Korie E HandwergerSummaryAffiliation: Massachusetts Institute of Technology Country: USA Publications
Research Grants
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Publications
Subnuclear organelles: new insights into form and functionKorie E Handwerger
Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, MA 02142, USA
Trends Cell Biol 16:19-26. 2006..We discuss how these findings impact our understanding of the guiding principles of nuclear organization and various types of human disease...
Cajal bodies, nucleoli, and speckles in the Xenopus oocyte nucleus have a low-density, sponge-like structureKorie E Handwerger
Department of Embryology, Carnegie Institution of Washington, Baltimore, MD 21210, USA
Mol Biol Cell 16:202-11. 2005..Together, the interferometry and dextran penetration data show that organelles in the Xenopus GV have a low-density, sponge-like structure that provides access to macromolecules from the nucleoplasm...
Heat shock induces mini-Cajal bodies in the Xenopus germinal vesicleKorie E Handwerger
Department of Embryology, Carnegie Institution of Washington, 115 West University Parkway, Baltimore, MD 21210, USA
J Cell Sci 115:2011-20. 2002..We suggest that Cajal bodies originate by self-organization of preformed components, preferentially on the surface of B-snurposomes...
Steady-state dynamics of Cajal body components in the Xenopus germinal vesicleKorie E Handwerger
Department of Embryology, Carnegie Institution of Washington, Baltimore, MD 21210, USA
J Cell Biol 160:495-504. 2003..We propose that binding to other molecules and possibly assembly into larger complexes are the rate-limiting steps for FRAP of U7, coilin, and TBP inside CBs...
Research Grants
- Prion-Based Mechanisms in Metazoan DevelopmentKORIE HANDWERGER; Fiscal Year: 2006..Finally, CePrDps will be examined for their ability to regulate development in the absence of their putative prion domains. ..
