Research Topics
| Chin HurSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
Coxibs versus combination NSAID and PPI therapy for chronic pain: an exploration of the risks, benefits, and costsChin Hur
Institute for Technology Assessment, Massachusetts General Hospital Gastrointestinal Unit, Harvard Medical School, Boston, 02114, USA
Ann Pharmacother 40:1052-63. 2006....
The management of small polyps found by virtual colonoscopy: results of a decision analysisChin Hur
Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
Clin Gastroenterol Hepatol 5:237-44. 2007..Decision-analytic techniques were used to compare the outcomes of 2 management strategies for smaller (6-9 mm) polyps discovered by CTC...
The effect of prior colonic imaging on endoscopic productivity: potential impact of computed tomographic colonographyChin Hur
Gastrointestinal Unit, Massachusetts General Hospital, 101 Merrimac Street, 10th Floor, Boston, MA 02114, USA
Clin Gastroenterol Hepatol 3:1124-7. 2005..This case-control study was undertaken to test the hypothesis that colonoscopy examinations resulting from FP CTC studies would take longer to complete than negative screening colonoscopies...
Development, calibration, and validation of a U.S. white male population-based simulation model of esophageal adenocarcinomaChin Hur
Massachusetts General Hospital Institute for Technology Assessment, Boston, Massachusetts, United States of America
PLoS ONE 5:e9483. 2010..S. and western world. The aim of the study was to begin the investigation of this rapid rise by developing, calibrating, and validating a mathematical disease simulation model of EAC using available epidemiologic data...
Patient preferences for the management of high-grade dysplasia in Barrett's esophagusChin Hur
Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
Dig Dis Sci 50:116-25. 2005..In summary, when patients with Barrett's esophagus were presented with three options to manage HGD, the majority chose endoscopic surveillance. Familiarity with endoscopic surveillance was the predominant reason for the choice...
Analysis of aspirin-associated risks in healthy individualsChin Hur
Harvard Medical School, Institute for Technology Assessment and Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114 4719, USA
Ann Pharmacother 39:51-7. 2005..Aspirin therapy is widely accepted for patients with documented cardiovascular disease, but there is a growing trend among healthy individuals to use aspirin as primary prevention for both cardiovascular disease and cancer...
An analysis of the potential impact of computed tomographic colonography (virtual colonoscopy) on colonoscopy demandChin Hur
Gastrointestinal Unit, Harvard Medicasl School, Boston, MA, USA
Gastroenterology 127:1312-21. 2004..However, no formal analysis of the impact of CTC on colonoscopy demand has been reported...
The cost-effectiveness of aspirin versus cyclooxygenase-2-selective inhibitors for colorectal carcinoma chemoprevention in healthy individualsChin Hur
Institute for Technology Assessment, Massachusetts General Hospital, 101 Merrimac Street, 10th Floor, Boston, MA 02114, USA
Cancer 101:189-97. 2004..Accruing evidence suggests that cyclooxygenase-2-selective inhibitors (coxibs) may be effective for colorectal carcinoma (CRC) chemoprevention but would not provide the primary cardiac benefit of aspirin...
Patient preferences for the chemoprevention of colorectal cancerChin Hur
Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA, USA
Dig Dis Sci 54:2207-14. 2009..These data serve to inform physicians and researchers regarding the variability and factors that affect patient preferences for CRC chemoprevention...
Quality of life in patients with various Barrett's esophagus associated health statesChin Hur
Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, USA
Health Qual Life Outcomes 4:45. 2006..The purpose of this study was to determine the health related quality of life associated with Barrett's esophagus and many of the pivotal health states associated with Barrett's HGD management...
Patient preferences for the chemoprevention of esophageal adenocarcinoma in Barrett's esophagusChin Hur
Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
Am J Gastroenterol 103:2432-42. 2008..Our aim was to determine and characterize preferences for these two drugs in patients with BE...
The cost effectiveness of radiofrequency ablation for Barrett's esophagusChin Hur
Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Gastroenterology 143:567-75. 2012..We analyzed the effectiveness and cost effectiveness of RFA for the management of BE...
Cost-effectiveness of aspirin chemoprevention for Barrett's esophagusChin Hur
Gastrointestinal Unit and The Institute for Technology Assessment, Massachusetts General Hospital, Boston, USA
J Natl Cancer Inst 96:316-25. 2004..We used a modeling approach to determine and compare the effectiveness and cost-effectiveness of aspirin with and without endoscopic surveillance to prevent esophageal adenocarcinoma...
The impact of obesity on the rise in esophageal adenocarcinoma incidence: estimates from a disease simulation modelChung Yin Kong
Institute for Technology Assessment, Harvard Medical School, Boston, MA 02114, USA
Cancer Epidemiol Biomarkers Prev 20:2450-6. 2011..A concurrent increase in obesity has led some to suggest a relationship between the two trends. We explore the extent of this relationship...
Cost-effectiveness of endoscopic surveillance of gastric ulcers to improve survivalJennifer M Yeh
Center for Health Decision Science, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Gastrointest Endosc 72:33-43. 2010..Endoscopic surveillance of presumed-benign gastric ulcers may detect missed malignancy, but its impact on long-term outcomes is uncertain...
Cost-effectiveness of photodynamic therapy for treatment of Barrett's esophagus with high grade dysplasiaChin Hur
Gastrointestinal Unit and Institute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Dig Dis Sci 48:1273-83. 2003..In conclusion, PDT increases life expectancy and is cost-effective when compared to endoscopic surveillance and surgical esophagectomy...
Screening and surveillance for Barrett's esophagus: current issues and future directionsSung E Choi
Institute for Technology Assessment, Boston, Massachusetts, USA
Curr Opin Gastroenterol 28:377-81. 2012..Our article discusses the current understanding of screening and surveillance options for Barrett's esophagus and emerging concepts that have the potential to improve the effectiveness and cost-effectiveness of surveillance...
Cost-effectiveness of treatment and endoscopic surveillance of precancerous lesions to prevent gastric cancerJennifer M Yeh
Center for Health Decision Science, Harvard School of Public Health, Boston, MA 02115, USA
Cancer 116:2941-53. 2010..The objective of this study was to estimate the clinical benefits and cost-effectiveness of treatment and endoscopic surveillance to prevent gastric cancer...
Cost-effectiveness of prophylactic surgery for duodenal cancer in familial adenomatous polyposisWesley H Greenblatt
Institute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts, USA
Cancer Epidemiol Biomarkers Prev 18:2677-84. 2009..Because no clinical trials have assessed this recommendation, a modeling approach was used to evaluate the cost-effectiveness of various treatment strategies...
Aspirin protects against Barrett's esophagus in a multivariate logistic regression analysisZehra B Omer
Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, USA
Clin Gastroenterol Hepatol 10:722-7. 2012..We analyzed characteristics of patients with BE for factors that might be used in screening and management...
Analysis of barriers to and patients' preferences for CT colonography for colorectal cancer screening in a nonadherent urban populationWendy Ho
Massachusetts General Hospital, Boston, USA
AJR Am J Roentgenol 195:393-7. 2010..The aim of this study was to evaluate patients' barriers against colorectal cancer screening tests and to assess patients' preferences and cost influences for CT colonography (CTC) in a nonadherent urban subpopulation...
Treatment of Barrett's esophagus with high-grade dysplasia or cancer: predictors of surgical versus endoscopic therapyPatrick Yachimski
Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Clin Gastroenterol Hepatol 6:1206-11. 2008..Both esophagectomy and endoscopic ablation are treatment options. The aim of this study was to identify predictors of surgical versus endoscopic therapy at a tertiary center...
Secular trends in patients diagnosed with Barrett's esophagusPatrick Yachimski
Blake 4, Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA
Dig Dis Sci 55:960-6. 2010....
Development of an empirically calibrated model of gastric cancer in two high-risk countriesJennifer M Yeh
Program in Health Decision Science, Department of Health Policy and Management, Harvard School of Public Health, 718 Huntington Avenue, 2nd Floor, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 17:1179-87. 2008..As better data become available, the model can be refined and recalibrated, and, as such, be used as an iterative tool to assess the likely health and economic outcomes associated with gastric cancer prevention strategies...
Staging MR lymphangiography of the axilla for early breast cancer: cost-effectiveness analysisPari V Pandharipande
Department of Radiology, Institute for Technology Assessment, Massachusetts General Hospital, 101 Merrimac St, 10th Fl, Boston, MA 02114, USA
AJR Am J Roentgenol 191:1308-19. 2008..The purpose of this study was to compare the cost-effectiveness of MR lymphangiography-based strategies with that of sentinel lymph node (SLN) biopsy alone in the axillary staging of early breast cancer...
Certolizumab pegol compared to natalizumab in patients with moderate to severe Crohn's disease: results of a decision analysisAshwin N Ananthakrishnan
Gastrointestinal Unit, Massachusetts General Hospital Crohn s and Colitis Center, 165 Cambridge Street, 9th Floor, Boston, MA 02114, USA
Dig Dis Sci 57:472-80. 2012..In patients failing two anti-TNF agents, a choice exists between using a third-anti-TNF therapy or natalizumab (NAT), an α-4 integrin inhibitor. A cost-effectiveness analysis comparing these competing strategies has not been performed...
Consensus guidelines in the management of branch duct intraductal papillary mucinous neoplasm: a cost-effectiveness analysisEdward S Huang
Gastrointestinal Unit, Massachusetts General Hospital, 10th Floor, Boston, MA 02114, USA
Dig Dis Sci 55:852-60. 2010..The aim of this study was to determine the cost effectiveness of consensus guideline implementation in the management of BD-IPMN...
Rescreening of persons with a negative colonoscopy result: results from a microsimulation modelAmy B Knudsen
Institute for Technology Assessment, Massachusetts General Hospital, 101 Merrimac Street, 10th Floor, Boston, MA 02114, USA
Ann Intern Med 157:611-20. 2012..Persons with a negative result on screening colonoscopy are recommended to repeat the procedure in 10 years...
Radiofrequency ablation versus nephron-sparing surgery for small unilateral renal cell carcinoma: cost-effectiveness analysisPari V Pandharipande
Department of Radiology, Institute for Technology Assessment, Massachusetts General Hospital, 101 Merrimac St, Boston, MA 02114, USA
Radiology 248:169-78. 2008....
Correlation of polyp number and family history of colon cancer with germline MYH mutationsWon-Seok Jo
Gastrointestinal Unit and Department of Medicine, Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Clin Gastroenterol Hepatol 3:1022-8. 2005..A significant number reported a strong family history of cancer that was consistent with HNPCC. MYH testing thus can be considered for patients who meet clinical criteria for HNPCC in the absence of DNA mismatch repair gene mutations...
Upper endoscopy in patients with acute myocardial infarction and upper gastrointestinal bleeding: results of a decision analysisPatrick Yachimski
Blake 4 Gastrointestinal Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Dig Dis Sci 54:701-11. 2009..The utility of upper endoscopy (esophagogastroduodenoscopy, EGD) and endoscopic therapy must be weighed against safety considerations...
Can Mucosal Healing Be a Cost-effective Endpoint for Biologic Therapy in Crohn's Disease? A Decision AnalysisAshwin N Ananthakrishnan
Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts Harvard Medical School, Boston, Massachusetts Institute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts
Inflamm Bowel Dis 19:37-44. 2013..Whether treatment to achieve MH is a cost-effective endpoint has not been established previously...
Strategies for the prevention of postoperative recurrence in Crohn's disease: results of a decision analysisAshwin N Ananthakrishnan
Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Am J Gastroenterol 106:2009-17. 2011..Several options exist for the prevention of postoperative recurrence in CD, but the comparative cost effectiveness of these competing strategies has not been previously analyzed...
Risks and benefits of infliximab for the treatment of Crohn's diseaseCorey A Siegel
Section of Gastroenterology and Hepatology, Inflammatory Bowel Disease Center, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Lebanon, New Hampshire, USA
Clin Gastroenterol Hepatol 4:1017-24; quiz 976. 2006..These data should help guide decision making and the informed consent process when considering the use of infliximab for the treatment of Crohn's disease...
Esophageal capsule endoscopy for Barrett's esophagus screening: a hard pill to swallow?Chin Hur
Clin Gastroenterol Hepatol 5:307-9. 2007
