Affiliation: Massachusetts General Hospital
Hwang D, Sholl L, Rojas Rudilla V, Hall D, Shivdasani P, Garcia E, et al
. KRAS and NKX2-1 Mutations in Invasive Mucinous Adenocarcinoma of the Lung. J Thorac Oncol. 2016;11:496-503 pubmed publisher
..1) and expression of gastrointestinalÂ markers. These findings describe recurrent NKX2-1 mutations in invasive mucinous adenocarcinomas of the lung and support NKX2-1 as a lineage-specific tumor suppressor gene in lung carcinogenesis. ..
Dong F, Davineni P, Howitt B, Beck A. A BRCA1/2 Mutational Signature and Survival in Ovarian High-Grade Serous Carcinoma. Cancer Epidemiol Biomarkers Prev. 2016;25:1511-1516 pubmed
..This study identifies the use of mutational signatures as a biomarker for survival outcome in ovarian high-grade serous carcinoma. Cancer Epidemiol Biomarkers Prev; 25(11); 1511-6. Â©2016 AACR. ..
Nowak J, Yurgelun M, Bruce J, Rojas Rudilla V, Hall D, Shivdasani P, et al
. Detection of Mismatch Repair Deficiency and Microsatellite Instability in Colorectal Adenocarcinoma by Targeted Next-Generation Sequencing. J Mol Diagn. 2017;19:84-91 pubmed publisher
..These findings provide a framework for a targeted tumor sequencing panel to accurately detect MMR-D and MSI-H in colorectal carcinomas. ..