Jeffrey L Ecker

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Postpartum diabetes screening in women with a history of gestational diabetes
    Karen V Smirnakis
    Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Obstet Gynecol 106:1297-303. 2005
  2. ncbi request reprint Predicting gestational diabetes: choosing the optimal early serum marker
    Karen V Smirnakis
    Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Am J Obstet Gynecol 196:410.e1-6; discussion 410.e6-7. 2007
  3. doi request reprint Elective cesarean delivery on maternal request
    Jeffrey Ecker
    Harvard Medical School, and Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA 02114, USA
    JAMA 309:1930-6. 2013
  4. ncbi request reprint An immodest proposal: banking embryonic stem cells for solid organ transplantation is problematic and premature
    Jeffrey L Ecker
    Partners HealthCare Systems, Boston, MA 02114, USA
    Am J Bioeth 7:48-50; discussion W4-6. 2007
  5. ncbi request reprint Cesarean delivery for suspected macrosomia: inefficient at best
    Jeffrey L Ecker
    Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, and Vincent Memorial Obstetric Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Obstet Gynecol 47:352-64. 2004
  6. doi request reprint Home birth: what are physicians' ethical obligations when patient choices may carry increased risk?
    Jeffrey Ecker
    Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Obstet Gynecol 117:1179-82. 2011
  7. doi request reprint Differing attitudes toward fetal care by pediatric and maternal-fetal medicine specialists
    Stephen D Brown
    Department of Radiology, Boston Children s Hospital, Boston, MA 02115, USA
    Pediatrics 130:e1534-40. 2012
  8. ncbi request reprint Circulating levels of the antiangiogenic marker sFLT-1 are increased in first versus second pregnancies
    Myles Wolf
    Renal Unit, Department of Medicine, Massachusetts General Hospital and the Renal Division, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston 02114, USA
    Am J Obstet Gynecol 193:16-22. 2005
  9. doi request reprint Epidural analgesia and risks of cesarean and operative vaginal deliveries in nulliparous and multiparous women
    Uyen Sa D T Nguyen
    Institute for Aging Research Hebrew SeniorLife, Boston, 02131, MA, USA
    Matern Child Health J 14:705-12. 2010
  10. ncbi request reprint First-trimester sex hormone binding globulin and subsequent gestational diabetes mellitus
    Ravi Thadhani
    Departments of Medicine and Obstetrics and Gynecology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Obstet Gynecol 189:171-6. 2003

Detail Information

Publications42

  1. ncbi request reprint Postpartum diabetes screening in women with a history of gestational diabetes
    Karen V Smirnakis
    Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Obstet Gynecol 106:1297-303. 2005
    ..We sought to examine postpartum glycemic testing in women diagnosed with GDM...
  2. ncbi request reprint Predicting gestational diabetes: choosing the optimal early serum marker
    Karen V Smirnakis
    Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Am J Obstet Gynecol 196:410.e1-6; discussion 410.e6-7. 2007
    ..To select an optimal early (<20 weeks) marker, we prospectively compared 3 serum markers examined simultaneously in a single cohort...
  3. doi request reprint Elective cesarean delivery on maternal request
    Jeffrey Ecker
    Harvard Medical School, and Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA 02114, USA
    JAMA 309:1930-6. 2013
    ..Some pregnant women prefer cesarean delivery and request it without maternal or fetal indication rather than proceeding with a plan for vaginal delivery...
  4. ncbi request reprint An immodest proposal: banking embryonic stem cells for solid organ transplantation is problematic and premature
    Jeffrey L Ecker
    Partners HealthCare Systems, Boston, MA 02114, USA
    Am J Bioeth 7:48-50; discussion W4-6. 2007
  5. ncbi request reprint Cesarean delivery for suspected macrosomia: inefficient at best
    Jeffrey L Ecker
    Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, and Vincent Memorial Obstetric Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Obstet Gynecol 47:352-64. 2004
  6. doi request reprint Home birth: what are physicians' ethical obligations when patient choices may carry increased risk?
    Jeffrey Ecker
    Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Obstet Gynecol 117:1179-82. 2011
    ....
  7. doi request reprint Differing attitudes toward fetal care by pediatric and maternal-fetal medicine specialists
    Stephen D Brown
    Department of Radiology, Boston Children s Hospital, Boston, MA 02115, USA
    Pediatrics 130:e1534-40. 2012
    ....
  8. ncbi request reprint Circulating levels of the antiangiogenic marker sFLT-1 are increased in first versus second pregnancies
    Myles Wolf
    Renal Unit, Department of Medicine, Massachusetts General Hospital and the Renal Division, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston 02114, USA
    Am J Obstet Gynecol 193:16-22. 2005
    ..Additional studies are needed to verify these findings and to further examine ethnic differences in angiogenesis factors and their potential impact on the incidence of preeclampsia...
  9. doi request reprint Epidural analgesia and risks of cesarean and operative vaginal deliveries in nulliparous and multiparous women
    Uyen Sa D T Nguyen
    Institute for Aging Research Hebrew SeniorLife, Boston, 02131, MA, USA
    Matern Child Health J 14:705-12. 2010
    ..6, 5.3) in multiparous women. Epidural anesthesia increases the risk for operative vaginal deliveries in both nulliparous and multiparous women, and increases risk for cesarean deliveries in nulliparous more so than in multiparous women...
  10. ncbi request reprint First-trimester sex hormone binding globulin and subsequent gestational diabetes mellitus
    Ravi Thadhani
    Departments of Medicine and Obstetrics and Gynecology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Obstet Gynecol 189:171-6. 2003
    ..We sought to examine the association between early pregnancy levels of sex hormone binding globulin and subsequent gestational diabetes mellitus, an association that has not been studied previously...
  11. ncbi request reprint Early pregnancy insulin resistance and subsequent gestational diabetes mellitus
    Karen V Smirnakis
    GRB 1003, Renal Unit, Department of Medicine, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Diabetes Care 28:1207-8. 2005
  12. doi request reprint Does professional orientation predict ethical sensitivities? Attitudes of paediatric and obstetric specialists toward fetuses, pregnant women and pregnancy termination
    Stephen D Brown
    Department of Radiology, Boston Children s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Med Ethics 40:117-22. 2014
    ....
  13. ncbi request reprint Case records of the Massachusetts General Hospital. Case 38-2005. A 29-year-old pregnant woman with the nephrotic syndrome and hypertension
    Winfred W Williams
    Division of Nephrology, Department of Medicine, Massachusetts General Hospital, USA
    N Engl J Med 353:2590-600. 2005
  14. doi request reprint Risk for developing gestational diabetes in women with twin pregnancies
    Jose A Rauh-Hain
    Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Matern Fetal Neonatal Med 22:293-9. 2009
    ..To examine the risk of developing gestational diabetes mellitus (GDM) in women with twin compared with singleton pregnancies...
  15. pmc General health, health conditions, and current pregnancy among U.S. women with and without chronic physical disabilities
    Lisa I Iezzoni
    Mongan Institute for Health Policy, Massachusetts General Hospital, USA Department of Medicine, Harvard Medical School, USA Electronic address
    Disabil Health J 7:181-8. 2014
    ..Although increasing numbers of reproductive-age U.S. women with chronic physical disabilities (CPD) are becoming pregnant, little is known about their general health or comorbid health conditions...
  16. ncbi request reprint Methylergonovine maleate and the risk of myocardial ischemia and infarction
    Brian T Bateman
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA Harvard Medical School, Boston, MA
    Am J Obstet Gynecol 209:459.e1-459.e13. 2013
    ....
  17. ncbi request reprint Preeclampsia and future cardiovascular disease: potential role of altered angiogenesis and insulin resistance
    Myles Wolf
    Renal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 89:6239-43. 2004
    ..Women with a history of preeclampsia demonstrate altered expression of angiogenesis-related proteins and increased HOMA(IR) more than 1 yr postpartum. These factors may contribute to their risk of future CVD...
  18. doi request reprint Altered arterial compliance in hypertensive pregnant women is associated with preeclampsia
    Andrea Coppadoro
    Departments of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School at Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Anesth Analg 116:1050-6. 2013
    ..In this study, we assessed arterial compliance in women affected by hypertensive disorders of pregnancy. We hypothesized that arterial compliance is reduced in women affected by preeclampsia...
  19. doi request reprint Fetal macrosomia and shoulder dystocia in women with gestational diabetes: risks amenable to treatment?
    Brett C Young
    Massachusetts General Hospital, Division of Maternal Fetal Medicine, 55 Fruit Street, Founders 4th Floor, Boston, MA 02114, USA
    Curr Diab Rep 13:12-8. 2013
    ....
  20. doi request reprint Prenatally diagnosed fetal conditions in the age of fetal care: does who counsels matter?
    Stephen D Brown
    Department of Radiology, Children s Hospital Boston, Boston, MA 02115, USA
    Am J Obstet Gynecol 206:409.e1-11. 2012
    ..We sought to characterize practices and attitudes of maternal-fetal medicine (MFM) and fetal care pediatric (FCP) specialists regarding fetal abnormalities...
  21. ncbi request reprint Differential risk of hypertensive disorders of pregnancy among Hispanic women
    Myles Wolf
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Soc Nephrol 15:1330-8. 2004
    ..The initial presentation of hypertension during pregnancy in Hispanic women most likely represents early preeclampsia...
  22. doi request reprint Second trimester insulin resistance, early pregnancy body mass index and gestational weight gain
    Alison M Stuebe
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA, USA
    Matern Child Health J 14:254-60. 2010
    ..Because prior work suggests an association between high insulin concentrations in early pregnancy and excess gestational weight gain, we examined such associations in a prospective cohort...
  23. ncbi request reprint Inflammation and glucose intolerance: a prospective study of gestational diabetes mellitus
    Myles Wolf
    Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Diabetes Care 27:21-7. 2004
    ..Although gestational diabetes mellitus (GDM) and type 2 diabetes share certain pathophysiological mechanisms, few studies have examined inflammation and risk of GDM...
  24. ncbi request reprint First-trimester C-reactive protein and subsequent gestational diabetes
    Myles Wolf
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Diabetes Care 26:819-24. 2003
    ..We tested the hypothesis that increased inflammation, measured early in pregnancy, is associated with the subsequent development of gestational diabetes mellitus (GDM), a precursor of type 2 diabetes...
  25. ncbi request reprint Insulin resistance but not inflammation is associated with gestational hypertension
    Myles Wolf
    Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass 02114, USA
    Hypertension 40:886-91. 2002
    ..Furthermore, important mechanistic differences exist in the pathogenesis of gestational hypertension comparing nulliparous and multiparous women...
  26. ncbi request reprint First trimester insulin resistance and subsequent preeclampsia: a prospective study
    Myles Wolf
    Renal Unit, Departments of Medicine and Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 87:1563-8. 2002
    ..First trimester SHBG levels may be a useful biomarker for preeclampsia, especially among lean women who otherwise would be perceived to be at low risk...
  27. ncbi request reprint Randomized comparison of chromic versus fast-absorbing polyglactin 910 for postpartum perineal repair
    James A Greenberg
    Department of Obstetrics, Brigham and Women s Hospital, Boston, Massachusetts
    Obstet Gynecol 103:1308-13. 2004
    ..We conducted a randomized trial to evaluate the healing characteristics of chromic versus fast-absorbing polyglactin 910...
  28. ncbi request reprint Do differences in the American Academy of Pediatrics and the American College of Obstetricians and Gynecologists positions on the ethics of maternal-fetal interventions reflect subtly divergent professional sensitivities to pregnant women and fetuses?
    Stephen D Brown
    Department of Radiology, Children s Hospital, Boston, MA 02115, USA
    Pediatrics 117:1382-7. 2006
    ..We urge leaders from both disciplines to meet and seek consensus so that a common approach and language can guide treatment of the patients whom we share...
  29. ncbi request reprint Cesarean delivery and the risk-benefit calculus
    Jeffrey L Ecker
    Harvard Medical School, Boston, USA
    N Engl J Med 356:885-8. 2007
  30. ncbi request reprint Transfers among women intending a birth center delivery in the San Diego birth center study
    Uyen Sa D T Nguyen
    Institute forAging Research, Hebrew SeniorLife, 1200 Centre St, Boston, MA 02131 1097, USA
    J Midwifery Womens Health 54:104-10. 2009
    ..Understanding predictors of transfer may assist practitioners, patients, and policy makers in considering the appropriateness of individuals for birth center delivery or to target further education to reduce nonmedical transfers...
  31. pmc Prevalence of current pregnancy among US women with and without chronic physical disabilities
    Lisa I Iezzoni
    Mongan Institute for Health Policy, Massachusetts General Hospital, Boston, MA 02114, USA
    Med Care 51:555-62. 2013
    ..However, little is known about their reproductive experiences. Historically, women with physical disabilities have confronted stigmatized attitudes about becoming pregnant...
  32. pmc Patterns of outpatient antihypertensive medication use during pregnancy in a Medicaid population
    Brian T Bateman
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Hypertension 60:913-20. 2012
    ..1%) in the third trimester. Antihypertensive use during pregnancy is relatively common and increasing. The wide range of agents used during pregnancy includes medications considered contraindicated during pregnancy...
  33. doi request reprint Dendritic cells in the circulation of women with preeclampsia demonstrate a pro-inflammatory bias secondary to dysregulation of TLR receptors
    Britta Panda
    Massachusetts General Hospital, Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Boston, MA 02114, USA
    J Reprod Immunol 94:210-5. 2012
    ..These data demonstrate a dysregulated pattern of TLR expression and cytokine production in DCs from PE patients that may limit further activation by TLR engagement...
  34. doi request reprint Expression of progesterone receptor membrane component 1 and its partner serpine 1 mRNA binding protein in uterine and placental tissues of the mouse and human
    Ling Zhang
    Vincent Center for Reproductive Biology, Harvard Medical School, Boston, MA 02114, USA
    Mol Cell Endocrinol 287:81-9. 2008
    ..These studies provide a platform from which to build a clearer understanding of P(4) actions in the female reproductive tract and placental tissues that are mediated by non-classical mechanisms...
  35. ncbi request reprint Once a pregnancy, always a cesarean? Rationale and feasibility of a randomized controlled trial
    Jeffrey L Ecker
    Vincent Memorial Obstetric Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Am J Obstet Gynecol 190:314-8. 2004
    ..To weigh the relative merits of elective primary cesarean delivery and a trial of labor, a randomized controlled trial is needed. Such a trial would be both ethical and feasible...
  36. ncbi request reprint Insulin resistance and alterations in angiogenesis: additive insults that may lead to preeclampsia
    Ravi Thadhani
    Renal Unit, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA
    Hypertension 43:988-92. 2004
    ..1, 95% CI 1.7 to 134.9; high PlGF and low SHBG, OR 4.1, 95% CI 0.45 to 38.2; low PlGF and high SHBG, OR 8.7, 95% CI 1.2 to 60.3. Altered angiogenesis and insulin resistance are additive insults that lead to preeclampsia...
  37. doi request reprint Is an episiotomy necessary with a shoulder dystocia?
    Amy E Paris
    Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA
    Am J Obstet Gynecol 205:217.e1-3. 2011
    ..The objective of the study was to determine whether a decrease in the use of episiotomy was associated with a change in the frequency of brachial plexus injury...
  38. ncbi request reprint Placental villitis of unclear etiology during ovum donor in vitro fertilization pregnancy
    Aaron K Styer
    Department of Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Boston, MA, USA
    Am J Obstet Gynecol 189:1184-6. 2003
    ....
  39. doi request reprint Gestational diabetes--setting limits, exploring treatments
    Jeffrey L Ecker
    N Engl J Med 358:2061-3. 2008
  40. ncbi request reprint US evaluation of fetal growth: prediction of neonatal outcomes
    Rebecca Smith-Bindman
    Department of Radiology, University of California, San Francisco, CA 94115, USA
    Radiology 223:153-61. 2002
    ..To determine whether fetal growth measured at serial ultrasonographic (US) examinations can predict neonatal morbidity, independent of whether gestational age is known...
  41. doi request reprint Minors as living solid-organ donors
    Lainie Friedman Ross
    Pediatrics 122:454-61. 2008
    ..The American Academy of Pediatrics holds that minors can morally serve as living organ donors but only in exceptional circumstances when specific criteria are fulfilled...
  42. ncbi request reprint Research profile. Gestational diabetes. Are prediction and prevention possible?
    Terri Kordella
    Diabetes Forecast 57:109-11. 2004