Research Topics
Species | Mehra GolshanSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
| Collaborators
|
Detail Information
Publications
Breast conservation for male breast carcinomaMehra Golshan
Department of Surgery, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Breast 16:653-6. 2007..Breast-conserving surgery in male breast cancer patients should be considered an option in patients without overt nipple/areolar involvement...
The effect of ipsilateral whole breast ultrasonography on the surgical management of breast carcinomaMehra Golshan
Department of Surgery, Lynn Sage Breast Center, Northwestern University, 251 East Huron St, Galter 13 174, Chicago, IL 60611, USA
Am J Surg 186:391-6. 2003..Whole breast ultrasonography has been shown to identify lesions not seen on mammography. This study sought to determine how often whole breast ultrasonography changes the surgical management of breast cancer...
Metaplastic carcinoma of the breast with neuroglial differentiationMehra Golshan
Department of Surgery Brigham and Women s Hospital 75 Francis Street, Boston, MA, 02115 USA
Breast 15:545-9. 2006..Subsequent therapy consisted of standard adjuvant breast cancer chemotherapy and radiation therapy...
Does neoadjuvant bevacizumab increase surgical complications in breast surgery?M Golshan
Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
Ann Surg Oncol 18:733-7. 2011..There are limited data on the safety of bevacizumab (bev) in the neoadjuvant setting. We sought to explore the safety of neoadjuvant cisplatin/bev in a protocol for triple negative breast cancer (TNBC)...
The prevalence of germline BRCA1 and BRCA2 mutations in young women with breast cancer undergoing breast-conservation therapyMehra Golshan
Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
Am J Surg 192:58-62. 2006..We sought to determine the frequency of BRCA1/BRCA2 mutations in women who underwent BCT. Genetic testing results were compared with the prior probability of mutations in either gene...
Can methylene blue only be used in sentinel lymph node biopsy for breast cancer?Mehra Golshan
Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Breast J 12:428-30. 2006..In experienced hands, methylene blue alone is a highly sensitive method of detecting SLNs. Avoiding the greater frequency of allergic reactions seen with lymphazurin is an important advantage of methylene blue...
Prevention and management of arm lymphedema in the patient with breast cancerMehra Golshan
Department of Surgery, Brigham and Women s Hospital and the Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
J Support Oncol 4:381-6. 2006..The increasing number of breast cancer survivors and the high prevalence of the disease will continue to make lymphedema a significant consequence of breast cancer treatment...
Nomogram for the prediction of having four or more involved nodes for sentinel lymph node-positive breast cancerAngela Katz
Department of Radiation Oncology, Massachusetts General Hospital, 100 Blossom St, Cox 301, Boston, MA 02114, USA
J Clin Oncol 26:2093-8. 2008..The purpose of this study was to define possible predictors of having four or more involved nodes to provide information for clinicians and patients making decisions about adjuvant chemotherapy and radiation...
Can breast MRI predict axillary lymph node metastasis in women undergoing neoadjuvant chemotherapySara Javid
Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, USA
Ann Surg Oncol 17:1841-6. 2010....
Can axillary node dissection be omitted in a subset of patients with low local and regional failure rates?Christina Barkley
Department of Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Breast J 18:23-7. 2012..In this highly selected group of patients who had a positive SLNB but did not undergo cALND, we observed no axillary recurrences...
Physical activity behaviors in women with newly diagnosed ductal carcinoma-in-situJennifer A Ligibel
Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
Ann Surg Oncol 16:106-12. 2009..Women who underwent mastectomy, as well as women who were more anxious, were more likely to decrease their level of physical activity. Women with DCIS might benefit from targeted interventions to increase physical activity...
Internal mammary nodes in breast cancer: diagnosis and implications for patient management -- a systematic reviewRonald C Chen
Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
J Clin Oncol 26:4981-9. 2008..However, even in patients with visualized primary IMN drainage, the potential benefit of treatment should be balanced against the risk of added morbidity...
Impact of neoadjuvant chemotherapy on breast reconstructionYue Yung Hu
Center for Surgery and Public Health, Department of Surgery, Brigham and Women s Hospital, Boston, Massachusetts, USA
Cancer 117:2833-41. 2011..Multiple studies have confirmed the safety of both chemotherapy before breast surgery and immediate reconstruction. Little has been written about the effect of neoadjuvant chemotherapy on decisions about reconstruction...
Diminishing morbidity with the increased use of sentinel node biopsy in breast carcinomaAndrea Bafford
Department of Surgery, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA, USA
Am J Surg 200:374-7. 2010..The aim of this study was to compare the morbidity of sentinel node biopsy only, sentinel node biopsy followed by axillary dissection, and axillary node dissection only...
Breast surgery in stage IV breast cancer: impact of staging and patient selection on overall survivalAndrea C Bafford
Brigham and Women s Hospital, Boston, MA 02115, USA
Breast Cancer Res Treat 115:7-12. 2009..Retrospective analyses suggest patients with stage IV breast cancer who undergo breast surgery have improved survival. We sought to determine whether surgery and other clinical and staging factors affected overall survival...
Current surgical approach to Paget's diseaseLaura S Dominici
Department of Surgical Oncology, Brigham and Women s Hospital Dana Farber Cancer Institute, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
Am J Surg 204:18-22. 2012..Paget's disease constitutes between 1% and 3% of all breast malignancies, which makes defining standard surgical therapy difficult. We sought to identify preoperative factors that would select patients for successful breast conservation...
Tubular carcinoma of the breast: results of a large contemporary seriesSara H Javid
Department of Surgery, Brigham and Women s Hospital Dana Farber Cancer Institute, Boston, MA 02115, USA
Am J Surg 197:674-7. 2009..Tubular carcinoma (TC) of the breast is an uncommon subtype associated with a favorable prognosis. This study aimed to assess recent trends and prognostic features in the treatment of TC...
Perceptions and management approaches of physicians who care for women with ductal carcinoma in situAnn Partridge
Dana Farber Cancer Institute, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Clin Breast Cancer 8:275-80. 2008..We sought in a longitudinal cohort study of women with DCIS to assess the attitudes and management approaches toward DCIS among physicians who provide care to women...
Surgical margins and the risk of local-regional recurrence after mastectomy without radiation therapyStephanie K Childs
Harvard Radiation Oncology Program, Boston, Massachusetts, USA
Int J Radiat Oncol Biol Phys 84:1133-8. 2012..We sought to clarify the influence of the mastectomy margin on the risk of LRR...
Surgery of the primary tumor does not improve survival in stage IV breast cancerLaura Dominici
Department of Surgical Oncology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA, 02115, USA
Breast Cancer Res Treat 129:459-65. 2011..94, CI 0.83-1.08, P=0.38). When matching for the variables associated with a survival benefit in previous studies, surgery was not shown to improve survival in the stage IV setting for this subset...
Is axillary dissection needed in node-positive breast cancer?Caprice C Greenberg
Department of Surgery, Brigham and Women s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
Expert Rev Anticancer Ther 8:195-8. 2008..We review the literature available and discuss future directions in identifying a subgroup who may avoid an ALND...
Breast MRI wire-guided excisional biopsy: specimen size as compared to mammogram wire-guided excisional biopsy and implications for useSara H Javid
Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
Ann Surg Oncol 14:3352-8. 2007..We hypothesized that more tissue would be resected with MRIbx compared to Mammobx. We also sought to evaluate factors that might predict the presence of breast cancer in patients undergoing MRIbx...
Mucinous breast carcinoma: a large contemporary seriesChristina R Barkley
Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
Am J Surg 196:549-51. 2008..Mucinous breast cancer is typically associated with a favorable prognosis. This study aimed to assess recent trends and prognostic features in the treatment of mucinous breast carcinoma...
Does MRI predict pathologic tumor response in women with breast cancer undergoing preoperative chemotherapy?Davendra Segara
Department of Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Surg Oncol 96:474-80. 2007..The purpose of this study is to review imaging studies performed in patients who received preoperative chemotherapy prior to surgery and determine whether MRI, ultrasound (US) or physical exam best predicted final pathologic tumor size...
Sentinel node biopsy is important in mastectomy for ductal carcinoma in situFrancisco J Dominguez
Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Ann Surg Oncol 15:268-73. 2008..There is uncertainty about the utility of sentinel node biopsy (SNB) for ductal carcinoma in situ (DCIS) and its potential to avoid axillary lymph node dissection (ALND) in patients undergoing mastectomy for DCIS...
Management of intraductal papillomas of the breast: an analysis of 129 cases and their outcomeNasim Ahmadiyeh
Department of Surgery, Brigham and Women s Hospital and the Dana Farber Cancer Institute, Boston, MA, USA
Ann Surg Oncol 16:2264-9. 2009..The management of intraductal papillomas of the breast has been controversial; some advocate surgical excision of all lesions despite benign pathologic features, whereas others excise only those specimens with atypia...
Sentinel lymph node biopsy in men with breast cancer: a report of 31 consecutive procedures and review of the literatureJennifer E Rusby
Massachusetts General Hospital, Boston, MA, USA
Clin Breast Cancer 7:406-10. 2006..CONCLUSION: The high rate of lymph node-positive disease, even in this series of patients with clinically node-negative disease, reflects the later presentation of breast cancer in men...
Use of tumescent mastectomy technique as a risk factor for native breast skin flap necrosis following immediate breast reconstructionYoon S Chun
Department of Surgery, Brigham and Women s Hospital, Faulkner Hospital, Boston, MA, USA
Am J Surg 201:160-5. 2011..This study was performed to determine whether the technique increases the risk for skin flap necrosis in an immediate breast reconstruction setting...
Risk perceptions and psychosocial outcomes of women with ductal carcinoma in situ: longitudinal results from a cohort studyAnn Partridge
Dana Farber Cancer Institute, Brigham and Women s Hospital, Harvard Medical School, 44 Binney St, Boston, MA 02115, USA
J Natl Cancer Inst 100:243-51. 2008..Preliminary studies have suggested that women with DCIS may overestimate their risk of disease recurrence. Few data exist regarding psychosocial outcomes for women with DCIS...
MRI-directed, wire-localized breast excisions: incidence of malignancy and recommendations for pathologic evaluationJoseph W Carlson
Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
Hum Pathol 38:1754-9. 2007..This study demonstrates that gross examination and specimen radiography do not identify most of the malignancies in MRI-localized biopsies and, therefore, optimal processing requires complete microscopic examination of these specimens...
Sentinel lymph node biopsy lowers the rate of lymphedema when compared with standard axillary lymph node dissectionMehra Golshan
Department of Surgery, Rush University, Rush Presbyterian St. Luke's Medical Center, Chicago, Illinois, USA
Am Surg 69:209-11; discussion 212. 2003..This has an important impact on long-term postoperative management of patients with breast cancer...
Sentinel lymph node biopsy for occult breast cancer detected during breast reduction surgeryMehra Golshan
Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Am Surg 72:397-400. 2006..Reconstruction was possible in five of six patients. Sentinel lymph node biopsy should not be considered a contraindication after breast reduction surgery...
Microinvasive breast cancer: ER, PR, and HER-2/neu status and clinical outcomes after breast-conserving therapy or mastectomyDanielle N Margalit
Department of Radiation Oncology, Brigham and Women s Hospital Dana Farber Cancer Institute, Boston, MA, USA
Ann Surg Oncol 20:811-8. 2013..We document the immunophenotype, incidence of axillary metastases, and rate of recurrence in a well-defined case series...
Paget disease of the breast with invasion from nipple skin into the dermis: an unusual type of skin invasion not associated with an adverse outcomeMary Ann Sanders
Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, Kentucky, USA
Arch Pathol Lab Med 137:72-6. 2013..In very rare cases, tumor cells within the epidermis invade through the basement membrane of the skin into the dermis...
Can axillary lymph node dissection be omitted in patients with breast cancer and positive sentinel nodes?L Dominici
Department of Surgery, Brigham and Women s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
Minerva Chir 65:547-54. 2010..This article reviews the literature related to this controversial and evolving topic...
