Hadine Joffe

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Program, Department of Psychiatry, Massachusetts General Hospital, Boston, Mass 02114, USA
    J Clin Psychiatry 68:943-50. 2007
  2. pmc Adverse effects of induced hot flashes on objectively recorded and subjectively reported sleep: results of a gonadotropin-releasing hormone agonist experimental protocol
    Hadine Joffe
    Center for Women s Mental Health, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Menopause 20:905-14. 2013
  3. pmc The impact of depot GnRH agonist on AMH levels in healthy reproductive-aged women
    H Irene Su
    MD, MSc, Department of Psychiatry, Massachusetts General Hospital, Simches Research Building, 185 Cambridge Street, Suite 2000, Boston, Massachusetts 02114
    J Clin Endocrinol Metab 98:E1961-6. 2013
  4. pmc Relapse of vasomotor symptoms after discontinuation of the selective serotonin reuptake inhibitor escitalopram: results from the menopause strategies: finding lasting answers for symptoms and health research network
    Hadine Joffe
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Menopause 20:261-8. 2013
  5. pmc Metabolic activity in the insular cortex and hypothalamus predicts hot flashes: an FDG-PET study
    Hadine Joffe
    Center for Women s Mental Health, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston Massachusetts 02114, USA
    J Clin Endocrinol Metab 97:3207-15. 2012
  6. pmc Lifetime history of depression and anxiety disorders as a predictor of quality of life in midlife women in the absence of current illness episodes
    Hadine Joffe
    Department of Psychiatry, Center for Women s Mental Health, Massachusetts General Hospital, Harvard Medical School, Simches Research Bldg, 185 Cambridge St, Ste 2000, Boston, MA 02114, USA
    Arch Gen Psychiatry 69:484-92. 2012
  7. doi request reprint Eszopiclone improves insomnia and depressive and anxious symptoms in perimenopausal and postmenopausal women with hot flashes: a randomized, double-blinded, placebo-controlled crossover trial
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Clinical Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Obstet Gynecol 202:171.e1-171.e11. 2010
  8. doi request reprint Augmentation of venlafaxine and selective serotonin reuptake inhibitors with zolpidem improves sleep and quality of life in breast cancer patients with hot flashes: a randomized, double-blind, placebo-controlled trial
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Menopause 17:908-16. 2010
  9. pmc Evaluation and management of sleep disturbance during the menopause transition
    Hadine Joffe
    Center for Women s Mental Health, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Semin Reprod Med 28:404-21. 2010
  10. ncbi request reprint Treatment of premenstrual worsening of depression with adjunctive oral contraceptive pills: a preliminary report
    Hadine Joffe
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 68:1954-62. 2007

Detail Information

Publications47

  1. ncbi request reprint Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Program, Department of Psychiatry, Massachusetts General Hospital, Boston, Mass 02114, USA
    J Clin Psychiatry 68:943-50. 2007
    ..Treatment strategies that target all of these symptoms together have not been investigated to date...
  2. pmc Adverse effects of induced hot flashes on objectively recorded and subjectively reported sleep: results of a gonadotropin-releasing hormone agonist experimental protocol
    Hadine Joffe
    Center for Women s Mental Health, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Menopause 20:905-14. 2013
    ..Using objective and subjective measurements, we examined the impact of hot flashes on sleep by inducing hot flashes with a gonadotropin-releasing hormone agonist...
  3. pmc The impact of depot GnRH agonist on AMH levels in healthy reproductive-aged women
    H Irene Su
    MD, MSc, Department of Psychiatry, Massachusetts General Hospital, Simches Research Building, 185 Cambridge Street, Suite 2000, Boston, Massachusetts 02114
    J Clin Endocrinol Metab 98:E1961-6. 2013
    ..Anti-Müllerian hormone (AMH) produced by ovarian granulosa cells may serve as a marker of ovarian reserve, but it is not clear whether this marker is useful during GnRHa treatment...
  4. pmc Relapse of vasomotor symptoms after discontinuation of the selective serotonin reuptake inhibitor escitalopram: results from the menopause strategies: finding lasting answers for symptoms and health research network
    Hadine Joffe
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Menopause 20:261-8. 2013
    ..We hypothesized that relapse of VMS to baseline levels after SSRI cessation would be common and predicted by menopausal and psychological characteristics...
  5. pmc Metabolic activity in the insular cortex and hypothalamus predicts hot flashes: an FDG-PET study
    Hadine Joffe
    Center for Women s Mental Health, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston Massachusetts 02114, USA
    J Clin Endocrinol Metab 97:3207-15. 2012
    ..Previous studies have implicated the insula during the perception of hot flashes and the hypothalamus in thermoregulatory dysfunction...
  6. pmc Lifetime history of depression and anxiety disorders as a predictor of quality of life in midlife women in the absence of current illness episodes
    Hadine Joffe
    Department of Psychiatry, Center for Women s Mental Health, Massachusetts General Hospital, Harvard Medical School, Simches Research Bldg, 185 Cambridge St, Ste 2000, Boston, MA 02114, USA
    Arch Gen Psychiatry 69:484-92. 2012
    ....
  7. doi request reprint Eszopiclone improves insomnia and depressive and anxious symptoms in perimenopausal and postmenopausal women with hot flashes: a randomized, double-blinded, placebo-controlled crossover trial
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Clinical Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Obstet Gynecol 202:171.e1-171.e11. 2010
    ..Menopause-associated insomnia is commonly associated with other symptoms (hot flashes, depression, anxiety). Given frequent symptom cooccurrence, therapies targeting sleep may provide an important approach to treatment during midlife...
  8. doi request reprint Augmentation of venlafaxine and selective serotonin reuptake inhibitors with zolpidem improves sleep and quality of life in breast cancer patients with hot flashes: a randomized, double-blind, placebo-controlled trial
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Menopause 17:908-16. 2010
    ..Alternative strategies are needed. We hypothesized that augmentation of SSRI/SNRI therapy with hypnotic agents would optimize hot flash therapy by improving sleep and quality of life...
  9. pmc Evaluation and management of sleep disturbance during the menopause transition
    Hadine Joffe
    Center for Women s Mental Health, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Semin Reprod Med 28:404-21. 2010
    ..Sleep disorders in midlife women should be treated because substantial improvements in quality of life and health outcomes are achievable...
  10. ncbi request reprint Treatment of premenstrual worsening of depression with adjunctive oral contraceptive pills: a preliminary report
    Hadine Joffe
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 68:1954-62. 2007
    ..Oral contraceptive pills (OCPs) stabilize reproductive hormones and treat premenstrual dysphoric disorder. Management of depression that breaks through premenstrually has not been studied...
  11. pmc Increased estradiol and improved sleep, but not hot flashes, predict enhanced mood during the menopausal transition
    Hadine Joffe
    Center for Women s Mental Health, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 96:E1044-54. 2011
    ..Estrogen therapy (ET) and the hypnotic agent zolpidem were selected as interventions in a three-arm, double-blind, placebo-controlled trial to distinguish the effects of estradiol, sleep, and hot flashes on depression...
  12. ncbi request reprint Menstrual dysfunction prior to onset of psychiatric illness is reported more commonly by women with bipolar disorder than by women with unipolar depression and healthy controls
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Clinical Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 67:297-304. 2006
    ..However, it is not always clear whether such abnormalities, reflecting disruption of the hypothalamic-pituitary-gonadal (HPG) axis, are caused by psychotropic treatments or associated with the disorder per se...
  13. ncbi request reprint Reproductive biology and psychotropic treatments in premenopausal women with bipolar disorder
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Clinical Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 68:10-5. 2007
    ....
  14. pmc Menstrual cycle dysfunction associated with neurologic and psychiatric disorders: their treatment in adolescents
    Hadine Joffe
    Perinatal and Reproductive Psychiatry, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Ann N Y Acad Sci 1135:219-29. 2008
    ..Use of these agents should be considered and weighed against the risk of using alternative agents, which have their own side effects, or not treating these serious neurologic and psychiatric disorders...
  15. ncbi request reprint Longitudinal follow-up of reproductive and metabolic features of valproate-associated polycystic ovarian syndrome features: A preliminary report
    Hadine Joffe
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Biol Psychiatry 60:1378-81. 2006
    ..5% of 86 women. We now determine whether polycystic ovarian syndrome (PCOS) features reverse on valproate discontinutation...
  16. pmc Depression is associated with worse objectively and subjectively measured sleep, but not more frequent awakenings, in women with vasomotor symptoms
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Menopause 16:671-9. 2009
    ..We aimed to determine if objectively measured sleep and perceived sleep quality are worse in depressed women with VMS than in nondepressed women with VMS...
  17. ncbi request reprint A putative relationship between valproic acid and polycystic ovarian syndrome: implications for treatment of women with seizure and bipolar disorders
    Hadine Joffe
    Department of Psychiatry, Massachusetts General Hospital, 15 Parkman Street, WACC 815, Boston, MA 02114, USA
    Harv Rev Psychiatry 11:99-108. 2003
  18. ncbi request reprint Impact of oral contraceptive pill use on premenstrual mood: predictors of improvement and deterioration
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Clinical Research Program, Massachusetts General Hospital, 15 Parkman Street, WACC, Boston, MA 02114, USA
    Am J Obstet Gynecol 189:1523-30. 2003
    ..The purpose of this study was to estimate risk factors for the deterioration and improvement of premenstrual mood disturbance with oral contraceptive pill use...
  19. ncbi request reprint Valproate is associated with new-onset oligoamenorrhea with hyperandrogenism in women with bipolar disorder
    Hadine Joffe
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Biol Psychiatry 59:1078-86. 2006
    ..The development of PCOS features after initiation of valproate was therefore examined in women with bipolar disorder using a standardized definition of PCOS...
  20. ncbi request reprint Estrogen therapy selectively enhances prefrontal cognitive processes: a randomized, double-blind, placebo-controlled study with functional magnetic resonance imaging in perimenopausal and recently postmenopausal women
    Hadine Joffe
    Women s Center for Behavioral Endocrinology, McLean Hospital, Harvard Medical School, Boston, MA, USA
    Menopause 13:411-22. 2006
    ....
  21. ncbi request reprint Vasomotor symptoms are associated with depression in perimenopausal women seeking primary care
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Program, Reproductive Endocrine Unit, and Medical Service, Massachusetts General Hospital, Boston, MA, USA
    Menopause 9:392-8. 2002
    ..To compare the relationship between vasomotor symptoms (hot flushes and night sweats) and depression in perimenopausal women with that in postmenopausal and older premenopausal women...
  22. ncbi request reprint Assessment and treatment of hot flushes and menopausal mood disturbance
    Hadine Joffe
    Department of Psychiatry, Perinatal and Reproductive Psychiatry Clinical Research Program, Massachusetts General Hospital, Harvard Medical School, 15 Parkman Street, WACC, Boston, MA 02114, USA
    Psychiatr Clin North Am 26:563-80. 2003
    ..As further evidence of the benefits of psychoactive medications for menopausal symptoms is established, the choice between using hormonal and nonhormonal therapies for management of menopausal symptoms will continue to evolve...
  23. pmc Vasomotor symptoms and insulin resistance in the study of women's health across the nation
    Rebecca C Thurston
    Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 97:3487-94. 2012
    ..OBJECTIVE AND MAIN OUTCOME MEASURES: We examined the associations between hot flashes/night sweats and glucose and insulin resistance over 8 yr, controlling for cardiovascular risk factors and reproductive hormones...
  24. doi request reprint Duloxetine for major depressive disorder and daytime and nighttime hot flashes associated with the menopausal transition
    Marlene P Freeman
    Massachusetts General Hospital, Harvard Medical School, USA
    Maturitas 75:170-4. 2013
    ..The secondary outcomes were vasomotor symptoms (VMS, or hot flashes), specifically assessed as daytime or nighttime, and anxiety...
  25. pmc Vasomotor symptoms and lipid profiles in women transitioning through menopause
    Rebecca C Thurston
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Obstet Gynecol 119:753-61. 2012
    ..To examine associations between vasomotor symptoms and lipids over 8 years, controlling for other cardiovascular risk factors, estradiol, and follicle-stimulating hormone...
  26. doi request reprint Paroxetine versus placebo for women in midlife after hormone therapy discontinuation
    Claudio N Soares
    Perinatal and Reproductive Psychiatry Program, Massachusetts General Hospital, Boston, USA
    Am J Med 121:159-162.e1. 2008
    ..This study examines the efficacy of paroxetine controlled-release versus placebo for the treatment of women with vasomotor symptoms after discontinuing hormone therapy...
  27. ncbi request reprint Eszopiclone in patients with insomnia during perimenopause and early postmenopause: a randomized controlled trial
    Claudio N Soares
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada, and Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
    Obstet Gynecol 108:1402-10. 2006
    ..To evaluate eszopiclone 3 mg for treatment of insomnia in perimenopausal and early postmenopausal women, as well as the impact of insomnia treatment on mood, menopause-related symptoms, and quality of life...
  28. pmc Psychosocial features associated with lifetime comorbidity of major depression and anxiety disorders among a community sample of mid-life women: the SWAN mental health study
    Jill M Cyranowski
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Depress Anxiety 29:1050-7. 2012
    ..This report evaluates clinical, psychological, social, and stress-related characteristics associated with a lifetime history of MDD and anxiety...
  29. pmc Gains in body fat and vasomotor symptom reporting over the menopausal transition: the study of women's health across the nation
    Rebecca C Thurston
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Epidemiol 170:766-74. 2009
    ..The relations between body fat changes and night sweats were not statistically significant. Body fat gains are associated with greater hot flash reporting during the menopausal transition...
  30. ncbi request reprint Physical activity and risk of vasomotor symptoms in women with and without a history of depression: results from the Harvard Study of Moods and Cycles
    Rebecca C Thurston
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Menopause 13:553-60. 2006
    ..To examine whether physical activity was associated with decreased risk of vasomotor symptoms in a prospective study of women transitioning through menopause...
  31. doi request reprint Longitudinal follow-up of bipolar disorder in women with premenstrual exacerbation: findings from STEP-BD
    Rodrigo S Dias
    Bipolar Clinic and Research Program, Massachusetts General Hospital, Boston, USA
    Am J Psychiatry 168:386-94. 2011
    ..The authors determined the course of illness and time to relapse of bipolar disorder in prospectively followed women with premenstrual exacerbation...
  32. ncbi request reprint Gender differences in bipolar disorder: retrospective data from the first 500 STEP-BD participants
    Claudia F Baldassano
    Bipolar Disorders Program, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
    Bipolar Disord 7:465-70. 2005
    ..To examine gender differences in a large sample of patients with bipolar illness...
  33. ncbi request reprint Diagnosis and management of mood disorders during the menopausal transition
    Lee S Cohen
    Department of Perinatal and Reproductive Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Med 118:93-7. 2005
    ..The benefits and risks of using hormonal and nonhormonal strategies for the management of depression and other menopause-related somatic symptoms are critically reviewed...
  34. pmc Vasomotor symptoms and menopause: findings from the Study of Women's Health across the Nation
    Rebecca C Thurston
    Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Obstet Gynecol Clin North Am 38:489-501. 2011
    ..We have reviewed the literature on VMS, emphasizing findings that have emerged from SWAN and new areas of inquiry in the area of VMS...
  35. pmc Omega-3 fatty acids for major depressive disorder associated with the menopausal transition: a preliminary open trial
    Marlene P Freeman
    Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Menopause 18:279-84. 2011
    ..We sought to obtain preliminary data regarding the efficacy of omega-3 fatty acids for major depressive disorder associated with the menopausal transition. Secondary outcomes were assessed for vasomotor symptoms (or hot flashes)...
  36. ncbi request reprint Incidence of hospitalization for postpartum psychotic and bipolar episodes in women with and without prior prepregnancy or prenatal psychiatric hospitalizations
    Bernard L Harlow
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Arch Gen Psychiatry 64:42-8. 2007
    ..Postpartum psychosis occurs in 1 to 2 cases per 1000 live births. Most studies have not distinguished postpartum psychosis from bipolar disorder or the proportion of the incidence attributable to prepregnancy psychiatric morbidity...
  37. pmc Effect of medroxyprogesterone on depressive symptoms in depressed and nondepressed perimenopausal and postmenopausal women after discontinuation of transdermal estradiol therapy
    Maria Pia Rogines-Velo
    Center for Women s Mental Health, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Menopause 19:471-5. 2012
    ....
  38. pmc A reproductive subtype of depression: conceptualizing models and moving toward etiology
    Jennifer L Payne
    Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Harv Rev Psychiatry 17:72-86. 2009
    ..This review will provide evidence supporting reproductive depression as a distinct clinical entity with specific treatment approaches and a unique biology that is separate from nonreproductive depression...
  39. ncbi request reprint Menopause and mood
    Claudio N Soares
    Center for Women s Mental Health, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Clin Obstet Gynecol 47:576-91. 2004
  40. doi request reprint Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial
    Lee S Cohen
    From the 1Massachusetts General Hospital, Boston, MA 2MsFLASH Data Coordinating Center, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 3VA Medical Center, University of Minnesota, Minneapolis, MN 4School of Nursing, Indiana University, Indianapolis, IN 5Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN 6Group Health Research Institute, Group Health Cooperative, Seattle, WA 7Departments of Obstetrics Gynecology and Epidemiology, University of Washington School of Medicine, Seattle, WA 8Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 9Division of Research, Kaiser Permanente Medical Program of Northern California, Oakland, CA 10Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA and 11School of Nursing, University of Washington, Seattle, WA
    Menopause 21:347-54. 2014
    ..This study aims to determine the efficacy and tolerability of omega-3 fatty acids in reducing vasomotor symptoms (VMS) frequency and bother in perimenopausal and postmenopausal women...
  41. pmc A gonadotropin-releasing hormone agonist model demonstrates that nocturnal hot flashes interrupt objective sleep
    Hadine Joffe
    Women s Hormones and Aging Research Program, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA Department of Psychosocial Oncology and Palliative Care Medicine, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA Center for Women s Mental Health, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA
    Sleep 36:1977-85. 2013
    ..Sleep interruption is often reported by women with hot flashes and night sweats (or vasomotor symptoms, VMS). Although women report that VMS awaken them, polysomnography (PSG) studies have not consistently supported this contention...
  42. pmc Mood symptoms after natural menopause and hysterectomy with and without bilateral oophorectomy among women in midlife
    Carolyn J Gibson
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Obstet Gynecol 119:935-41. 2012
    ..To examine whether mood symptoms increased more for women in the years after hysterectomy with or without bilateral oophorectomy relative to natural menopause...
  43. pmc Sociodemographic predictors of antenatal and postpartum depressive symptoms among women in a medical group practice
    Janet W Rich-Edwards
    Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Epidemiol Community Health 60:221-7. 2006
    ..This study investigated whether race/ethnicity, age, finances, and partnership status were associated with antenatal and postpartum depressive symptoms...
  44. ncbi request reprint Use of antidepressants during perimenopause
    Deborah R Kim
    Psychosomatic Medicine, Department of Psychiatry, Hospital of the University of Pennsylvania, 3535 Market Street, 2nd Floor Philadelphia, PA 19104, USA
    Womens Health (Lond Engl) 2:627-37. 2006
    ....
  45. ncbi request reprint Relation of daily urinary hormone patterns to vasomotor symptoms in a racially/ethnically diverse sample of midlife women: study of women's health across the nation
    Ellen B Gold
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, University of California, Davis, CA 95616, USA
    Reprod Sci 14:786-97. 2007
    ....
  46. ncbi request reprint Escitalopram versus ethinyl estradiol and norethindrone acetate for symptomatic peri- and postmenopausal women: impact on depression, vasomotor symptoms, sleep, and quality of life
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    Menopause 13:780-6. 2006
    ..To examine the efficacy and tolerability of escitalopram (ESCIT) compared to estrogen and progestogen therapy (EPT) for the treatment of symptomatic peri- and postmenopausal women...
  47. ncbi request reprint Efficacy of 17beta-estradiol on depression: is estrogen deficiency really necessary?
    Claudio N Soares
    J Clin Psychiatry 63:451; author reply 451-2. 2002

Research Grants3

  1. PHYSIOLOGY OF ESTROGEN'S MOOD EFFECT IN MENOPAUSAL WOMEN
    Hadine Joffe; Fiscal Year: 2007
    ..Such training will lay the foundation for a career of clinical investigation into the physiology of perimenopausal depression and the impact of hot flushes on sleep, mood, and quality-of-life. ..
  2. Defining the Mechanisms of Menopause-Associated Sleep and Mood Disturbances
    Hadine Joffe; Fiscal Year: 2010
    ..This work has important public health relevance because it will inform the development of rational therapeutic strategies and lead to novel treatment paradigms for menopause- associated depression. ..