Sunny Dzik

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Predicting hemorrhage using preoperative coagulation screening assays
    Walter H Dzik
    Blood Transfusion Service, J 224, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Curr Hematol Rep 3:324-30. 2004
  2. pmc Inter-relationships of cardinal features and outcomes of symptomatic pediatric Plasmodium falciparum MALARIA in 1,933 children in Kampala, Uganda
    Christine M Cserti-Gazdewich
    University Health Network, University of Toronto, Toronto, Canada
    Am J Trop Med Hyg 88:747-56. 2013
  3. pmc The effect of blood storage age on treatment of lactic acidosis by transfusion in children with severe malarial anaemia: a pilot, randomized, controlled trial
    Aggrey Dhabangi
    Child Health and Development Centre, Makerere University, Kampala, Uganda
    Malar J 12:55. 2013
  4. doi request reprint Reversal of drug-induced anticoagulation: old solutions and new problems
    Walter Sunny Dzik
    Blood Transfusion Service, J 224 Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Transfusion 52:45S-55S. 2012
  5. pmc Clinical review: Canadian National Advisory Committee on Blood and Blood Products--Massive transfusion consensus conference 2011: report of the panel
    Walter H Dzik
    Blood Transfusion Service, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Crit Care 15:242. 2011
  6. pmc Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in Uganda
    Christine M Cserti-Gazdewich
    Department of Laboratory Medicine and Pathobiology, University Health Network University of Toronto, Canada
    Malar J 9:233. 2010
  7. ncbi request reprint The NHLBI Clinical Trials Network in transfusion medicine and hemostasis: an overview
    Walter H Dzik
    Blood Transfusion Service, Boston, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA
    J Clin Apher 21:57-9. 2006
  8. ncbi request reprint Off-label reports of new biologics: exciting new therapy or dubious research? Examples from recombinant activated factor VII
    Walter H Dzik
    Blood Tranfusion Service, Massachusetts General Hospital, Boston, 02114, USA
    J Intensive Care Med 21:54-9. 2006
  9. ncbi request reprint New technology for transfusion safety
    Walter H Dzik
    Massachusetts General Hospital, Boston, MA 02114, USA
    Br J Haematol 136:181-90. 2007
  10. ncbi request reprint How I do it: platelet support for refractory patients
    Sunny Dzik
    Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Transfusion 47:374-8. 2007

Research Grants

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Predicting hemorrhage using preoperative coagulation screening assays
    Walter H Dzik
    Blood Transfusion Service, J 224, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Curr Hematol Rep 3:324-30. 2004
    ....
  2. pmc Inter-relationships of cardinal features and outcomes of symptomatic pediatric Plasmodium falciparum MALARIA in 1,933 children in Kampala, Uganda
    Christine M Cserti-Gazdewich
    University Health Network, University of Toronto, Toronto, Canada
    Am J Trop Med Hyg 88:747-56. 2013
    ..clinicaltrials.gov)...
  3. pmc The effect of blood storage age on treatment of lactic acidosis by transfusion in children with severe malarial anaemia: a pilot, randomized, controlled trial
    Aggrey Dhabangi
    Child Health and Development Centre, Makerere University, Kampala, Uganda
    Malar J 12:55. 2013
    ..The objective of this pilot study was to evaluate the effect of blood storage age on resolution of lactic acidosis in children with severe malarial anaemia and demonstrate feasibility of conducting a large trial...
  4. doi request reprint Reversal of drug-induced anticoagulation: old solutions and new problems
    Walter Sunny Dzik
    Blood Transfusion Service, J 224 Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Transfusion 52:45S-55S. 2012
    ..This review is presented to assist transfusion medicine specialists, hematologists, and other clinicians who prescribe blood components for reversal of drug-induced anticoagulation...
  5. pmc Clinical review: Canadian National Advisory Committee on Blood and Blood Products--Massive transfusion consensus conference 2011: report of the panel
    Walter H Dzik
    Blood Transfusion Service, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Crit Care 15:242. 2011
    ..The present report is intended to provide guidance to practitioners, hospitals, and policy-makers...
  6. pmc Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in Uganda
    Christine M Cserti-Gazdewich
    Department of Laboratory Medicine and Pathobiology, University Health Network University of Toronto, Canada
    Malar J 9:233. 2010
    ..falciparum infection exhibiting a spectrum of clinical severity...
  7. ncbi request reprint The NHLBI Clinical Trials Network in transfusion medicine and hemostasis: an overview
    Walter H Dzik
    Blood Transfusion Service, Boston, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA
    J Clin Apher 21:57-9. 2006
    ..Examples of clinical trials currently in the network "pipeline" are briefly summarized as an overview to more detailed presentations given elsewhere in this symposium...
  8. ncbi request reprint Off-label reports of new biologics: exciting new therapy or dubious research? Examples from recombinant activated factor VII
    Walter H Dzik
    Blood Tranfusion Service, Massachusetts General Hospital, Boston, 02114, USA
    J Intensive Care Med 21:54-9. 2006
  9. ncbi request reprint New technology for transfusion safety
    Walter H Dzik
    Massachusetts General Hospital, Boston, MA 02114, USA
    Br J Haematol 136:181-90. 2007
    ....
  10. ncbi request reprint How I do it: platelet support for refractory patients
    Sunny Dzik
    Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Transfusion 47:374-8. 2007
  11. ncbi request reprint The James Blundell Award Lecture 2006: transfusion and the treatment of haemorrhage: past, present and future
    W H Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusettes, USA
    Transfus Med 17:367-74. 2007
    ..Ultimately, the application of widescale genomics testing will refresh our understanding of human physiology and will reassert the importance of the individual in patient care...
  12. doi request reprint Errors in patient specimen collection: application of statistical process control
    Walter Sunny Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Transfusion 48:2143-51. 2008
    ..Statistical process control (SPC) is a recognized method to monitor the performance of a critical process. An easy-to-use SPC method was tested to determine its feasibility as a tool for monitoring quality in transfusion medicine...
  13. doi request reprint Fresh blood for everyone? Balancing availability and quality of stored RBCs
    W Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Transfus Med 18:260-5. 2008
    ..Given the fundamental importance of a safe and adequate blood supply to national healthcare, the question of the proper storage age for blood should be studied using a prospective study design...
  14. doi request reprint When monocytes and platelets compete: The effect of platelet count on the flow cytometric measurement of monocyte CD36
    W H Dzik
    Harvard Medical School, Massachusetts General Hospital, Department of Pathology, Boston, MA 02114, USA
    Cytometry B Clin Cytom 78:81-7. 2010
    ..CD36 is also strongly expressed on platelets where it is also known as platelet glycoprotein IV...
  15. doi request reprint The air we breathe: three vital respiratory gases and the red blood cell: oxygen, nitric oxide, and carbon dioxide
    Walter H Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Transfusion 51:676-85. 2011
    ..Just as individual cells depend on balance of the three vital gases, so too will their balance determine survival of life on Earth...
  16. ncbi request reprint The impact of the National Blood Foundation
    Walter H Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Boston, Massachusetts, 02114, USA
    Transfusion 45:41S-3S. 2005
  17. ncbi request reprint Toward standardization of CD34+ cell enumeration: an international study. Biomedial Excellence for Safer Transfusion Working Party
    W Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Boston 02114, USA
    Transfusion 39:856-63. 1999
    ..Two commercially available techniques were studied, a flow cytometry method and a microvolume fluorimetry method...
  18. ncbi request reprint A multicenter study evaluating three methods for counting residual WBCs in WBC-reduced blood components: Nageotte hemocytometry, flow cytometry, and microfluorometry
    S Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Boston, MA 02114, USA
    Transfusion 40:513-20. 2000
    ..A multicenter study was conducted to evaluate the performance characteristics of flow cytometry and microfluorimetry for counting low concentrations of WBCs and to compare the results with Nageotte hemocytometry...
  19. ncbi request reprint Transfusion safety, 2001
    W H Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Dev Biol (Basel) 108:3-7. 2002
  20. ncbi request reprint Leukoreduction of blood components
    Walter H Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Boston, 02114, USA
    Curr Opin Hematol 9:521-6. 2002
    ..The application of the technology to all blood components does not appear to be warranted...
  21. ncbi request reprint A prospective, randomized clinical trial of universal WBC reduction
    W H Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Boston 02114, USA
    Transfusion 42:1114-22. 2002
    ..Recipient exposure to allogeneic donor WBCs results in transfusion complications for selected populations of recipients. Whether or not WBC reduction should be universally applied is highly controversial...
  22. ncbi request reprint Apoptosis, transforming growth factor-beta, and the immunosuppressive effect of transfusion
    Sunny Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Boston 02114, USA
    Transfusion 42:1221-3. 2002
  23. ncbi request reprint Cardinal signs of reactions: hypotension following blood transfusion
    Walter H Dzik
    Blood Transfusion Service J 224, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Vox Sang 83:145-6. 2002
  24. ncbi request reprint An alternative mechanism for the immunosuppressive effect of transfusion
    Walter H Dzik
    Blood Transfusion Service, J 224, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Vox Sang 83:417-9. 2002
  25. ncbi request reprint An international study of the performance of sample collection from patients
    W H Dzik
    Blood Transfusion Service, Massachusetts General Hospital, Boston 02114, USA
    Vox Sang 85:40-7. 2003
    ..The aim of this international collaborative study was to assess the frequency of mislabelled and miscollected samples drawn for blood grouping...
  26. ncbi request reprint Patient safety and blood transfusion: new solutions
    Walter H Dzik
    Department of Hematology Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Transfus Med Rev 17:169-80. 2003
    ..Technology solutions will likely require integration with delivery of pharmaceuticals to be financially acceptable to hospitals...
  27. ncbi request reprint Apoptosis, TGF beta and transfusion-related immunosuppression: Biologic versus clinical effects
    Walter H Dzik
    Blood Transfusion Service, J 224, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Transfus Apher Sci 29:127-9. 2003
    ..The infusion of apoptotic cells has recently been shown in animal models to be immunosuppressive. Immunosuppression resulting from the infusion of apoptotic cells may be linked to transforming growth factor beta (TGF-beta)...
  28. ncbi request reprint Emily Cooley Lecture 2002: transfusion safety in the hospital
    Walter H Dzik
    Blood Transfusion Service, JJ 224 Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Transfusion 43:1190-9. 2003
  29. ncbi request reprint Radio frequency identification for prevention of bedside errors
    Sunny Dzik
    Massachusettes General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Transfusion 47:125S-129S; discussion 130S-131S. 2007
  30. pmc Management of thrombolysis-associated symptomatic intracerebral hemorrhage
    Joshua N Goldstein
    Department of Emergency Medicine, Massachusetts General Hospital, Zero Emerson Place, STE 3B, Boston, MA 02114, USA
    Arch Neurol 67:965-9. 2010
    ..It is not clear whether patients with sICH continue to bleed after diagnosis, nor has the most appropriate treatment been determined...
  31. ncbi request reprint Transfusion-related acute lung injury or acute chest syndrome of sickle cell disease? - A case report
    Paul G Firth
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, USA
    Can J Anaesth 50:895-9. 2003
    ..To describe how to differentiate transfusion-related acute lung injury from acute chest syndrome of sickle cell disease...
  32. ncbi request reprint Use of a computer-assisted system for blood utilization review
    Sunny Dzik
    Mass General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Transfusion 47:142S-144S; discussion 155S-156S. 2007
  33. ncbi request reprint A touch of TRALI
    Amanda Davis
    Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114 2696, USA
    Transfusion 48:541-5. 2008
    ..Benefits in recognizing mild cases of TRALI include quantifying the true incidence of TRALI, understanding the physiology of mild versus severe TRALI, and preventing subsequent cases of TRALI due to donors found to have HLA antibodies...
  34. ncbi request reprint Effect of fresh-frozen plasma transfusion on prothrombin time and bleeding in patients with mild coagulation abnormalities
    Omar I Abdel-Wahab
    Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Transfusion 46:1279-85. 2006
    ....
  35. ncbi request reprint Hyperhemolysis syndrome in anemia of chronic disease
    Kamran Darabi
    Harvard University Joint Program in Transfusion Medicine and Blood Transfusion Service at Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Transfusion 45:1930-3. 2005
    ..This syndrome usually occurs in patients with sickle cell disease and possibly thalassemia who receive multiple transfusions. There are few such clinical reports in patients without hemoglobinopathies...
  36. ncbi request reprint Case records of the Massachusetts General Hospital. Case 32-2006. A 3-year-old girl with fever after a visit to Africa
    Iain P Fraser
    Department of Pediatrics, Massachusetts General Hospital, USA
    N Engl J Med 355:1715-22. 2006
  37. ncbi request reprint Treatment of recurrent allograft dysfunction with intravenous hematin after liver transplantation for erythropoietic protoporphyria
    Evan S Dellon
    Medical Service Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Transplantation 73:911-5. 2002
    ..This is the first case of the use of hematin given post-OLT to help achieve and maintain remission of allograft EPP disease...
  38. ncbi request reprint Current usage of intravenous immune globulin and the rationale behind it: the Massachusetts General Hospital data and a review of the literature
    Kamran Darabi
    Harvard University Joint Program in Transfusion Medicine, Boston, Massachusetts, USA
    Transfusion 46:741-53. 2006
    ..However, most usage is for off-label indications, and for some of these comprehensive guidelines have been published...
  39. ncbi request reprint Testing only donors with a prior history of pregnancy or transfusion is a logical and cost-effective transfusion-related acute lung injury prevention strategy
    Amy Powers
    Blood Transfusion Service, Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Transfusion 48:2549-58. 2008
    ..Donor screening may reduce TRALI risk. This study sought to compare the efficacy and safety of different TRALI risk-reduction strategies at a hospital-based donor center...
  40. ncbi request reprint Red blood cell exchange transfusion in two patients with advanced erythropoietic protoporphyria
    Quentin G Eichbaum
    Department of Pathology, Division of Laboratoty Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Transfusion 45:208-13. 2005
    ..The effectiveness of RBC exchange plus hematin versus plasmapheresis plus hematin in two patients with advanced hepatic EPP is reported...

Research Grants1

  1. Studies of rHuTPO in ITP and of rVlla in Liver Disease
    David Kuter; Fiscal Year: 2006
    ..Study endpoints would include (a) the percentage of patients increasing the platelet count over 50x109/L, (b) the number of RBC and platelet transfusions at splenectomy, (c) the rate of adverse events. ..