Research Topics
| Sonia FriedmanSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
Doctor message can alter patients' behavior and attitudes regarding inflammatory bowel disease and colon cancerSonia Friedman
Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Inflamm Bowel Dis 18:1531-9. 2012..This study explores patient attitudes and behavior regarding inflammatory bowel disease (IBD), colonoscopies, and colon cancer risk...
Intravenous cyclosporine in refractory pyoderma gangrenosum complicating inflammatory bowel diseaseS Friedman
Division of Gastroenterology, Mount Sinai Medical Center, New York, New York, USA
Inflamm Bowel Dis 7:1-7. 2001..Pyoderma gangrenosum complicates inflammatory bowel disease in 2-3% of patients and often fails to respond to antibiotics, steroids, surgical debridement or even colectomy...- Management of inflammatory bowel disease during pregnancy and nursingS Friedman
Gastroenterology Division, Harvard Medical School, Brigham and Women s Hopital, Boston, MA 02115, USA
Semin Gastrointest Dis 12:245-52. 2001..Pregnant IBD patients should be followed in a facility where diagnostic tests, such as sigmoidoscopy and ultrasound, and surgery can be performed if necessary... - Management of neoplastic polyps in inflammatory bowel diseaseSonia Friedman
Gastroenterology Division, Harvard Medical School, Brigham and Women s Hospital, ASBII, Boston, Massachusetts, U S A
Inflamm Bowel Dis 9:260-6. 2003..As long as there is no flat dysplasia or adenocarcinoma elsewhere in the colon, a colectomy is not required. However, this group of patients requires increased colonoscopic surveillance... - Screening and surveillance colonoscopy in chronic Crohn's colitis: results of a surveillance program spanning 25 yearsSonia Friedman
Division of Gastroenterology, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Clin Gastroenterol Hepatol 6:993-8; quiz 953-4. 2008..Our initial results through August 1998 showed a 22% chance of developing definite dysplasia or cancer by the fourth surveillance examination. We now update the results of all examinations since September 1998 until April 2005... - General principles of medical therapy of inflammatory bowel diseaseSonia Friedman
Gastroenterology Division ASBII, Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Gastroenterol Clin North Am 33:191-208, viii. 2004..Finally, it provides a summary of the current accepted medical therapies for ulcerative colitis adn Crohn's disease and recommendations for using these medications in clinical practice... - Cancer in Crohn's diseaseSonia Friedman
Department of Medicine, Harvard Medical School, Boston, MA 02115, USA
Gastroenterol Clin North Am 35:621-39. 2006..The study of cancers that are associated with CD is an evolving field that surely will change given that immunomodulators and biologics are being used with greater frequency... - 5-aminosalicylate therapy is associated with higher 6-thioguanine levels in adults and children with inflammatory bowel disease in remission on 6-mercaptopurine or azathioprineScott Hande
Brigham and Women s Hospital, Boston, Massachusetts, USA
Inflamm Bowel Dis 12:251-7. 2006..We tested the theory that coadministration of 5-ASA agents with AZA/6-MP results in higher 6-TGn levels in a large cohort of children and adults with CD or ulcerative colitis (UC)... - Factors that affect adherence to surveillance colonoscopy in patients with inflammatory bowel diseaseSonia Friedman
Division of Gastroenterology, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Inflamm Bowel Dis 19:534-9. 2013..Patients with extensive ulcerative colitis or Crohn's disease of the colon have an increased risk of colon cancer and require colonoscopic surveillance. This study explores factors that affect adherence to surveillance colonoscopy... - Differential regulation of peripheral leukocyte genes in patients with active Crohn's disease and Crohn's disease in remissionRobert Burakoff
Brigham and Women s Hospital, GI Division, Boston, MA 02115, USA
J Clin Gastroenterol 44:120-6. 2010..Specific gene expression patterns and molecular biomarkers associated with active Crohn's disease could serve as such markers, thereby providing a novel approach to disease activity monitoring... - Are patients with inflammatory bowel disease receiving optimal care?Sarathchandra I Reddy
Division of Gastroenterology, Crohn s and Colitis Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Am J Gastroenterol 100:1357-61. 2005..The purpose of this study was to determine whether patients referred for a second opinion were receiving therapy in accordance with practice guidelines... - Blood-based biomarkers can differentiate ulcerative colitis from Crohn's disease and noninflammatory diarrheaRobert Burakoff
Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Inflamm Bowel Dis 17:1719-25. 2011..A blood test with the ability to differentiate Crohn's disease (CD) from ulcerative colitis (UC) and noninflammatory diarrhea would be useful in the clinical management of these diseases... - Multidetector-row computed tomography enterographic assessment of the ileal-anal pouch: descriptive radiologic analysis with endoscopic and pathologic correlationMark C Liszewski
Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Comput Assist Tomogr 36:394-9. 2012..To describe the multidetector-row computed tomography enterographic (MD-CTE) features of the ileal-anal pouch after ileal pouch anal anastomosis (IPAA) surgery and correlate them with pouch endoscopy and histopathologic findings... - Low-dose 18F-FDG PET/CT enterography: improving on CT enterography assessment of patients with Crohn diseasePaul B Shyn
Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Nucl Med 51:1841-8. 2010..The purpose of this study was to evaluate the diagnostic efficacy of low-dose, combined (18)F-FDG PET/CT enterography (PET/CTE), compared with CT enterography (CTE) alone, in the assessment of patients with Crohn disease... - Effects of cancer treatment on inflammatory bowel disease remission and reactivationJordan E Axelrad
Massachusetts General Hospital Crohn s and Colitis Center, Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Clin Gastroenterol Hepatol 10:1021-7.e1. 2012..Little is known about the effects of cancer therapy for extraintestinal malignancy in patients with inflammatory bowel diseases (IBDs)... - MDCT assessment of ulcerative colitis: radiologic analysis with clinical, endoscopic, and pathologic correlationBijal Patel
Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Abdom Imaging 37:61-9. 2012..Evaluate the utility of multidetector-row computed tomography (MDCT) in assessing the severity of ulcerative colitis (UC) in comparison with clinical assessment, colonoscopy, and histopathology... - Pediatric patients with untreated ulcerative colitis may present initially with unusual morphologic findingsJonathan N Glickman
Department of Pathology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Am J Surg Pathol 28:190-7. 2004..Therefore, the objectives of this study were to determine the clinical and pathologic features of new-onset UC in children and to compare the initial presentation of UC in this group with a control group of adults... - Pregnancy and nursing in inflammatory bowel diseaseSonia Friedman
Department of Medicine, Harvard Medical School, and Gastroenterology Division, Brigham and Women's Hospital, Boston, MA, USA
Gastroenterol Clin North Am 31:265-73, xii. 2002..This article outlines fertility in IBD, the effect of IBD on pregnancy, the effect of pregnancy on IBD, and the medical therapy available... 
Granulomatous tracheo-bronchitis associated with Crohn's diseaseKai Xia
Division of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts, USA
MedGenMed 6:18. 2004..The patient improved with a 6-week oral, followed by an additional 4-week inhaled, corticosteroid treatment. Since then, he has been doing well without relapse of pulmonary symptoms for 2 years...- Medical therapy and birth outcomes in women with Crohn's disease: what should we tell our patients?Sonia Friedman
Am J Gastroenterol 102:1414-6. 2007..Only a prospective pregnancy registry of IBD patients can adequately differentiate the effects of disease activity and medication use on adverse pregnancy outcomes... - Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurineMiles P Sparrow
Section of Gastroenterology and Nutrition, University of Chicago Medical Center, Chicago, Illinois, USA
Clin Gastroenterol Hepatol 5:209-14. 2007..We describe the use of allopurinol in AZA/6-MP nonresponders to deliberately shunt metabolism of 6-MP toward 6-thioguanine (6-TGN) and improve clinical responses...