Research Topics
| Jim C HuSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
Androgen-deprivation therapy for nonmetastatic prostate cancer is associated with an increased risk of peripheral arterial disease and venous thromboembolismJim C Hu
Institute of Urologic Oncology, Department of Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA
Eur Urol 61:1119-28. 2012..However, few studies have examined its effect on the peripheral vascular system...- Determinants of treatment regret in low-income, uninsured men with prostate cancerJim C Hu
Division of Urology, Brigham and Women s Hospital, Lank Center for Genitourinary Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Urology 72:1274-9. 2008..The regret of a prostate cancer treatment choice, a significant dimension of health-related quality of life, has not been well-characterized. Little is known about its association with the fear of cancer recurrence or spirituality... - Determinants of performing radical prostatectomy pelvic lymph node dissection and the number of lymph nodes removed in elderly menJim C Hu
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
Urology 77:402-6. 2011..We characterized determinants of performance and extent of PLND during radical prostatectomy in elderly men... - Utilization and outcomes of minimally invasive radical prostatectomyJim C Hu
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
J Clin Oncol 26:2278-84. 2008..We assessed utilization, complications, lengths of stay, and salvage therapy rates for MIRP versus open radical prostatectomy assessed whether MIRP surgeon volume is associated with better outcomes... - Initial experience with robot-assisted minimally-invasive nephroureterectomyJim C Hu
Division of Urology, Brigham and Women s Hospital, Lank Center for Genitourinary Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
J Endourol 22:699-704. 2008..Various techniques have been described for laparoscopic nephroureterectomy. We reviewed our initial experience of laparoscopic nephroureterectomy with robot-assisted extravesical excision of the distal ureter and bladder cuff... - Comparative effectiveness of minimally invasive vs open radical prostatectomyJim C Hu
Division of Urologic Surgery, Brigham and Women s Hospital, 45 Francis St, Boston, MA 02115, USA
JAMA 302:1557-64. 2009..Minimally invasive radical prostatectomy (MIRP) has diffused rapidly despite limited data on outcomes and greater costs compared with open retropubic radical prostatectomy (RRP)... 
The association of abuse and symptoms suggestive of chronic prostatitis/chronic pelvic pain syndrome: results from the Boston Area Community Health surveyJim C Hu
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, MA, USA
J Gen Intern Med 22:1532-7. 2007..To determine the effect of reported sexual, physical, or emotional abuse on the symptoms suggestive of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and to determine the effect of race/ethnicity on these patterns...- Patterns of care for radical prostatectomy in the United States from 2003 to 2005Jim C Hu
Division of Urologic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Urol 180:1969-74. 2008..The demand for minimally invasive radical prostatectomy is increasing, although population based outcomes remain unclear. We assessed use and outcomes in American men undergoing radical prostatectomy... 
The effect of postprostatectomy external beam radiotherapy on quality of life: results from the Cancer of the Prostate Strategic Urologic Research EndeavorJim C Hu
Division of Urology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Cancer 107:281-8. 2006..Postprostatectomy salvage radiotherapy may improve prostate-specific antigen (PSA) progression-free survival, but little is known about its effect on quality of life...- Perioperative complications of laparoscopic and robotic assisted laparoscopic radical prostatectomyJim C Hu
Division of Urology, Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Urol 175:541-6; discussion 546. 2006..While it remains controversial whether LRP or da Vinci RAP offers any advantages over radical retropubic prostatectomy, LRP and RAP are being used more frequently. We reviewed our experience with these minimally invasive techniques... - Reduced penile size and treatment regret in men with recurrent prostate cancer after surgery, radiotherapy plus androgen deprivation, or radiotherapy aloneArti Parekh
Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Urology 81:130-4. 2013..To report the relative incidence of the perceived reduction in penile size across prostate cancer treatment modalities and to describe its effect on quality of life and treatment regret... - Cardiovascular comorbidity and treatment regret in men with recurrent prostate cancerPaul L Nguyen
Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
BJU Int 110:201-5. 2012.... - Influence of androgen deprivation therapy on all-cause mortality in men with high-risk prostate cancer and a history of congestive heart failure or myocardial infarctionPaul L Nguyen
Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Int J Radiat Oncol Biol Phys 82:1411-6. 2012.... - Population-based determinants of radical prostatectomy surgical margin positivityStephen B Williams
Division of Urologic Surgery, Center for Surgery and Public Health, Dana Farber Cancer Institute, Department of Radiation Oncology, Brigham and Women s Hospital, Boston, MA 02115, USA
BJU Int 107:1734-40. 2011..Prognosis (cohort)... - Cost implications of the rapid adoption of newer technologies for treating prostate cancerPaul L Nguyen
Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
J Clin Oncol 29:1517-24. 2011..We assessed temporal trends in their utilization and their impact on national health care spending... - Stepwise approach for nerve sparing without countertraction during robot-assisted radical prostatectomy: technique and outcomesKeith J Kowalczyk
Division of Urologic Surgery, Brigham and Women s Faulkner Hospital, Harvard Medical School, Boston, MA 02130, USA
Eur Urol 60:536-47. 2011..However, the impact of active assistant/surgeon neurovascular bundle (NVB) countertraction on sexual function outcomes has not been studied or quantified... - Comparative analysis of outcomes and costs following open radical cystectomy versus robot-assisted laparoscopic radical cystectomy: results from the US Nationwide Inpatient SampleHua yin Yu
Division of Urology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Eur Urol 61:1239-44. 2012..Although robot-assisted laparoscopic radical cystectomy (RARC) was first reported in 2003 and has gained popularity, comparisons with open radical cystectomy (ORC) are limited to reports from high-volume referral centers... - The impact of prostate size, median lobe, and prior benign prostatic hyperplasia intervention on robot-assisted laparoscopic prostatectomy: technique and outcomesAndy C Huang
Division of Urologic Surgery, Brigham and Women s Faulkner Hospital, Harvard Medical School, Boston, MA, USA
Eur Urol 59:595-603. 2011..Large prostate size, median lobes, and prior benign prostatic hyperplasia (BPH) surgery may pose technical challenges during robot-assisted laparoscopic prostatectomy (RALP)... - Athermal division and selective suture ligation of the dorsal vein complex during robot-assisted laparoscopic radical prostatectomy: description of technique and outcomesYin Lei
Division of Urologic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Eur Urol 59:235-43. 2011..Apical dissection and control of the dorsal vein complex (DVC) affects blood loss, apical positive margins, and urinary control during robot-assisted laparoscopic radical prostatectomy (RALP)... - Anatomic bladder neck preservation during robotic-assisted laparoscopic radical prostatectomy: description of technique and outcomesMarcos P Freire
Division of Urologic Surgery, Center for Surgery and Public Health, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Eur Urol 56:972-80. 2009..Robotic-assisted laparoscopic radical prostatectomy (RALP) has been rapidly adopted despite a daunting learning curve with bladder neck dissection as a challenging step for newcomers... - Technical refinement and learning curve for attenuating neurapraxia during robotic-assisted radical prostatectomy to improve sexual functionMehrdad Alemozaffar
Division of Urologic Surgery, Brigham and Women s, Harvard Medical School, Boston, MA, USA
Eur Urol 61:1222-8. 2012..Additionally, while learning curve studies often define volume thresholds for improvement, few of these studies demonstrate specific technical modifications that allow reproducibility of improved outcomes... - Trends in the care of radical prostatectomy in the United States from 2003 to 2006Stephen B Williams
Division of Urologic Surgery Center for Surgery and Public Health, Brigham and Women s Hospital, Boston, MA, USA
BJU Int 108:49-55. 2011..o determine differences in surgical outcomes by surgical approach during a period of rapid adoption of minimally invasive surgical approaches in radical prostatectomy... - Nerve-sparing technique and urinary control after robot-assisted laparoscopic prostatectomyWesley W Choi
Division of Urologic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
World J Urol 29:21-7. 2011..To characterize determinants of 4-, 12-, and 24-month urinary control after robot-assisted laparoscopic prostatectomy (RALP)... - The effect of minimally invasive and open radical prostatectomy surgeon volumeWesley W Choi
Division of Urologic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Urol Oncol 30:569-76. 2012..To determine the effect of minimally invasive radical prostatectomy (MIRP) surgeon volume on outcomes, and correlate with those of open radical prostatectomy retropubic (ORP)... - Comparative effectiveness of cryotherapy vs brachytherapy for localised prostate cancerStephen B Williams
Division of Urologic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
BJU Int 110:E92-8. 2012..Conversely, cryotherapy was associated with fewer bowel complications. Patients and providers alike should consider these population-based outcomes when discussing therapeutic options for localised prostate cancer... - Partial clamping of the renal artery during robot-assisted laparoscopic partial nephrectomy: technique and initial outcomesKeith J Kowalczyk
Department of Urology, Georgetown University Hospital, Washington, DC, USA
J Endourol 26:469-73. 2012..We describe the feasibility of partial arterial clamping (PAC) during robot-assisted partial nephrectomy (RAPN)... - Temporal national trends of minimally invasive and retropubic radical prostatectomy outcomes from 2003 to 2007: results from the 100% Medicare sampleKeith J Kowalczyk
Department of Urology, Georgetown University Hospital, Washington, DC, USA
Eur Urol 61:803-9. 2012..Although the use of minimally invasive radical prostatectomy (MIRP) has increased, there are few comprehensive population-based studies assessing temporal trends and outcomes relative to retropubic radical prostatectomy (RRP)... - Overuse of imaging for staging low risk prostate cancerWesley W Choi
Division of Urologic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02130, USA
J Urol 185:1645-9. 2011..Routine imaging for staging low risk prostate cancer is not recommended according to current guidelines. We characterized patterns of care and factors associated with imaging overuse... - Factors associated with the adoption of minimally invasive radical prostatectomy in the United StatesWilliam D Ulmer
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, Massachusetts, USA
J Urol 188:775-80. 2012..We examined the influence of patient, surgeon and hospital characteristics on the use of minimally invasive radical prostatectomy vs radical retropubic prostatectomy... - Temporal trends in radical prostatectomy complications from 1991 to 1998Jim C Hu
Department of Urology, David Geffen School of Medicine, University of California-Los Angeles, USA
J Urol 169:1443-8. 2003..However, there is capacity for improvement, as evidenced by the unchanging rate of anastomotic stricture and impotence... - Variations in surgeon volume and use of pelvic lymph node dissection with open and minimally invasive radical prostatectomySandip M Prasad
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02478, USA
Urology 72:647-52; discussion 652-3. 2008..We examined the factors associated with PLND use among men undergoing open RP (ORP) and minimally invasive RP (MIRP)... - Utilization of pharmacotherapy for erectile dysfunction following treatment for prostate cancerMichaella M Prasad
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
J Sex Med 7:1062-73. 2010..Aim. To ascertain post-treatment utilization of pharmacotherapies for erectile dysfunction (ED) using a population-based approach... - Stepwise description and outcomes of bladder neck sparing during robot-assisted laparoscopic radical prostatectomyDavid F Friedlander
Harvard School of Public Health, Brigham and Women s Hospital, Boston, Massachusetts
J Urol 188:1754-60. 2012..We compared the continence and cancer control outcomes of bladder neck sparing vs nonsparing techniques during robot-assisted laparoscopic radical prostatectomy... - Regret in men treated for localized prostate cancerJim C Hu
Department of Urology, David Geffen School of Medicine and School of Public Health, University of California, Los Angeles, Los Angeles, California, USA
J Urol 169:2279-83. 2003..Further study is needed to identify factors that predict posttreatment regret. Such information will allow patients and physicians to individualize treatment decisions, optimize quality of life and avoid medical regret... - Risk of all-cause and prostate cancer-specific mortality after brachytherapy in men with small prostate sizePaul L Nguyen
Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, MA 02115, USA
Int J Radiat Oncol Biol Phys 79:1318-22. 2011..Brachytherapy for prostate cancer can be technically challenging in men with small prostates (≤20 cc), but it is unknown whether their outcomes are different than those of men with larger prostates... - Outcomes assessment in men undergoing open retropubic radical prostatectomy, laparoscopic radical prostatectomy, and robotic-assisted radical prostatectomyKeith J Kowalczyk
Division of Urologic Surgery, Brigham and Women s Hospital, Harvard Medical School, 45 Francis St, ASB II, Boston, MA 02115, USA
World J Urol 30:85-9. 2012..To review the various methods of outcomes assessment used for effectiveness studies comparing retropubic radical prostatectomy (RRP), laparoscopic radical prostatectomy (LRP), and robotic-assisted laparoscopic prostatectomy (RALP)... - Randomized controlled trial of barbed polyglyconate versus polyglactin suture for robot-assisted laparoscopic prostatectomy anastomosis: technique and outcomesStephen B Williams
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, MA, USA
Eur Urol 58:875-81. 2010..Barbed polyglyconate sutures maintain running suture line tension and may be advantageous in RALP anastomosis for reducing this complication... - Which patients with undetectable PSA levels 5 years after radical prostatectomy are still at risk of recurrence?--implications for a risk-adapted follow-up strategyDeborah A Ahove
Smith College, Northhampton, Massachusetts, USA
Urology 76:1201-5. 2010..To determine the predictors of late prostate-specific antigen (PSA) failure among men with an undetectable PSA level 5 years after radical prostatectomy (RP)... - Radical retropubic prostatectomy and robotic-assisted laparoscopic prostatectomy: likelihood of positive surgical margin(s)Stephen B Williams
Division of Urology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Urology 76:1097-101. 2010.... - Association of androgen deprivation therapy with cardiovascular death in patients with prostate cancer: a meta-analysis of randomized trialsPaul L Nguyen
Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
JAMA 306:2359-66. 2011.... - Utilization and expense of adjuvant cancer therapies following radical prostatectomyStephen B Williams
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, Massachusetts, USA
Cancer 117:4846-54. 2011..We sought to identify the costs of adjuvant therapies following radical prostatectomy (RP) and factors associated with their receipt... - Surgical apgar outcome score: perioperative risk assessment for radical cystectomySandip M Prasad
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, Massachusetts, USA
J Urol 181:1046-52; discussion 1052-3. 2009..Using a simple 10-point scale similar to neonatal Apgar assessment we evaluated whether a surgical outcome score calculated immediately after radical cystectomy would predict major complications and mortality... - Thermal ablation vs surgery for localized kidney cancer: a Surveillance, Epidemiology, and End Results (SEER) database analysisToni K Choueiri
Dana Farber Cancer Institute, Boston, MA 02115, USA
Urology 78:93-8. 2011.... - Predicting quality of life after radical prostatectomy: results from CaPSUREJim C Hu
Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, 90095, USA
J Urol 171:703-7; discussion 707-8. 2004..Preoperative tumor characteristics do not appear to be associated with regaining baseline HRQOL, suggesting that factors not measured in this model may be important in optimizing quality of life after radical prostatectomy... - The current status of robotic oncologic surgeryHua yin Yu
Department of Urology, Kaiser Permanente Oakland Medical Center, Oakland, California, USA
CA Cancer J Clin 63:45-56. 2013..Robotic technology is widely used in oncologic surgery with demonstrated short-term advantages. However, whether the benefits of robotics justify the higher costs warrant large comparative effectiveness studies with long-term outcomes... - Time to prostate-specific antigen nadir independently predicts overall survival in patients who have metastatic hormone-sensitive prostate cancer treated with androgen-deprivation therapyToni K Choueiri
Dana Farber Cancer Institute Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Cancer 115:981-7. 2009.... - Quality of life, pain and return to normal activities following laparoscopic donor nephrectomy versus open mini-incision donor nephrectomyKent T Perry
Department of Urology, University of California-Los Angeles, Los Angeles, California, USA
J Urol 169:2018-21. 2003..In addition, the laparoscopic group showed significantly higher quality of life scores than the mini-incision group in 3 domains... - Landmarks for consistent nerve sparing during robotic-assisted laparoscopic radical prostatectomyAlexander Berry
Division of Urology, Brigham and Women's Hospital, Boston, MA 02115, USA
J Endourol 22:1565-7. 2008 - Role of surgeon volume in radical prostatectomy outcomesJim C Hu
Departments of Urology and Health Services, University of California, Los Angeles David Geffen School of Medicine and School of Public Health, Los Angeles, CA 90095-1738, USA
J Clin Oncol 21:401-5. 2003..Hospital volume is not significantly associated with outcomes after adjusting for physician volume. Further study is necessary to elucidate the mechanism of the volume-outcome effect... - Posttreatment prostate specific antigen nadir predicts prostate cancer specific and all cause mortalityYolanda D Tseng
Harvard Radiation Oncology Program, Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
J Urol 187:2068-73. 2012..We investigated whether the prostate specific antigen nadir predicts prostate cancer specific and all cause mortality in men treated in a randomized trial of radiation with or without 6 months of androgen deprivation therapy... - Hospital volume, utilization, costs and outcomes of robot-assisted laparoscopic radical prostatectomyHua yin Yu
Division of Urology, Lank Center for Genitourinary Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA
J Urol 187:1632-7. 2012.... - Health services research in urologyHua yin Yu
Division of Urology, Department of Surgery, Brigham and Women s Faulkner Hospitals, Harvard Medical School, 1153 Centre Street, Suite 4420, Boston, MA 02130, USA
World J Urol 29:273-6. 2011..We examine how HSR affects contemporary evidence-based urologic practice and its role in shaping future urologic research and care... - Comparison of outpatient narcotic prescribing patterns after minimally invasive versus retropubic and perineal radical prostatectomyKeith J Kowalczyk
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02130, USA
J Urol 186:1843-8. 2011..We characterized population based outpatient narcotic prescribing patterns after minimally invasive, retropubic and perineal radical prostatectomy... - Comparative effectiveness of perineal versus retropubic and minimally invasive radical prostatectomySandip M Prasad
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, Massachusetts, USA
J Urol 185:111-5. 2011..In our population based study we compared the use and outcomes of perineal radical prostatectomy vs retropubic and minimally invasive radical prostatectomy... - Anatomic and technical considerations for optimizing recovery of sexual function during robotic-assisted radical prostatectomyStacey Carter
Department of Urology, David Geffen School of Medicine at University of California, Los Angeles, California, USA
Curr Opin Urol 23:88-94. 2013.... - Impact of radical prostatectomy positive surgical margins on fear of cancer recurrence: results from CaPSUREY Mark Hong
Division of Urology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02114, USA
Urol Oncol 28:268-73. 2010..We examined the influence of positive surgical margin status on fear of cancer recurrence in men undergoing radical prostatectomy... - Hospital surgical volume, utilization, costs and outcomes of retroperitoneal lymph node dissection for testis cancerHua yin Yu
Division of Urology, Brigham and Women s Hospital, Harvard Medical School, 1153 Centre Street, Suite 4420, Boston, MA 02130, USA
Adv Urol 2012:189823. 2012..However, most RPLND are performed at hospitals where there were two or fewer cases per year... - Use, costs and comparative effectiveness of robotic assisted, laparoscopic and open urological surgeryHua yin Yu
Division of Urology, Brigham and Women s Faulkner Hospital, Harvard Medical School, Boston, Massachusetts
J Urol 187:1392-8. 2012..We used a population based approach to assess use, costs and outcomes of robotic assisted laparoscopic surgery vs laparoscopic surgery and open surgery for common robotic assisted urological procedures... - Overcoming the learning curve for robotic-assisted laparoscopic radical prostatectomyMarcos P Freire
Division of Urology, Brigham and Women s Hospital, 45 Francis Street ASB II 3, Boston, MA 02115, USA
Urol Clin North Am 37:37-47, Table of Contents. 2010..This article describes the RALP learning curve, reviews in detail the challenging steps of the operation, describes the authors' RALP technique, and concludes with tips to overcome the learning curve... - Cancer control and functional outcomes of salvage radical prostatectomy for radiation-recurrent prostate cancer: a systematic review of the literatureDaher C Chade
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Eur Urol 61:961-71. 2012..Prostate cancer (PCa) recurrence following definitive radiation therapy (RT) remains a vexing challenge for the practicing physician. Salvage radical prostatectomy (SRP) has not been recognized yet as a valuable therapeutic option... - Robotic urethrovesical anastomosis: combining running and interrupted suturesAlexander M Berry
Division of Urology, Brigham and Women's Hospital, Boston, Massachusetts 02155, USA
J Endourol 22:2127-9. 2008 - Drug treatment of urological symptoms: estimating the magnitude of unmet need in a community-based sampleSusan A Hall
Division of Urologic Surgery, Brigham and Women s Hospital, Boston, MA, USA
BJU Int 104:1680-8. 2009.... - Improved survival with single-agent paclitaxel consolidation/maintenance therapy in advanced ovarian carcinomaJohn P Micha
Gynecologic Oncology Associates, Hoag Cancer Center and Women's Cancer Research Foundation, Newport Beach, CA 92663, USA
Oncology 71:49-53. 2006.... - Individual physician experience with laparoscopic supracervical hysterectomy in a single outpatient settingStephanie N McClellan
Newport Beach, California 92663, USA
Surg Innov 14:102-6. 2007..Optimal patient postoperative stay and a minimal complication rate suggest that this procedure performed at a single outpatient surgery center is feasible...