Lingsheng Dong

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Differentially expressed alternatively spliced genes in malignant pleural mesothelioma identified using massively parallel transcriptome sequencing
    Lingsheng Dong
    The Thoracic Surgery Oncology Laboratory and Division of Thoracic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMC Med Genet 10:149. 2009
  2. pmc Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma
    Gavin J Gordon
    Department of Surgery, Division of Thoracic Surgery, Harvard Medical School and Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    J Natl Cancer Inst 101:678-86. 2009
  3. pmc Second generation sequencing of the mesothelioma tumor genome
    Raphael Bueno
    The International Mesothelioma Program, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 5:e10612. 2010
  4. pmc Fine-needle aspiration biopsies for gene expression ratio-based diagnostic and prognostic tests in malignant pleural mesothelioma
    Assunta De Rienzo
    The Thoracic Surgery Oncology Laboratory and International Mesothelioma Program, and Division of Thoracic Surgery, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Clin Cancer Res 17:310-6. 2011
  5. pmc Transcriptome sequencing of malignant pleural mesothelioma tumors
    David J Sugarbaker
    International Mesothelioma Program, Division of Thoracic Surgery, Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 105:3521-6. 2008
  6. pmc Gene Expression Ratio Test Distinguishes Normal Lung from Lung Tumors in Solid Tissue and FNA Biopsies
    Assunta De Rienzo
    Thoracic Surgery Oncology Laboratory and the International Mesothelioma Program, Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Massachusetts Department of Surgery, Harvard Medical School, Boston, Massachusetts
    J Mol Diagn 16:267-72. 2014
  7. pmc A gene expression ratio-based diagnostic test for bladder cancer
    Lingsheng Dong
    The Thoracic Surgery Oncology Laboratory and the Division of Thoracic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Adv Appl Bioinform Chem 2:17-22. 2009
  8. pmc Drop-on-demand single cell isolation and total RNA analysis
    Sangjun Moon
    Demirci Bio Acoustic MEMS in Medicine BAMM Laboratory, Center for Bioengineering, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 6:e17455. 2011

Collaborators

Detail Information

Publications8

  1. pmc Differentially expressed alternatively spliced genes in malignant pleural mesothelioma identified using massively parallel transcriptome sequencing
    Lingsheng Dong
    The Thoracic Surgery Oncology Laboratory and Division of Thoracic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMC Med Genet 10:149. 2009
    ..We hypothesized that alternative splicing profiles might be detected in the sequencing data for the expressed genes in these samples...
  2. pmc Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma
    Gavin J Gordon
    Department of Surgery, Division of Thoracic Surgery, Harvard Medical School and Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    J Natl Cancer Inst 101:678-86. 2009
    ..In this study, we investigated the predictive value and technical assay performance of this test in patients with malignant pleural mesothelioma...
  3. pmc Second generation sequencing of the mesothelioma tumor genome
    Raphael Bueno
    The International Mesothelioma Program, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 5:e10612. 2010
    ..Second-generation sequencing uncovered all types of mutations in this MPM tumor, with DNA rearrangements representing the dominant type...
  4. pmc Fine-needle aspiration biopsies for gene expression ratio-based diagnostic and prognostic tests in malignant pleural mesothelioma
    Assunta De Rienzo
    The Thoracic Surgery Oncology Laboratory and International Mesothelioma Program, and Division of Thoracic Surgery, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Clin Cancer Res 17:310-6. 2011
    ..We postulated that the accuracy of FNA-based diagnosis might be improved by the addition of molecular tests using a gene expression ratio-based algorithm and that prognostic tests could be similarly performed...
  5. pmc Transcriptome sequencing of malignant pleural mesothelioma tumors
    David J Sugarbaker
    International Mesothelioma Program, Division of Thoracic Surgery, Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 105:3521-6. 2008
    ..Of the seven point mutations, three were observed in at least one tumor from 49 other MPM patients. The mutations were in genes that could be causally related to cancer and included XRCC6, PDZK1IP1, ACTR1A, and AVEN...
  6. pmc Gene Expression Ratio Test Distinguishes Normal Lung from Lung Tumors in Solid Tissue and FNA Biopsies
    Assunta De Rienzo
    Thoracic Surgery Oncology Laboratory and the International Mesothelioma Program, Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Massachusetts Department of Surgery, Harvard Medical School, Boston, Massachusetts
    J Mol Diagn 16:267-72. 2014
    ..This study supports the hypothesis that the gene-ratio approach reliably distinguishes normal lung from cancerous tissues in FNA samples and can be optimized to diagnose benign nodules. ..
  7. pmc A gene expression ratio-based diagnostic test for bladder cancer
    Lingsheng Dong
    The Thoracic Surgery Oncology Laboratory and the Division of Thoracic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Adv Appl Bioinform Chem 2:17-22. 2009
    ..In this study, we sought to determine whether this technique could be applied to the diagnosis of bladder cancer...
  8. pmc Drop-on-demand single cell isolation and total RNA analysis
    Sangjun Moon
    Demirci Bio Acoustic MEMS in Medicine BAMM Laboratory, Center for Bioengineering, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 6:e17455. 2011
    ..This automated platform enabling high-throughput cell manipulation for subsequent genomic analysis employs fewer handling steps compared to existing methods...