Jianmin Huang

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi Novel P2 promoter-derived HNF4alpha isoforms with different N-terminus generated by alternate exon insertion
    Jianmin Huang
    MassGeneral Hospital for Children, Harvard Medical School, Boston, Massachusetts 02114 2696, USA
    Exp Cell Res 315:1200-11. 2009
  2. ncbi Boosting native promoter activities with non-adjacent response-element multimers
    Jianmin Huang
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, MA 02114 2696, USA
    J Biotechnol 150:259-67. 2010
  3. ncbi Expression of HNF4alpha variants in pancreatic islets and Ins-1 beta cells
    Jianmin Huang
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, MA 02114 2696, USA
    Diabetes Metab Res Rev 24:533-43. 2008

Detail Information

Publications3

  1. ncbi Novel P2 promoter-derived HNF4alpha isoforms with different N-terminus generated by alternate exon insertion
    Jianmin Huang
    MassGeneral Hospital for Children, Harvard Medical School, Boston, Massachusetts 02114 2696, USA
    Exp Cell Res 315:1200-11. 2009
    ..We recommend inclusion of exon 1E and nearby DNA sequences in screening for HNF4alpha mutations and polymorphisms in genetic analyses of MODY1 and T2DM...
  2. ncbi Boosting native promoter activities with non-adjacent response-element multimers
    Jianmin Huang
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, MA 02114 2696, USA
    J Biotechnol 150:259-67. 2010
    ..Augmentation of three promoters suggests that this approach is potentially applicable to other promoters for gene therapy and might obviate the need for viral promoters...
  3. ncbi Expression of HNF4alpha variants in pancreatic islets and Ins-1 beta cells
    Jianmin Huang
    Pediatric Endocrine Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, MA 02114 2696, USA
    Diabetes Metab Res Rev 24:533-43. 2008
    ..Because some variants lack the N-terminal activation function 1 (AF-1) and/or C-terminal inhibitory F domain, defining their tissue-specific regulation and function is important for understanding pancreatic beta cell behaviour...