ALLAN GOLDSTEIN

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi Enteric nervous system patterning in the avian hindgut
    Adele M Doyle
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Dev Dyn 229:708-12. 2004
  2. ncbi Intestinal coelomic transplants: a novel method for studying enteric nervous system development
    Nandor Nagy
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Cell Tissue Res 326:43-55. 2006
  3. ncbi BMP signaling is necessary for neural crest cell migration and ganglion formation in the enteric nervous system
    Allan M Goldstein
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Mech Dev 122:821-33. 2005
  4. ncbi A bird's eye view of enteric nervous system development: lessons from the avian embryo
    Allan M Goldstein
    Department of Pediatric Surgery and the Pediatric Intestinal Rehabilitation Program, Harvard Medical School, Boston, Massachusetts 02114, USA
    Pediatr Res 64:326-33. 2008
  5. ncbi Pelvic plexus contributes ganglion cells to the hindgut enteric nervous system
    Nandor Nagy
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Dev Dyn 236:73-83. 2007
  6. ncbi BMPRIA is a promising marker for evaluating ganglion cells in the enteric nervous system--a pilot study
    Katherine C Brewer
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Hum Pathol 36:1120-6. 2005
  7. ncbi Endothelin-3 regulates neural crest cell proliferation and differentiation in the hindgut enteric nervous system
    Nandor Nagy
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Warren 1153, Boston, MA 02114, USA
    Dev Biol 293:203-17. 2006
  8. ncbi Endothelial cells promote migration and proliferation of enteric neural crest cells via beta1 integrin signaling
    Nandor Nagy
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Dev Biol 330:263-72. 2009
  9. ncbi Hydrocortisone modulates cholera toxin endocytosis by regulating immature enterocyte plasma membrane phospholipids
    Lei Lu
    Developmental Gastroenterology Laboratory, Massachusetts General Hospital for Children, Boston, Massachusetts, USA
    Gastroenterology 135:185-193.e1. 2008
  10. ncbi Bone morphogenetic protein signaling pathway plays multiple roles during gastrointestinal tract development
    Pascal de Santa Barbara
    Institut de Genetique Humaine, UPR 1142 CNRS, Montpellier, France
    Dev Dyn 234:312-22. 2005

Research Grants

  1. BMP signaling in enteric nervous system development
    ALLAN GOLDSTEIN; Fiscal Year: 2007
  2. Gdnf and endothelin-3 regulate colorectal enteric nervous system development
    Allan M Goldstein; Fiscal Year: 2010

Collaborators

Detail Information

Publications10

  1. ncbi Enteric nervous system patterning in the avian hindgut
    Adele M Doyle
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Dev Dyn 229:708-12. 2004
    ..Detailed understanding of normal avian hindgut ENS development will allow better utilization of this model system to study abnormalities of the intestinal nervous system...
  2. ncbi Intestinal coelomic transplants: a novel method for studying enteric nervous system development
    Nandor Nagy
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Cell Tissue Res 326:43-55. 2006
    ..We discuss the advantages of intestinal coelomic transplants for studying ENS development...
  3. ncbi BMP signaling is necessary for neural crest cell migration and ganglion formation in the enteric nervous system
    Allan M Goldstein
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Mech Dev 122:821-33. 2005
    ..Our results support an essential role for BMP signaling in these aspects of ENS development and provide a basis for further investigation of these proteins in the etiology of neuro-intestinal disorders...
  4. ncbi A bird's eye view of enteric nervous system development: lessons from the avian embryo
    Allan M Goldstein
    Department of Pediatric Surgery and the Pediatric Intestinal Rehabilitation Program, Harvard Medical School, Boston, Massachusetts 02114, USA
    Pediatr Res 64:326-33. 2008
    ..The strengths and versatility of the avian embryo continue to make it a valuable experimental system for studying the development of the ENS...
  5. ncbi Pelvic plexus contributes ganglion cells to the hindgut enteric nervous system
    Nandor Nagy
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Dev Dyn 236:73-83. 2007
    ..These results demonstrate that the pelvic plexus, and not the NoR, serves as the staging area for sacral crest-derived cells to enter the avian hindgut, confirming the evolutionary conservation of this important embryologic process...
  6. ncbi BMPRIA is a promising marker for evaluating ganglion cells in the enteric nervous system--a pilot study
    Katherine C Brewer
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Hum Pathol 36:1120-6. 2005
    ..We propose that BMPRIA immunohistochemistry may be a promising new tool for the identification of enteric ganglion cells in the evaluation of patients with neurointestinal disorders...
  7. ncbi Endothelin-3 regulates neural crest cell proliferation and differentiation in the hindgut enteric nervous system
    Nandor Nagy
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Warren 1153, Boston, MA 02114, USA
    Dev Biol 293:203-17. 2006
    ..Our results demonstrate multiple roles for ET3 signaling during ENS development in the avian hindgut, where it influences NCC proliferation, differentiation, and migration...
  8. ncbi Endothelial cells promote migration and proliferation of enteric neural crest cells via beta1 integrin signaling
    Nandor Nagy
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Dev Biol 330:263-72. 2009
    ..These interactions may play an important role in guiding migration and patterning in the developing ENS...
  9. ncbi Hydrocortisone modulates cholera toxin endocytosis by regulating immature enterocyte plasma membrane phospholipids
    Lei Lu
    Developmental Gastroenterology Laboratory, Massachusetts General Hospital for Children, Boston, Massachusetts, USA
    Gastroenterology 135:185-193.e1. 2008
    ..Our aim was to characterize the developmental difference in cholera toxin (CT)-GM1-mediated endocytosis...
  10. ncbi Bone morphogenetic protein signaling pathway plays multiple roles during gastrointestinal tract development
    Pascal de Santa Barbara
    Institut de Genetique Humaine, UPR 1142 CNRS, Montpellier, France
    Dev Dyn 234:312-22. 2005
    ..These results demonstrate that BMP signaling is activated in all the tissue layers of the GI tract during the development and plays a role during interactions and reciprocal communications of these tissue layers...

Research Grants4

  1. BMP signaling in enteric nervous system development
    ALLAN GOLDSTEIN; Fiscal Year: 2007
    ....
  2. Gdnf and endothelin-3 regulate colorectal enteric nervous system development
    Allan M Goldstein; Fiscal Year: 2010
    ..The goal of this proposal is to understand the mechanisms that control development of the intestinal nervous system in order to improve our ability to diagnose and treat children born with these chronic and disabling conditions. ..