Research Topics
| Dina R Hirshfeld-BeckerSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
Applying cognitive-behavioral therapy for anxiety to the younger childDina R Hirshfeld-Becker
Child Cognitive Behavioral Therapy Program, Department of Psychiatry, Massachusetts General Hospital MGH, 55 Fruit Street, Boston, MA 02114, USA
Child Adolesc Psychiatr Clin N Am 20:349-68. 2011..The authors conclude with recommendations for future directions for research in this area...
Psychopathology in adolescent offspring of parents with panic disorder, major depression, or both: a 10-year follow-upDina R Hirshfeld-Becker
Department of Psychiatry, Massachusetts General Hospital, USA
Am J Psychiatry 169:1175-84. 2012..The authors examined the specificity and course of psychiatric disorders from early childhood through adolescence in offspring of parents with confirmed panic disorder and major depressive disorder...
Behavioral inhibition in preschool children at risk is a specific predictor of middle childhood social anxiety: a five-year follow-upDina R Hirshfeld-Becker
Harvard Medical School Massachusetts General Hospital, Boston, MA 02138, USA
J Dev Behav Pediatr 28:225-33. 2007..It has been hypothesized to be a risk factor for anxiety disorders. In this prospective longitudinal study, we compared the psychiatric outcomes in middle childhood of children evaluated at preschool age for BI...
Disruptive behavior disorders in offspring of parents with major depression: associations with parental behavior disordersDina R Hirshfeld-Becker
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, United States
J Affect Disord 111:176-84. 2008....
Laboratory-observed behavioral disinhibition in the young offspring of parents with bipolar disorder: a high-risk pilot studyDina R Hirshfeld-Becker
Mass General Hospital Pediatric Psychopharmacology Program, 185 Alewife Brook Parkway, Suite 2100, Cambridge, MA 02138, USA
Am J Psychiatry 163:265-71. 2006..This study tested whether behavioral disinhibition is more prevalent among offspring of parents with bipolar disorder than among offspring of parents without bipolar disorder...
Pregnancy complications associated with childhood anxiety disordersDina R Hirshfeld-Becker
Pediatric Psychopharmacology Program, Massachusetts General Hospital, Cambridge, Massachusetts 02138, USA
Depress Anxiety 19:152-62. 2004..Results suggest that prenatal stressors may increase a child's risk for anxiety disorders beyond the risk conferred by parental psychopathology alone...
High risk studies and developmental antecedents of anxiety disordersDina R Hirshfeld-Becker
MGH Clinical and Research Program in Pediatric Psychopharmacology, 185 Alewife Brook Parkway, Suite 2000, Cambridge, MA 02138, USA
Am J Med Genet C Semin Med Genet 148:99-117. 2008....
Lack of association between behavioral inhibition and psychosocial adversity factors in children at risk for anxiety disordersDina R Hirshfeld-Becker
Pediatric Psychopharmacology Unit, Department of Psychiatry, Massachusetts General Hospital, Cambridge, MA 02138, USA
Am J Psychiatry 161:547-55. 2004..To explore whether this association was mediated by environmental factors, the authors examined associations between psychosocial adversity variables and behavioral inhibition in this group of children...
Cognitive-behavioral intervention with young anxious childrenDina R Hirshfeld-Becker
Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA
Harv Rev Psychiatry 16:113-25. 2008....
Cognitive behavioral therapy for 4- to 7-year-old children with anxiety disorders: a randomized clinical trialDina R Hirshfeld-Becker
Massachusetts General Hospital, 185 Alewife Brook Parkway, Cambridge, MA 02138, USA
J Consult Clin Psychol 78:498-510. 2010..To examine the efficacy of a developmentally appropriate parent-child cognitive behavioral therapy (CBT) protocol for anxiety disorders in children ages 4-7 years...
Rationale and principles for early intervention with young children at risk for anxiety disordersDina R Hirshfeld-Becker
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, 02138, USA
Clin Child Fam Psychol Rev 5:161-72. 2002....
Clinical outcomes of laboratory-observed preschool behavioral disinhibition at five-year follow-upDina R Hirshfeld-Becker
Pediatric Psychopharmacology Program, Massachusetts General Hospital, 185 Alewife Brook Parkway, Cambridge, MA 02138, USA
Biol Psychiatry 62:565-72. 2007..In the present study, our objective was to examine the diagnostic outcome in middle childhood of behavioral disinhibition assessed at preschool age among offspring at risk for anxiety and mood disorders...
Developmental trajectories of anxiety disorders in offspring at high risk for panic disorder and major depressionJoseph Biederman
Massachusetts General Hospital, Pediatric Psychopharmacology Unit, Boston, MA 02114, USA
Psychiatry Res 153:245-52. 2007....
Does referral bias impact findings in high-risk offspring for anxiety disorders? A controlled study of high-risk children of non-referred parents with panic disorder/agoraphobia and major depressionJoseph Biederman
Pediatric Psychopharmacology Program and the Department of Psychiatry, Massachusetts General Hospital, Warren 705, 15 Parkman St, Boston, MA 02114, USA
J Affect Disord 82:209-16. 2004..This study evaluated whether these patterns of transmission between parents and high-risk offspring are moderated by referral bias...
A controlled longitudinal 5-year follow-up study of children at high and low risk for panic disorder and major depressionJoseph Biederman
Pediatric Psychopharmacology Program, Massachusetts General Hospital, Department of Psychiatry, Harvard Medical School, Boston, MA 02114, USA
Psychol Med 36:1141-52. 2006..To evaluate the longitudinal course of psychiatric disorders in children of parents with panic disorder (PD) and major depression (MD) as they transition through the period of risk from childhood into adolescence...
Psychopathology in the young offspring of parents with bipolar disorder: a controlled pilot studyDina R Hirshfeld-Becker
Pediatric Psychopharmacology Program, Massachusetts General Hospital, 185 Alewife Brook Parkway, Suite 2100, Cambridge, MA 02138, USA
Psychiatry Res 145:155-67. 2006..Results support the hypotheses of elevated behavior, anxiety, and mood disorders among offspring at risk for bipolar disorder, and suggest that this psychopathology is already evident in early childhood...
Antecedents to panic disorder in nonreferred adultsJoseph Biederman
Pediatric Psychopharmacology Clinic, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Clin Psychiatry 67:1179-86. 2006..The current study examined both childhood and adult comorbid disorders as potential antecedent disorders to panic disorder in a large sample of nonreferred adults...
Childhood antecedents to panic disorder in referred and nonreferred adultsJoseph Biederman
Pediatric Psychopharmacology Clinic, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Child Adolesc Psychopharmacol 15:549-61. 2005..We used a recursive partitioning method to examine antecedent childhood anxiety disorders in large samples of referred and nonreferred subjects with and without panic disorder...
Executive functioning in offspring at risk for depression and anxietyJamie A Micco
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, 85 Alewife Brook Parkway, Suite 2000, Cambridge, MA 02138, USA
Depress Anxiety 26:780-90. 2009..Studies of at-risk offspring can shed light on this question by examining whether EFDs characterize children at high risk for depression and anxiety who are not yet symptomatic...
Psychopathology in the offspring of parents with bipolar disorder: a controlled studyAude Henin
Pediatric Psychopharmacology Unit and Harvard Bipolar Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02138, USA
Biol Psychiatry 58:554-61. 2005..To examine the risk for psychopathology in offspring at risk for bipolar disorder and the course of psychiatric disorders in these youth...
The child behavior checklist broad-band scales predict subsequent psychopathology: A 5-year follow-upCarter R Petty
Massachusetts General Hospital, Pediatric Psychopharmacology Unit, Warren 705, 15 Parkman Street, Boston, MA 02114, USA
J Anxiety Disord 22:532-9. 2008..To evaluate the utility of the Child Behavior Check list (CBCL) for identifying children of parents with panic disorder or major depression at high-risk for future psychopathology...
Parental predictors of pediatric panic disorder/agoraphobia: a controlled study in high-risk offspringJoseph Biederman
Pediatric Psychopharmacology Clinic, Massachusetts General Hospital, Boston, 02114, USA
Depress Anxiety 22:114-20. 2005..These findings suggest that psychiatric comorbidity with other anxiety disorders and with bipolar disorder in parents with PD and their spouses confer a particularly high risk in their offspring to develop PD/AG in childhood...
Temperamental correlates of disruptive behavior disorders in young children: preliminary findingsDina R Hirshfeld-Becker
Pediatric Psychopharmacology Unit, Department of Psychiatry, Massachusetts General Hospital, Building 149, 13th Street, Boston, MA 02129, USA
Biol Psychiatry 51:563-74. 2002..Longitudinal studies using behavioral assessments of behavioral disinhibition are needed to confirm these findings...
Patterns of comorbidity in panic disorder and major depression: findings from a nonreferred sampleJoseph Biederman
Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston 02114, USA
Depress Anxiety 21:55-60. 2005....
Behavioral inhibition and disinhibition as hypothesized precursors to psychopathology: implications for pediatric bipolar disorderDina R Hirshfeld-Becker
Pediatric Psychopharmacology Program, Massachusetts General Hospital, Cambridge, Massacusetts 02138, USA
Biol Psychiatry 53:985-99. 2003....
Childhood antecedent disorders to bipolar disorder in adults: a controlled studyAude Henin
Pediatric Psychopharmacology Unit and Bipolar Clinic and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02138, United States
J Affect Disord 99:51-7. 2007..The aim of the study was to examine antecedent childhood psychiatric disorders in adult patients with bipolar disorder...
Posttraumatic stress disorder symptoms following media exposure to tragic events: impact of 9/11 on children at risk for anxiety disordersMichael W Otto
Massachusetts General Hospital and Harvard Medical School, MA, United States
J Anxiety Disord 21:888-902. 2007..Given the links between PTSD symptoms and viewing habits, parental monitoring of media exposure may be important for younger children...
Anxiety and depressive disorders in offspring at high risk for anxiety: a meta-analysisJamie A Micco
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital Harvard Medical School, Suite 2000, Cambridge, MA 02138, USA
J Anxiety Disord 23:1158-64. 2009..Results suggest that parental anxiety disorders confer significant risk for anxiety and depression in offspring. Additional studies are needed to examine whether there are differences among specific parental anxiety disorders...
Is psychopharmacologic treatment associated with neuropsychological deficits in bipolar youth?Aude Henin
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, 185 Alewife Brook Pkwy, Suite 2000, Cambridge, MA 02138, USA
J Clin Psychiatry 70:1178-85. 2009..To evaluate the impact of psychopharmacologic treatments on neuropsychological functioning in bipolar youth...
Anxiety is associated with impulsivity in bipolar disorderCharles T Taylor
Department of Psychiatry, Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
J Anxiety Disord 22:868-76. 2008..These data demonstrate that anxiety is positively associated with impulsivity in patients with BD. Further studies are needed to elucidate the implications of and reasons for this association...
Familial and temperamental risk factors for social anxiety disorderDina R Hirshfeld-Becker
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, MA, USA
New Dir Child Adolesc Dev 2010:51-65. 2010....
Moderating effects of major depression on patterns of comorbidity in patients with panic disorderJoseph Biederman
Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, and Harvard Medical School, WACC 725, 15 Parkman Street, Boston, MA 02114, USA
Psychiatry Res 126:143-9. 2004..Overanxious disorder was associated with both panic disorder and major depression. Major depression has important moderating effects on patterns of comorbidity of panic disorder in referred adults...
Effects of parental anxiety disorders in children at high risk for panic disorder: a controlled studyJoseph Biederman
Massachusetts General Hospital, Pediatric Psychopharmacology Research, Boston, MA 02114, United States
J Affect Disord 94:191-7. 2006..To examine the association between anxiety disorders in parents and offspring in a sample of children at risk for panic disorder. We hypothesized that individual anxiety disorders will breed true in offspring...
Behavioral inhibitionDina R Hirshfeld-Becker
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
Depress Anxiety 25:357-67. 2008....
Academic women faculty: are they finding the mentoring they need?Emily A Blood
Division of Adolescent Medicine, Boston Children s Hospital, Boston, MA 02115, USA
J Womens Health (Larchmt) 21:1201-8. 2012..Lack of effective mentoring may contribute to this disparity. We examined the role of academic rank, research focus, parenting, and part-time work on mentoring importance, needs, and gaps...
The corticotropin-releasing hormone gene and behavioral inhibition in children at risk for panic disorderJordan W Smoller
Department of Psychiatry, Massachusetts General Hospital, Boston 02114, USA
Biol Psychiatry 57:1485-92. 2005..To evaluate this further, we genotyped additional families for this marker and a panel of markers encompassing the CRH locus...
Association of a genetic marker at the corticotropin-releasing hormone locus with behavioral inhibitionJordan W Smoller
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Biol Psychiatry 54:1376-81. 2003..Transgenic mice overexpressing CRH exhibit BI-like behaviors, implicating this gene in the development of the phenotype...
Influence of RGS2 on anxiety-related temperament, personality, and brain functionJordan W Smoller
Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Arch Gen Psychiatry 65:298-308. 2008..The gene encoding regulator of G protein signaling 2 (Rgs2) is a quantitative trait gene that influences mouse anxiety behavior, making its human ortholog (RGS2) a compelling candidate gene for human anxiety phenotypes...
The developmental psychopathology of social anxiety disorderThomas H Ollendick
Child Study Center, Department of Psychology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0436, USA
Biol Psychiatry 51:44-58. 2002..Finally, we propose studies to test the viability of the developmental psychopathology model in understanding SAD...
Research Grants
- Study of Young Children at Risk for Depression and ADHDDina Hirshfeld Becker; Fiscal Year: 2005....
- Risk Factors for Adverse Outcome in Young Offspring of Bipolar ParentsDina Hirshfeld Becker; Fiscal Year: 2007....
- INTERVENTION FOR CHILDREN AT RISK FOR ANXIETY DISORDERSDina Hirshfeld Becker; Fiscal Year: 2002....
- Risk Factors for Adverse Outcome in Young Offspring of Bipolar ParentsDina R Hirshfeld Becker; Fiscal Year: 2010....
