomes in patients with AF and preserved LV function...
  8. pmc Direct comparison of adjacent endocardial and epicardial electrograms: implications for substrate mapping
    Michifumi Tokuda
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    J Am Heart Assoc 2:e000215. 2013
    ..This study compares the characteristics of electrograms at endocardial sites adjacent to abnormal epicardial sites...
  9. pmc Acute failure of catheter ablation for ventricular tachycardia due to structural heart disease: causes and significance
    Michifumi Tokuda
    Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Am Heart Assoc 2:e000072. 2013
    ..The aim of this study is to identify causes for failure in patients with structural heart disease and to assess the relation of this acute outcome to longer-term management and outcomes...
  10. doi Catheter ablation of ventricular tachycardia in nonischemic heart disease
    Michifumi Tokuda
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Circ Arrhythm Electrophysiol 5:992-1000. 2012
    ..The aim of this study was to describe the outcomes after catheter ablation for nonischemic VT in a large cohort and to compare the electrophysiological findings and outcomes according to the type of underlying disease...
  11. doi Correlates and prognosis of early recurrence after catheter ablation for ventricular tachycardia due to structural heart disease
    Koichi Nagashima
    From the Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA
    Circ Arrhythm Electrophysiol 7:883-8. 2014
    ..This study assesses the timing, correlates, and prognostic significance of early VT recurrence after ablation...
  12. doi Outcomes of cardiac perforation complicating catheter ablation of ventricular arrhythmias
    Michifumi Tokuda
    Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Circ Arrhythm Electrophysiol 4:660-6. 2011
    ..The study aims to investigate the incidence, management, and hospital outcomes of cardiac perforation complicating catheter ablation for ventricular arrhythmias...
  13. doi Transcoronary ethanol ablation for recurrent ventricular tachycardia after failed catheter ablation: an update
    Michifumi Tokuda
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Circ Arrhythm Electrophysiol 4:889-96. 2011
    ..After encouraging results with transcoronary ethanol ablation (TCEA), we began offering TCEA routinely when endocardial and epicardial RFCA failed or a deep intramural substrate was likely...
  14. doi Feasibility, efficacy, and safety of radiofrequency ablation of atrial fibrillation guided by monitoring of the initial impedance decrease as a surrogate of catheter contact
    Tobias Reichlin
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts, USA Division of Cardiology, University Hospital, Basel, Switzerland
    J Cardiovasc Electrophysiol 26:390-6. 2015
    ..We aimed to assess feasibility, efficacy, and safety of an ablation approach guided by initial impedance decrease...
  15. pmc Myocardial extracellular volume expansion and the risk of recurrent atrial fibrillation after pulmonary vein isolation
    Tomas G Neilan
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts Division of Cardiology, Department of Medicine, Cardiac MR PET CT Program, Division of Radiology, Massachusetts General Hospital, Boston, Massachusetts
    JACC Cardiovasc Imaging 7:1-11. 2014
    ....
  16. doi Substrate characterization and catheter ablation for monomorphic ventricular tachycardia in patients with apical hypertrophic cardiomyopathy
    Keiichi Inada
    Cardiac Arrhythmia Division, Cardiovascular Division, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA02115, USA
    J Cardiovasc Electrophysiol 22:41-8. 2011
    ..VT Ablation in Apical Hypertrophic Cardiomyopathy. ..
  17. doi Incidence and predictors of major complications from contemporary catheter ablation to treat cardiac arrhythmias
    Marius Bohnen
    Cardiac Arrhythmia Service, Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Heart Rhythm 8:1661-6. 2011
    ..Updated understanding of the risks of catheter ablation is important because techniques have evolved for procedures treating non-life-threatening as well as potentially lethal arrhythmias...
  18. doi Ventricular arrhythmias near the distal great cardiac vein: challenging arrhythmia for ablation
    Koichi Nagashima
    From the Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA
    Circ Arrhythm Electrophysiol 7:906-12. 2014
    ..Catheter ablation for ventricular arrhythmia (VA) near the distal great cardiac vein (GCV) is often challenging, and data are limited...
  19. doi Anterograde conduction to the His bundle during right ventricular overdrive pacing distinguishes septal pathway atrioventricular reentry from atypical atrioventricular nodal reentrant tachycardia
    Koichi Nagashima
    Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts
    Heart Rhythm 12:735-43. 2015
    ..Specifically, excluding the presence and participation of an AP may require multiple diagnostic maneuvers...
  20. doi Ventricular tachycardia in cardiac sarcoidosis: characterization of ventricular substrate and outcomes of catheter ablation
    Saurabh Kumar
    From the Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA
    Circ Arrhythm Electrophysiol 8:87-93. 2015
    ..We sought to examine the ventricular substrate and outcomes of catheter ablation in this population...
  21. doi Reducing radiation exposure in the electrophysiology laboratory: it is more than just fluoroscopy times!
    Eyal Nof
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts Leviev Heart Center, Sheba Medical Center, Tel Hashomer, Israel
    Pacing Clin Electrophysiol 38:136-45. 2015
    ..To exposure in patients undergoing cardiac electrophysiology (EP) ablation. This included the use of a "very low" dose protocol, and the impact of angulations and patient body mass index (BMI) on radiation dose as a mean to reduce exposure...
  22. doi Resetting criteria during ventricular overdrive pacing successfully differentiate orthodromic reentrant tachycardia from atrioventricular nodal reentrant tachycardia despite interobserver disagreement concerning QRS fusion
    Jonathan Z Rosman
    Department of Cardiovascular Medicine at Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Heart Rhythm 8:2-7. 2011
    ..The end of the TZ is marked by the first beat with a stable QRS morphology but is a subjective assessment. Disagreement concerning this beat may change tachycardia diagnosis...
  23. doi Avoiding tachycardia alteration or termination during attempted entrainment mapping of atrial tachycardia related to atrial fibrillation ablation
    Chirag R Barbhaiya
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts
    Heart Rhythm 12:32-5. 2015
    ..Entrainment can be useful for mapping atrial tachycardias (ATs) after atrial fibrillation (AF) ablation but may result in AT alteration or termination...
  24. doi Relation of the unipolar low-voltage penumbra surrounding the endocardial low-voltage scar to ventricular tachycardia circuit sites and ablation outcomes in ischemic cardiomyopathy
    Nagesh Chopra
    Arrhythmia Service, Division of Cardiovascular Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Cardiovasc Electrophysiol 25:602-8. 2014
    ..We hypothesized that the size of the unipolar LVA "penumbra" beyond the overlying bipolar scar may predict outcome of endocardial VT ablation...
  25. doi Multicenter experience with transvenous lead extraction in arrhythmogenic right ventricular cardiomyopathy (ARVC)
    Melanie Maytin
    Brigham and Women s Hospital, Boston, Massachusetts
    Pacing Clin Electrophysiol 36:1280-3. 2013
    ..Given predominant right ventricular disease with thinning of the wall, there is concern regarding the safety of transvenous lead extraction (TLE) in ARVC...
  26. pmc Effect of sleep apnea and continuous positive airway pressure on cardiac structure and recurrence of atrial fibrillation
    Tomas G Neilan
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA
    J Am Heart Assoc 2:e000421. 2013
    ....
  27. doi Effect of therapeutic INR on activated clotting times, heparin dosage, and bleeding risk during ablation of atrial fibrillation
    Sandeep Gautam
    Division of Cardiovascular Medicine, Brigham and Women s Hospital, 45 Francis St, Boston, MA 02115, USA
    J Cardiovasc Electrophysiol 22:248-54. 2011
    ..Heparin is administered during the procedure, but the effect of elevated INR on heparin requirements and target activation clotting times (ACT) ≥ 350 seconds during ablation is unknown...
  28. doi Multicenter experience with extraction of the Riata/Riata ST ICD lead
    Melanie Maytin
    Brigham and Women s Hospital, Boston, Massachusetts Electronic address
    Heart Rhythm 11:1613-8. 2014
    ..In November 2011, the Food and Drug Administration issued a class I recall of Riata and Riata ST implantable cardioverter-defibrillator leads. Management recommendations regarding the recall have remained controversial...
  29. doi Lead implant duration does not always predict ease of extraction: extraction sheath may be required at < 1 year
    Melanie Maytin
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Pacing Clin Electrophysiol 34:1615-20. 2011
    ..Most operators agree that leads with short implant durations can be extracted easily but data regarding defibrillator (implantable cardioverter-defibrillator [ICD]) leads and newer generation leads with backfilled coils are limited...
  30. doi Percutaneous access of the epicardial space for mapping ventricular and supraventricular arrhythmias in patients with and without prior cardiac surgery
    Kurt C Roberts-Thomson
    Department of Cardiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Cardiovasc Electrophysiol 21:406-11. 2010
    ..There is a paucity of data on the success rates of achieving percutaneous epicardial access in different groups of patients...
  31. doi Initial impedance decrease as an indicator of good catheter contact: insights from radiofrequency ablation with force sensing catheters
    Tobias Reichlin
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts University Hospital, Basel, Switzerland Electronic address
    Heart Rhythm 11:194-201. 2014
    ..Tissue heating during RF application results in an impedance decrease at the catheter tip...
  32. doi Multicenter experience with extraction of the Sprint Fidelis implantable cardioverter-defibrillator lead
    Melanie Maytin
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 56:646-50. 2010
    ..This study was undertaken to determine the safety and feasibility of extraction of the Sprint Fidelis (Medtronic, Minneapolis, Minnesota) lead...
  33. doi Disseminated malignancies masquerading as cardiovascular implantable electronic devices infections
    Pipin Kojodjojo
    Arrhythmia Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA, USA
    Europace 13:821-4. 2011
    ..We present our experience of CIED pocket disruptions thought to be due to infection and referred to our institution for lead extraction but instead proved to be the first manifestations of disseminated malignancies...
  34. doi Catheter ablation for premature ventricular contractions and ventricular tachycardia in patients with heart failure
    Saurabh Kumar
    Cardiac Arrhythmia Service, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA
    Curr Cardiol Rep 16:522. 2014
    ....