David M Dorfman
Affiliation: Massachusetts General Hospital
Dorfman D, Brown J, Shahsafaei A, Freeman G. Programmed death-1 (PD-1) is a marker of germinal center-associated T cells and angioimmunoblastic T-cell lymphoma. Am J Surg Pathol. 2006;30:802-10 pubmed
Dorfman D, Shahsafaei A. CD200 (OX-2 membrane glycoprotein) expression in b cell-derived neoplasms. Am J Clin Pathol. 2010;134:726-33 pubmed publisher
..Furthermore, since an anti-CD200 immunotherapeutic agent is in clinical trials, a number of B cell-derived neoplasms in addition to CLL/SLL may be suitable therapeutic targets. ..
Dorfman D, Shahsafaei A, Alonso M. Utility of CD200 immunostaining in the diagnosis of primary mediastinal large B cell lymphoma: comparison with MAL, CD23, and other markers. Mod Pathol. 2012;25:1637-43 pubmed publisher
..We conclude that CD200 is a practical and useful marker for the diagnosis of primary mediastinal large B cell lymphoma. ..
Dorfman D, Laplante C, Pozdnyakova O, Li B. FLOCK cluster analysis of mast cell event clustering by high-sensitivity flow cytometry predicts systemic mastocytosis. Am J Clin Pathol. 2015;144:764-70 pubmed publisher
..FLOCK analysis provides useful diagnostic information for evaluating patients with suspected SM, and may be useful for the analysis of other hematopoietic neoplasms. ..
Dorfman D, Laplante C, Li B. FLOCK cluster analysis of plasma cell flow cytometry data predicts bone marrow involvement by plasma cell neoplasia. Leuk Res. 2016;48:40-5 pubmed publisher
Dorfman D, Morgan E, Pelton A, Unitt C. T-cell transcription factor GATA-3 is an immunophenotypic marker of acute leukemias with T-cell differentiation. Hum Pathol. 2017;65:166-174 pubmed publisher
Dorfman D, Hornick J, Shahsafaei A, Freeman G. The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms. Hum Pathol. 2010;41:1486-94 pubmed publisher
..We conclude that histiocytic and dendritic cell neoplasms consistently express TIM-3 and TIM-4 and that these molecules are new markers of neoplasms derived from histiocytic and dendritic cells...