Research Topics
| Daniel GellerSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
Research Grants
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Detail Information
Publications
A quick and reliable screening measure for OCD in youth: reliability and validity of the obsessive compulsive scale of the Child Behavior ChecklistDaniel A Geller
Pediatric Psychopharmacology Clinic, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
Compr Psychiatry 47:234-40. 2006....
Perinatal factors affecting expression of obsessive compulsive disorder in children and adolescentsDaniel A Geller
Clinical and Research Program in Pediatric Psychopharmacology, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02318, USA
J Child Adolesc Psychopharmacol 18:373-9. 2008..To examine whether adverse perinatal experiences of children are associated with obsessive compulsive disorder (OCD) in youth...- Atomoxetine treatment for pediatric patients with attention-deficit/hyperactivity disorder with comorbid anxiety disorderDaniel Geller
Pediatric Psychopharmacology Research Program, Massachusetts General Hospital, 185 Alewife Brook Parkway, Cambridge, MA 02138, USA
J Am Acad Child Adolesc Psychiatry 46:1119-27. 2007.... - Examining the relationship between obsessive-compulsive disorder and attention-deficit/hyperactivity disorder in children and adolescents: a familial risk analysisDaniel Geller
Pediatric Psychopharmacology Program, Center for Human Genetics, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02113, USA
Biol Psychiatry 61:316-21. 2007..To use family study methodology to examine the relationship between obsessive-compulsive disorder (OCD) and attention-deficit/hyperactivity disorder (ADHD) in children and adolescents... - Paroxetine treatment in children and adolescents with obsessive-compulsive disorder: a randomized, multicenter, double-blind, placebo-controlled trialDaniel A Geller
Harvard Medical School, Boston, MA 02114, USA
J Am Acad Child Adolesc Psychiatry 43:1387-96. 2004..To assess the efficacy and safety of paroxetine for the treatment of pediatric obsessive-compulsive disorder... - Re-examining comorbidity of Obsessive Compulsive and Attention-Deficit Hyperactivity Disorder using an empirically derived taxonomyD A Geller
Pediatric OCD Clinic, Massachusetts General Hospital, WACC 725, 15 Parkman Street, Boston, MA 02114, USA
Eur Child Adolesc Psychiatry 13:83-91. 2004.... - Which SSRI? A meta-analysis of pharmacotherapy trials in pediatric obsessive-compulsive disorderDaniel A Geller
Pediatric OCD Problem, WACC 725, Massachusetts General Hospital, 15 Parkman Street, Boston, MA 02114, USA
Am J Psychiatry 160:1919-28. 2003.... - Impact of comorbidity on treatment response to paroxetine in pediatric obsessive-compulsive disorder: is the use of exclusion criteria empirically supported in randomized clinical trials?Daniel A Geller
Obsessive Compulsive Disorder Program, Pediatric Psychopharmacology Research Program, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02114, USA
J Child Adolesc Psychopharmacol 13:S19-29. 2003..To examine the influence of psychiatric comorbidity on response and relapse rates in children and adolescents treated with paroxetine for obsessive-compulsive disorder (OCD)... - Further evidence for co-segregation between pediatric obsessive compulsive disorder and attention deficit hyperactivity disorder: a familial risk analysisDaniel Geller
Pediatric Psychopharmacology Program, Department of Psychiatry, Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Biol Psychiatry 61:1388-94. 2007..To examine the relationship between obsessive compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD) in children and adolescents using familial risk analysis... - A double-blind comparison of desipramine and placebo in children and adolescents with chronic tic disorder and comorbid attention-deficit/hyperactivity disorderThomas Spencer
Pediatric Psychopharmacology Unit, Psychiatry Service, Massachusetts General Hospital, Boston, MA 02114, USA
Arch Gen Psychiatry 59:649-56. 2002..CONCLUSIONS: Treatment with desipramine was well tolerated and was associated with robust clinically significant reductions in tic and ADHD symptoms in children and adolescents with chronic tic disorders and ADHD diagnoses... 
Impact of obsessive-compulsive disorder on the antimanic response to olanzapine therapy in youth with bipolar disorderGagan Joshi
Pediatric Psychopharmacology Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
Bipolar Disord 12:196-204. 2010..To compare antimanic response to olanzapine therapy in youth with bipolar disorder (BPD) based on the status of comorbidity with obsessive-compulsive disorder (OCD)...- Does ADHD moderate the manifestation of anxiety disorders in children?Paul Hammerness
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, Cambridge, MA 02138, USA
Eur Child Adolesc Psychiatry 19:107-12. 2010..ADHD had a limited impact on the manifestation of anxiety disorder in children suggesting that ADHD and anxiety disorders are independently expressed... - Clinical characteristics of comorbid obsessive-compulsive disorder and bipolar disorder in children and adolescentsGagan Joshi
Pediatric Psychopharmacology Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
Bipolar Disord 12:185-95. 2010.... - Principal components analysis of obsessive-compulsive disorder symptoms in children and adolescentsS Evelyn Stewart
Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts 02114, USA
Biol Psychiatry 61:285-91. 2007..The purpose of this study was to conduct an exploratory principal components analysis of obsessive-compulsive (OC) symptoms in children and adolescents with OCD to identify improved phenotypes for future studies... - Reexamining Tic persistence and Tic-associated impairment in Tourette's Disorder: findings from a naturalistic follow-up studyBarbara J Coffey
Joint Program in Pediatric Psychopharmacology of Massachusetts General Hospital and McLean Hospital, Boston, Massachusetts, USA
J Nerv Ment Dis 192:776-80. 2004..These results support the view that TD is a persistent disorder, but suggest a dissociation between tic persistence and tic-associated dysfunction... - Atomoxetine treatment of ADHD in children with comorbid Tourette syndromeThomas J Spencer
Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, MA 02114 2696, USA
J Atten Disord 11:470-81. 2008..This study examines changes in severity of tics and ADHD during atomoxetine treatment in ADHD patients with Tourette syndrome (TS)... - Case series: Sensory intolerance as a primary symptom of pediatric OCDEric P Hazen
Clinical Research Program in Pediatric Psychopharmacology, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
Ann Clin Psychiatry 20:199-203. 2008..Marked intolerance or intrusive re-experiencing of ordinary sensory stimuli that in turn drive functionally impairing compulsive behaviors are occasionally seen in young children with OCD... - Donepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case seriesRobert L Doyle
Department of Psychiatry, Harvard Medical School, USA
J Atten Disord 9:543-9. 2006..Because work in dementia documents improvement in executive function deficits with the acetylcholinesterase inhibitor donepezil, the authors reason that similar benefits could be obtained in PDD... - Effects of atomoxetine on growth in children with attention-deficit/hyperactivity disorder following up to five years of treatmentThomas J Spencer
Massachusetts General Hospital Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
J Child Adolesc Psychopharmacol 17:689-700. 2007..To examine the effects on growth of long-term pharmacological treatment for attention-deficit/hyperactivity disorder (ADHD), we present findings from an ongoing 5-year study of the efficacy and safety of treatment with atomoxetine... - A controlled family study of attention-deficit/hyperactivity disorder and Tourette's disorderS Evelyn Stewart
Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
J Am Acad Child Adolesc Psychiatry 45:1354-62. 2006..CONCLUSIONS: TD and ADHD are not alternate phenotypes of a single underlying genetic cause. There is an increased risk of comorbid ADHD and TD in affected families, possibly reflecting some overlapping neurobiology or pathophysiology... - Obsessive-compulsive and spectrum disorders in children and adolescentsDaniel A Geller
Pediatric Obsessive Compulsive Disorder Program, Division of Pediatric Psychopharmacology, Massachusetts General Hospital, YAW 6A, Fruit Street, Boston, MA 02114, USA
Psychiatr Clin North Am 29:353-70. 2006..Often cognitive antecedents to these behaviors are less well developed than in more typical OCD, and behavioral interventions are the mainstay of treatment but with more variable success... - Performance of clinician versus self-report measures to identify obsessive-compulsive disorder in children and adolescentsS Evelyn Stewart
Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, USA
J Child Adolesc Psychopharmacol 15:956-63. 2005..Because self-report measures have been used in epidemiological studies, youth OCD prevalence rates may be higher than previously reported... - Does comorbid attention-deficit/hyperactivity disorder impact the clinical expression of pediatric obsessive-compulsive disorder?Daniel A Geller
Obsessive Compulsive Disorder Clinical Research Program, Massachusetts General Hospital, Boston 02114, USA
CNS Spectr 8:259-64. 2003..In such affected youths, both disorders contribute to morbid dysfunction and require treatment. More work is needed to determine whether OCD plus ADHD represents a developmentally and etiologically distinct form of the OCD syndrome... - Four-factor structure of obsessive-compulsive disorder symptoms in children, adolescents, and adultsS Evelyn Stewart
Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
J Am Acad Child Adolesc Psychiatry 47:763-72. 2008..Identification of a category-based OCD symptom dimension structure that is validated for use across child, adolescent, and adult age groups is necessary to guide ongoing translational research... - Dissociation between MEG alpha modulation and performance accuracy on visual working memory task in obsessive compulsive disorderKristina T Ciesielski
MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
Hum Brain Mapp 28:1401-14. 2007.... - Treatment of pediatric obsessive-compulsive disorder: a reviewElizabeth Mancuso
Clinical and Research Program in Pediatric Psychopharmacology, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02138, USA
J Child Adolesc Psychopharmacol 20:299-308. 2010..The purpose of this article is to review assessment and treatment strategies to include current advances in research... - Selective serotonin reuptake inhibitors in pediatric psychopharmacology: a review of the evidencePaul G Hammerness
Department of Psychiatry, Pediatric Psychopharmacology Research Program, Harvard Medical School, Boston, MA, USA
J Pediatr 148:158-65. 2006 - Increased MEG activation in OCD reflects a compensatory mechanism specific to the phase of a visual working memory taskKristina T Ciesielski
MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA
Neuroimage 24:1180-91. 2005..The findings do not support the concept of a faulty working memory mechanism per se in OCD... - Attention-deficit/hyperactivity disorder in children and adolescents with obsessive-compulsive disorder: fact or artifact?Daniel A Geller
Obsessive Compulsive Disorder Clinic, McLean Hospital, Belmont, MA 02478, USA
J Am Acad Child Adolesc Psychiatry 41:52-8. 2002.... - The promise and challenge of obsessive-compulsive disorder researchDaniel A Geller
Biol Psychiatry 61:263-5. 2007
Research Grants
- JUVENILE ONSET OCD AS A MEANINGFUL DEVELOPMENT SUBTYPEDaniel Geller; Fiscal Year: 2003..The clinical, scientific, and public health relevance of confirming or refuting these hypotheses is discussed. ..
- Obsessive-compulsive disorder (OCD) Collaborative Genetics Association StudyDaniel A Geller; Fiscal Year: 2010..The results of these analyses will guide future molecular strategies to identify genes involved in the pathogenesis of OCD. The clinical and genotype data from the sample will be publicly available for OCD genetics research. ..