Research Topics
| Marlene P FreemanSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
The comorbidity of bipolar and anxiety disorders: prevalence, psychobiology, and treatment issuesMarlene P Freeman
University of Cincinnati College of Medicine, Biological Psychiatry Program, Department of Psychiatry, P O Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
J Affect Disord 68:1-23. 2002..Although symptoms of anxiety as well as anxiety disorders commonly occur in patients with bipolar disorder, the pathophysiologic, theoretical, and clinical significance of their co-occurrence has not been well studied...- Managing depression during pregnancyMarlene P Freeman
Center for Women s Mental Health, Massachusetts General Hospital, Boston, USA
J Clin Psychiatry 70:e25. 2009..Data on teratogenic risks of antidepressant use are inconsistent, but these risks should be taken into consideration. Overall, treatment should be individually tailored, and nonpharmacologic options may be appropriate... 
Supportive psychotherapy for perinatal depression: preliminary data for adherence and responseMarlene P Freeman
Perinatal and Reproductive Psychiatry Program, Massachusetts General Hospital, Boston, Massachusetts, USA
Depress Anxiety 27:39-45. 2010..We sought to determine patient factors associated with adherence and response to a manualized supportive psychotherapy designed for pregnant and postpartum women with major depressive disorder (MDD)...- Postpartum depression treatment and breastfeedingMarlene P Freeman
Center for Women s Mental Health, Massachusetts General Hospital, Boston, MA, USA
J Clin Psychiatry 70:e35. 2009..Therapeutic doses should be as low as possible, and infants (especially newborns) should be closely monitored for adverse events. Nonpharmacologic treatments should also be considered... - Complementary and Alternative Medicine (CAM): considerations for the treatment of major depressive disorderMarlene P Freeman
Center for Women s Mental Health, Massachusetts General Hospital, Simches Research Building, 185 Cambridge St, Boston, MA 02114, USA
J Clin Psychiatry 70:4-6. 2009..Patients should receive advice about all available treatment options, including risks, benefits, and possible drug interactions, as well as full evaluations and regular monitoring... - Pharmacokinetics of sertraline across pregnancy and postpartumMarlene P Freeman
Department of Psychiatry, Women s Mental Health Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
J Clin Psychopharmacol 28:646-53. 2008..Despite nonsignificant mean pharmacokinetic changes, the range of pharmacokinetic changes across pregnancy warrants careful monitoring of depressive symptoms in women with MDD in late pregnancy and further study... 
Omega-3 fatty acids for major depressive disorder associated with the menopausal transition: a preliminary open trialMarlene P Freeman
Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Menopause 18:279-84. 2011..We sought to obtain preliminary data regarding the efficacy of omega-3 fatty acids for major depressive disorder associated with the menopausal transition. Secondary outcomes were assessed for vasomotor symptoms (or hot flashes)...- Complementary and alternative medicine for major depressive disorder: a meta-analysis of patient characteristics, placebo-response rates, and treatment outcomes relative to standard antidepressantsMarlene P Freeman
Perinatal and Reproductive Psychiatry Program, Massachusetts General Hospital, 185 Cambridge St, 2nd Floor, Boston, MA 02114, USA
J Clin Psychiatry 71:682-8. 2010.... - Complementary and alternative medicine in major depressive disorder: the American Psychiatric Association Task Force reportMarlene P Freeman
Center for Women s Mental Health, Massachusetts General Hospital, Boston, MA 02114, USA
J Clin Psychiatry 71:669-81. 2010..To review selected complementary and alternative medicine (CAM) treatments for major depressive disorder (MDD)... - Omega-3 fatty acids in major depressive disorderMarlene P Freeman
Center for Women s Mental Health, Massachusetts General Hospital, Simches Research Building, 185 Cambridge St, Boston, MA 02114, USA
J Clin Psychiatry 70:7-11. 2009..For many individuals with major depressive disorder, augmentation with omega-3 fatty acids should be considered, as general health benefits are well established and adjunctive use is low risk... - Omega-3 fatty acids and supportive psychotherapy for perinatal depression: a randomized placebo-controlled studyMarlene P Freeman
Women s Mental Health Center, University of Texas Southwestern Medical Center, Dallas TX, USA
J Affect Disord 110:142-8. 2008..This study was designed to investigate the feasibility, safety, and efficacy of omega-3 fatty acids for perinatal depression in addition to supportive psychotherapy... - Complementary and alternative medicine for perinatal depressionMarlene P Freeman
Women s Mental Health Center, University of Texas Southwestern Medical Center, 6363 Forest Park, Suite 800, Dallas, TX 75235 9086, United States
J Affect Disord 112:1-10. 2009..Complementary and Alternative Medicine (CAM) treatments are widely used, accessible, and understudied for well-defined psychiatric indications. Women are more likely than men to both suffer from MDD and use CAM... - Omega-3 fatty acids: evidence basis for treatment and future research in psychiatryMarlene P Freeman
Women s Mental Health Program, Department of Psychiatry, University of Arizona College of Medicine, Tucson 85724 5002, USA
J Clin Psychiatry 67:1954-67. 2006..To determine if the available data support the use of omega-3 essential fatty acids (EFA) for clinical use in the prevention and/or treatment of psychiatric disorders... - Tolerability of omega-3 fatty acid supplements in perinatal womenMarlene P Freeman
Women s Mental Health Center, Department of Psychiatry, Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, 6363 Forest Park, Suite 800, Dallas, TX 75235 9086, USA
Prostaglandins Leukot Essent Fatty Acids 77:203-8. 2007..Benefits of omega-3 fatty acids in perinatal women are well documented, although fish intake has declined among perinatal women... - Selected integrative medicine treatments for depression: considerations for womenMarlene P Freeman
Women's Mental Health Program, Department of Psychiatry, University of Arizona College of Medicine, Tucson, USA
J Am Med Womens Assoc 59:216-24. 2004..An evidence-based integrative medicine approach brings together treatment options with proven efficacy and the public's desire for complementary and alternative medicine treatments... - Lithium: clinical considerations in internal medicineMarlene P Freeman
Women s Mental Health Program, Department of Psychiatry, University of Arizona College of Medicine, Tucson, AZ 85724 5002, USA
Am J Med 119:478-81. 2006..Important laboratory monitoring guidelines are included in this review. Lithium remains an important intervention for the treatment of mood disorders... - Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorderPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine and the Mental Health Care Line, Cincinnati, Ohio 45267 0559, USA
Biol Psychiatry 60:1020-2. 2006..The results of pilot trials suggest that omega-3 fatty acids may have efficacy in the treatment of mood symptoms in bipolar disorder... - Treatment of mood disorders during pregnancy and postpartumLee S Cohen
Perinatal and Reproductive Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA
Psychiatr Clin North Am 33:273-93. 2010..This article reviews the diagnosis and treatment guidelines of mood disorders during pregnancy and postpartum, with specific reference to the use of psychotropic medications during this critical time... - When she says "no" to medication: psychotherapy for antepartum depressionAnna R Brandon
Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Campus Box 7160, Chapel Hill, NC 27599 7160, USA
Curr Psychiatry Rep 13:459-66. 2011..This article summarizes findings to date regarding the use of psychotherapy for depression occurring during pregnancy and describes the adaptations made to tailor the treatment to the unique needs of women in the perinatal period... - Postpartum depression assessments at well-baby visits: screening feasibility, prevalence, and risk factorsMarlene P Freeman
Women s Mental Health Program, Department of Psychiatry, University of Arizona College of Medicine Tucson, Arizona 85724, USA
J Womens Health (Larchmt) 14:929-35. 2005..Postpartum depression (PPD) is a disorder with broad public health implications and consequences that impact almost every aspect of child development... - Sex differences in depressive response during monoamine depletions in remitted depressive subjectsFrancisco A Moreno
Department of Psychiatry, College of Medicine, University of Arizona Health Sciences Center, Tucson 85724, USA
J Clin Psychiatry 67:1618-23. 2006..The present study assessed the effects of sex on the mood response during acute monoamine depletion... - Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorderMukund Gnanadesikan
Department of Psychiatry, University of Arizona, Tuscon 85724, USA
Bipolar Disord 5:203-16. 2003..CONCLUSIONS: Other than lithium, there are few robust double-blind data to support the use of a variety of agents in the maintenance phase. However, uncontrolled data suggest that a number of agents merit further study... - The impact of reproductive events on the course of bipolar disorder in womenMarlene P Freeman
Department of Psychiatry, University of Arizona College of Medicine, Tucson 85724 5002, USA
J Clin Psychiatry 63:284-7. 2002..Little is known about the impact of female reproductive hormones on the course of bipolar disorder. This study was designed to assess the influence of reproductive events and hormonal therapies on the course of bipolar disorder in women... - Antenatal depression: a rationale for studying exerciseGeetha Shivakumar
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
Depress Anxiety 28:234-42. 2011..This review presents current knowledge on exercise during pregnancy, antidepressant effects of exercise, and the rationale for the specific study of exercise for antenatal depression... - Omega-3 Fatty acids in psychiatryDavid Mischoulon
Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, 1 Bowdoin Square, 6th Floor, Boston, MA 02114, USA Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA Electronic address
Psychiatr Clin North Am 36:15-23. 2013....