S V Farone

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi Further evidence for the diagnostic continuity between child and adolescent ADHD
    Stephen Faraone
    Pediatric Psychopharmacology Unit, Psychiatry Service, Massachusetts General Hospital, Boston, MA 02114, USA
    J Atten Disord 6:5-13. 2002
  2. ncbi Family study of girls with attention deficit hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA
    Am J Psychiatry 157:1077-83. 2000
  3. ncbi The nature and heritability of attention-deficit/hyperactivity disorder
    S V Faraone
    Clinical and Research Program in Pediatric Psychopharmacology, Child Psychiatry Service, Massachusetts General Hospital, USA
    Child Adolesc Psychiatr Clin N Am 10:299-316, viii-ix. 2001
  4. ncbi Meta-analysis of the association between the 7-repeat allele of the dopamine D(4) receptor gene and attention deficit hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit, Child Psychiatric Services, Massachusetts General Hospital, Boston 02114, USA
    Am J Psychiatry 158:1052-7. 2001
  5. ncbi Efficacy of Adderall and methylphenidate in attention deficit hyperactivity disorder: a reanalysis using drug-placebo and drug-drug response curve methodology
    S V Faraone
    Pediatric Psychopharmacology Unit, Child Psychiatry Services, Massachusetts General Hospital, Boston 02114, USA
    J Child Adolesc Psychopharmacol 11:171-80. 2001
  6. ncbi Attention deficit hyperactivity disorder with bipolar disorder in girls: further evidence for a familial subtype?
    S V Faraone
    Pediatric Psychopharmacology Unit, Psychiatry Service, ACC 725, Massachusetts General Hospital, Fruit Street, Boston, MA 02114, USA
    J Affect Disord 64:19-26. 2001
  7. ncbi Report from the second international meeting of the Attention Deficit Hyperactivity Disorder Molecular Genetics Network
    S V Farone
    Pediatric Psychopharmacology Unit, ACC 725, MGH, Fruit Street, Boston, MA 02114, USA
    Am J Med Genet 105:255-8. 2001
  8. ncbi Clinical correlates of ADHD in females: findings from a large group of girls ascertained from pediatric and psychiatric referral sources
    J Biederman
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    J Am Acad Child Adolesc Psychiatry 38:966-75. 1999
  9. ncbi Separating attention deficit hyperactivity disorder and learning disabilities in girls: a familial risk analysis
    A E Doyle
    Pediatric Psychopharmacology Unit, Child Psychiatry Service, Massachusetts General Hospital, Boston, 02114, USA
    Am J Psychiatry 158:1666-72. 2001
  10. ncbi Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions
    K L Lunetta
    Department of Biostatistical Science, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Am J Hum Genet 66:605-14. 2000

Detail Information

Publications67

  1. ncbi Further evidence for the diagnostic continuity between child and adolescent ADHD
    Stephen Faraone
    Pediatric Psychopharmacology Unit, Psychiatry Service, Massachusetts General Hospital, Boston, MA 02114, USA
    J Atten Disord 6:5-13. 2002
    ..To determine if there are differences in the clinical expression and correlates of ADHD between children and adolescents...
  2. ncbi Family study of girls with attention deficit hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA
    Am J Psychiatry 157:1077-83. 2000
    ..To help fill this gap in the literature, the authors assessed the familial transmission of ADHD in families ascertained through girls...
  3. ncbi The nature and heritability of attention-deficit/hyperactivity disorder
    S V Faraone
    Clinical and Research Program in Pediatric Psychopharmacology, Child Psychiatry Service, Massachusetts General Hospital, USA
    Child Adolesc Psychiatr Clin N Am 10:299-316, viii-ix. 2001
    ..Moreover, the effectiveness of stimulants, along with animal models of hyperactivity, point to catecholamine dysregulation as at least one source of ADHD brain dysfunction...
  4. ncbi Meta-analysis of the association between the 7-repeat allele of the dopamine D(4) receptor gene and attention deficit hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit, Child Psychiatric Services, Massachusetts General Hospital, Boston 02114, USA
    Am J Psychiatry 158:1052-7. 2001
    ..Although several studies have shown an association between ADHD and the 7-repeat allele of the dopamine D(4) receptor gene (DRD4), several studies have not. Thus, the status of the ADHD-DRD4 association is uncertain...
  5. ncbi Efficacy of Adderall and methylphenidate in attention deficit hyperactivity disorder: a reanalysis using drug-placebo and drug-drug response curve methodology
    S V Faraone
    Pediatric Psychopharmacology Unit, Child Psychiatry Services, Massachusetts General Hospital, Boston 02114, USA
    J Child Adolesc Psychopharmacol 11:171-80. 2001
    ..They further suggest that, compared with the Conners Teacher Rating Scale, the Clinical Global Impressions scale may be more sensitive to improvements at the "well end" of the spectrum of functioning...
  6. ncbi Attention deficit hyperactivity disorder with bipolar disorder in girls: further evidence for a familial subtype?
    S V Faraone
    Pediatric Psychopharmacology Unit, Psychiatry Service, ACC 725, Massachusetts General Hospital, Fruit Street, Boston, MA 02114, USA
    J Affect Disord 64:19-26. 2001
    ..To clarify the nosologic status of girls with attention deficit hyperactivity disorder (ADHD) who also satisfy diagnostic criteria for bipolar disorder (BPD)...
  7. ncbi Report from the second international meeting of the Attention Deficit Hyperactivity Disorder Molecular Genetics Network
    S V Farone
    Pediatric Psychopharmacology Unit, ACC 725, MGH, Fruit Street, Boston, MA 02114, USA
    Am J Med Genet 105:255-8. 2001
    ..Because the mode of inheritance of ADHD is likely to be complex, efforts to collaborate and cross-validate findings remain an important priority for researchers studying the molecular genetics of this disorder...
  8. ncbi Clinical correlates of ADHD in females: findings from a large group of girls ascertained from pediatric and psychiatric referral sources
    J Biederman
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    J Am Acad Child Adolesc Psychiatry 38:966-75. 1999
    ..The aim of this study was to examine clinical correlates of ADHD in females using comprehensive assessments in multiple domains of functioning...
  9. ncbi Separating attention deficit hyperactivity disorder and learning disabilities in girls: a familial risk analysis
    A E Doyle
    Pediatric Psychopharmacology Unit, Child Psychiatry Service, Massachusetts General Hospital, Boston, 02114, USA
    Am J Psychiatry 158:1666-72. 2001
    ....
  10. ncbi Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions
    K L Lunetta
    Department of Biostatistical Science, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Am J Hum Genet 66:605-14. 2000
    ..We apply our methods to a sample of families with attention-deficit/hyperactivity disorder and provide examples of how covariates and gene-environment and gene-gene interactions can be incorporated...
  11. ncbi Heterogeneity of childhood conduct disorder: further evidence of a subtype of conduct disorder linked to bipolar disorder
    J Wozniak
    Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    J Affect Disord 64:121-31. 2001
    ..Furthermore, they suggest that the comorbid condition of CD+BPD may be a distinct nosological entity. This suggests that clinicians treating CD or BPD children should consider the treatment implications of this comorbid condition...
  12. ncbi A controlled family study of children with DSM-IV bipolar-I disorder and psychiatric co-morbidity
    J Wozniak
    Clinical and Research Program in Pediatric Psychopharmacology and Adult ADHD at Massachusetts General Hospital, Boston, MA 02114, USA
    Psychol Med 40:1079-88. 2010
    ..To estimate the spectrum of familial risk for psychopathology in first-degree relatives of children with unabridged DSM-IV bipolar-I disorder (BP-I)...
  13. ncbi Social impairment in girls with ADHD: patterns, gender comparisons, and correlates
    R W Greene
    Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston 02114, USA
    J Am Acad Child Adolesc Psychiatry 40:704-10. 2001
    ....
  14. ncbi A family study of psychiatric comorbidity in girls and boys with attention-deficit/hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit, Child Psychiatry Service, Massachusetts General Hospital, Boston, Massachusetts 02114-3139, USA
    Biol Psychiatry 50:586-92. 2001
    ..Although this is consistent with prior work suggesting more similarities than differences in the nature of psychiatric comorbidity in ADHD boys and girls, we cannot make strong conclusions, owing to the possibility of cohort effects...
  15. ncbi Parsing pediatric bipolar disorder from its associated comorbidity with the disruptive behavior disorders
    T J Spencer
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, Massachusetts 02114-3139, USA
    Biol Psychiatry 49:1062-70. 2001
    ..What was previously considered refractory ADHD, oppositionality, aggression, and conduct disorder may respond after mood stabilization. We review these issues in this article...
  16. ncbi Current concepts on the neurobiology of Attention-Deficit/Hyperactivity Disorder
    J Biederman
    Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
    J Atten Disord 6:S7-16. 2002
    ....
  17. ncbi Impact of exposure to parental attention-deficit hyperactivity disorder on clinical features and dysfunction in the offspring
    J Biederman
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
    Psychol Med 32:817-27. 2002
    ..However, since exposure to parental ADHD was associated with a disruptive family environment, the identification and treatment of adults with ADHD may be an important component of the treatment plan of youth with ADHD...
  18. ncbi A controlled study of behavioral inhibition in children of parents with panic disorder and depression
    J F Rosenbaum
    Department of Psychiatry, Massachusetts General Hospital, Boston, 02114, USA
    Am J Psychiatry 157:2002-10. 2000
    ..Several lines of evidence suggest that behavioral inhibition is an index of anxiety proneness. The authors sought to replicate prior findings and examine the specificity of the association between behavioral inhibition and anxiety...
  19. ncbi Patterns of psychopathology and dysfunction in high-risk children of parents with panic disorder and major depression
    J Biederman
    Pediatric Psychopharmacology Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 158:49-57. 2001
    ....
  20. ncbi Assessing symptoms of attention deficit hyperactivity disorder in children and adults: which is more valid?
    S V Faraone
    Massachusetts General Hospital, Boston 02114, USA
    J Consult Clin Psychol 68:830-42. 2000
    ..They do not support the idea that parents of ADHD children are biased to report ADHD symptoms in themselves because of their exposure to an ADHD child...
  21. ncbi Towards further understanding of the co-morbidity between attention deficit hyperactivity disorder and bipolar disorder: a MRI study of brain volumes
    J Biederman
    Clinical and Research Program in Pediatric Psychopharmacology, Psychiatry Department, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychol Med 38:1045-56. 2008
    ....
  22. ncbi The long-term longitudinal course of oppositional defiant disorder and conduct disorder in ADHD boys: findings from a controlled 10-year prospective longitudinal follow-up study
    J Biederman
    Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychol Med 38:1027-36. 2008
    ....
  23. ncbi Investigation of variation in SNAP-25 and ADHD and relationship to co-morbid major depressive disorder
    J W Kim
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Med Genet B Neuropsychiatr Genet 144:781-90. 2007
    ..We further suggest that co-morbidity with MDD may enhance detection of the association between SNAP-25 and ADHD...
  24. ncbi Long-term stability of the Child Behavior Checklist in a clinical sample of youth with attention deficit hyperactivity disorder
    J Biederman
    Harvard Medical School, Massachusetts General Hospital and McLean Hospital, Boston, MA, USA
    J Clin Child Psychol 30:492-502. 2001
    ..These results support the informativeness of the CBCL as a useful measure of longitudinal course in clinical samples of youth with ADHD...
  25. ncbi Further evidence of association between behavioral inhibition and social anxiety in children
    J Biederman
    Department of Psychiatry, Massachusetts General Hospital, Boston, 02114, USA
    Am J Psychiatry 158:1673-9. 2001
    ..1 versus 50.8). CONCLUSIONS: This study adds to the growing literature suggesting an association between behavioral inhibition and social anxiety disorder and an inverse relationship between inhibition and disruptive behavior disorders...
  26. ncbi Meta-analysis identifies an association between the dopamine D2 receptor gene and schizophrenia
    S J Glatt
    Department of Psychiatry, Harvard Medical School at Massachusetts Mental Health Center, Boston, MA 02115, USA
    Mol Psychiatry 8:911-5. 2003
    ..Although more family-based studies are needed to confirm this relation, our results provide strong evidence that DRD2 influences susceptibility to schizophrenia...
  27. ncbi Pharmacotherapy of attention-deficit/hyperactivity disorder reduces risk for substance use disorder
    J Biederman
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Pediatrics 104:e20. 1999
    ..To assess the risk for substance use disorders (SUD) associated with previous exposure to psychotropic medication in a longitudinal study of boys with attention-deficit/hyperactivity disorder (ADHD)...
  28. ncbi Efficacy of Adderall for Attention-Deficit/Hyperactivity Disorder: a meta-analysis
    S V Faraone
    Harvard Medical School, the Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston, MA 02114, USA
    J Atten Disord 6:69-75. 2002
    ..Its efficacy was significant for clinician, parent, and teacher ratings, and for both fixed- and best-dose designs...
  29. ncbi Patterns of remission and symptom decline in conduct disorder: a four-year prospective study of an ADHD sample
    J Biederman
    Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, USA
    J Am Acad Child Adolesc Psychiatry 40:290-8. 2001
    ..To evaluate systematically the longitudinal course of conduct disorder (CD) in a sample of youths with attention-deficit hyperactivity disorder (ADHD) to determine the effects of a persistent course on outcome...
  30. ncbi Further evidence of association between two NET single-nucleotide polymorphisms with ADHD
    J W Kim
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Mol Psychiatry 13:624-30. 2008
    ..This is the first time that identical alleles of NET from different studies were implicated, and thus our report provides further evidence that the NET gene is involved in the etiology of ADHD...
  31. ncbi Evidence for an association of the dopamine D5 receptor gene on age at onset of attention deficit hyperactivity disorder
    J Lasky-Su
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Ann Hum Genet 71:648-59. 2007
    ..Although definitive conclusions await independent replication, these results suggest that a variant in DRD5 may affect age at onset for ADHD...
  32. ncbi Lack of association between parental alcohol or drug addiction and behavioral inhibition in children
    J Biederman
    Department of Psychiatry Unit of Clinical Psychopharmacology, Massachusetts General Hospital, Boston, 02114, USA
    Am J Psychiatry 158:1731-3. 2001
    ..CONCLUSIONS: These results are not consistent with the hypothesis linking behavioral inhibition to addictions...
  33. ncbi Association of neuropsychological vulnerability markers in relatives of schizophrenic patients
    R Toomey
    Harvard Institute of Psychiatric Epidemiology and Genetics, Boston, MA, USA
    Schizophr Res 31:89-98. 1998
    ..We discuss how the use of multiple risk indicators may help us better identify those relatives that carry the schizophrenia genotype...
  34. ncbi Diagnostic efficiency of neuropsychological test scores for discriminating boys with and without attention deficit-hyperactivity disorder
    A E Doyle
    Department of Psychiatry, Harvard Medical School at Massachusetts General Hospital, Boston 02114, USA
    J Consult Clin Psychol 68:477-88. 2000
    ..The prognostic implications of variable neuropsychological deficits in children with ADHD require further investigation...
  35. ncbi Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission definition and symptom type
    J Biederman
    Pediatric Psychopharmacology Unit, Psychiatry Service, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 157:816-8. 2000
    ..Symptom decline in attention deficit hyperactivity disorder (ADHD) was examined with different definitions of remission...
  36. ncbi The CBCL as a screen for psychiatric comorbidity in paediatric patients with ADHD
    J Biederman
    Pediatric Psychopharmacology Research Program, Massachusetts General Hospital, Yawkey Center for Patient Care YAW 6A 6900, Boston, MA 02114, USA
    Arch Dis Child 90:1010-5. 2005
    ..It was hypothesised that specific scales of the CBCL would help identify specific comorbidities within ADHD cases in the primary care setting...
  37. ncbi Systematic chart review of the pharmacologic treatment of comorbid attention deficit hyperactivity disorder in youth with bipolar disorder
    J Biederman
    Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston, USA
    J Child Adolesc Psychopharmacol 9:247-56. 1999
    ..Although TCAs can be helpful in the management of ADHD children with manic symptoms, these drugs should be used with caution since they can also have a destabilizing effect on manic symptoms...
  38. ncbi Genetic association analysis of behavioral inhibition using candidate loci from mouse models
    J W Smoller
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Med Genet 105:226-35. 2001
    ..This study illustrates the potential utility of using candidate genes derived from mouse models to dissect the genetic basis of BI, a possible intermediate phenotype for panic and phobic disorders...
  39. ncbi Stability of executive function deficits into young adult years: a prospective longitudinal follow-up study of grown up males with ADHD
    J Biederman
    Pediatric Psychopharmacology Program, Massachusetts General Hospital, Boston, MA 02114, USA
    Acta Psychiatr Scand 116:129-36. 2007
    ..Although individuals with attention deficit-hyperactivity disorder (ADHD) commonly exhibit deficits in executive functions that greatly increase the morbidity of the disorder, all available information on the subject is cross sectional...
  40. ncbi Neurocognitive impairment in unaffected siblings of youth with bipolar disorder
    A E Doyle
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Child Psychiatry Service, 55 Fruit Street, Boston, MA 02114, USA
    Psychol Med 39:1253-63. 2009
    ..The current study investigated whether these neurocognitive impairments index the familial risk underlying the diagnosis...
  41. ncbi Whole-genome association study of bipolar disorder
    P Sklar
    Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA
    Mol Psychiatry 13:558-69. 2008
    ..Given the heritability of BP disorder, the lack of agreement between studies emphasizes that susceptibility alleles are likely to be modest in effect size and require even larger samples for detection...
  42. ncbi Learning disabilities and executive dysfunction in boys with attention-deficit/hyperactivity disorder
    L J Seidman
    Department of Psychiatry, Harvard Medical School at Massachusetts General Hospital, Boston 02114, USA
    Neuropsychology 15:544-56. 2001
    ..These data indicate that comorbid LD, especially arithmetic disability, significantly increases the severity of executive function impairment in ADHD...
  43. ncbi Genes, environment and schizophrenia
    M T Tsuang
    Harvard Medical School, Department of Psychiatry at Massachusetts Mental Health Center, 74 Fenwood Road, Boston, MA 02115, USA
    Br J Psychiatry Suppl 40:s18-24. 2001
    ..Nevertheless, it remains clear that environmental factors both add to and interact with genetic factors to produce the disorder...
  44. ncbi Sleep disturbances associated with attention deficit hyperactivity disorder: the impact of psychiatric comorbidity and pharmacotherapy
    E Mick
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, USA
    J Child Adolesc Psychopharmacol 10:223-31. 2000
    ..To estimate the relative risk of sleep problems associated with attention deficit hyperactivity disorder (ADHD), its pharmacotherapy, and its comorbid psychopathology...
  45. ncbi Concurrent validation of schizotaxia: a pilot study
    W S Stone
    Department of Psychiatry at Massachusetts Mental Health Center, Harvard Medical School, 74 Fenwood Road, Boston, MA 02115, USA
    Biol Psychiatry 50:434-40. 2001
    ....
  46. ncbi Clinical correlates of obsessive compulsive disorder in children and adolescents referred to specialized and non-specialized clinical settings
    D Geller
    Joint Pediatric Psychopharmacology Program, Massachusetts General Hospital, Boston, USA
    Depress Anxiety 11:163-8. 2000
    ..It also suggests that pooling subjects from the two sources is justified. Nevertheless, because some group differences did emerge, researchers should acknowledge referral bias as a potential limitation of their work...
  47. ncbi Toward guidelines for pedigree selection in genetic studies of attention deficit hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston 02114, USA
    Genet Epidemiol 18:1-16. 2000
    ..This paper shows that these sub-phenotypes are useful for molecular genetic studies because (1) they have much higher empirical lambda values and (2) they affect a substantial minority of ADHD patients...
  48. ncbi Therapeutic dilemmas in the pharmacotherapy of bipolar depression in the young
    J Biederman
    Child Psychiatry Service, Massachusetts General Hospital, Boston, USA
    J Child Adolesc Psychopharmacol 10:185-92. 2000
    ..Because bipolar youth commonly come to clinical practice with depression, these results underscore the importance of assessing a lifetime history of bipolar disorder in making treatment decisions in depressed youth...
  49. ncbi The drug-placebo response curve: a new method for assessing drug effects in clinical trials
    S V Faraone
    The Pediatric Psychophamacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, and Harvard Medical School, Boston 02114, USA
    J Clin Psychopharmacol 20:673-9. 2000
    ..The drug-placebo response curve provides clinically relevant information about the effect of drugs on continuous outcomes in controlled clinical trials...
  50. ncbi Further evidence of an association between maternal smoking during pregnancy and attention deficit hyperactivity disorder: findings from a high-risk sample of siblings
    S Milberger
    Pediatric Pharmacology Unit, Massachusetts General Hospital, Boston 02114, USA
    J Clin Child Psychol 27:352-8. 1998
    ..Moreover, they highlight the importance of programs aimed at smoking prevention in nonsmoking women and smoking cessation in smoking women of child-bearing age...
  51. ncbi An open-label, dose-ranging study of atomoxetine in children with attention deficit hyperactivity disorder
    T Spencer
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA
    J Child Adolesc Psychopharmacol 11:251-65. 2001
    ..These results support additional controlled trials of atomoxetine in cases of pediatric ADHD...
  52. ncbi The genetics of schizophrenia
    M T Tsuang
    Harvard Medical School, Department of Psychiatry at the Massachusetts Mental Health Center, 74 Fenwood Road, Boston, MA 02115, USA
    Curr Psychiatry Rep 1:20-4. 1999
    ..The potential importance of schizotaxia, or similar concepts, for use in genetic studies, is discussed...
  53. ncbi Differential dopamine receptor D4 allele association with ADHD dependent of proband season of birth
    K J Brookes
    MRC Social Genetic Developmental and Psychiatry Centre, Institute of Psychiatry, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 147:94-9. 2008
    ..We conclude that the DRD4 7-repeat allele is associated with ADHD but there is no association or interaction with SOB for increased risk for ADHD. Our findings suggest that we can refute a possible effect of SOB for ADHD...
  54. ncbi The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes
    K Brookes
    MRC Social Genetic Developmental and Psychiatry Centre, Institute of Psychiatry, London, UK
    Mol Psychiatry 11:934-53. 2006
    ..Further studies will be needed to confirm or refute the observed associations and their generalisability to other samples...
  55. ncbi No association between two polymorphisms of the serotonin transporter gene and combined type attention deficit hyperactivity disorder
    X Xu
    MRC Social Genetic and Developmental Psychiatry, Institute of Psychiatry, London, UK
    Am J Med Genet B Neuropsychiatr Genet 147:1306-9. 2008
    ..No association was found between either of the two markers and ADHD in our large multisite study or with depression within the sample of ADHD cases...
  56. ncbi Adrenergic alpha2A receptor gene and response to methylphenidate in attention-deficit/hyperactivity disorder-predominantly inattentive type
    T L da Silva
    ADHD Outpatient Clinic, Child and Adolescent Psychiatric Division, Hospital de Clinicas de Porto Alegre, Federal University of Rio Grande do Sul, Rio Grande do Sul, Brazil
    J Neural Transm 115:341-5. 2008
    ..14; p = 0.016). We extended to ADHD-I previous findings suggesting the influence of the G allele at the ADRA2A -1291 C > G polymorphism on the improvement of inattentive symptoms with methylphenidate in children with all ADHD subtypes...
  57. ncbi Co-transmission of conduct problems with attention-deficit/hyperactivity disorder: familial evidence for a distinct disorder
    H Christiansen
    Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
    J Neural Transm 115:163-75. 2008
    ..The findings provide partial support for the ICD-10 distinction between hyperkinetic disorder (F90.0) and hyperkinetic conduct disorder (F90.1)...
  58. ncbi Differential family and peer environmental factors are related to severity and comorbidity in children with ADHD
    C J M Buschgens
    Department of Child and Adolescent Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Neural Transm 115:177-86. 2008
    ..These findings suggest that environmental influences that operate within ADHD families appear relevant to the severity of problem behaviors of ADHD children and their siblings...
  59. ncbi A high-density SNP linkage scan with 142 combined subtype ADHD sib pairs identifies linkage regions on chromosomes 9 and 16
    P Asherson
    Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Mol Psychiatry 13:514-21. 2008
    ..Meta-analysis or reanalysis of the raw data of all the available ADHD linkage scan data may help to clarify whether these represent true linked loci...
  60. ncbi Motor coordination problems in children and adolescents with ADHD rated by parents and teachers: effects of age and gender
    E Fliers
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Neural Transm 115:211-20. 2008
    ..Furthermore, we assessed whether the association between ADHD and motor coordination problems was comparable across ages and was similar for both genders...
  61. ncbi NIMH Genetics Initiative Millenium Schizophrenia Consortium: linkage analysis of African-American pedigrees
    C A Kaufmann
    College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Am J Med Genet 81:282-9. 1998
    ....
  62. ncbi Genetic counseling for psychiatric disorders
    D W Tsuang
    Department of Psychiatry and Behavioral Sciences, University of Washington, Mental Illness Research Education and Clinical Center, VA Puget Sound Health Care System, 1160 South Columbian Way, Seattle, WA 98108, USA. washington.edu
    Curr Psychiatry Rep 3:138-43. 2001
    ..Although medical and scientific advances may bring many gifts, we should approach this new knowledge with caution, as one of the gifts may be a Pandora's box...
  63. ncbi Genome scan of schizophrenia families in a large Veterans Affairs Cooperative Study sample: evidence for linkage to 18p11.32 and for racial heterogeneity on chromosomes 6 and 14
    S V Faraone
    Genetics Research Program and Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Am J Med Genet B Neuropsychiatr Genet 139:91-100. 2005
    ..11 at 33.2 cM) and 14 (LOD = 2.13 at 51.0). The linkage evidence differed between the AA and EA samples (chromosome 6 P-value = 0.007 and chromosome 14 P-value = 0.004)...
  64. ncbi Relapse of depression during pregnancy following antidepressant discontinuation: a preliminary prospective study
    L S Cohen
    Perinatal and Reproductive Psychiatry Clinical Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Arch Womens Ment Health 7:217-21. 2004
    ..Pregnancy has frequently been referred to as a time of emotional well-being for patients. However, systematic data about the risk for relapse of depression during pregnancy are sparse...
  65. ncbi Intelligence quotient and neuropsychological profiles in patients with schizophrenia and in normal volunteers
    W S Kremen
    Department of Psychiatry, University of California, Davis School of Medicine, 2516 Stockton Boulevard, Sacramento, CA 95817, USA
    Biol Psychiatry 50:453-62. 2001
    ..The results strengthen the argument that neurocognitive deficits are core deficits of schizophrenic illness...
  66. ncbi Modest evidence for linkage and possible confirmation of association between NOTCH4 and schizophrenia in a large Veterans Affairs Cooperative Study sample
    A D Skol
    Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA
    Am J Med Genet B Neuropsychiatr Genet 118:8-15. 2003
    ..The 8 and 13 repeat alleles were previously identified to be positively associated with schizophrenia by Wei and Hemmings [2000: Nat Genet 25:376-377] and Sklar et al. [2001: Nat Genet 28:126-128], respectively...
  67. ncbi More evidence supports the association of PPP3CC with schizophrenia
    Y L Liu
    Division of Mental Health and Substance Abuse Research, National Health Research Institutes, Taipei, Taiwan
    Mol Psychiatry 12:966-74. 2007
    ..05) and the executive functioning as tested by the Wisconsin Card Sorting Test (WCST, P<0.05). The results suggest that PPP3CC gene may be a true susceptibility gene for schizophrenia...