D R Elmaleh
Affiliation: Massachusetts General Hospital
- Anti-viral activity of human antithrombin IIIDavid R Elmaleh
Division of Nuclear Medicine and Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA
Int J Mol Med 16:191-200. 2005..Our data indicate that anti-viral inactive ATIII can be activated having promising anti-viral properties as complementary candidate for the treatment of HIV infection...
- Detection of inflamed atherosclerotic lesions with diadenosine-5',5'''-P1,P4-tetraphosphate (Ap4A) and positron-emission tomographyD R Elmaleh
Department of Radiology and Cardiology Division, Massachusetts General Hospital, Boston, MA 02114, USA
Proc Natl Acad Sci U S A 103:15992-6. 2006..The accumulation of [(18)F]AppCHFppA in macrophage-rich atherosclerotic plaques can be quantified noninvasively with PET. Hence, [(18)F]AppCHFppA holds promise for the noninvasive characterization of vascular inflammation...
- Rapid detection of Parkinson's disease by SPECT with altropane: a selective ligand for dopamine transportersA J Fischman
Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
Synapse 29:128-41. 1998..The high selectivity and rapid striatal accumulation of the ligand allows for accurate quantitation of DAT sites in less than 2 hr. The results further demonstrate that [123I]altropane is an effective marker for PD...
- Imaging amyloid deposition in Lewy body diseasesS N Gomperts
Massachusetts General Hospital, Boston, MA 02114, USA
Neurology 71:903-10. 2008..In addition to widespread distribution of Lewy bodies, both diseases have variable burdens of neuritic plaques and neurofibrillary tangles characteristic of Alzheimer disease (AD)...