Research Topics
| Carlos Fernandez-del CastilloSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
Evolution of the Whipple procedure at the Massachusetts General HospitalCarlos Fernandez-del Castillo
Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Surgery 152:S56-63. 2012..The goal of this study was to investigate the evolution of pancreatoduodenectomy at the Massachusetts General Hospital (MGH)...- Implications of incidentally discovered, nonfunctioning pancreatic endocrine tumors: short-term and long-term patient outcomesAlex B Haynes
Department of Surgery, Massachusetts General Hospital, Wang Ambulatory Care Center 460, 15 Parkman St, Boston, MA 02114, USA
Arch Surg 146:534-8. 2011..To describe the characteristics and outcomes after resection of incidentally discovered, nonfunctioning pancreatic endocrine tumors (PETs)... 
Surgery of cystic neoplasmsCarlos Fernandez-del Castillo
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 15 Parkman Street, ACC 336, Boston, MA 02114, USA
Gastrointest Endosc Clin N Am 12:803-12, ix. 2002....- Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patientsCarlos Fernandez-del Castillo
Department of Surgery and Gastroenterology, Massachusetts General Hospital ACC 336, 15 Parkman Street, Boston, MA 02114, USA
Arch Surg 138:427-3; discussion 433-4. 2003..Widespread use of computed tomography and ultrasound has led to the identification of increasing numbers of patients with asymptomatic cystic lesions of the pancreas... - Mucinous cystic neoplasmsCarlos Fernandez-del Castillo
Pancreas Surgery Program, Massachusetts General Hospital, Harvard Medical School, 15 Parkman St, ACC 460, Boston, MA 02114, USA
J Gastrointest Surg 12:411-3. 2008..Surgery is the treatment of choice, and prognosis is excellent in the absence of invasive carcinoma... - Pancreatic neuroendocrine tumors with involved surgical margins: prognostic factors and the role of adjuvant radiotherapyNils D Arvold
Harvard Radiation Oncology Program, Harvard Medical School, Boston, MA, USA
Int J Radiat Oncol Biol Phys 83:e337-43. 2012..The role of adjuvant radiotherapy (RT) in these patients has not been characterized... - Improved contemporary surgical management of insulinomas: a 25-year experience at the Massachusetts General HospitalMehrdad Nikfarjam
Department of Surgery, Massachusetts General Hospital Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
Ann Surg 247:165-72. 2008..To determine changes in the management strategy of patients with insulinomas and identify critical factors in patient outcome... 
Novel xenograft and cell line derived from an invasive intraductal papillary mucinous neoplasm of the pancreas give new insights into molecular mechanismsStefan Fritz
Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Pancreas 39:308-14. 2010..Little is known about the genetic signature of IPMC. In this study, we describe a novel xenograft model and cell culture created to biologically and genetically characterize these tumors...- 851 resected cystic tumors of the pancreas: a 33-year experience at the Massachusetts General HospitalNakul P Valsangkar
General and GI Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Surgery 152:S4-12. 2012..The objective of this study was to identify trends in the diagnosis and treatment of cystic neoplasms of the pancreas using a retrospective review of patients from a surgical database at an academic referral center during a 33-year period... - Long-term outcomes of neoadjuvant chemotherapy before chemoradiation for locally advanced pancreatic cancerNils D Arvold
Harvard Radiation Oncology Program, Boston, Massachusetts, USA
Cancer 118:3026-35. 2012..Neoadjuvant chemotherapy before chemoradiation therapy (CRT) may improve outcomes for patients with locally advanced pancreatic cancer, but optimal management remains controversial, and prior reports have limited follow-up... - Phase I study of preoperative short-course chemoradiation with proton beam therapy and capecitabine for resectable pancreatic ductal adenocarcinoma of the headTheodore S Hong
Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Int J Radiat Oncol Biol Phys 79:151-7. 2011..To evaluate the safety of 1 week of chemoradiation with proton beam therapy and capecitabine followed by early surgery... - Does the mechanism of lymph node invasion affect survival in patients with pancreatic ductal adenocarcinoma?Ioannis T Konstantinidis
Department of Surgery, Massachusetts General Hospital, Boston, MA, USA
J Gastrointest Surg 14:261-7. 2010..Lymph node metastases are prognostically significant in pancreatic ductal adenocarcinoma. Little is known about the significance of direct lymph node invasion... - Current trends in pancreatic cystic neoplasmsCristina R Ferrone
Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Arch Surg 144:448-54. 2009..To define how patients with pancreatic cysts are being diagnosed and treated... - Endoscopic ultrasound guided fine needle aspiration biopsy of autoimmune pancreatitis: diagnostic criteria and pitfallsVikram Deshpande
Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
Am J Surg Pathol 29:1464-71. 2005.... - Implications and management of pancreatic fistulas following pancreaticoduodenectomy: the Massachusetts General Hospital experienceGregory Veillette
Department of Surgery, Massachusetts General Hospital, 15 Parkman St, Wang Ambulatory Care Center 460, Boston, MA 02114, USA
Arch Surg 143:476-81. 2008..To describe the management and impact of pancreatic fistulas in a high-volume center... - Outcomes and tolerability of chemoradiation therapy for pancreatic cancer patients aged 75 years or olderDavid T Miyamoto
Harvard Radiation Oncology Program, Harvard Medical School, Boston, MA, USA
Int J Radiat Oncol Biol Phys 77:1171-7. 2010..To review the outcomes and tolerability of full-dose chemoradiation in elderly patients aged 75 years or older with localized pancreatic cancer... - Quality of life in pancreatic cancer: analysis by stage and treatmentStefano Crippa
Wang Ambulatory Care Center 460, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 15 Parkman Street, Boston, MA 02114, USA
J Gastrointest Surg 12:783-93; discussion 793-4. 2008..One-year survival was 74%, 30%, and 16% for groups 1, 2, and 3 respectively (p=0.001). Pancreatic cancer prognosis is still dismal. In addition to long-term survival benefits, surgery impacts favorably quality of life... - Implications and cost of pancreatic leak following distal pancreatic resectionJ Ruben Rodriguez
Center for Clinical Effectiveness in Surgery, Harvard Medical School, Boston, USA
Arch Surg 141:361-5; discussion 366. 2006..We sought to provide an economic framework for potential interventions aimed at reducing its occurrence... - Pancreatic ductal adenocarcinoma: long-term survival does not equal cureCristina R Ferrone
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Surgery 152:S43-9. 2012..Our aim was to identify the prognostic factors for long-term survival after resection of pancreatic ductal adenocarcinoma related to patients, treatments, and tumor biology... - Incidental pancreatic cysts: do we really know what we are watching?Camilo Correa-Gallego
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Pancreatology 10:144-50. 2010..Most cystic neoplasms of the pancreas (CNPs) are incidentally discovered. Their management continues to be debated and preoperative diagnosis is often inaccurate... - Preoperative platelet count and survival prognosis in resected pancreatic ductal adenocarcinomaIsmael Dominguez
Department of Surgery, Massachusetts General Hospital, Wang Ambulatory Care Center 460, 15 Parkman Street, Boston, Massachusetts 02114, USA
World J Surg 32:1051-6. 2008..High platelet counts are associated with an adverse effect on survival in various neoplastic entities. The prognostic relevance of preoperative platelet count in pancreatic cancer has not been clarified... - Transgastric pancreaticogastric anastomosis: an alternative operative approach for middle pancreatectomyJennifer LaFemina
Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Arch Surg 145:476-81. 2010..To determine short-term outcomes following middle pancreatectomy with transgastric pancreaticogastric anastomosis... - [Malignancy prediction in endocrine pancreas neoplasias]Carlos Fernandez-del Castillo
Escuela de Medicina de Harvard, Massachusetts General Hospital, Boston 02114, USA
Rev Invest Clin 57:481-7. 2005 - Superior prognostic importance of perineural invasion vs. lymph node involvement after curative resection of duodenal adenocarcinomaStefano Cecchini
Department of Surgery, Massachusetts General Hospital, Boston, MA, USA
J Gastrointest Surg 16:113-20; discussion 120. 2012..Our aim is to examine prognostic factors in patients who underwent a curative resection of their duodenal adenocarcinoma... - Pancreatic fistula rates after 462 distal pancreatectomies: staplers do not decrease fistula ratesCristina R Ferrone
Department of General Surgery, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
J Gastrointest Surg 12:1691-7; discussion 1697-8. 2008..Pancreatic fistula is a major source of morbidity after distal pancreatectomy (DP). We reviewed 462 consecutive patients undergoing DP to determine if the method of stump closure impacted fistula rates... - Cystic pancreatic endocrine neoplasms: a distinct tumor type?Liliana Bordeianou
Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Am Coll Surg 206:1154-8. 2008..This study aims to describe the characteristics of CPENs in a large patient cohort... - Management of intraductal papillary mucinous neoplasmsStefano Crippa
Department of Surgery, Massachusetts General Hospital, Wang Ambulatory Care Center WACC 460, 15 Parkmann Street, Boston, MA 02114, USA
Curr Gastroenterol Rep 10:136-43. 2008..In this systematic review, we analyze the most recent publications related to IPMNs, with particular emphasis on problems related to managing this challenging disease... - Debridement and closed packing for sterile or infected necrotizing pancreatitis: insights into indications and outcomes in 167 patientsJ Ruben Rodriguez
Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Ann Surg 247:294-9. 2008..To examine the surgical indications and clinical outcomes of a large cohort of patients with necrotizing pancreatitis... - Pancreatic cysts 3 cm or smaller: how aggressive should treatment be?Dushyant V Sahani
Department of Radiology, Division of Abdominal Imaging, Massachusetts General Hospital, Boston, 02114, USA
Radiology 238:912-9. 2006.... - Gallbladder lesions identified on ultrasound. Lessons from the last 10 yearsIoannis T Konstantinidis
Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
J Gastrointest Surg 16:549-53. 2012..Possible mass lesions identified on ultrasound (US) of the gallbladder may prompt an aggressive surgical intervention due to the possibility of a malignant neoplasm... - Case records of the Massachusetts General Hospital. Case 20-2005. A 58-year-old man with locally advanced pancreatic cancerDavid P Ryan
Department of Hematology and Oncology, Massachusetts General Hospital, Boston, USA
N Engl J Med 352:2734-41. 2005 - Metastatic tumors in the pancreas in the modern eraIoannis T Konstantinidis
Department of Surgery, Massachusetts General Hospital, Boston, MA, USA
J Am Coll Surg 211:749-53. 2010..Our aim was to describe the clinicopathologic characteristics and patient outcomes in a modern series of patients who underwent metastasectomy, with an emphasis on RCC... - Prognosis of invasive intraductal papillary mucinous neoplasm depends on histological and precursor epithelial subtypesMari Mino-Kenudson
Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Gut 60:1712-20. 2011..The authors investigate the clinicopathological characteristics and the impact on survival of both the invasive component and its background IPMN... - Comparative performance of MDCT and MRI with MR cholangiopancreatography in characterizing small pancreatic cystsNisha I Sainani
Division of Abdominal Imaging and Interventional Radiology, Department of Radiology, Massachusetts General Hospital, 55 Fruit St, White 270, Boston, MA 02114 2696, USA
AJR Am J Roentgenol 193:722-31. 2009..The objective of our study was to compare MDCT with MRI-MR cholangiopancreatography (MRCP) in characterizing small pancreatic cysts (< or = 3 cm) and predicting aggressiveness... - Intraductal papillary mucinous neoplasm of pancreas: multi-detector row CT with 2D curved reformations--correlation with MRCPDushyant V Sahani
Department of Abdominal Imaging and Interventions, Massachusetts General Hospital, 55 Fruit St, White 270, Boston, MA 02114, USA
Radiology 238:560-9. 2006.... - Identification of a novel kindred with familial pancreatitis and pancreatic cancerJennifer LaFemina
Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Pancreatology 9:273-9. 2009..Multiple causative mutations have been identified. Here we describe a pancreatitis/pancreatic cancer (P/PC) family, which demonstrates pancreatitis and pancreatic cancer resulting from an uncharacterized mutation... - Global genomic analysis of intraductal papillary mucinous neoplasms of the pancreas reveals significant molecular differences compared to ductal adenocarcinomaStefan Fritz
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Ann Surg 249:440-7. 2009..To determine whether intraductal papillary mucinous neoplasms of the pancreas (IPMNs) have a different genetic background compared with ductal adenocarcinoma (PDAC)... - Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasiaOliver Strobel
Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
Gastroenterology 138:1166-77. 2010..A majority of PanIN are thought to arise from ducts. We identified a novel ductal compartment that is gathered in gland-like outpouches (pancreatic duct glands [PDG]) of major ducts and characterized its role in injury and metaplasia... - Cholesterol crystal embolization presenting as either solid or cystic pancreatic lesionIoannis T Konstantinidis
Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA
J Surg Oncol 102:706-8. 2010..CCE should be considered in patients with significant vascular disease, arrhythmias or vascular manipulation who present with a pancreatic mass... - Serous cystadenoma of the pancreas: tumor growth rates and recommendations for treatmentJennifer F Tseng
Departments of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Ann Surg 242:413-9; discussion 419-21. 2005..6 cm/y, it is significantly greater in large tumors. Whereas expectant management is reasonable in small asymptomatic tumors, we recommend resection for large serous cystadenomas regardless of the presence or absence of symptoms... - Cystic pancreatic lesions: a simple imaging-based classification system for guiding managementDushyant V Sahani
Division of Abdominal Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA
Radiographics 25:1471-84. 2005..Endoscopic ultrasonography-guided aspiration and biopsy is useful in cases that are indeterminate at cross-sectional imaging or that require observation... - Twenty-three years of the Warshaw operation for distal pancreatectomy with preservation of the spleenCristina R Ferrone
Department of Surgery, Massachusetts General Hospital, Boston, MA, USA
Ann Surg 253:1136-9. 2011..To describe our series of distal pancreatectomies with preservation of the spleen utilizing the Warshaw operation with a focus on possible long-term complications due to the development of gastric varices... - Plectin-1 is a biomarker of malignant pancreatic intraductal papillary mucinous neoplasmsDirk Bausch
Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114 2622, USA
J Gastrointest Surg 13:1948-54; discussion 1954. 2009..Improved detection of malignancy using novel biomarkers may therefore improve diagnostic accuracy. One such promising novel biomarker is Plectin-1 (Plec-1)... - Autoimmune pancreatitis: disease evolution, staging, response assessment, and CT features that predict response to corticosteroid therapyDushyant V Sahani
Department of Radiology, Massachusetts General Hospital Harvard Medical School, 55 Fruit St, White 270, Boston, MA 02114, USA
Radiology 250:118-29. 2009..To evaluate the evolution of morphologic features of autoimmune pancreatitis (AIP) at computed tomography (CT) and to identify imaging features that can predict AIP response to corticosteroid therapy (CST)... - Hedgehog is an early and late mediator of pancreatic cancer tumorigenesisSarah P Thayer
Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
Nature 425:851-6. 2003..These data suggest that this pathway may have an early and critical role in the genesis of this cancer, and that maintenance of hedgehog signalling is important for aberrant proliferation and tumorigenesis... - Dosimetric feasibility of hypofractionated proton radiotherapy for neoadjuvant pancreatic cancer treatmentKevin R Kozak
Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
Int J Radiat Oncol Biol Phys 68:1557-66. 2007..To evaluate tumor and normal tissue dosimetry of a 5 cobalt gray equivalent (CGE) x 5 fraction proton radiotherapy schedule, before initiating a clinical trial of neoadjuvant, short-course proton radiotherapy for pancreatic adenocarcinoma... - Cystic neoplasms of the pancreasWilliam R Brugge
Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, USA
N Engl J Med 351:1218-26. 2004 - Pancreatic cancer tumor size on CT scan versus pathologic specimen: implications for radiation treatment planningNils D Arvold
Harvard Radiation Oncology Program, Boston, MA, USA
Int J Radiat Oncol Biol Phys 80:1383-90. 2011..Dimensions of the primary tumor are increasingly relevant in an era of highly conformal radiotherapy... - Trends in presentation and survival for gallbladder cancer during a period of more than 4 decades: a single-institution experienceIoannis T Konstantinidis
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Arch Surg 144:441-7; discussion 447. 2009.... - Patients undergoing treatment for pancreatic adenocarcinoma can mount an effective immune response to vaccinationsJennifer F Tseng
Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Pancreatology 5:67-74. 2005..These data suggest that immunotherapy for pancreatic cancer may be feasible and merits further investigation... - Cytokeratin 19 is a powerful predictor of survival in pancreatic endocrine tumorsVikram Deshpande
Gastrointestinal Pathology Service, Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Am J Surg Pathol 28:1145-53. 2004..We hypothesize that a subgroup of PETs may share a common histogenesis with pancreatic adenocarcinomas... - Assessment of pancreatic tumor resectability with multidetector computed tomography: semiautomated console-generated images versus dedicated workstation-generated imagesAnand K Singh
Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Acad Radiol 15:1058-68. 2008.... - Management of pancreatic serous cystadenomasJennifer A Wargo
Harvard Medical School, Massachusetts General Hospital, White 506, 55 Fruit St, Boston, MA 02114, USA
Adv Surg 43:23-34. 2009..In addition, large (> 4 cm) serous cystadenomas should be resected in appropriate surgical candidates given their propensity for growth and developing symptoms... - Multidisciplinary approach to diagnosis and management of intraductal papillary mucinous neoplasms of the pancreasDushyant V Sahani
Department of Radiology, Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Clin Gastroenterol Hepatol 7:259-69. 2009..Furthermore, issues of multifocality and increased predisposition of the pancreas to ductal adenocarcinoma must be addressed at follow-up evaluation. A follow-up management algorithm also is proposed in this review... - Pylorus-preserving pancreaticoduodenectomy in the treatment of chronic pancreatitisRamon E Jimenez
Department of Surgery, Hartford Hospital, University of Connecticut School of Medicine, 80 Seymour Street, P. O. Box 5037, Hartford, Connecticut 06102, USA
World J Surg 27:1211-6. 2003..Our experience fails to show a distinct superiority of the PPPD over the Whipple operation... - Pancreatic cysts: preoperative diagnosis and clinical managementMartha Bishop Pitman
Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Cancer Cytopathol 118:1-13. 2010..High CEA level supports a mucinous cyst, as do KRAS mutation and good quality DNA levels. KRAS mutation and multiple LOH support malignancy... - Molecular characteristics and biological behaviours of the oncocytic and pancreatobiliary subtypes of intraductal papillary mucinous neoplasmsHong D Xiao
Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
J Pathol 224:508-16. 2011..However, the less frequent TP53 overexpression associated with the significantly lower rates of invasion and nodal disease in the oncocytic type correlates with better outcomes compared to the pancreatobiliary type... - Evolving patterns in the detection and outcomes of pancreatic neuroendocrine neoplasms: the Massachusetts General Hospital experience from 1977 to 2005Parsia A Vagefi
Department of Surgery, Massachusetts General Hospital Harvard Medical School, Boston, MA 02114, USA
Arch Surg 142:347-54. 2007..To assess changing patterns in the detection and outcomes of pancreatic neuroendocrine neoplasms (PNENs)... - Gastroenteropancreatic neuroendocrine tumors: role of imaging in diagnosis and managementDushyant V Sahani
Department of Radiology, Division of Abdominal Imaging and Interventional Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, White 270, Boston, MA 02114, USA
Radiology 266:38-61. 2013.... - Pancreatic surgery for adenocarcinomaAndrew L Warshaw
Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Curr Opin Gastroenterol 28:488-93. 2012..Nonetheless, recent observations have continued to provide incremental improvement in both our evidence for treatment regimens and the technology, resulting in better outcomes... - Clinical challenges and images in GI: image 3. Pancreatic acinar cell carcinoma with subcutaneous fat necrosisMarisa Cevasco
Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA
Gastroenterology 135:1054, 1433. 2008 - Branch-duct intraductal papillary mucinous neoplasms: observations in 145 patients who underwent resectionJ Ruben Rodriguez
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Gastroenterology 133:72-9; quiz 309-10. 2007..This study describes the combined experience of 2 tertiary centers with branch-duct IPMNs aiming to validate these recommendations... - Heterogeneity in signaling pathways of gastroenteropancreatic neuroendocrine tumors: a critical look at notch signaling pathwayHe Wang
Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
Mod Pathol 26:139-47. 2013..Further analysis of signaling pathways is critical for designing clinical trials in gastroenteropancreatic neuroendocrine tumors... - Ductulo-insular pancreatic endocrine neoplasms: clinicopathologic analysis of a unique subtype of pancreatic endocrine neoplasmsVikram Deshpande
Department of Pathology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Am J Surg Pathol 27:461-8. 2003..We conclude that DI-PETs are not uncommon and that they are biologically similar to other PETs. We also hypothesize that the ductal cells develop by transdifferentiation of the endocrine cells... - New metastatic lymph node ratio system reduces stage migration in patients undergoing D1 lymphadenectomy for gastric adenocarcinomaUgwuji N Maduekwe
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Ann Surg Oncol 17:1267-77. 2010..The ratio of metastatic to examined nodes (N ratio) is an effective prognostic tool, but has not been examined in Western patients undergoing primarily D1 lymphadenectomy... - Neutrophil metabolic activity but not neutrophil sequestration reflects the development of pancreatitis-associated lung injuryWerner Hartwig
Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Crit Care Med 30:2075-82. 2002..18FDG uptake, which is also accessible by positron emission tomography scanning, better quantitates the contribution of activated neutrophils to tissue injury than other measurements of neutrophil accumulation or sequestration... - Beta cell transdifferentiation does not contribute to preneoplastic/metaplastic ductal lesions of the pancreas by genetic lineage tracing in vivoOliver Strobel
Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Proc Natl Acad Sci U S A 104:4419-24. 2007.... - Direct medical costs of acute pancreatitis hospitalizations in the United StatesPeter J Fagenholz
Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Pancreas 35:302-7. 2007..To determine the direct medical costs of hospitalizations for acute pancreatitis in the United States and analyze the demographic characteristics of hospitalized patients... - Distal pancreatectomy with splenic preservation revisitedJ Ruben Rodriguez
Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Surgery 141:619-25. 2007..The purpose of this study was to examine the short-term implications of this operation, comparing it to the outcomes following distal pancreatectomy with splenectomy...