Eva Maria Frickel

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. doi Parasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes
    Eva Maria Frickel
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA
    J Infect Dis 198:1625-33. 2008
  2. pmc Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT
    Oktay Kirak
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Science 328:243-8. 2010
  3. pmc Transnuclear mice with pre-defined T cell receptor specificities against Toxoplasma gondii obtained via SCNT
    Oktay Kirak
    Whitehead Institute for Biomedical Research, USA
    J Vis Exp . 2010
  4. pmc Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication
    Wendy Niedelman
    Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Infect Immun 81:4341-9. 2013
  5. pmc Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it
    Sebastian Virreira Winter
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America
    PLoS ONE 6:e24434. 2011
  6. ncbi Apicomplexan UCHL3 retains dual specificity for ubiquitin and Nedd8 throughout evolution
    Eva Maria Frickel
    Whitehead Institute, 9 Cambridge Center, Cambridge, MA 02142, USA
    Cell Microbiol 9:1601-10. 2007
  7. pmc Immunoglobulin G signaling activates lysosome/phagosome docking
    Vishal Trivedi
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 103:18226-31. 2006

Collaborators

Detail Information

Publications7

  1. doi Parasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes
    Eva Maria Frickel
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA
    J Infect Dis 198:1625-33. 2008
    ..Interferon-gamma-producing CD8+ T cells provide essential protection against T. gondii infection, but the epitopes recognized have so far remained elusive...
  2. pmc Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT
    Oktay Kirak
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Science 328:243-8. 2010
    ..The relative ease and speed with which such transnuclear models can be obtained holds promise for the construction of other disease models...
  3. pmc Transnuclear mice with pre-defined T cell receptor specificities against Toxoplasma gondii obtained via SCNT
    Oktay Kirak
    Whitehead Institute for Biomedical Research, USA
    J Vis Exp . 2010
    ..The relative ease and speed with which such transnuclear models can be obtained holds promise for the construction of other disease models...
  4. pmc Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication
    Wendy Niedelman
    Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Infect Immun 81:4341-9. 2013
    ..This IFN-γ-induced cell death and early egress limits replication in HFFs and could promote clearance of the parasite by immune cells. ..
  5. pmc Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it
    Sebastian Virreira Winter
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America
    PLoS ONE 6:e24434. 2011
    ..Depending on the virulence of the strains involved, numerous GBPs are brought to the PV as part of a large, multimeric structure to combat T. gondii...
  6. ncbi Apicomplexan UCHL3 retains dual specificity for ubiquitin and Nedd8 throughout evolution
    Eva Maria Frickel
    Whitehead Institute, 9 Cambridge Center, Cambridge, MA 02142, USA
    Cell Microbiol 9:1601-10. 2007
    ..The characterization of these apicomplexan UCHL3s adds to our understanding of the ubiquitin and Nedd8 pathways in these parasites...
  7. pmc Immunoglobulin G signaling activates lysosome/phagosome docking
    Vishal Trivedi
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 103:18226-31. 2006
    ..We propose that this pathway contributes to the role of antibodies in the protection against microbial infections...