Stefanie H Freeman

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint TAR-DNA binding protein 43 in Pick disease
    Stefanie H Freeman
    Department of Pathology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    J Neuropathol Exp Neurol 67:62-7. 2008
  2. pmc Adult onset leukodystrophy with neuroaxonal spheroids: clinical, neuroimaging and neuropathologic observations
    Stefanie H Freeman
    C S Kubik Laboratory for Neuropathology, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Brain Pathol 19:39-47. 2009
  3. ncbi request reprint Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains
    Martin Ingelsson
    Harvard Medical School, Massachusetts General Hospital, 114 16th Street, Charlestown, MA 02129, USA
    Acta Neuropathol 114:471-9. 2007
  4. pmc Preservation of neuronal number despite age-related cortical brain atrophy in elderly subjects without Alzheimer disease
    Stefanie H Freeman
    C S Kubik Laboratory for Neuropathology, Department of Pathology, Alzheimer Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA
    J Neuropathol Exp Neurol 67:1205-12. 2008
  5. ncbi request reprint Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report
    Brian J Bacskai
    MassGeneral Institute for Neurodegenerative Diseases, Department of Neurology, Charlestown, MA 02129, USA
    Arch Neurol 64:431-4. 2007
  6. ncbi request reprint Plasma Abeta levels do not reflect brain Abeta levels
    Stefanie H Freeman
    C S Kubik Laboratory for Neuropathology, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02129, USA
    J Neuropathol Exp Neurol 66:264-71. 2007

Detail Information

Publications6

  1. ncbi request reprint TAR-DNA binding protein 43 in Pick disease
    Stefanie H Freeman
    Department of Pathology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    J Neuropathol Exp Neurol 67:62-7. 2008
    ....
  2. pmc Adult onset leukodystrophy with neuroaxonal spheroids: clinical, neuroimaging and neuropathologic observations
    Stefanie H Freeman
    C S Kubik Laboratory for Neuropathology, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Brain Pathol 19:39-47. 2009
    ..These observations lend further support to the notion that white matter disease alone can account for dementia...
  3. ncbi request reprint Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains
    Martin Ingelsson
    Harvard Medical School, Massachusetts General Hospital, 114 16th Street, Charlestown, MA 02129, USA
    Acta Neuropathol 114:471-9. 2007
    ..In conclusion, we demonstrated increased but largely variable 4R tau/3R tau mRNA ratios in FTLD and PSP cases, suggesting heterogeneous pathophysiological processes within these disorders...
  4. pmc Preservation of neuronal number despite age-related cortical brain atrophy in elderly subjects without Alzheimer disease
    Stefanie H Freeman
    C S Kubik Laboratory for Neuropathology, Department of Pathology, Alzheimer Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA
    J Neuropathol Exp Neurol 67:1205-12. 2008
    ..These data suggest that loss of neuronal and dendritic architecture, rather than loss of neurons, underlies neocortical volume loss with increasing age in the absence of Alzheimer disease...
  5. ncbi request reprint Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report
    Brian J Bacskai
    MassGeneral Institute for Neurodegenerative Diseases, Department of Neurology, Charlestown, MA 02129, USA
    Arch Neurol 64:431-4. 2007
    ..Imaging revealed marked region specific binding of PiB and abnormal fluorodeoxyglucose uptake. Intervention Autopsy was performed 3 months after the PiB scan...
  6. ncbi request reprint Plasma Abeta levels do not reflect brain Abeta levels
    Stefanie H Freeman
    C S Kubik Laboratory for Neuropathology, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02129, USA
    J Neuropathol Exp Neurol 66:264-71. 2007
    ..We conclude that plasma levels of Abeta40 and Abeta42 are not robust correlates of histologic or biochemically assessed amyloid burdens in brain, although the influence of the APOE genotype should be further explored...