Jonathan M Dreyfuss

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers
    Jonathan M Dreyfuss
    Partners Healthcare Center for Personalized Genetic Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Mol Cancer 8:71. 2009
  2. pmc Expression profiling of uterine leiomyomata cytogenetic subgroups reveals distinct signatures in matched myometrium: transcriptional profilingof the t(12;14) and evidence in support of predisposing genetic heterogeneity
    Jennelle C Hodge
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Hum Mol Genet 21:2312-29. 2012
  3. ncbi request reprint Upregulation of proapoptotic microRNA mir-125a after massive small bowel resection in rats
    Anita Balakrishnan
    Department of Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    Ann Surg 255:747-53. 2012
  4. pmc Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma
    Sam S Yoon
    Department of Surgery, Division of Surgical Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 74:1207-16. 2009
  5. pmc Identifying the molecular signature of the interstitial deletion 7q subgroup of uterine leiomyomata using a paired analysis
    Jennelle C Hodge
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Genes Chromosomes Cancer 48:865-85. 2009
  6. pmc Unphosphorylated SR-like protein Npl3 stimulates RNA polymerase II elongation
    JESSICA L DERMODY
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA
    PLoS ONE 3:e3273. 2008
  7. pmc MicroRNA mir-16 is anti-proliferative in enterocytes and exhibits diurnal rhythmicity in intestinal crypts
    Anita Balakrishnan
    Department of Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    Exp Cell Res 316:3512-21. 2010

Collaborators

Detail Information

Publications7

  1. pmc Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers
    Jonathan M Dreyfuss
    Partners Healthcare Center for Personalized Genetic Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Mol Cancer 8:71. 2009
    ..Although genomewide profiling of expression levels with microarrays can be used to identify differentially expressed genes between these tumor types, comparative studies so far have resulted in gene lists that show little overlap...
  2. pmc Expression profiling of uterine leiomyomata cytogenetic subgroups reveals distinct signatures in matched myometrium: transcriptional profilingof the t(12;14) and evidence in support of predisposing genetic heterogeneity
    Jennelle C Hodge
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Hum Mol Genet 21:2312-29. 2012
    ..This suggests an underlying constitutional genetic predisposition to these somatic changes which could potentially lead to improved personalized management and treatment...
  3. ncbi request reprint Upregulation of proapoptotic microRNA mir-125a after massive small bowel resection in rats
    Anita Balakrishnan
    Department of Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    Ann Surg 255:747-53. 2012
    ..To identify new treatments we focused on postresection changes in microRNAs--short noncoding RNAs, which suppress target genes--and suggest a previously undiscovered role for microRNA-125a (mir-125a) in intestinal adaptation...
  4. pmc Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma
    Sam S Yoon
    Department of Surgery, Division of Surgical Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 74:1207-16. 2009
    ..The present study examined SU and radiotherapy (RT) in a genetically engineered mouse model of soft tissue sarcoma (STS)...
  5. pmc Identifying the molecular signature of the interstitial deletion 7q subgroup of uterine leiomyomata using a paired analysis
    Jennelle C Hodge
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Genes Chromosomes Cancer 48:865-85. 2009
    ..This study provides a molecular signature of the del(7q) UL subgroup and will serve as a platform for future studies of tumor pathogenesis...
  6. pmc Unphosphorylated SR-like protein Npl3 stimulates RNA polymerase II elongation
    JESSICA L DERMODY
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA
    PLoS ONE 3:e3273. 2008
    ..This work defines a novel role for Npl3 in elongation and its regulation by phosphorylation...
  7. pmc MicroRNA mir-16 is anti-proliferative in enterocytes and exhibits diurnal rhythmicity in intestinal crypts
    Anita Balakrishnan
    Department of Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    Exp Cell Res 316:3512-21. 2010
    ..The regulatory mechanisms behind these rhythms remain largely unknown. We hypothesized that microRNAs are involved in mediating these rhythms, and studied the role of microRNAs specifically in modulating intestinal proliferation...