Akshay Desai

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint Are serial BNP measurements useful in heart failure management? Serial natriuretic peptide measurements are not useful in heart failure management: the art of medicine remains long
    Akshay S Desai
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Circulation 127:509-16; discussion 516. 2013
  2. doi request reprint Central aortic stiffness is increased in patients with heart failure and preserved ejection fraction
    Akshay S Desai
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Card Fail 15:658-64. 2009
  3. ncbi request reprint Hyperkalemia in patients with heart failure: incidence, prevalence, and management
    Akshay S Desai
    Advanced Heart Disease Section, PBB A3 AB370, Cardiovascular Division, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Curr Heart Fail Rep 6:272-80. 2009
  4. doi request reprint Impact of erythropoiesis-stimulating agents on morbidity and mortality in patients with heart failure: an updated, post-TREAT meta-analysis
    Akshay Desai
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA, USA
    Eur J Heart Fail 12:936-42. 2010
  5. doi request reprint Heart failure with preserved ejection fraction: hypertension, diabetes, obesity/sleep apnea, and hypertrophic and infiltrative cardiomyopathy
    Akshay Desai
    Brigham and Women s Hospital, Boston, MA 02115, USA
    Heart Fail Clin 4:87-97. 2008
  6. ncbi request reprint Incidence and predictors of hyperkalemia in patients with heart failure: an analysis of the CHARM Program
    Akshay S Desai
    Department of Cardiology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 50:1959-66. 2007
  7. ncbi request reprint Current understanding of heart failure with preserved ejection fraction
    Akshay Desai
    Advanced Herat Disease Section, Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02445, USA
    Curr Opin Cardiol 22:578-85. 2007
  8. ncbi request reprint Diabetes and heart failure: epidemiology, pathophysiology and management
    Akshay S Desai
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, USA
    Indian Heart J 57:295-303. 2005
  9. ncbi request reprint Implantable defibrillators for the prevention of mortality in patients with nonischemic cardiomyopathy: a meta-analysis of randomized controlled trials
    Akshay S Desai
    Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    JAMA 292:2874-9. 2004
  10. doi request reprint Rationale and design of the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial: a randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction
    Akshay S Desai
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am Heart J 162:966-972.e10. 2011

Detail Information

Publications27

  1. doi request reprint Are serial BNP measurements useful in heart failure management? Serial natriuretic peptide measurements are not useful in heart failure management: the art of medicine remains long
    Akshay S Desai
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Circulation 127:509-16; discussion 516. 2013
  2. doi request reprint Central aortic stiffness is increased in patients with heart failure and preserved ejection fraction
    Akshay S Desai
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Card Fail 15:658-64. 2009
    ..Although heart failure in hypertensive patients is usually ascribed to intrinsic myocardial abnormalities, noncardiac factors may contribute...
  3. ncbi request reprint Hyperkalemia in patients with heart failure: incidence, prevalence, and management
    Akshay S Desai
    Advanced Heart Disease Section, PBB A3 AB370, Cardiovascular Division, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Curr Heart Fail Rep 6:272-80. 2009
    ....
  4. doi request reprint Impact of erythropoiesis-stimulating agents on morbidity and mortality in patients with heart failure: an updated, post-TREAT meta-analysis
    Akshay Desai
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA, USA
    Eur J Heart Fail 12:936-42. 2010
    ..We therefore examined the effect of treating anaemia with an ESA in patients with heart failure in a meta-analysis of randomized clinical trials, including the recently reported TREAT study...
  5. doi request reprint Heart failure with preserved ejection fraction: hypertension, diabetes, obesity/sleep apnea, and hypertrophic and infiltrative cardiomyopathy
    Akshay Desai
    Brigham and Women s Hospital, Boston, MA 02115, USA
    Heart Fail Clin 4:87-97. 2008
    ..The article concludes with a brief discussion of "primary" diastolic HF due to infiltrative or restrictive cardiomyopathies...
  6. ncbi request reprint Incidence and predictors of hyperkalemia in patients with heart failure: an analysis of the CHARM Program
    Akshay S Desai
    Department of Cardiology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 50:1959-66. 2007
    ..We explored the incidence and predictors of hyperkalemia in a broad population of heart failure patients...
  7. ncbi request reprint Current understanding of heart failure with preserved ejection fraction
    Akshay Desai
    Advanced Herat Disease Section, Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02445, USA
    Curr Opin Cardiol 22:578-85. 2007
    ....
  8. ncbi request reprint Diabetes and heart failure: epidemiology, pathophysiology and management
    Akshay S Desai
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, USA
    Indian Heart J 57:295-303. 2005
  9. ncbi request reprint Implantable defibrillators for the prevention of mortality in patients with nonischemic cardiomyopathy: a meta-analysis of randomized controlled trials
    Akshay S Desai
    Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    JAMA 292:2874-9. 2004
    ..However, conclusive evidence of survival benefit in patients with nonischemic cardiomyopathy (NICM) is still lacking...
  10. doi request reprint Rationale and design of the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial: a randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction
    Akshay S Desai
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am Heart J 162:966-972.e10. 2011
    ..Aldosterone, a potent stimulator of myocardial and vascular fibrosis, may be a key mediator of HF progression in this population and is therefore an important therapeutic target...
  11. doi request reprint Effect of intensive versus standard blood pressure lowering on diastolic function in patients with uncontrolled hypertension and diastolic dysfunction
    Scott D Solomon
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Hypertension 55:241-8. 2010
    ....
  12. doi request reprint Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension
    Anne Catherine Pouleur
    Brigham and Women s Hospital, Boston, MA 02115, USA
    J Renin Angiotensin Aldosterone Syst 12:483-90. 2011
    ..High circulating aldosterone levels stimulate myocardial fibrosis and left ventricular hypertrophy (LVH). However, it is not clear whether suppression of aldosterone directly contributes to LVH regression in hypertensive patients...
  13. doi request reprint Age and the effectiveness of anti-hypertensive therapy on improvement in diastolic function
    Susan Cheng
    aBrigham and Women s Hospital, Harvard University, Boston, Massachusetts, USA bNational University Health System, Singapore cNovartis, East Hanover, New Jersey dState University of New York at Buffalo, Buffalo, New York eUniversity of Alabama, Birmingham, Alabama fUniversity of Michigan, Ann Arbor, Michigan, USA
    J Hypertens 32:174-80. 2014
    ..Lowering SBP with antihypertensive therapy has been shown to improve diastolic function, but whether or not age influences this effect is unknown...
  14. doi request reprint Evaluation of a novel antiplatelet agent for secondary prevention in patients with a history of atherosclerotic disease: design and rationale for the Thrombin-Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2 degrees P
    David A Morrow
    TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am Heart J 158:335-341.e3. 2009
    ..Because SCH 530348 does not interfere with other pathways for hemostasis, it is possible that SCH 530348 reduces thrombosis with less increase in bleeding than do other potent antiplatelet agents...
  15. doi request reprint Highlights from the 57th annual scientific session of the American College of Cardiology
    Frederic S Resnic
    Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02492, USA
    J Thorac Cardiovasc Surg 136:244-7. 2008
  16. doi request reprint Images in clinical medicine. Spontaneous thrombolysis of an obstructed mechanical aortic valve
    Nicole Wake
    Brigham and Women s Hospital, Boston, MA 02115, USA
    N Engl J Med 358:e31. 2008
  17. ncbi request reprint Images in cardiovascular medicine. Isolated right ventricular infarction resulting from occlusion of a nondominant right coronary artery
    Shawn A Gregory
    Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Yawkey Center Suite 5800, 55 Fruit St, Boston, MA 02114, USA
    Circulation 110:e500-1. 2004
  18. doi request reprint Impaired skeletal muscle glucose uptake by [18F]fluorodeoxyglucose-positron emission tomography in patients with peripheral artery disease and intermittent claudication
    Reena L Pande
    Brigham and Women s Hospital, Boston, MA 02115, USA
    Arterioscler Thromb Vasc Biol 31:190-6. 2011
    ..We aimed to determine whether skeletal muscle glucose uptake, assessed by [(18)F]fluorodeoxyglucose positron emission tomography, is reduced in patients with claudication...
  19. doi request reprint Patient expectations from implantable defibrillators to prevent death in heart failure
    Garrick C Stewart
    Division of Cardiovascular Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Card Fail 16:106-13. 2010
    ..This study examined patient expectations from ICDs for primary prevention of sudden death in HF...
  20. doi request reprint EXCEED: Exforge-intensive control of hypertension to evaluate efficacy in diastolic dysfunction: study rationale, design, and participant characteristics
    Amira Hassanein
    Brigham and Women s Hospital, Cardiovascular Division, Echo Core lab, Boston, MA 02115, USA
    Ther Adv Cardiovasc Dis 3:429-39. 2009
    ..Both diastolic dysfunction and increased vascular stiffness represent important measures of target-organ damage in hypertension. Whether intensive blood pressure (BP) control can further improve these measures remains unknown...
  21. doi request reprint The effect of renin-angiotensin system inhibitors on mortality and heart failure hospitalization in patients with heart failure and preserved ejection fraction: a systematic review and meta-analysis
    Ravi V Shah
    Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
    J Card Fail 16:260-7. 2010
    ....
  22. ncbi request reprint Economic consequences of routine coronary angiography in low- and intermediate-risk patients with unstable angina pectoris
    Akshay S Desai
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Am J Cardiol 92:363-7. 2003
    ....
  23. doi request reprint Effect of the direct renin inhibitor aliskiren on left ventricular remodelling following myocardial infarction with systolic dysfunction
    Scott D Solomon
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA, USA
    Eur Heart J 32:1227-34. 2011
    ....
  24. ncbi request reprint Therapeutic approaches to diastolic dysfunction
    Rajesh Janardhanan
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Curr Hypertens Rep 11:283-91. 2009
    ....
  25. doi request reprint The association between high-dose diuretics and clinical stability in ambulatory chronic heart failure patients
    Lisa M Mielniczuk
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Card Fail 14:388-93. 2008
    ..In chronic heart failure (HF), diuretic doses increase as the disease progresses, often after hospitalization for instability, and have been associated with worsening renal function and increased mortality...
  26. ncbi request reprint Selecting patients for discussion of the ICD as primary prevention for sudden death in heart failure
    Lynne Warner Stevenson
    Advanced Heart Disease Section, Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Card Fail 12:407-12. 2006
    ..These estimates are presented in the context of adverse events, including unnecessary shocks, and the possibility that circumstances may arise for which the defibrillator may be inactivated to allow natural death...
  27. doi request reprint Clinical predictors of hepatic fibrosis in chronic advanced heart failure
    Jill M Gelow
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA, USA
    Circ Heart Fail 3:59-64. 2010
    ..We investigated the histopathologic spectrum of liver disease in a contemporary population with heart failure to identify the clinical correlates of hepatic fibrosis...