Research Topics
| W DzikSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Reversal of drug-induced anticoagulation: old solutions and new problemsWalter Sunny Dzik
Blood Transfusion Service, J 224 Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Transfusion 52:45S-55S. 2012..This review is presented to assist transfusion medicine specialists, hematologists, and other clinicians who prescribe blood components for reversal of drug-induced anticoagulation...
Clinical review: Canadian National Advisory Committee on Blood and Blood Products--Massive transfusion consensus conference 2011: report of the panelWalter H Dzik
Blood Transfusion Service, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Crit Care 15:242. 2011..The present report is intended to provide guidance to practitioners, hospitals, and policy-makers...
Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in UgandaChristine M Cserti-Gazdewich
Department of Laboratory Medicine and Pathobiology, University Health Network University of Toronto, Canada
Malar J 9:233. 2010..falciparum infection exhibiting a spectrum of clinical severity...
The impact of the National Blood FoundationWalter H Dzik
Blood Transfusion Service, Massachusetts General Hospital, Boston, Massachusetts, 02114, USA
Transfusion 45:41S-3S. 2005
The NHLBI Clinical Trials Network in transfusion medicine and hemostasis: an overviewWalter H Dzik
Blood Transfusion Service, Boston, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA
J Clin Apher 21:57-9. 2006..Examples of clinical trials currently in the network "pipeline" are briefly summarized as an overview to more detailed presentations given elsewhere in this symposium...
Off-label reports of new biologics: exciting new therapy or dubious research? Examples from recombinant activated factor VIIWalter H Dzik
Blood Tranfusion Service, Massachusetts General Hospital, Boston, 02114, USA
J Intensive Care Med 21:54-9. 2006
New technology for transfusion safetyWalter H Dzik
Massachusetts General Hospital, Boston, MA 02114, USA
Br J Haematol 136:181-90. 2007....
How I do it: platelet support for refractory patientsSunny Dzik
Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Transfusion 47:374-8. 2007
The James Blundell Award Lecture 2006: transfusion and the treatment of haemorrhage: past, present and futureW H Dzik
Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusettes, USA
Transfus Med 17:367-74. 2007..Ultimately, the application of widescale genomics testing will refresh our understanding of human physiology and will reassert the importance of the individual in patient care...
Errors in patient specimen collection: application of statistical process controlWalter Sunny Dzik
Blood Transfusion Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Transfusion 48:2143-51. 2008..Statistical process control (SPC) is a recognized method to monitor the performance of a critical process. An easy-to-use SPC method was tested to determine its feasibility as a tool for monitoring quality in transfusion medicine...
Fresh blood for everyone? Balancing availability and quality of stored RBCsW Dzik
Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Transfus Med 18:260-5. 2008..Given the fundamental importance of a safe and adequate blood supply to national healthcare, the question of the proper storage age for blood should be studied using a prospective study design...
When monocytes and platelets compete: The effect of platelet count on the flow cytometric measurement of monocyte CD36W H Dzik
Harvard Medical School, Massachusetts General Hospital, Department of Pathology, Boston, MA 02114, USA
Cytometry B Clin Cytom 78:81-7. 2010..CD36 is also strongly expressed on platelets where it is also known as platelet glycoprotein IV...
The air we breathe: three vital respiratory gases and the red blood cell: oxygen, nitric oxide, and carbon dioxideWalter H Dzik
Blood Transfusion Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Transfusion 51:676-85. 2011..Just as individual cells depend on balance of the three vital gases, so too will their balance determine survival of life on Earth...
Predicting hemorrhage using preoperative coagulation screening assaysWalter H Dzik
Blood Transfusion Service, J 224, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Curr Hematol Rep 3:324-30. 2004....
Toward standardization of CD34+ cell enumeration: an international study. Biomedial Excellence for Safer Transfusion Working PartyW Dzik
Blood Transfusion Service, Massachusetts General Hospital, Boston 02114, USA
Transfusion 39:856-63. 1999..Two commercially available techniques were studied, a flow cytometry method and a microvolume fluorimetry method...
A multicenter study evaluating three methods for counting residual WBCs in WBC-reduced blood components: Nageotte hemocytometry, flow cytometry, and microfluorometryS Dzik
Blood Transfusion Service, Massachusetts General Hospital, Boston, MA 02114, USA
Transfusion 40:513-20. 2000..A multicenter study was conducted to evaluate the performance characteristics of flow cytometry and microfluorimetry for counting low concentrations of WBCs and to compare the results with Nageotte hemocytometry...
Transfusion safety, 2001W H Dzik
Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
Dev Biol (Basel) 108:3-7. 2002
Leukoreduction of blood componentsWalter H Dzik
Blood Transfusion Service, Massachusetts General Hospital, Boston, 02114, USA
Curr Opin Hematol 9:521-6. 2002..The application of the technology to all blood components does not appear to be warranted...
A prospective, randomized clinical trial of universal WBC reductionW H Dzik
Blood Transfusion Service, Massachusetts General Hospital, Boston 02114, USA
Transfusion 42:1114-22. 2002..Recipient exposure to allogeneic donor WBCs results in transfusion complications for selected populations of recipients. Whether or not WBC reduction should be universally applied is highly controversial...
Apoptosis, transforming growth factor-beta, and the immunosuppressive effect of transfusionSunny Dzik
Blood Transfusion Service, Massachusetts General Hospital, Boston 02114, USA
Transfusion 42:1221-3. 2002
Cardinal signs of reactions: hypotension following blood transfusionWalter H Dzik
Blood Transfusion Service J-224, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Vox Sang 83:145-6. 2002
An alternative mechanism for the immunosuppressive effect of transfusionWalter H Dzik
Blood Transfusion Service, J-224, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Vox Sang 83:417-9. 2002
An international study of the performance of sample collection from patientsW H Dzik
Blood Transfusion Service, Massachusetts General Hospital, Boston 02114, USA
Vox Sang 85:40-7. 2003..The aim of this international collaborative study was to assess the frequency of mislabelled and miscollected samples drawn for blood grouping...
Emily Cooley Lecture 2002: transfusion safety in the hospitalWalter H Dzik
Blood Transfusion Service, JJ-224 Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Transfusion 43:1190-9. 2003
Apoptosis, TGF beta and transfusion-related immunosuppression: Biologic versus clinical effectsWalter H Dzik
Blood Transfusion Service, J 224, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Transfus Apher Sci 29:127-9. 2003..The infusion of apoptotic cells has recently been shown in animal models to be immunosuppressive. Immunosuppression resulting from the infusion of apoptotic cells may be linked to transforming growth factor beta (TGF-beta)...
Patient safety and blood transfusion: new solutionsWalter H Dzik
Department of Hematology Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
Transfus Med Rev 17:169-80. 2003..Technology solutions will likely require integration with delivery of pharmaceuticals to be financially acceptable to hospitals...
Management of thrombolysis-associated symptomatic intracerebral hemorrhageJoshua N Goldstein
Department of Emergency Medicine, Massachusetts General Hospital, Zero Emerson Place, STE 3B, Boston, MA 02114, USA
Arch Neurol 67:965-9. 2010..It is not clear whether patients with sICH continue to bleed after diagnosis, nor has the most appropriate treatment been determined...
Transfusion-related acute lung injury or acute chest syndrome of sickle cell disease? - A case reportPaul G Firth
Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, USA
Can J Anaesth 50:895-9. 2003..To describe how to differentiate transfusion-related acute lung injury from acute chest syndrome of sickle cell disease...
Effect of fresh-frozen plasma transfusion on prothrombin time and bleeding in patients with mild coagulation abnormalitiesOmar I Abdel-Wahab
Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Transfusion 46:1279-85. 2006..CONCLUSION: It is concluded that transfusion of FFP for mild abnormalities of coagulation values results in partial normalization of PT in a minority of patients and fails to correct the PT in 99 percent of patients...
Treatment of recurrent allograft dysfunction with intravenous hematin after liver transplantation for erythropoietic protoporphyriaEvan S Dellon
Medical Service Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Transplantation 73:911-5. 2002..This is the first case of the use of hematin given post-OLT to help achieve and maintain remission of allograft EPP disease...
Case records of the Massachusetts General Hospital. Case 32-2006. A 3-year-old girl with fever after a visit to AfricaIain P Fraser
Department of Pediatrics, Massachusetts General Hospital, USA
N Engl J Med 355:1715-22. 2006
Current usage of intravenous immune globulin and the rationale behind it: the Massachusetts General Hospital data and a review of the literatureKamran Darabi
Harvard University Joint Program in Transfusion Medicine, Boston, Massachusetts, USA
Transfusion 46:741-53. 2006..However, most usage is for off-label indications, and for some of these comprehensive guidelines have been published...
Testing only donors with a prior history of pregnancy or transfusion is a logical and cost-effective transfusion-related acute lung injury prevention strategyAmy Powers
Blood Transfusion Service, Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Transfusion 48:2549-58. 2008..Donor screening may reduce TRALI risk. This study sought to compare the efficacy and safety of different TRALI risk-reduction strategies at a hospital-based donor center...
Red blood cell exchange transfusion in two patients with advanced erythropoietic protoporphyriaQuentin G Eichbaum
Department of Pathology, Division of Laboratoty Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Transfusion 45:208-13. 2005..The effectiveness of RBC exchange plus hematin versus plasmapheresis plus hematin in two patients with advanced hepatic EPP is reported...
Research Grants
- Studies of rHuTPO in ITP and of rVlla in Liver DiseaseDavid Kuter; Fiscal Year: 2006..Study endpoints would include (a) the percentage of patients increasing the platelet count over 50x109/L, (b) the number of RBC and platelet transfusions at splenectomy, (c) the rate of adverse events. ..
