Research Topics | Eric M IsselbacherSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Thoracic and abdominal aortic aneurysmsEric M Isselbacher
Thoracic Aortic Center and Cardiology Division, Massachusetts General Hospital, 55 Fruit St, YAW-5A-5800, Boston, MA 02114, USA
Circulation 111:816-28. 2005
Iatrogenic aortic dissectionJames L Januzzi
Massachusetts General Hospital, Boston, Massachusetts, USA
Am J Cardiol 89:623-6. 2002
Branch vessel complications are increased in aortic dissection patients with renal insufficiencyJoshua A Beckman
Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA
Vasc Med 9:267-70. 2004..Upon recognition, renal impairment indicates a need for close monitoring, aggressive blood pressure control, and evaluation of aortic branch vessel circulations...
Acute abdominal aortic dissection: insight from the International Registry of Acute Aortic Dissection (IRAD)Santi Trimarchi
IRCCS Policlinico San Donato, Cardiovascular Center E Malan, University of Milan, San Donato Milanese, Italy
J Vasc Surg 46:913-919. 2007..The aim of this study was to identify clinical characteristics, therapeutic approaches, risk factors for mortality, in-hospital outcome, and long-term results of this cohort, thus clarifying its natural history...
Implications of periaortic hematoma in patients with acute aortic dissection (from the International Registry of Acute Aortic Dissection)Debabrata Mukherjee
Gill Heart Institute, University of Kentucky, Lexington, Kentucky, USA
Am J Cardiol 96:1734-8. 2005..The early identification and aggressive management of patients with periaortic hematomas may potentially improve clinical outcomes...
Role and results of surgery in acute type B aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD)Santi Trimarchi
Cardiovascular Center E Malan, Policlinico San Donato, Via Morandi 30, 20097 San Donato Milanese, Italy
Circulation 114:I357-64. 2006....
Acute limb ischemia associated with type B aortic dissection: clinical relevance and therapyPeter K Henke
Section of Vascular Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Mich, USA
Surgery 140:532-9; discussion 539-40. 2006..The goal of the current study is to characterize the presentation, therapy, and outcomes of acute limb ischemia (ALI) associated with type B aortic dissection (AoD)...
Simple risk models to predict surgical mortality in acute type A aortic dissection: the International Registry of Acute Aortic Dissection scoreVincenzo Rampoldi
Cardiovascular Center E Malan, Policlinico S Donato, S Donato Milanese, Italy
Ann Thorac Surg 83:55-61. 2007..We report a predictive score to identify risk of death that may be helpful to assist surgeons who are considering whether to proceed with surgical correction in the case of patients in extreme clinical risk...
Partial thrombosis of the false lumen in patients with acute type B aortic dissectionThomas T Tsai
Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, MI 48109 5853, USA
N Engl J Med 357:349-59. 2007..Patency or thrombosis of the false lumen in type B acute aortic dissection has been found to predict outcomes. The prognostic implications of partial thrombosis of the false lumen have not yet been elucidated...
Aortic diameter >or = 5.5 cm is not a good predictor of type A aortic dissection: observations from the International Registry of Acute Aortic Dissection (IRAD)Linda A Pape
University of Massachusetts Medical School, 55 Lake Ave N, Worcester, MA 01655, USA
Circulation 116:1120-7. 2007..However, few studies of acute aortic dissection patients and aortic size exist. We used data from our registry of acute aortic dissection patients to better understand the relationship between aortic diameter and type A dissection...
Acute type B aortic dissection: does aortic arch involvement affect management and outcomes? Insights from the International Registry of Acute Aortic Dissection (IRAD)Thomas T Tsai
University of Michigan Cardiovascular Center, 1500 E Medical Center Dr, Ann Arbor, MI 48109 5853, USA
Circulation 116:I150-6. 2007..However, the treatment of TB-AAD with aortic arch involvement (AAI) remains an unresolved issue...
Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experienceSanti Trimarchi
Istituto Policlinico S Donato, Milanese, Italy
J Thorac Cardiovasc Surg 129:112-22. 2005....
Characterizing the young patient with aortic dissection: results from the International Registry of Aortic Dissection (IRAD)James L Januzzi
Thoracic Aorta Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USA
J Am Coll Cardiol 43:665-9. 2004..Surprisingly, the mortality risk for young AoD patients is not lower than older AoD patients...
Acute type A aortic dissection in the elderly: clinical characteristics, management, and outcomes in the current eraRajendra H Mehta
University of Michigan, Ann Arbor, Michigan 48105, USA
J Am Coll Cardiol 40:685-92. 2002..We sought to evaluate the clinical characteristics, management, and outcomes of elderly patients with acute type A aortic dissection...
Acute type B aortic dissection in elderly patients: clinical features, outcomes, and simple risk stratification ruleRajendra H Mehta
Department of Cardiology, University of Michigan, Ann Arbor, Michigan 48105, USA
Ann Thorac Surg 77:1622-8; discussion 1629. 2004..Accordingly, we sought to evaluate the clinical features and outcomes and derive a simple risk stratification rule for elderly with ABAD...
Gender-related differences in acute aortic dissectionChristoph A Nienaber
Division of Cardiology, University Hospital Rostock, Rostock School of Medicine, Ernst Heydemann Strasse 6, 18057 Rostock, Germany
Circulation 109:3014-21. 2004..Few data exist on gender-related differences in clinical presentation, diagnostic findings, management, and outcomes in acute aortic dissection (AAD)...
Comparison of aortic dissection in patients with and without Marfan's syndrome (results from the International Registry of Aortic Dissection)James L Januzzi
Thoracic Aorta Center and Cardiology Division, Massachusetts General Hospital, Boston, 02114, USA
Am J Cardiol 94:400-2. 2004..Our data support the importance of aneurysm surveillance and prophylactic surgical intervention for patients with Marfan's syndrome to potentially reduce the risk of mortality...
Differences in clinical presentation, management, and outcomes of acute type a aortic dissection in patients with and without previous cardiac surgeryJ Stewart Collins
University of Michigan, Ann Arbor, Mich, USA
Circulation 110:II237-42. 2004....
Chronobiological patterns of acute aortic dissectionRajendra H Mehta
Division of Cardiology, University of Michigan, Ann Arbor, USA
Circulation 106:1110-5. 2002..However, the effects of the time of the day, the day of the week, or monthly/seasonal changes on acute aortic dissection (AAD) have not been well studied...
Choice of computed tomography, transesophageal echocardiography, magnetic resonance imaging, and aortography in acute aortic dissection: International Registry of Acute Aortic Dissection (IRAD)Andrew G Moore
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Cardiol 89:1235-8. 2002
Clinical profiles and outcomes of acute type B aortic dissection in the current era: lessons from the International Registry of Aortic Dissection (IRAD)Toru Suzuki
Division of Cardiology, University Hospital Rostock, Rostock School of Medicine, E.-Heydemann-Str. 6, 18057 Rostock, Germany
Circulation 108:II312-7. 2003..Factors associated with increased in-hospital mortality ("the deadly triad") should be identified and taken into consideration for risk stratification and decision-making...
Dissection of the descending thoracic aorta: looking into the futureEric M Isselbacher
J Am Coll Cardiol 50:805-7. 2007
64-slice multidetector computed tomography (MDCT) for detection of aortic regurgitation and quantification of severityDavinder S Jassal
Department of Medicine, Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, and the Department of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
Invest Radiol 42:507-12. 2007..Recent advances in 64-slice multidetector computed tomography (MDCT) provide an opportunity to assess coronary artery disease, left ventricular function and, potentially, valvular heart disease...
The crossed swords sign: insights into the dilemma of repair in bileaflet mitral valve prolapseRonen Beeri
Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
J Am Soc Echocardiogr 20:698-702. 2007..Some patients show two crossed jets oppositely directed from the coaptation zone. We hypothesized that these indicate bileaflet lesions requiring complex repair...
Intramural hematoma of the aorta: should we let down our guard?Eric M Isselbacher
Am J Med 113:244-6. 2002
Syncope in acute aortic dissection: diagnostic, prognostic, and clinical implicationsBrahmajee K Nallamothu
University of Michigan Medical School, Ann Arbor, Michigan, USA
Am J Med 113:468-71. 2002..If these complications are excluded, syncope alone does not appear to increase the risk of death independently...
Association of painless acute aortic dissection with increased mortalitySeung Woo Park
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:1252-7. 2004..9%; P = .04). CONCLUSION: Patients with painless AAD had syncope, congestive heart failure, or stroke. Compared with patients who have painful AAD, patients who have painless AAD have higher mortality, especially when AAD is type B...
The winter peak in the occurrence of acute aortic dissection is independent of climateRajendra H Mehta
Duke Clinical Research Institute, Durham, NC, USA
Chronobiol Int 22:723-9. 2005....
Acute aortic dissection presenting with congestive heart failure: results from the International Registry of Acute Aortic DissectionJames L Januzzi
J Am Coll Cardiol 46:733-5. 2005
Does circadian and seasonal variation in occurrence of acute aortic dissection influence in-hospital outcomes?Rajendra H Mehta
Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
Chronobiol Int 22:343-51. 2005..While highest incidence of AAD occurred in the morning and winter, clinical events (including mortality) were similar during the four different periods of the 24 h (chi2 = 1.9, p = 0.60) and seasonal (chi2 = 1.2, p = 0.75) periods...
Comparing on-pump and off-pump coronary artery bypass grafting: numerous studies but few conclusions: a scientific statement from the American Heart Association council on cardiovascular surgery and anesthesia in collaboration with the interdisciplinary wFrank W Sellke
Beth Israel Deaconess Medical Center, USA
Circulation 111:2858-64. 2005..To definitively answer the remaining questions of whether either strategy is superior and in which patients, a large-scale prospective randomized trial is required...
Preoperative cardiac evaluation for vascular surgeryHovig V Chitilian
Department of Anesthesia and Critical Care, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02214, USA
Int Anesthesiol Clin 43:1-14. 2005
Clinical characteristics of hypotension in patients with acute aortic dissectionThomas T Tsai
University of Michigan, Ann Arbor, USA
Am J Cardiol 95:48-52. 2005..We concluded that hypotension that occurred in >25% of patients who had AAD was associated with a much higher rate of in-hospital adverse events. Our study also identified factors associated with hypotension in patients who had AAD...
Acute intramural hematoma of the aorta: a mystery in evolutionArturo Evangelista
Hospital General Universitari Vall d'Hebron, Barcelona, Spain
Circulation 111:1063-70. 2005..Fully 16% of patients have evidence of evolution to dissection on serial imaging...
