J N Glickman

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Interinstitutional variability and effect of tissue fixative on the interpretation of a Barrett cytokeratin 7/20 immunoreactivity pattern in Barrett esophagus
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Hum Pathol 36:58-65. 2005
  2. pmc Multilayered epithelium in a rat model and human Barrett's esophagus: similar expression patterns of transcription factors and differentiation markers
    Xiaoxin Chen
    Cancer Research Program, Julius L, Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, 700 George Street, Durham, NC 27707, USA
    BMC Gastroenterol 8:1. 2008
  3. pmc Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp and sessile serrated polyp/adenoma
    Takako Kawasaki
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    BMC Cancer 8:33. 2008
  4. ncbi request reprint Mucin core peptide expression can help differentiate Barrett's esophagus from intestinal metaplasia of the stomach
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Am J Surg Pathol 27:1357-65. 2003
  5. ncbi request reprint Mucin core polypeptide expression in the progression of neoplasia in Barrett's esophagus
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Hum Pathol 37:1304-15. 2006
  6. ncbi request reprint Pediatric patients with untreated ulcerative colitis may present initially with unusual morphologic findings
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Am J Surg Pathol 28:190-7. 2004
  7. ncbi request reprint Gastritis
    J N Glickman
    Department of Pathology, Brigham and Women s Hospital and Harvard University School of Medicine, Boston, Massachusetts 02115, USA
    Gastrointest Endosc Clin N Am 11:717-40, vii. 2001
  8. ncbi request reprint Morphology of the cardia and significance of carditis in pediatric patients
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Surg Pathol 26:1032-9. 2002
  9. ncbi request reprint Phenotypic characteristics of a distinctive multilayered epithelium suggests that it is a precursor in the development of Barrett's esophagus
    J N Glickman
    Departments of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Surg Pathol 25:569-78. 2001
  10. ncbi request reprint Phenotype of Barrett's esophagus and intestinal metaplasia of the distal esophagus and gastroesophageal junction: an immunohistochemical study of cytokeratins 7 and 20, Das-1 and 45 MI
    J N Glickman
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Am J Surg Pathol 25:87-94. 2001

Detail Information

Publications59

  1. ncbi request reprint Interinstitutional variability and effect of tissue fixative on the interpretation of a Barrett cytokeratin 7/20 immunoreactivity pattern in Barrett esophagus
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Hum Pathol 36:58-65. 2005
    ..Nevertheless, specific criteria for interpretation of CK7/20 staining can be successfully applied between institutions and need to be developed before use of this technique in clinical practice...
  2. pmc Multilayered epithelium in a rat model and human Barrett's esophagus: similar expression patterns of transcription factors and differentiation markers
    Xiaoxin Chen
    Cancer Research Program, Julius L, Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, 700 George Street, Durham, NC 27707, USA
    BMC Gastroenterol 8:1. 2008
    ..Invest. 2004;84:753-765). The purpose of this study was to compare the phenotype of rat MLE with human MLE, in order to gain insight into the nature of MLE and its potential role in the development of BE...
  3. pmc Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp and sessile serrated polyp/adenoma
    Takako Kawasaki
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    BMC Cancer 8:33. 2008
    ..Therefore, we hypothesized that COX-2 may play a less important role in the serrated pathway...
  4. ncbi request reprint Mucin core peptide expression can help differentiate Barrett's esophagus from intestinal metaplasia of the stomach
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Am J Surg Pathol 27:1357-65. 2003
    ..Columnar epithelium in the "normal" gastric cardia has a partially intestinalized phenotype and, as a result, may represent an early form of metaplastic epithelium...
  5. ncbi request reprint Mucin core polypeptide expression in the progression of neoplasia in Barrett's esophagus
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Hum Pathol 37:1304-15. 2006
    ..Alterations in MUC expression occur in the progression of dysplasia in BE. However, none of these markers helps identify a subgroup of patients at increased risk for neoplasia...
  6. ncbi request reprint Pediatric patients with untreated ulcerative colitis may present initially with unusual morphologic findings
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Am J Surg Pathol 28:190-7. 2004
    ..Therefore, the objectives of this study were to determine the clinical and pathologic features of new-onset UC in children and to compare the initial presentation of UC in this group with a control group of adults...
  7. ncbi request reprint Gastritis
    J N Glickman
    Department of Pathology, Brigham and Women s Hospital and Harvard University School of Medicine, Boston, Massachusetts 02115, USA
    Gastrointest Endosc Clin N Am 11:717-40, vii. 2001
    ..Other major causes of gastritis include celiac disease, allergic disorders, and Crohn's disease. The distinctive clinical, endoscopic, and histologic features of these disorders are discussed...
  8. ncbi request reprint Morphology of the cardia and significance of carditis in pediatric patients
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Surg Pathol 26:1032-9. 2002
    ....
  9. ncbi request reprint Phenotypic characteristics of a distinctive multilayered epithelium suggests that it is a precursor in the development of Barrett's esophagus
    J N Glickman
    Departments of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Surg Pathol 25:569-78. 2001
    ..The mucosal gland duct epithelium may contain progenitor cells that can give rise to ME...
  10. ncbi request reprint Phenotype of Barrett's esophagus and intestinal metaplasia of the distal esophagus and gastroesophageal junction: an immunohistochemical study of cytokeratins 7 and 20, Das-1 and 45 MI
    J N Glickman
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Am J Surg Pathol 25:87-94. 2001
    ..This may indicate that IM in LSBE, SSBE and at the GEJ have similar biologic properties. Based on our data, SSBE and IMGEJ cannot be distinguished on the basis of their immunophenotype...
  11. pmc Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma
    Gavin J Gordon
    Department of Surgery, Division of Thoracic Surgery, Harvard Medical School and Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    J Natl Cancer Inst 101:678-86. 2009
    ..In this study, we investigated the predictive value and technical assay performance of this test in patients with malignant pleural mesothelioma...
  12. ncbi request reprint Expression of p53-related protein p63 in the gastrointestinal tract and in esophageal metaplastic and neoplastic disorders
    J N Glickman
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Hum Pathol 32:1157-65. 2001
    ..These data also indicate that multilayered epithelium is phenotypically similar to, and may share a lineage relationship with, mucosal gland duct epithelium...
  13. ncbi request reprint An unusual mixed tumor of the pancreas: sonographic and MDCT features
    Koenraad J Mortele
    Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    JOP 10:204-8. 2009
    ..Mixed tumors of the pancreas are exceedingly rare...
  14. pmc Transcriptome sequencing of malignant pleural mesothelioma tumors
    David J Sugarbaker
    International Mesothelioma Program, Division of Thoracic Surgery, Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 105:3521-6. 2008
    ..Of the seven point mutations, three were observed in at least one tumor from 49 other MPM patients. The mutations were in genes that could be causally related to cancer and included XRCC6, PDZK1IP1, ACTR1A, and AVEN...
  15. ncbi request reprint Computed tomography features of nonalcoholic steatohepatitis with histopathologic correlation
    M Raquel Oliva
    Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Comput Assist Tomogr 30:37-43. 2006
    ..This study was conducted to describe the computed tomography (CT) features of nonalcoholic steatohepatitis (NASH) and to evaluate if the CT features could be used to diagnose and stage NASH...
  16. doi request reprint Renal cell carcinoma: t1 and t2 signal intensity characteristics of papillary and clear cell types correlated with pathology
    M Raquel Oliva
    Department of Radiology, Brigham and Women s Hospital, Boston, MA 02115, USA
    AJR Am J Roentgenol 192:1524-30. 2009
    ..The objective of our study was to describe the T1 and T2 signal intensity characteristics of papillary renal cell carcinoma (RCC) and clear cell RCC with pathologic correlation...
  17. pmc Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling
    Gavin J Gordon
    Thoracic Surgery Oncology Laboratory, Division of Thoracic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Pathol 166:1827-40. 2005
    ..Finally, we used bioinformatics tools (ie, software) to create and explore complex physiological pathways. Combined, all of these data may advance our understanding of mesothelioma tumorigenesis, pathobiology, or both...
  18. pmc Validation of genomics-based prognostic tests in malignant pleural mesothelioma
    Gavin J Gordon
    Thoracic Surgery Oncology Laboratory and Division of Thoracic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Clin Cancer Res 11:4406-14. 2005
    ..In this report, we examine the accuracy of a previously proposed prognostic test in an independent cohort of MPM patients. This test uses simple ratios of gene expression levels to provide a novel prognostication scheme...
  19. ncbi request reprint Brenner tumors of the ovary: sonographic and computed tomographic imaging features
    Gretchen E Green
    Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    J Ultrasound Med 25:1245-51; quiz 1252-4. 2006
    ..The purpose of this study was to describe the sonographic appearance of ovarian Brenner tumors with computed tomographic (CT) correlation...
  20. ncbi request reprint Morphologic features are useful in distinguishing Barrett esophagus from carditis with intestinal metaplasia
    Amitabh Srivastava
    Department of Pathology, Brigham and Women s Hospital, Boston, MA 02114, USA
    Am J Surg Pathol 31:1733-41. 2007
    ..Larger prospective studies need to be performed to validate these findings and evaluate the reproducibility of this approach in routine clinical practice...
  21. ncbi request reprint CT and MRI features of pure acinar cell carcinoma of the pancreas in adults
    Servet Tatli
    Department of Radiology, Division of Abdominal Imaging and Intervention, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    AJR Am J Roentgenol 184:511-9. 2005
    ..We sought to describe the CT and MRI features of pure acinar cell carcinoma of the pancreas in adults...
  22. ncbi request reprint Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF)
    Maina Lepourcelet
    Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Development 132:415-27. 2005
    ..Our findings also advance understanding of HDGF functions and implicate this developmentally regulated gene in RNA metabolic pathways that may influence malignant behaviors in colorectal cancer...
  23. doi request reprint Pancreatic intraductal papillary mucinous neoplasms: role of CT in predicting pathologic subtypes
    Rahul Gupta
    Department of Radiology, Division of Abdominal Imaging and Intervention, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    AJR Am J Roentgenol 191:1458-64. 2008
    ..The objective of our study was to evaluate whether CT can be used to predict the pathologic subtypes of pancreatic intraductal papillary mucinous neoplasms (IPMNs)...
  24. ncbi request reprint Pathologic features of reflux and Helicobacter pylori-associated carditis: a comparative study
    Tad J Wieczorek
    Department of Pathology, Brigham and Women s Hospital, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Surg Pathol 27:960-8. 2003
    ....
  25. ncbi request reprint Comparison of thyroid transcription factor-1 and hepatocyte antigen immunohistochemical analysis in the differential diagnosis of hepatocellular carcinoma, metastatic adenocarcinoma, renal cell carcinoma, and adrenal cortical carcinoma
    Tad J Wieczorek
    Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Am J Clin Pathol 118:911-21. 2002
    ..Thus, these markers are usefulfor the characterization of HCC in tissue sections and cell blocks and are highly effective for distinguishing these tumors from other neoplasms included in the differential diagnosis...
  26. ncbi request reprint CT findings in isolated ischemic proctosigmoiditis
    Walter Wiesner
    Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Eur Radiol 12:1762-7. 2002
    ....
  27. doi request reprint Multilayered epithelium in mucosal biopsy specimens from the gastroesophageal junction region is a histologic marker of gastroesophageal reflux disease
    Jonathan N Glickman
    Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
    Am J Surg Pathol 33:818-25. 2009
    ....
  28. pmc Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cell Host Microbe 8:292-300. 2010
    ..Cross-fostering experiments indicated a role for these organisms in maternal transmission of disease. Our findings illustrate how gut microbial communities work in concert with specific culturable colitogenic agents to cause IBD...
  29. ncbi request reprint Pancreatoblastoma in an adult woman: sonography, CT, and dynamic gadolinium-enhanced MRI features
    Joshua L Rosebrook
    Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    AJR Am J Roentgenol 184:S78-81. 2005
  30. pmc Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cell 131:33-45. 2007
    ..These findings reveal a novel function for T-bet as a peacekeeper of host-commensal relationships and provide new perspectives on the pathophysiology of IBD...
  31. pmc Acute appendicitis is characterized by a uniform and highly selective pattern of inflammatory gene expression
    C G Murphy
    Division of Emergency Medicine, Children s Hospital, Boston, Massachusetts, USA
    Mucosal Immunol 1:297-308. 2008
    ....
  32. ncbi request reprint Pneumatosis intestinalis and portomesenteric venous gas in intestinal ischemia: correlation of CT findings with severity of ischemia and clinical outcome
    W Wiesner
    Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    AJR Am J Roentgenol 177:1319-23. 2001
    ..The clinical outcome of patients with bowel ischemia with these CT findings seems to depend mainly on the severity and extent of their underlying disease...
  33. ncbi request reprint Expression patterns of inhibitor of apoptosis proteins in malignant pleural mesothelioma
    G J Gordon
    The Thoracic Surgery Oncology Laboratory and the Division of Thoracic Surgery, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    J Pathol 211:447-54. 2007
    ..Only IAP-1 and livin protein was expressed in the nucleus of MPM tumours. These results provide the rationale for additional study of this gene family in MPM and cancer in general...
  34. ncbi request reprint Gangliocytoma masquerading as a prolactinoma. Case report
    K C McCowen
    Harvard Vanguard Medical Associates, Boston, Massachusetts, USA
    J Neurosurg 91:490-5. 1999
    ..Furthermore, in such instances, consideration should be given to "obtaining a biopsy sample prior to electing for radiotherapy...
  35. pmc XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
    Arthur Kaser
    Division of Gastroenterology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Cell 134:743-56. 2008
    ..Hence, intestinal inflammation can originate solely from XBP1 abnormalities in IECs, thus linking cell-specific ER stress to the induction of organ-specific inflammation...
  36. doi request reprint Clinical significance of colonic intraepithelial lymphocytosis in a pediatric population
    Robert M Najarian
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Mod Pathol 22:13-20. 2009
    ..These findings are similar to those seen in adults, with the exception of autoimmune enteropathy...
  37. pmc Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Cell 16:208-19. 2009
    ..TRUC colitis-associated colorectal cancer resembles the human disease and provides ample opportunity to probe how inflammation drives colorectal cancer development and to test preventative and therapeutic strategies preclinically...
  38. pmc Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis
    Makoto Arita
    Center for Experimental Therapeutics and Reperfusion Injury, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 102:7671-6. 2005
    ..These findings show an endogenous mechanism that may underlie the beneficial actions of omega-3 EPA and provide targeted approaches for the treatment of intestinal inflammation...
  39. ncbi request reprint Fas (CD95/APO-1) and Fas ligand expression in normal pancreas and pancreatic tumors. Implications for immune privilege and immune escape
    Wolfram V Bernstorff
    Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Cancer 94:2552-60. 2002
    ..In the current study the authors have characterized the expression of Fas and FasL in the normal pancreas and in pancreatic neoplasia...
  40. ncbi request reprint Section II: pathology and pathologic staging of esophageal cancer
    Jonathan N Glickman
    Department of Pathology, Harvard Medical School, Brigham and Women s Hospital, Boston, MA 02115, USA
    Semin Thorac Cardiovasc Surg 15:167-79. 2003
    ..Early detection and treatment of these tumors is the most important factor in patient survival...
  41. ncbi request reprint MR imaging features of solid pseudopapillary tumor of the pancreas in adult and pediatric patients
    Vito Cantisani
    Section of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    AJR Am J Roentgenol 181:395-401. 2003
    ..This study was conducted to describe the MR imaging features of solid pseudopapillary tumor of the pancreas...
  42. pmc Matrix metalloproteinases in the urine and tissue of patients with juvenile polyps: potential biomarkers for the presence of polyps
    Michael A Manfredi
    Division of Gastroenterology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    J Pediatr Gastroenterol Nutr 48:405-11. 2009
    ..We hypothesized that the presence of these enzymes in urine may serve as clinical biomarkers of juvenile polyps...
  43. ncbi request reprint CT features of hepatic venoocclusive disease and hepatic graft-versus-host disease in patients after hematopoietic stem cell transplantation
    Sukru Mehmet Erturk
    Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Radiology Ste, c o One Brigham Circle, 1620 Tremont St, Boston, MA 02120, USA
    AJR Am J Roentgenol 186:1497-501. 2006
    ..We conducted this study to evaluate whether CT scans could be used to differentiate hepatic venoocclusive disease from hepatic graft-versus-host disease in patients treated with hematopoietic stem cell transplantation...
  44. ncbi request reprint Vaginal metastasis from uterine leiomyosarcoma. Magnetic resonance imaging features with pathological correlation
    Vito Cantisani
    Department of Radiology, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Comput Assist Tomogr 27:805-9. 2003
    ..The magnetic resonance imaging features are described and correlated with the pathological findings. To the best of our knowledge, this is the first case of vaginal metastasis from uterine leiomyosarcoma described in the literature...
  45. doi request reprint Variability of histopathological changes in childhood celiac disease
    Dascha C Weir
    Department of Pathology, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Gastroenterol 105:207-12. 2010
    ..Adult studies of celiac disease (CD) have shown that duodenal mucosal histopathological changes may be patchy, and the diagnostic utility of duodenal bulb biopsies is believed to be limited. Few related pediatric data exist...
  46. pmc Specific regulation of T helper cell 1-mediated murine colitis by CEACAM1
    Hideki Iijima
    Gastroenterology Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    J Exp Med 199:471-82. 2004
    ....
  47. ncbi request reprint CT features with pathologic correlation of acute gastrointestinal graft-versus-host disease after bone marrow transplantation in adults
    Babak N Kalantari
    Department of Radiology, Section of Abdominal Imaging and Intervention, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    AJR Am J Roentgenol 181:1621-5. 2003
    ..This study was conducted to describe the CT features of acute gastrointestinal graft-versus-host disease in adults and to correlate these findings with the pathologic grades of disease severity...
  48. doi request reprint High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss
    Matthew H Kulke
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    Genes Chromosomes Cancer 47:591-603. 2008
    ..This detailed study of an uncommon neoplasm provides a basis to investigate putative oncogenes and tumor suppressor genes in intestinal carcinoid tumors...
  49. ncbi request reprint Carcinoid tumors
    Chandrajit P Raut
    Harvard Medical School, Boston, Massachusetts, USA
    Curr Probl Surg 43:383-450. 2006
  50. pmc Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria
    Masaru Yoshida
    Department of Medicine, Brigham and Women s Hospital, and Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA
    J Clin Invest 116:2142-2151. 2006
    ....
  51. pmc Pathophysiological preconditions promoting mixed "black" pigment plus cholesterol gallstones in a DeltaF508 mouse model of cystic fibrosis
    Folke Freudenberg
    Department of Medicine, Harvard Medical School and Harvard Digestive Diseases Center Department of Medicine, Gastroenterology Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Am J Physiol Gastrointest Liver Physiol 299:G205-14. 2010
    ..This is an initial step toward unraveling the molecular basis of CF gallstone disease and constitutes a framework for investigating animal models of CF with more severe biliary disease, as well as the human disease...
  52. pmc A mutation in separase causes genome instability and increased susceptibility to epithelial cancer
    Jennifer L Shepard
    Children s Hospital, Boston, Massachusetts 02115, USA
    Genes Dev 21:55-9. 2007
    ..These data strongly support a conserved cross-species role for mitotic checkpoint genes in genetic stability and epithelial carcinogenesis...
  53. ncbi request reprint Smooth muscle remodeling of the gastroesophageal junction after endoluminal gastroplication
    Julia J Liu
    Division of Gastroenterology, Department of Pathology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Gastrointest Endosc 65:1023-7. 2007
    ..Despite suture loss, some patients have persistent symptomatic resolution...
  54. ncbi request reprint Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2
    GYORGY BAFFY
    Division of Endocrinology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Hepatology 35:753-61. 2002
    ..We conclude that increased expression of UCP2 in the livers of mice with genetically or diet-induced obesity exerts neither protective nor deleterious effects on the severity of fatty liver disease...
  55. ncbi request reprint Significance of squamous metaplasia-like change in the esophagus
    Robert D Odze
    Am J Surg Pathol 29:1259-61; author reply 1261-3. 2005
  56. ncbi request reprint Portal-venous gas unrelated to mesenteric ischemia
    Walter Wiesner
    Department of Radiology, Brigham and Women s Hospital, Harvard Medic Petersgraben 4, 4031 Basel, Switzerland wwiesner uhbs ch
    Eur Radiol 12:1432-7. 2002
    ..The knowledge about these conditions may help to avoid misinterpretation of CT findings, inappropriate clinical uncertainty and unnecessary surgery in certain cases...
  57. ncbi request reprint Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America
    Athos Bousvaros
    J Pediatr Gastroenterol Nutr 44:653-74. 2007
    ....
  58. pmc Mast cells are an essential hematopoietic component for polyp development
    Elias Gounaris
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Proc Natl Acad Sci U S A 104:19977-82. 2007
    ..Our data suggest that MC are an essential hematopoietic component for preneoplastic polyp development and are a novel target for therapeutic intervention...
  59. pmc Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon
    Kevin M Haigis
    Center for Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Nat Genet 40:600-8. 2008
    ..These studies demonstrate clear phenotypic differences between mutant Kras and Nras, and suggest that the oncogenic phenotype of mutant K-Ras might be mediated by noncanonical signaling through Ras effector pathways...